Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZCTGF)

• Drug Name: 3-(2-Benzylamino-ethoxy)-phenol Drug Info
• Synonyms: CHEMBL64508; 3-[2-(benzylamino)ethoxy]phenol; 3-(2-Benzylamino-ethoxy)-phenol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 11776546
  CAS Number: CAS 129689-29-8
  TTD Drug ID: DMZCTGF

Molecule-Related Drug Atlas

Drug(s) Targeting Dopamine D3 receptor (D3R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cariprazine	DMJYDVK	Bipolar disorder	6A60	Approved	[3]
Pramipexole	DMNMW9R	Parkinson disease	8A00.0	Approved	[4]
Ropinirole	DMA6S1D	Parkinson disease	8A00.0	Approved	[4]
CM-2395	DMASPWR	Schizophrenia	6A20	Phase 3	[5]
P2B-001	DM9PVHX	Parkinson disease	8A00.0	Phase 3	[6]
RP5063	DMKUE8O	Schizophrenia	6A20	Phase 2	[7]
ONC201	DMM5SCF	Endometrial cancer	2C76	Phase 2	[8]
TAK-906	DMBQD9H	Diabetic gastroparesis	DA41.00	Phase 2	[9]
GSK598809	DMGU05N	Drug abuse	6C4G.1Z	Phase 2	[10]
GSK618334	DMJPXZ4	Drug abuse	6C4G.1Z	Phase 1	[10]

Drug(s) Targeting Dopamine D4 receptor (D4R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[4]
Phenyltoloxamine	DMKAEQW	Allergy	4A80-4A85	Approved	[11]
CM-2395	DMASPWR	Schizophrenia	6A20	Phase 3	[5]
RP5063	DMKUE8O	Schizophrenia	6A20	Phase 2	[7]
L-745,870	DMTGR25	Psychotic disorder	6A20-6A25	Phase 2	[12]
NGD 94-1	DMM1Y8F	Schizophrenia	6A20	Phase 1	[13]
ABT-724	DMDQVY4	Erectile dysfunction	HA01.1	Discontinued in Phase 2	[14]
Lu-35138	DMQ7A35	Psychotic disorder	6A20-6A25	Discontinued in Phase 2	[15]
NGD-94-4	DMZ9WLO	Schizophrenia	6A20	Discontinued in Phase 1	[16]
PD-165167	DMD0GB4	Schizophrenia	6A20	Preclinical	[13]

Drug(s) Targeting Dopamine D2 receptor (D2R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dopamine	DMPGUCF	Acromegaly	5A60.0	Approved	[17]
Haloperidol	DM96SE0	Delirium		Approved	[18]
Perphenazine	DMA4MRX	Schizophrenia	6A20	Approved	[19]
Perazine	DM2AOTZ	Psychotic disorder	6A20-6A25	Approved	[20]
Domperidone	DMBDPY0	Gastrointestinal disease	DE2Z	Approved	[21]
Levodopa	DMN3E57	Parkinson disease	8A00.0	Approved	[22]
Quetiapine	DM1N62C	Anorexia nervosa cachexia	6B80	Approved	[23]
Pimozide	DMW83TP	Schizophrenia	6A20	Approved	[24]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[25]
Iloperidone	DM6AUFY	Schizophrenia	6A20	Approved	[26]

Drug(s) Targeting 5-HT 1A receptor (HTR1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Trazodone	DMK1GBJ	Depression	6A70-6A7Z	Approved	[4]
Buspirone	DMBS632	Anxiety disorder	6B00-6B0Z	Approved	[27]
OPC-34712	DMHG57U	Major depressive disorder	6A70.3	Approved	[28]
Vilazodone	DM4LECQ	Major depressive disorder	6A70.3	Approved	[29]
Flibanserin	DM70DTN	Depression	6A70-6A7Z	Approved	[3]
Gepirone	DMGX5Q0	Major depressive disorder	6A70.3	Approved	[30]
TERTATOLOL	DM2L3D5	Hypertension	BA00-BA04	Approved	[31]
Urapidil	DMD59GI	Hypertension	BA00-BA04	Approved	[32]
Treximet	DMU54QB	Migraine	8A80	Approved	[10]
CM-2395	DMASPWR	Schizophrenia	6A20	Phase 3	[5]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 1A receptor (HTR1A)	TTSQIFT	5HT1A_HUMAN	Inhibitor	[1]
Dopamine D2 receptor (D2R)	TTEX248	DRD2_HUMAN	Inhibitor	[2]
Dopamine D3 receptor (D3R)	TT4C8EA	DRD3_HUMAN	Inhibitor	[2]
Dopamine D4 receptor (D4R)	TTE0A2F	DRD4_HUMAN	Inhibitor	[2]

References

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