Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM2I9G)

Drug Name

ischemin Drug Info

Synonyms

MS120

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting CREB-binding protein (CREBBP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
C 82	DMEWXFK	Scleroderma	4A42	Phase 1/2	[2]
CCS1477	DM9UZM1	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[3]
PRI-724	DM0HTEF	Acute myeloid leukaemia	2A60	Phase 1/2	[4]
FT-7051	DMCK3OI	Prostate cancer	2C82.0	Phase 1	[5]
Pyrrolo-pyrrolone derivative 6	DMBW208	N. A.	N. A.	Patented	[6]
SGC-CBP30	DMTLRGZ	Discovery agent	N.A.	Investigative	[7]
I-CBP112	DMQX3W6	Discovery agent	N.A.	Investigative	[8]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem Biol. 2011 Apr 22;18(4):531-41.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Targeting the p300/CBP Axis in Lethal Prostate Cancer. Cancer Discov. 2021 May;11(5):1118-1137.
4	Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14309-14.
5	Clinical pipeline report, company report or official report of FORMA Therapeutics.
6	BET inhibitors in cancer therapeutics: a patent review.Expert Opin Ther Pat. 2016;26(4):505-22.
7	Bromodomains and their pharmacological inhibitors. ChemMedChem. 2014 Mar;9(3):438-64.
8	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2734).