Details of the Drug Reposition

General Information of This Drug (ID: DMG281S)

Drug Name
Carboplatin   DMG281S
Synonyms
Azanide; Carbopaltin; Carboplatine; Carboplatino; Carboplatinum; Cbdca; Ercar; Paraplatin; Carboplatine [French]; Carboplatino [Spanish]; Carboplatinum [Latin]; C 2538; JM 8; Carboplatin (USAN); IUPAC: Azane; JM-8; Paraplatin (TN); Paraplatin, Carboplatin; Paraplatin-AQ; Cis-Diammine(cyclobutanedicarboxylato)platinumII; Platinum(+2) Cation; Carboplatin (JAN/USP/INN); Carboplatin [USAN:INN:BAN:JAN]; Cyclobutane-1,1-dicarboxylate; Cyclobutane-1,1-dicarboxylic acid; Diammine-1,1-cyclobutane dicarboxylate platinum II; Cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II); Cis-Diammine(1,1-cyclobutanedicarboxylato) platinum; Cis-Diammine(1,1-cyclobutanedicarboxylato)platinum; Cis-Diammine[1,1-cyclobutane-dicarboxylato] platinum; Diammine(1,1-cyclobutanedicarboxylato)platinum (II); Platinum, {diammine[1,1-cyclobut; Cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II); Cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II); Cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II); Platinum(II), (1, 1-cyclobutanedicar; Diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum; Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum; Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2); (SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum; 1,1-Cyclobutanedicarboxylate diammine platinum (II); 1,1-Cyclobutanedicarboxylate diammine platinum(II)
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
12 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ovarian serous cystadenocarcinoma DISMYAWR N.A. Approved [1]
Ovarian neoplasm DISEAFTY N.A. Approved [1]
Ovarian disorder DISHZX9D N.A. Approved [1]
Lung adenocarcinoma DISD51WR N.A. Approved [1]
Fallopian tube neoplasm DISHMMF2 N.A. Approved [1]
Carcinoma DISH9F1N 2A00-2F9Z Approved [1]
Epithelial ovarian cancer DIS56MH2 2B5D Approved [1]
Gastroesophageal junction adenocarcinoma DISCVPML 2B71 Approved [1]
Cholangiocarcinoma DIS71F6X 2C12.10 Approved [1]
Small-cell lung cancer DISK3LZD 2C25.Y Approved [1]
Cutaneous melanoma DIS3MMH9 2C30 Approved [1]
Adenocarcinoma DIS3IHTY 2D40 Approved [1]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 Indications(s)
1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ovarian cancer DISZJHAP 2C73 Withdrawn [2]
------------------------------------------------------------------------------------
2 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Hepatobiliary neoplasm DISSXKSB N.A. Discontinued in Phase 3 [3]
Esophageal adenocarcinoma DISODWFP N.A. Discontinued in Phase 3 [4]
------------------------------------------------------------------------------------
5 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Cancer of unknown primary site DISSA12E N.A. Discontinued in Phase 2 [5]
Neoplasm of esophagus DISOLKAQ N.A. Discontinued in Phase 2 [6]
Thyroid gland undifferentiated (anaplastic) carcinoma DISYBB1W N.A. Discontinued in Phase 2 [7]
Anaplastic astrocytoma DISSBE0K 2A00.0 Discontinued in Phase 2 [8]
Non-hodgkin lymphoma DISS2Y8A 2B33.5 Discontinued in Phase 2 [9]
------------------------------------------------------------------------------------
2 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Lung large cell carcinoma DISUG64F N.A. Investigative [1]
Neuroblastoma DISVZBI4 2D11.2 Investigative [1]
------------------------------------------------------------------------------------

References

1 Carboplatin FDA Label
2 ClinicalTrials.gov (NCT00000372) Glycine and D-Cycloserine in Schizophrenia
3 Memantine for the Prevention of Cognitive Dysfunction and Negative Symptoms in Patients With Acute Schizophrenia
4 Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
5 A Phase II Study of Pemetrexed and Carboplatin in the Treatment of Esophageal Cancer
6 Erlotinib and Avastin in Patients With Cancer of the Esophagus or Gastroesophageal Junction
7 ClinicalTrials.gov (NCT01652014) Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies
8 Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer
9 Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer