Details of the Drug-Related molecule(s) Interaction Atlas

US9434727, 93 Drug Info

SCHEMBL17222937; CHEMBL3890367; BDBM249495; US9434727, 93

Cross-matching ID

PubChem CID

118483410

TTD Drug ID

DMCJG8Z

General Information of Drug (ID: DMCJG8Z)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Plasma retinol-binding protein (RBP4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tinlarebant	DM6JYUO	Stargardt disease	9B70	Phase 3	[2]
A1-10436	DM9ESPR	N. A.	N. A.	Patented	[3]
US9434727, 153	DMC812I	N. A.	N. A.	Patented	[4]
US9434727, 40	DMLPWK3	N. A.	N. A.	Patented	[5]
US8586571, 12	DMKLJ6O	N. A.	N. A.	Patented	[6]
A1-10438	DMJD1S6	N. A.	N. A.	Patented	[3]
US8586571, 36	DMX3A0O	N. A.	N. A.	Patented	[6]
US8853215, 3	DMX8NLB	N. A.	N. A.	Patented	[3]
US8586571, 6	DM1N74R	N. A.	N. A.	Patented	[6]
US9434727, 120	DMIT0H3	N. A.	N. A.	Patented	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Plasma retinol-binding protein (RBP4)	TT0C8BY	RET4_HUMAN	Inhibitor	[1]

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References

1	Substituted 4-phenylpiperidines, their preparation and use. US10072016.
2	Retinol binding protein 4 antagonists and protein synthesis inhibitors: Potential for therapeutic development. Eur J Med Chem. 2021 Dec 15;226:113856.
3	Derivatives of N-acyl-N-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes. US8853215.
4	Substituted 4-phenylpiperidines, their preparation and use. US9434727.
5	Substituted 4-phenylpiperidines, their preparation and use. US9777010.
6	Heterocyclic compound. US8586571.