Details of the Drug-Related molecule(s) Interaction Atlas

PNA-D-glucopyranoside Drug Info

P-nitrophenyl-alpha-D-glucopyranoside; A-D-glucopyranoside; p-Nitrophenyl-.beta.-galactoside; (2R,3S,4S,5S,6S)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol; 2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol; 2-(hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol; 4-Nitrophenyl-; 6-(hydroxymethyl)-2-(4-nitrophenoxy)-2H-3,4,5,6-tetrahydropyran-3,4,5-triol; p-NITROPHENYL-beta-D-GALACTOPYRANOSIDE; p-Nitrophenyl-alpha-D-glucopyranoside; p-Nitrophenyl-beta-D-glucopyranoside

Cross-matching ID

PubChem CID

259380

CAS Number

CAS 3150-24-1

TTD Drug ID

DMPUC8I

INTEDE Drug ID

DR2124

General Information of Drug (ID: DMPUC8I)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Metabolized By Beta-galactosidase (bgaB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Lactose	DMO4GPK	Discovery agent	N.A.	Phase 1	[3]
LS-71719	DM0TZPL	N. A.	N. A.	Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Beta-galactosidase (bgaB)	DEPR1Y7	BGAL_BIFAA	Substrate	[1]
Neutral alpha-glucosidase AB (GANAB)	DEMWKYT	GANAB_HUMAN	Substrate	[2]
Glucosidase II beta (PRKCSH)	DE073GW	GLU2B_HUMAN	Substrate	[2]
Beta-galactosidase (bgaB)	DEQB4LT	A0A2U1B4D0_9BACT	Substrate	[3]

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References

1	Beta-galactosidase from Bifidobacterium adolescentis DSM20083 prefers beta(1,4)-galactosides over lactose. Appl Microbiol Biotechnol. 2004 Dec;66(3):276-84.
2	The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo. Glycobiology. 2000 Aug;10(8):815-27.
3	Identification and characterization of a novel beta-galactosidase from Victivallis vadensis ATCC BAA-548, an anaerobic fecal bacterium. J Microbiol. 2012 Dec;50(6):1034-40.
4	Diverse galactooligosaccharides consumption by bifidobacteria: implications of beta-galactosidase--LacS operon. Biosci Biotechnol Biochem. 2015;79(4):664-72.