Details of the Drug Reposition

General Information of This Drug (ID: DMTP2NJ)

Drug Name
Desonide   DMTP2NJ
Synonyms
Apolar; DesOwen; Desilux; Desonate; Desonida; Desonidum; Flusemidon; Hamiltoderm; Locapred; Prednacinolone; Prenacid; Reticus; Sterax; Steroderm; Topifug; Tridesilon; Tridesonit; Verdeso; Zotinar; Desfluorotriamcinolone acetonide; D 2083; D-2083; Desonida [INN-Spanish]; Desonidum [INN-Latin]; Desowen (TN); Verdeso (TN);Verdeso Foam (TN); Desonide (USAN/INN); Desonide [USAN:INN:BAN]; Locapred, Topifug, Tridesilon, Desonide; (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; 11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17-isopropylidenedioxypregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione; 16-alpha-Hydroxyprednisole-16,17-acetonide; 16alpha,17alpha-isopropylidenedioxyprednisolone; 16alpha-hydroxyprednisole-16,17-acetonide; 16alpha-hydroxyprednisolone-16alpha,17-acetonide
Therapeutic Class
Antiinflammatory Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
5 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Primary cutaneous T-cell lymphoma DIS35WVW N.A. Approved [1]
Granuloma annulare DISMOUMI N.A. Approved [1]
Exanthem DISAFOQN N.A. Approved [1]
Allergic rhinitis DIS3U9HN CA08.0 Approved [1]
Crohn disease DIS2C5Q8 DD70 Approved [1]
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2 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Otitis externa DISYCORK AA00-AA13 Discontinued in Phase 2 [2]
Atopic dermatitis DISTCP41 EA80 Discontinued in Phase 2 [3]
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2 Discontinued in Phase 1 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Seborrhoeic dermatitis DISNWVJU EA81 Discontinued in Phase 1 [4]
Contact dermatitis DISQ3AU0 EK0Z Discontinued in Phase 1 [5]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Asthma DISW9QNS CA23 Investigative [1]
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References

1 Desonide FDA Label
2 Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma
3 ClinicalTrials.gov (NCT00033371) Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis
4 Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia
5 Trial of Cooling for Patients With Excel Cryo Cooling System in Intracerebral Hemorrhage (ICH)