Details of the Drug

General Information of Drug (ID: DMXV6YP)

Drug Name
Fus-1 tumor suppressor gene therapy
Synonyms
Fus-1 tumor suppres; INGN-401; P53 bystander effector, Introgen; DOTAP:chol-TUSC2; FUS1-DOTAP:cholesterol; Fus-1 tumor suppressor gene therapy - nanoparticle formulation (cancer); Fus-1 tumor suppressor gene therapy-nanoparticle formulation (cancer), MD Anderson
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 1/2 [1]
Cross-matching ID
TTD ID
D03YJW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tumor suppressor candidate 2 (TUSC2) TTJ8O14 TUSC2_HUMAN Suppressor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Non-small-cell lung cancer
ICD Disease Classification 2C25.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tumor suppressor candidate 2 (TUSC2) DTT TUSC2 3.62E-08 -0.16 -0.72
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018766)
2 INGN 201: Ad-p53, Ad5CMV-p53, adenoviral p53, p53 gene therapy--introgen, RPR/INGN 201. Drugs R D. 2007;8(3):176-87.