Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGIS5Q)

• Drug Name: pCMPS Drug Info
• Synonyms: para-Chloromercuriphenylsulfonate; p-Chloromercuribenzenesulfonate; pCMBS

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 11136
  ChEBI ID: CHEBI:33206
  CAS Number: CAS 554-77-8
  TTD Drug ID: DMGIS5Q

Molecule-Related Drug Atlas

Drug(s) Targeting P2Y purinoceptor 12 (P2RY12)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clopidogrel	DMOL54H	Acute coronary syndrome	BA41	Approved	[2]
Prasugrel	DM7MT6E	Acute coronary syndrome	BA41	Approved	[6]
Brilinta	DMBR01X	Acute coronary syndrome	BA41	Approved	[7]
Cangrelor	DM8JRH0	Thrombosis	DB61-GB90	Approved	[8]
INS-50589	DMKZUVC	Cardiovascular disease	BA00-BE2Z	Phase 2	[9]
Elinogrel	DMA4BRV	Myocardial infarction	BA41-BA43	Phase 1	[10]
ARL-67085	DMY5IM2	Thrombosis	DB61-GB90	Phase 1	[11]
adenosine diphosphate	DMFUHKP	N. A.	N. A.	Investigative	[2]
2MeSADP	DMGADQ1	Discovery agent	N.A.	Investigative	[12]
2MeSAMP	DMBO2DC	Discovery agent	N.A.	Investigative	[12]

Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[13]
Clavulanate	DM2FGRT	Bacteremia	1A73	Approved	[14]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[15]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[16]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[17]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[18]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[19]
Reserpine	DM6VM38	Hypertension	BA00-BA04	Approved	[20]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]
Disulfiram	DMCL2OK	Alcohol dependence	6C40.2	Approved	[22]

Drug(s) Affected By Aquaporin-1 (AQP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[23]
Acetazolamide	DM1AF5U	Absence epilepsy		Approved	[24]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[25]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[26]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[27]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[28]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[29]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[30]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[31]
Cytarabine	DMZD5QR	Acute lymphoblastic leukaemia	2A85	Approved	[32]

Drug(s) Affected By Short transient receptor potential channel 5 (TRPC5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Succimer	DME81IY	Metal intoxication	NE60	Approved	[5]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[33]
1,4-Dithiothreitol	DMIFOXE	Discovery agent	N.A.	Investigative	[5]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
P2Y purinoceptor 12 (P2RY12)	TTZ1DT0	P2Y12_HUMAN	Antagonist	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Aldo-keto reductase family 1 member B10 (AKR1B10)	OTOA4HTH	AK1BA_HUMAN	Gene/Protein Processing	[3]
Aquaporin-1 (AQP1)	OTX5MYX9	AQP1_HUMAN	Gene/Protein Processing	[4]
Short transient receptor potential channel 5 (TRPC5)	OTWQFP8F	TRPC5_HUMAN	Gene/Protein Processing	[5]

References

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