Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUELHN)

• Drug Name: Thiourea Drug Info
• Synonyms: 2-Thiopseudourea; 2-Thiourea; Carbamimidothioic acid; Caswell No. 855; Isothiourea; Pseudothiourea; Pseudourea, 2-thio-; RCRA waste no. U219;.beta.-Thiopseudourea; RCRA waste number U219; Sulfourea; Sulfouren; Sulourea; THIOUREA; Thiocarbamid; Thiocarbamide; Thiocarbonic acid diamide; Thioharnstoff; Thiokarbamid; Thiomocovina; Thiomocovina [Czech]; Thiurea; Thiuronium; Tsizp 34; Urea, 2-thio-; Urea, thio-; beta-Thiopseudourea; carbonothioic diamide; sulfocarbamide; thio-urea
• Cross-matching ID:
  PubChem CID: 2723790
  ChEBI ID: ChEBI:36946
  CAS Number: CAS 62-56-6
  TTD Drug ID: DMUELHN
  VARIDT Drug ID: DR00349

Molecule-Related Drug Atlas

Drug(s) Transported By Urea transporter 1 (SLC14A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
methylurea	DMAEQB6	Discovery agent	N.A.	Investigative	[5]

Drug(s) Affected By Carbonic anhydrase 1 (CA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[6]
Irbesartan	DMTP1DC	Diabetic kidney disease	GB61.Z	Approved	[7]
Voriconazole	DMAOL2S	Aspergillosis	1F20	Approved	[8]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[9]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[10]
Candesartan	DMRK8OT	Chronic heart failure	BD1Z	Approved	[7]
Indomethacin	DMSC4A7	Bursitis		Approved	[11]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[12]
Phenylephrine	DMZHUO5	Allergic rhinitis	CA08.0	Approved	[13]
GUAIACOL	DMN4E7T	N. A.	N. A.	Phase 3	[9]

Drug(s) Affected By Carbonic anhydrase 2 (CA2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetazolamide	DM1AF5U	Absence epilepsy		Approved	[11]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[14]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[15]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[16]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[17]
Methazolamide	DM7J2TA	Glaucoma/ocular hypertension	9C61	Approved	[18]
Topiramate	DM82Z30	Alcohol dependence	6C40.2	Approved	[19]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[20]
Voriconazole	DMAOL2S	Aspergillosis	1F20	Approved	[8]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]

Drug(s) Affected By Flavin-containing monooxygenase 3 (FMO3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[22]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[23]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[24]
Perazine	DM2AOTZ	Psychotic disorder	6A20-6A25	Approved	[25]
Almogran	DM7I64Z	Migraine	8A80	Approved	[26]
Ranitidine	DM0GUSX	Gastric ulcer	DA60	Approved	[27]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[28]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[29]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[30]

Drug(s) Affected By Flavin-containing monooxygenase 2 (FMO2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[31]
Trifluoperazine	DMKBYWI	Anxiety		Approved	[31]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[32]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[21]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[33]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[22]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[34]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[35]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[30]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[36]

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Urea transporter 1 (SLC14A1)	DTMF8LB	UT1_HUMAN	Substrate	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Carbonic anhydrase 1 (CA1)	OTNFBVVQ	CAH1_HUMAN	Gene/Protein Processing	[2]
Carbonic anhydrase 2 (CA2)	OTJRMUAG	CAH2_HUMAN	Gene/Protein Processing	[2]
Flavin-containing monooxygenase 2 (FMO2)	OTUJUL9S	FMO2_HUMAN	Regulation of Drug Effects	[3]
Flavin-containing monooxygenase 3 (FMO3)	OT1G2EV3	FMO3_HUMAN	Drug Response	[4]

References

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