Details of the Drug Reposition

General Information of This Drug (ID: DMPZI3Q)

Drug Name
Ketoconazole   DMPZI3Q
Synonyms
KCZ; KTZ; K 1003; R 41400; R41400; KS-1205; KW-1414; Perkhotal (TN); R 41,400; R-41400; R41,400; Ketoconazole [USAN:INN:BAN:JAN]; Nizoral, Extina, Xolegel, Kuric, Ketoconazole; Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; Cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; CIS-1-ACETYL-4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE; (+-)-cis-1-Acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine; (+/-)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine; (+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone; 1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
Therapeutic Class
Antifungal Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
11 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Prostate adenocarcinoma DISBZYU8 N.A. Approved [1]
Pityriasis simplex DIS1K9V6 N.A. Approved [1]
Paracoccidioidomycosis DIS88F55 N.A. Approved [1]
Histoplasmosis DISGTF4W N.A. Approved [1]
Chromomycosis DIS4IXDI N.A. Approved [1]
Blastomycosis DISJ3EYJ 1F22 Approved [1]
Oral candidiasis DISAVKAH 1F23.0 Approved [1]
Coccidioidomycosis DISJ5NW7 1F25 Approved [1]
Tinea cruris DIS5JC14 1F28.3 Approved [1]
Tinea versicolor DIS5VG35 1F2D.0 Approved [1]
Mycoses DIS9K7PB 1F2Z Approved [1]
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⏷ Show the Full List of 11 Indications(s)
2 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ovarian granulosa cell tumor DISRVQAA N.A. Discontinued in Phase 3 [2]
Seborrhoeic dermatitis DISNWVJU EA81 Discontinued in Phase 3 [3]
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1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Adrenal gland hyperfunction DISPP4ZK N.A. Discontinued in Phase 2 [4]
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References

1 Ketoconazole FDA Label
2 Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML
3 A Study of the Efficacy and Safety of Topiramate in Obese, Type 2 Diabetic Patients Inadequately Controlled on Sulfonylurea Therapy
4 Ranolazine Cardioprotection in PCI