Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQ6POC)

Drug Name

Pyridoxamine-5'-Phosphate Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Mycobacterium Biosynthetic alanine racemase (MycB alr)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cycloserine	DMT1I52	Bacterial infection	1A00-1C4Z	Approved	[1]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[1]
Lysine Nz-Carboxylic Acid	DMW1YK3	Discovery agent	N.A.	Investigative	[1]
Propionate	DM0O8N6	Discovery agent	N.A.	Investigative	[2]
Pyridoxyl-N,O-Cycloserylamide-5-Monophosphate	DM7AW0X	Discovery agent	N.A.	Investigative	[1]
N-(5'-Phosphopyridoxyl)-D-Alanine	DM3FCAI	Discovery agent	N.A.	Investigative	[1]
Pyridoxyl-Alanine-5-Phosphate	DMUVCWY	Discovery agent	N.A.	Investigative	[1]
Propanoic Acid	DM9TN2W	Discovery agent	N.A.	Investigative	[1]
3-fluorovinylglycine	DMECBLA	Discovery agent	N.A.	Investigative	[3]
------------------------------------------------------------------------------------


⏷ Show the Full List of 9 Drug(s)

Drug(s) Targeting Staphylococcus D-amino acid aminotransferase (Stap-coc dat)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------

Drug(s) Targeting Branched-chain-amino-acid transaminase 2 (BCAT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-ketoisovalerate	DMBZTS5	Discovery agent	N.A.	Investigative	[1]
N-[O-Phosphono-Pyridoxyl]-Isoleucine	DM6EICU	Discovery agent	N.A.	Investigative	[1]
N'-(phenylsulfonyl)benzofuran-2-carbohydrazide	DMJO3B1	Discovery agent	N.A.	Investigative	[4]
N'-(phenylsulfonyl)quinoline-6-carbohydrazide	DMQETUY	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Branched-chain-amino-acid transaminase 2 (BCAT2)	TTF9OQ6	BCAT2_HUMAN	Inhibitor	[1]
Mycobacterium Biosynthetic alanine racemase (MycB alr)	TT6TMZU	ALR_MYCSM	Inhibitor	[1]
Staphylococcus D-amino acid aminotransferase (Stap-coc dat)	TTN6GE9	DAAA_STAHA	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers. 2003 Oct;70(2):186-200.
3	Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem. 1991 Nov 15;266(32):21657-65.
4	The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40.