Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMDGRQO)

Drug Name
Glycerol phenylbutyrate Drug Info
Synonyms GT4P; HPN-100; Glyceryl tri-(4-phenylbutyrate)
Indication
Disease Entry ICD 11 Status REF
Hepatic encephalopathy DB99.5 Approved [1]
Cross-matching ID
PubChem CID
10482134
ChEBI ID
CHEBI:134745
CAS Number
CAS 611168-24-2
TTD Drug ID
DMDGRQO
INTEDE Drug ID
DR0784

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Aquaporin adipose (AQP7) DEVOTU4 AQP7_HUMAN Substrate [2]
Propanediol dehydrogenase (dhaT) DEDI8VX A0A0C1Q6R1_LACBR Substrate [3]

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Aquaporins in the human testis and spermatozoa - identification, involvement in sperm volume regulation and clinical relevance. Int J Androl. 2010 Aug 1;33(4):629-41.
3 Expression and characterization of a novel 1,3-propanediol dehydrogenase from Lactobacillus brevis. Appl Biochem Biotechnol. 2016 Jul;179(6):959-72.