Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMX0N9P)

Drug Name
Ginkgolide B (GKB) Drug Info
Synonyms SCHEMBL464783; MolPort-003-983-580; s1343; BN0224; NCGC00386140-01; BN 52021, 15291-77-7
Cross-matching ID
PubChem CID
17751009
CAS Number
CAS 15291-77-7
TTD Drug ID
DMX0N9P

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Translocator protein (TSPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [2]
Flunitrazepam DMGR5Z3 Insomnia 7A00-7A0Z Approved [3]
Oxazepam DMXNZM4 Alcohol withdrawal delirium Approved [4]
Midazolam DMXOELT Agitation 6A70.3 Approved [5]
Temazepam DM02A65 Insomnia 7A00-7A0Z Approved [5]
Flumazenil DMPCG2L Benzodiazepine overdose PC91 Approved [6]
Alprazolam DMC7XDN Anxiety Approved [3]
Clotiazepam DM59AZT Anxiety disorder 6B00-6B0Z Approved [7]
Quazepam DMY4D87 Insomnia 7A00-7A0Z Approved [5]
Eszopiclone DM8RZ9H Insomnia 7A00-7A0Z Approved [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Translocator protein (TSPO) TTPTXIN TSPO_HUMAN Suppressor [1]

References

1 Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells. Anticancer Res. 2000 Sep-Oct;20(5A):2835-47.
2 Translocator protein (18 kDa) mediates the pro-growth effects of diazepam on Ehrlich tumor cells in vivo. Eur J Pharmacol. 2010 Jan 25;626(2-3):131-8.
3 Comparison of five benzodiazepine-receptor agonists on buprenorphine-induced mu-opioid receptor regulation. J Pharmacol Sci. 2009 May;110(1):36-46.
4 Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats. Pharmacol Biochem Behav. 2008 Nov;91(1):181-9.
5 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2879).
7 Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurones. Br J Pharmacol. 1989 Nov;98(3):735-40.
8 New hypnotics: perspectives from sleep physiology. Vertex. 2007 Jul-Aug;18(74):294-9.