General Information of Drug (ID: DMPZTRC)

Drug Name
Ceftazidine Drug Info
Synonyms
Ceftazidine [INN]; Ceftazidine [USAN]; Ceftazidine [IBAN]; (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroxide
Cross-matching ID
PubChem CID
13505813
TTD Drug ID
DMPZTRC
INTEDE Drug ID
DR2679

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
Drug Status:
Approved Drug(s)
Drug(s) Metabolized By Beta-lactamase (blaB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imipenem DMI9FBP Bacteremia 1A73 Approved [2]
Ampicillin DMHWE7P Acute epiglottitis Approved [1]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [1]
Meropenem DM62UHC Bacterial infection 1A00-1C4Z Approved [2]
Carbapenem DMXZU73 N. A. N. A. Phase 4 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Beta-lactamase (blaB) Main DME DEBKS91 A0A1B1FBM9_ACIBA Substrate [1]

References

1 Drug-resistant genes carried by Acinetobacter baumanii isolated from patients with lower respiratory tract infection. Chin Med J (Engl). 2010 Sep;123(18):2571-5.
2 A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit. PLoS One. 2018 Dec 28;13(12):e0209367.
3 Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil. Rev Soc Bras Med Trop. 2019 Dec 20;53:e20190044.