Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXV6YP)

Drug Name

Fus-1 tumor suppressor gene therapy Drug Info

Synonyms

Fus-1 tumor suppres; INGN-401; P53 bystander effector, Introgen; DOTAP:chol-TUSC2; FUS1-DOTAP:cholesterol; Fus-1 tumor suppressor gene therapy - nanoparticle formulation (cancer); Fus-1 tumor suppressor gene therapy-nanoparticle formulation (cancer), MD Anderson

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Phase 1/2	[1]

Cross-matching ID

TTD Drug ID: DMXV6YP

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Tumor suppressor candidate 2 (TUSC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CNVN-202	DMWZOD7	Non-small-cell lung cancer	2C25.Y	Phase 1/2	[3]
Quaratusugene ozeplasmid	DMZD7OA	Non-small-cell lung cancer	2C25.Y	Phase 1/2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tumor suppressor candidate 2 (TUSC2)	TTJ8O14	TUSC2_HUMAN	Suppressor	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018766)
2	INGN 201: Ad-p53, Ad5CMV-p53, adenoviral p53, p53 gene therapy--introgen, RPR/INGN 201. Drugs R D. 2007;8(3):176-87.
3	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018766)
4	Clinical pipeline report, company report or official report of Genprex.