Details of the Drug

General Information of Drug (ID: DM0YOXQ)

Drug Name
SB-431542
Synonyms
301836-41-9; SB-431542; SB 431542; 4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide; SB431542; UNII-E1557V1V0N; CHEMBL440084; E1557V1V0N; 4-[4-(1,3-BENZODIOXOL-5-YL)-5-(2-PYRIDINYL)-1H-IMIDAZOL-2-YL]BENZAMIDE; 4-(4-(1,3-Benzodioxole-5-yl)-5-(2-pyridyl)-1H-imidazole-2-yl)benzamide; SB 431542 hydrate; C22H16N4O3; 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide; 4-(4-Benzo[1,3]dioxol-5-yl-5-pyridin-2-yl-1H-imidazol-2-yl)-benzamide
Indication
Disease Entry ICD 11 Status REF
Pulmonary fibrosis CB03.4 Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 384.4
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C22H16N4O3
IUPAC Name
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Canonical SMILES
C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChI
InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChIKey
FHYUGAJXYORMHI-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
4521392
ChEBI ID
CHEBI:91108
CAS Number
301836-41-9
TTD ID
D0C7WP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TGF-beta receptor type I (TGFBR1) TTP4520 TGFR1_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) OTNAZVKB 3BHS1_HUMAN Gene/Protein Processing [3]
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) OT7RJON4 HCD2_HUMAN Gene/Protein Processing [3]
3-ketodihydrosphingosine reductase (KDSR) OTCIES3H KDSR_HUMAN Gene/Protein Processing [3]
Adipocyte plasma membrane-associated protein (APMAP) OT1P2GJA APMAP_HUMAN Gene/Protein Processing [3]
AP-1 complex subunit beta-1 (AP1B1) OTY0K84R AP1B1_HUMAN Gene/Protein Processing [3]
AP-2 complex subunit alpha-1 (AP2A1) OTEFZB21 AP2A1_HUMAN Gene/Protein Processing [3]
AP-2 complex subunit alpha-2 (AP2A2) OTD1UGUN AP2A2_HUMAN Gene/Protein Processing [3]
Band 4.1-like protein 5 (EPB41L5) OTPPQPLU E41L5_HUMAN Gene/Protein Processing [3]
Basal cell adhesion molecule (BCAM) OTHZOPSD BCAM_HUMAN Gene/Protein Processing [3]
Basigin (BSG) OTD0CVEC BASI_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Pulmonary fibrosis
ICD Disease Classification CB03.4
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
TGF-beta receptor type I (TGFBR1) DTT TGFBR1 2.62E-01 0.27 1.01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 136 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 5.9404 7.8857 5.0357 4.4451
MEC1 CTRP2 5.9987 6.9761 5.5399 2.2102
JM1 CTRP2 6.0317 7.1354 5.4883 2.3622
EoL-1 CTRP2 4.2497 7.1039 3.721 13.8953
NU-DUL-1 CTRP2 4.4288 6.1834 4.2414 11.4239
KMS-20 CTRP2 5.0079 6.8115 4.6399 8.2673
REC-1 CTRP2 5.0972 9.3121 3.5668 12.3908
EM-2 CTRP2 5.1127 6.1849 4.986 6.6565
NU-DHL-1 CTRP2 5.141 8.3029 4.0958 10.1184
LP-1 CTRP2 5.3247 8.8391 4.0098 10.0493
RPMI-8226 CTRP2 5.3827 7.0912 4.9027 6.2499
Peer CTRP2 5.4256 6.7061 5.1193 5.2753
Daudi CTRP2 5.4401 10.0969 3.4949 11.9271
SU-DHL-10 CTRP2 5.5335 8.4828 4.377 8.0609
MV4-11 CTRP2 5.5375 6.6096 5.2764 4.3615
HuT 78 CTRP2 5.546 8.723 4.27 8.4789
GDM-1 CTRP2 5.557 6.555 5.3203 4.1373
BL-70 CTRP2 5.5668 6.1471 5.4919 3.4491
KM-H2 CTRP2 5.5782 7.8042 4.7512 6.4081
L-428 CTRP2 5.5922 10.1015 3.6277 11.055
Ki-JK CTRP2 5.6475 8.5596 4.4425 7.5407
SUP-HD1 CTRP2 5.6657 8.1108 4.6808 6.507
MOLT-16 CTRP2 5.671 6.5141 5.455 3.3071
A4/Fukuda CTRP2 5.676 6.3767 5.5202 3.0361
LAMA-84 CTRP2 5.6763 7.1651 5.1539 4.52
Karpas-299 CTRP2 5.7079 7.2885 5.1237 4.5724
ME1 CTRP2 5.7187 6.3378 5.5811 2.6838
ST486 CTRP2 5.7296 7.2449 5.1652 4.3517
GA-10 CTRP2 5.7297 6.325 5.598 2.5882
L-540 CTRP2 5.7515 7.1358 5.2388 3.9975
NALM-6 CTRP2 5.7629 9.0155 4.3182 7.8174
NCO2 CTRP2 5.7709 7.8481 4.9055 5.3425
KMS-34 CTRP2 5.7717 7.7398 4.9599 5.1135
EB1 CTRP2 5.7823 6.8882 5.3882 3.3097
JURL-MK1 CTRP2 5.8172 8.0969 4.8231 5.5894
NOMO-1 CTRP2 5.8211 6.5281 5.5982 2.3561
OCI-AML-2 CTRP2 5.825 6.6999 5.5197 2.6688
SU-DHL-8 CTRP2 5.8252 8.0573 4.8499 5.4606
RPMI-8402 CTRP2 5.8317 7.7465 5.0102 4.776
HDLM-2 CTRP2 5.8455 8.395 4.6995 6.0491
DB CTRP2 5.8457 6.8441 5.4689 2.832
MOLP-8 CTRP2 5.8559 6.791 5.5043 2.6623
Ri-1 CTRP2 5.8718 7.267 5.284 3.5458
RS4;11 CTRP2 5.872 8.6047 4.6179 6.337
BV-173 CTRP2 5.8724 7.8788 4.9802 4.8167
JJN-3 CTRP2 5.8744 7.9603 4.9413 4.9757
Ku812 CTRP2 5.8773 8.6802 4.5847 6.4657
AMO1 CTRP2 5.878 6.7165 5.5613 2.3765
SU-DHL-6 CTRP2 5.9174 6.8941 5.5096 2.5059
OCI-M1 CTRP2 5.9411 6.6115 5.6708 1.7818
KMS-11 CTRP2 5.9586 7.4424 5.2726 3.4136
Reh CTRP2 5.9598 6.7291 5.6292 1.9155
KMS-12-BM CTRP2 5.9754 6.8785 5.5685 2.1374
NB4 CTRP2 5.9783 6.8481 5.5862 2.0576
PF-382 CTRP2 5.979 7.5153 5.2538 3.4516
Raji CTRP2 5.9807 6.7763 5.6241 1.8938
CML-T1 CTRP2 5.9941 7.2157 5.4164 2.7385
Jurkat CTRP2 5.9985 7.5856 5.2353 3.4906
Kasumi-2 CTRP2 6.001 8.249 4.9057 4.8709
Hs 611.T CTRP2 6.0081 9.9924 4.0401 8.4919
MOLT-13 CTRP2 6.0239 7.2184 5.4402 2.5795
MC116 CTRP2 6.0242 6.7418 5.6787 1.5763
MOLM-16 CTRP2 6.0251 7.4457 5.3276 3.0505
Mino CTRP2 6.0312 6.8996 5.6058 1.8693
P12-Ichikawa CTRP2 6.0391 7.4343 5.345 2.9501
F-36P CTRP2 6.0434 10.1075 4.012 8.541
KMS-18 CTRP2 6.0436 7.7492 5.1913 3.5875
KE-97 CTRP2 6.0615 7.1014 5.5301 2.1292
MM1.S CTRP2 6.088 7.1413 5.5319 2.0714
RL CTRP2 6.092 7.1288 5.5414 2.0243
KMS-27 CTRP2 6.0942 7.6309 5.2923 3.0665
SUP-B15 CTRP2 6.1016 7.711 5.2583 3.1955
KCL-22 CTRP2 6.1288 8.2867 4.9928 4.26
HD-MY-Z CTRP2 6.1314 7.0415 5.6164 1.6378
M-07e CTRP2 6.1413 13.5673 2.3634 15.0303
HL-60 CTRP2 6.1569 7.1151 5.5996 1.6633
K-562 CTRP2 6.173 7.6999 5.3212 2.8003
U-937 CTRP2 6.1743 7.215 5.5635 1.784
SET-2 CTRP2 6.1801 7.2096 5.5707 1.7443
MOTN-1 CTRP2 6.2168 7.7501 5.3306 2.6836
DND-41 CTRP2 6.2178 7.8272 5.293 2.839
PL21 CTRP2 6.2207 8.4644 4.978 4.1535
SU-DHL-4 CTRP2 6.2234 7.5752 5.4225 2.2882
SEM CTRP2 6.2393 7.2441 5.5982 1.531
KE-37 CTRP2 6.2488 7.7901 5.3355 2.608
JeKo-1 CTRP2 6.2612 8.0164 5.2327 3.0156
AML-193 CTRP2 6.2638 7.5441 5.4686 2.0285
MOLM-6 CTRP2 6.2641 7.7396 5.3722 2.4288
L-363 CTRP2 6.2778 8.7615 4.8751 4.4826
P31/FUJ CTRP2 6.2816 7.7051 5.4025 2.2734
OCI-AML-3 CTRP2 6.303 7.47 5.534 1.6949
Kasumi-1 CTRP2 6.3067 8.0032 5.2741 2.7656
RCH-ACV CTRP2 6.3305 7.9581 5.3142 2.5593
NCI-H929 CTRP2 6.335 7.6146 5.4863 1.8408
MOLM-13 CTRP2 6.3375 8.3439 5.1288 3.3185
Granta-519 CTRP2 6.3753 8.8297 4.917 4.1373
DEL CTRP2 6.388 7.5019 5.5783 1.3868
SU-DHL-1 CTRP2 6.3891 8.1883 5.2444 2.7532
TALL-1 [Human adult T-ALL] CTRP2 6.3911 11.9043 3.3981 10.4351
KMS-21-BM CTRP2 6.4056 8.4575 5.124 3.2249
SUP-T1 CTRP2 6.4105 10.5999 4.0641 7.6398
KMS-26 CTRP2 6.4137 8.0508 5.3299 2.3613
HPB-ALL CTRP2 6.4305 8.8476 4.9501 3.9063
SK-MM-2 CTRP2 6.4418 8.1771 5.2884 2.488
HT CTRP2 6.4443 7.5647 5.5861 1.2775
SKM-1 CTRP2 6.4832 8.9898 4.9194 3.9463
SIG-M5 CTRP2 6.5005 8.8312 5.0104 3.5411
MOLP-2 CTRP2 6.5247 8.6703 5.107 3.1042
HEL 92.1.7 CTRP2 6.5312 8.9371 4.981 3.6135
TF-1 CTRP2 6.5342 7.8625 5.504 1.4819
SR CTRP2 6.5372 7.8389 5.5171 1.4264
Karpas-422 CTRP2 6.5376 7.9673 5.4564 1.6661
JVM-2 CTRP2 6.6156 8.5814 5.2146 2.5274
KO52 CTRP2 6.6312 8.0933 5.458 1.5358
HEL CTRP2 6.6401 8.4023 5.3173 2.0795
EHEB CTRP2 6.6748 9.4491 4.8345 3.9902
OCI-AML-5 CTRP2 6.6974 8.8582 5.1375 2.7209
THP-1 CTRP2 6.8892 8.5183 5.4204 1.3714
CMK CTRP2 6.9604 9.2546 5.1234 2.419
RPMI-6666 CTRP2 7.0133 11.3392 4.1546 6.2533
Ci-1 CTRP2 7.0733 7.9716 5.7448 0.2114
MHH-CALL-3 CTRP2 7.1377 9.4302 5.1526 2.0896
OCI-Ly19 CTRP2 7.14 9.7464 5.0073 2.6426
P3HR-1 CTRP2 7.1889 10.6974 4.5888 4.2298
KYO-1 CTRP2 7.2603 9.0045 5.4127 1.035
EJM CTRP2 7.5352 19.2571 0.6356 18.4386
U266B1 CTRP2 7.6025 12.7692 3.8752 6.4996
Mono-Mac-1 CTRP2 7.7138 11.9447 4.3424 4.4982
OCI-Ly3 CTRP2 7.8175 23.9927 -1.4983 23.6665
MJ CTRP2 7.8744 10.7172 4.9992 1.8754
JVM-3 CTRP2 8.0201 9.7726 5.4587 0.4286
SUP-T11 CTRP2 8.0949 9.4988 5.5887 0.1685
KHM-1B CTRP2 8.1478 9.7567 5.5165 0.2683
KMM-1 CTRP2 8.1738 10.1 5.3989 0.4933
MHH-CALL-4 CTRP2 8.7376 10.3711 5.5192 0.1306
L-1236 CTRP2 8.824 11.0585 5.307 0.4267
⏷ Show the Full List of 136 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 6.7697 10.387 4.4439 5.4496
TE8 CTRP2 7.8215 22.6497 -0.8277 22.0433
OE21 CTRP2 5.8884 7.562 5.152 4.0637
KYSE-30 CTRP2 6.0717 19.9681 -0.8947 25.3769
TE-5 CTRP2 6.2241 8.3728 5.0263 3.9448
KYSE-520 CTRP2 6.2707 7.8967 5.2995 2.7207
KYSE-410 CTRP2 6.3652 15.9269 1.3679 18.2035
OE33 CTRP2 6.4823 10.6585 4.0914 7.3983
TE-1 CTRP2 6.5228 8.2567 5.3071 2.2885
TE-6 CTRP2 6.5991 10.4843 3.4853 4.3802
TE-10 CTRP2 6.6005 10.5498 4.2367 6.5885
KYSE-140 CTRP2 6.6286 16.6871 1.2017 18.2609
TE-9 CTRP2 6.8385 9.5164 4.9173 3.4065
TE-4 CTRP2 6.8582 11.8966 3.7657 8.1021
COLO 680N CTRP2 6.8744 8.3452 5.49 1.1334
EC-GI-10 CTRP2 6.9183 8.7997 5.309 1.7558
KYSE-450 CTRP2 7.4126 10.4235 4.8629 2.8636
TE-11 CTRP2 7.4698 15.3165 2.536 11.9761
KYSE-180 CTRP2 7.4915 15.8215 2.3032 12.8171
TE-14 CTRP2 7.9095 9.8388 5.3848 0.6605
OE19 CTRP2 8.1811 13.5605 3.8829 5.6794
KYSE-70 CTRP2 8.4103 10.0449 5.5134 0.2019
KYSE-150 CTRP2 10.9398 19.5976 2.7819 6.4907
KYSE-510 CTRP2 12.27 26.1823 0.5698 11.9567
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.372 8.6931 4.9822 3.8713
Capan-2 CTRP2 5.3414 14.2523 1.3408 20.3889
Panc 10.05 CTRP2 5.6716 7.6186 4.9285 5.4636
Panc 08.13 CTRP2 5.708 7.6587 4.9422 5.3261
SUIT-2 CTRP2 5.8036 7.2057 5.2526 3.8239
Panc 03.27 CTRP2 5.8208 7.4415 5.1518 4.207
AsPC-1 CTRP2 5.8354 8.7385 4.5194 6.8252
PaTu 8988s CTRP2 5.9639 7.1873 5.4046 2.8489
PaTu 8902 CTRP2 6.0023 6.8491 5.6064 1.9239
SU.86.86 CTRP2 6.1527 7.4548 5.4273 2.3922
MIA PaCa-2 CTRP2 6.1606 7.1077 5.6062 1.6296
DAN-G CTRP2 6.1784 7.3247 5.5122 1.9913
KP-3 CTRP2 6.2785 8.9104 4.8015 4.7895
Hs 766T CTRP2 6.2806 8.1225 5.1951 3.1393
SNU-213 CTRP2 6.3252 8.7806 4.9027 4.2837
Panc 02.03 CTRP2 6.364 7.8066 5.4134 2.0955
PSN1 CTRP2 6.6379 9.5242 4.7709 4.3103
L3.3 CTRP2 6.6476 8.196 5.4202 1.6625
CFPAC-1 CTRP2 6.6547 8.9761 5.0508 3.1354
SW1990 CTRP2 6.7167 12.0324 3.5906 9.0628
BxPC-3 CTRP2 6.8487 10.1498 4.6173 4.6127
KP-2 CTRP2 7.0511 8.8477 5.3662 1.3955
HuP-T3 CTRP2 7.0583 9.038 5.2844 1.6871
PK-45H CTRP2 7.4695 11.5765 4.3569 4.7663
PK-59 CTRP2 7.5645 10.9616 4.7076 3.2732
KP-4 CTRP2 7.5655 8.9644 5.5746 0.3721
TCC-Pan2 CTRP2 7.682 10.8253 4.8415 2.634
YAPC CTRP2 7.7705 9.7268 5.3654 0.7974
PaTu 8988t CTRP2 7.8542 8.9595 5.6889 0.0905
Panc 05.04 CTRP2 8.0625 9.2986 5.6467 0.1023
QGP-1 CTRP2 8.1202 9.7849 5.4952 0.3159
HPAC CTRP2 8.1388 9.9599 5.4374 0.4244
SNU-410 CTRP2 8.3182 10.4703 5.3186 0.6108
HuP-T4 CTRP2 9.0198 22.7172 0.0389 17.7906
HPAF-II CTRP2 9.1512 11.0771 5.4243 0.1662
Panc 04.03 CTRP2 9.3316 16.1798 3.3836 6.1469
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.6432 11.8097 1.9244 19.8944
Mel JuSo CTRP2 5.9961 6.7351 5.658 1.7196
IGR-37 CTRP2 6.167 7.6391 5.3468 2.7039
Mel Ho CTRP2 6.2288 7.4226 5.5023 1.9468
LOX-IMVI CTRP2 6.3189 7.5055 5.5281 1.6943
Hs 944.T CTRP2 6.3401 7.7898 5.4042 2.1711
IPC-298 CTRP2 6.3885 7.7786 5.4446 1.9294
WM1799 CTRP2 6.4243 7.6777 5.5186 1.5756
A-375 CTRP2 6.4343 7.8458 5.4443 1.8617
WM88 CTRP2 6.4562 7.8464 5.4592 1.7693
HMCB CTRP2 6.4907 7.407 5.6893 0.8193
WM115 CTRP2 6.5104 8.2669 5.2935 2.3625
UACC-257 CTRP2 6.5531 8.1811 5.3645 2.0123
COLO 800 CTRP2 6.5767 8.047 5.4444 1.6608
SK-MEL-30 CTRP2 6.6819 7.9046 5.5766 1.0235
WT2-iPS CTRP2 6.7207 9.2251 4.9763 3.3401
Hs 839.T CTRP2 6.8223 7.9156 5.65 0.6302
Hs 895.T CTRP2 6.8284 8.1337 5.5581 0.9372
MeWo CTRP2 6.8552 9.1504 5.104 2.6343
WM793 CTRP2 6.8786 8.4724 5.435 1.3294
SK-MEL-5 CTRP2 6.9098 8.6166 5.3879 1.469
IGR-1 CTRP2 6.9482 16.9282 1.3361 17.2166
WM983B CTRP2 6.9855 9.4291 5.0574 2.6451
Hs 940.T CTRP2 6.9981 10.525 4.5405 4.7001
IGR-39 CTRP2 7.0009 8.5788 5.4576 1.1207
RVH-421 CTRP2 7.0499 10.8603 4.4143 5.1364
SK-MEL-3 CTRP2 7.0576 8.6898 5.4402 1.1265
CJM [Human melanoma] CTRP2 7.0745 9.5836 5.0419 2.5909
HT-144 CTRP2 7.0784 8.832 5.3888 1.2866
K029AX CTRP2 7.0786 9.7109 4.9847 2.8089
A2058 CTRP2 7.0883 8.3714 5.5927 0.602
COLO 792 CTRP2 7.1073 16.1025 1.8714 15.0608
RPMI-7951 CTRP2 7.1153 8.6965 5.4686 0.9762
UACC-62 CTRP2 7.1464 8.6651 5.4985 0.8511
SK-MEL-31 CTRP2 7.1899 9.2766 5.2537 1.6567
SK-MEL-28 CTRP2 7.2102 8.0286 5.7782 0.1062
Hs 934.T CTRP2 7.3235 8.6467 5.592 0.4531
A101D CTRP2 7.418 10.156 4.9892 2.3807
Malme-3M CTRP2 7.5745 13.2074 3.644 7.4641
SK-MEL-1 CTRP2 7.6325 8.9766 5.598 0.293
MDA-MB-435S CTRP2 7.6616 9.2317 5.5129 0.4711
WM266-4 CTRP2 7.8411 8.7503 5.7549 0.0356
Hs 294T CTRP2 7.842 9.2861 5.5678 0.2753
Hs 936.T CTRP2 7.8838 9.0517 5.6677 0.1096
COLO 829 CTRP2 8.005 9.5559 5.5336 0.2836
G-361 CTRP2 8.1466 9.4316 5.6311 0.1056
Hs 852.T CTRP2 8.2976 9.9116 5.5183 0.2226
SK-MEL-2 CTRP2 10.2268 24.9473 -0.1892 16.6715
Hs 688(A).T CTRP2 13.6919 35.0378 -2.6813 18.2803
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.3157 8.5786 4.9957 3.9112
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NH-6 CTRP2 6.231 8.0573 5.1889 3.2516
Kelly CTRP2 6.3582 11.2516 3.6975 9.2605
KP-N-SI9s CTRP2 6.4012 7.6457 5.5181 1.611
SK-N-SH CTRP2 6.6655 9.3142 4.8938 3.7613
MHH-NB-11 CTRP2 6.6998 8.874 5.1315 2.7412
NB1 CTRP2 6.7004 7.8634 5.606 0.8967
SK-N-DZ CTRP2 6.7179 8.306 5.4135 1.5989
SiMa CTRP2 7.4485 9.9426 5.1038 1.9271
SK-N-BE(2) CTRP2 7.6815 10.2488 5.0988 1.714
CHP-126 CTRP2 8.4891 21.3175 0.3371 17.7548
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 5.9117 7.7424 5.0824 4.3072
SNU-478 CTRP2 6.21 8.265 5.0689 3.7918
SNU-308 CTRP2 6.2489 8.3948 5.035 3.8645
SNU-1196 CTRP2 6.6231 7.8917 5.5469 1.2024
SNU-869 CTRP2 6.9793 14.2056 2.7144 12.1224
HuH-28 CTRP2 8.0378 9.5952 5.5321 0.2754
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 5.9875 7.4849 5.2762 3.3406
SK-N-MC CTRP2 6.1035 7.1539 5.5381 2.0168
SK-ES-1 CTRP2 6.2014 7.8728 5.2575 3.0166
CAL-78 CTRP2 6.2405 7.6039 5.4214 2.2637
TC71 CTRP2 6.3614 7.6601 5.4831 1.8132
MHH-ES-1 CTRP2 6.4292 8.8504 4.9478 3.9181
SJSA-1 CTRP2 6.5028 11.1713 3.8522 8.3574
SaOS-2 CTRP2 6.522 9.6332 4.6308 5.0814
Hs 888.T CTRP2 6.5641 8.2851 5.322 2.1678
HOS CTRP2 6.8307 8.764 5.2707 2.0107
SW1353 CTRP2 6.9929 8.4605 5.5052 0.9634
Hs 822.T CTRP2 7.0177 7.8624 5.7629 0.196
G-292 clone A141B1 CTRP2 7.7313 9.5491 5.4188 0.6744
U2OS CTRP2 7.8457 10.1043 5.2464 1.0949
MG-63 CTRP2 8.1371 15.0914 3.1238 8.6818
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 5.382 6.6454 5.1003 5.4651
AU565 CTRP2 5.4928 7.8215 4.6628 6.9678
CAL-85-1 CTRP2 5.9479 7.6075 5.181 3.8198
ZR-75-30 CTRP2 5.9554 8.7402 4.6217 6.1541
HCC202 CTRP2 6.0677 9.087 4.5424 6.2683
HCC1143 CTRP2 6.1001 9.8189 4.2033 7.6303
HCC2218 CTRP2 6.1937 13.4865 2.447 14.607
HCC1419 CTRP2 6.2885 22.748 -2.1049 27.6643
BT-474 CTRP2 6.3319 7.7093 5.4377 2.0461
CAL-51 CTRP2 6.3347 7.7085 5.4401 2.0315
SK-BR-3 CTRP2 6.3932 8.1468 5.2678 2.6496
CAL-120 CTRP2 6.4284 7.7342 5.4941 1.6685
HCC1395 CTRP2 6.4547 9.2134 4.7875 4.5423
MDA-MB-361 CTRP2 6.4614 8.7954 4.9991 3.6515
BT-20 CTRP2 6.496 8.1135 5.3577 2.1224
HMC-1-8 CTRP2 6.5456 7.7403 5.5689 1.2132
HCC1428 CTRP2 6.5598 8.3144 5.3049 2.2433
HCC1500 CTRP2 6.5624 11.2368 3.8663 8.1936
MDA-MB-468 CTRP2 6.6534 12.1318 3.4922 9.5771
JIMT-1 CTRP2 6.7671 9.6216 4.8164 3.9225
MDA-MB-231 CTRP2 6.7851 9.5701 4.8541 3.7415
CAL-148 CTRP2 6.8506 13.294 3.0676 10.9518
HCC38 CTRP2 7.1642 9.264 5.2443 1.7183
BT-549 CTRP2 7.208 10.2881 4.7962 3.3796
HCC1937 CTRP2 7.3887 10.0422 5.0237 2.2854
T-47D CTRP2 7.4815 15.1688 2.6175 11.6462
Hs 578Bst CTRP2 7.5848 17.5745 1.5074 15.5116
EFM-192A CTRP2 7.6372 9.8412 5.2516 1.2425
CAMA-1 CTRP2 7.7647 9.5567 5.4311 0.6221
MDA-MB-157 CTRP2 7.7749 9.8089 5.3339 0.8847
HCC1954 CTRP2 7.7922 10.3509 5.1141 1.5614
MCF-7 CTRP2 7.8841 13.9505 3.4996 7.5828
MDA-MB-453 CTRP2 7.9047 22.0107 -0.4464 20.9138
ZR-75-1 CTRP2 8.0999 9.3437 5.6446 0.0986
Hs 578T CTRP2 8.2627 21.6062 0.026 19.0212
HDQ-P1 CTRP2 8.3676 10.1323 5.4658 0.2886
HCC1806 CTRP2 8.7182 10.2771 5.5445 0.1079
KPL-1 CTRP2 9.0408 21.9813 0.4142 16.6689
BT 416 CTRP2 5.8903 12.8701 2.5023 14.9925
BT 498 CTRP2 6.4415 12.1642 3.3088 10.7081
BT147 CTRP2 6.4428 7.7635 5.49 1.6644
BT 428 CTRP2 6.615 8.6406 5.1856 2.6458
BT 328 CTRP2 6.6266 7.7649 5.6073 0.9715
BT 286 CTRP2 6.6743 8.2104 5.4306 1.5875
BT 216 CTRP2 6.687 8.2486 5.4207 1.6097
BT164 CTRP2 6.7609 9.5398 4.8519 3.7871
BT 504 CTRP2 6.7617 9.7961 4.7276 4.2946
BT 145 CTRP2 6.7631 8.8779 5.1726 2.4874
BT 330 CTRP2 6.8962 8.8211 5.2854 1.8722
BT 159 CTRP2 6.9754 8.7236 5.3781 1.4328
BT 248 CTRP2 6.9756 10.515 4.5296 4.7781
BT 224 CTRP2 7.0045 8.2939 5.5831 0.6956
BT 422 CTRP2 7.0143 9.643 4.975 2.9316
BT 340 CTRP2 7.0704 8.7698 5.4119 1.2127
BT 231 CTRP2 7.1366 12.0261 3.9077 7.0693
BT 232 CTRP2 7.1386 10.7542 4.5272 4.5485
BT 440 CTRP2 7.1895 8.709 5.502 0.8049
BT 172 CTRP2 7.2015 9.5456 5.1383 2.0698
BT 112 CTRP2 7.2451 10.2981 4.8156 3.255
BT 239 CTRP2 7.3895 9.179 5.4053 0.9518
BT 131 CTRP2 7.3928 8.5846 5.6463 0.2889
BT 444 CTRP2 7.4653 8.8394 5.5795 0.4088
BT 179 CTRP2 7.4753 8.5423 5.6952 0.1656
BT 228 CTRP2 7.7221 9.0743 5.598 0.26
BT 359 CTRP2 7.7806 9.5373 5.4459 0.575
BT 320 CTRP2 7.8562 8.9942 5.6776 0.1028
BT 333 CTRP2 7.8849 15.6248 2.6879 10.7324
BT 482 CTRP2 7.9916 9.1501 5.6724 0.0864
BT 245 CTRP2 8.1347 9.6161 5.562 0.1979
BT 139 CTRP2 8.4036 9.622 5.6561 0.0521
BT 187 CTRP2 10.9131 19.3665 2.87 6.2238
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.2147 7.8023 5.303 2.8029
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NMC-G1 CTRP2 3.6214 51.3527 -18.6594 44.2344
AM-38 CTRP2 5.5618 16.7536 0.2825 23.2627
D283 Med CTRP2 5.7556 9.1284 4.2556 8.0948
LN-18 CTRP2 5.886 6.7826 5.5362 2.4627
GaMG CTRP2 6.1277 7.1975 5.5357 1.9827
KNS-60 CTRP2 6.3083 7.4286 5.558 1.5879
Hs 683 CTRP2 6.5196 8.1266 5.3678 2.0472
M059K CTRP2 6.5356 8.764 5.0691 3.2431
DK-MG CTRP2 6.5718 8.4105 5.2668 2.3801
SF268 CTRP2 6.6279 9.9042 4.5765 5.1309
U-251MG CTRP2 6.6519 8.4377 5.3083 2.0993
U-118MG CTRP2 6.715 8.9413 5.1095 2.8083
SNU-738 CTRP2 6.8232 8.8426 5.2289 2.1839
ONS-76 CTRP2 6.8489 8.4668 5.4199 1.4186
CCF-STTG1 CTRP2 6.8598 9.0902 5.1357 2.5027
SW1088 CTRP2 6.8729 10.2122 4.6041 4.6296
LN-229 CTRP2 6.9625 8.5422 5.4522 1.1782
Becker CTRP2 6.9967 9.0539 5.2398 1.9253
SNU-1105 CTRP2 7.0259 8.26 5.6081 0.6011
KNS-81 CTRP2 7.0875 8.5709 5.508 0.8695
Daoy CTRP2 7.1208 8.9479 5.3612 1.3419
SF126 CTRP2 7.171 8.9943 5.3688 1.2657
YH-13 CTRP2 7.2664 9.1306 5.3614 1.2015
SNU-489 CTRP2 7.5106 8.606 5.6858 0.1709
SNU-626 CTRP2 7.6187 8.806 5.6554 0.1903
SNU-466 CTRP2 7.6361 8.5962 5.7358 0.0753
SF295 CTRP2 7.7264 8.9597 5.6415 0.1823
GMS-10 CTRP2 7.7769 8.9349 5.6693 0.1288
8-MG-BA CTRP2 7.8066 10.6792 4.9785 2.0115
U-87MG ATCC CTRP2 7.8137 9.5665 5.4492 0.5491
CAS-1 CTRP2 7.8274 9.2258 5.5842 0.2499
KG-1-C CTRP2 7.8819 9.2315 5.6034 0.2005
KALS-1 CTRP2 8.2092 11.8081 4.704 2.5794
GB-1 CTRP2 8.6131 18.3389 1.884 12.5575
T98G CTRP2 9.1901 18.4218 2.2402 10.4713
SF539 CTRP2 9.2108 17.0837 2.8878 8.1078
DBTRG-05MG CTRP2 9.296 16.9238 3.0168 7.5286
42-MG-BA CTRP2 9.6105 18.8557 2.3111 9.6594
TM-31 CTRP2 9.6936 17.9494 2.7886 7.8635
SNU-201 CTRP2 10.0738 20.0735 2.0363 10.0138
A-172 CTRP2 10.5886 26.6463 -0.7593 17.6848
SNB-75 CTRP2 10.9407 22.547 1.4293 10.9309
GOS-3 CTRP2 10.9811 19.4612 2.8665 6.1667
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 5.834 6.9304 5.4158 3.0785
ESS-1 CTRP2 6.0122 7.6221 5.2285 3.4921
HEC-151 CTRP2 6.0747 7.2235 5.4799 2.3152
EN CTRP2 6.1576 7.2171 5.5495 1.8717
JHUEM-2 CTRP2 6.1579 7.6055 5.3563 2.6804
HEC-6 CTRP2 6.2934 7.4475 5.538 1.6936
HEC-59 CTRP2 6.4297 7.5498 5.5835 1.3077
MFE-296 CTRP2 6.4509 7.9872 5.3874 2.0687
HEC-1-A CTRP2 6.4666 7.9903 5.3969 2.0067
HEC-251 CTRP2 6.5203 8.3824 5.2443 2.5481
HEC-50B CTRP2 6.5765 8.4501 5.2509 2.4375
HEC-265 CTRP2 6.8646 8.1575 5.5677 0.8689
MFE-319 CTRP2 6.8722 8.6892 5.3317 1.7244
JHUEM-3 CTRP2 6.961 19.4363 0.0961 21.067
AN3-CA CTRP2 7.1754 12.1228 3.8885 7.0871
EFE-184 CTRP2 7.3087 9.3776 5.2762 1.4554
KLE CTRP2 7.5851 9.8351 5.2268 1.3683
RL95-2 CTRP2 7.9322 9.44 5.5471 0.2831
HEC-1-B CTRP2 8.1856 10.3928 5.2902 0.7504
HEC-108 CTRP2 10.3853 18.2345 3.0742 6.0774
JHUEM-1 CTRP2 13.4642 34.8376 -2.737 18.6495
Ishikawa (Heraklio) 02 ER- CTRP2 7.3868 8.4763 5.6844 0.2134
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCW CTRP2 5.7174 6.7045 5.4138 3.3575
KMRC-3 CTRP2 5.7974 9.0679 4.3222 7.7297
KMRC-1 CTRP2 5.946 6.791 5.5862 2.1246
TUHR10TKB CTRP2 6.0167 6.8103 5.6381 1.7619
UO-31 CTRP2 6.382 8.8694 4.9025 4.1864
SNU-1272 CTRP2 6.6325 8.147 5.4335 1.6298
BFTC-909 CTRP2 6.6835 8.8289 5.1421 2.7222
TUHR4TKB CTRP2 6.6965 8.1369 5.4788 1.3743
VMRC-RCZ CTRP2 6.7204 10.9605 4.1245 6.8517
786-O CTRP2 6.7443 8.4722 5.3524 1.8025
KMRC-20 CTRP2 7.1538 11.0528 4.3937 5.0658
A-498 CTRP2 7.2712 8.8399 5.4882 0.7846
Caki-1 CTRP2 7.3187 9.1601 5.3766 1.1037
RCC10RGB CTRP2 7.3659 9.5466 5.2334 1.5495
KMRC-2 CTRP2 7.3923 16.4899 1.8981 14.4681
ACHN CTRP2 7.4117 9.0195 5.4828 0.6998
TUHR14TKB CTRP2 7.5789 14.7927 2.8739 19.478
OS-RC-2 CTRP2 7.6904 9.4155 5.4534 0.6062
769-P CTRP2 8.1711 9.5387 5.6028 0.1339
Caki-2 CTRP2 10.027 19.0258 2.4963 8.4889
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OUMS-23 CTRP2 4.6546 6.9209 4.2228 10.8468
HT115 CTRP2 4.8789 6.3147 4.6896 8.4406
T84 CTRP2 5.1129 11.2718 2.6189 16.1811
SNU-C1 CTRP2 5.5466 8.5428 4.3595 8.1054
C2BBe1 CTRP2 5.5726 8.9932 4.1604 8.8785
COLO 320 CTRP2 5.628 10.0618 3.6789 10.7671
SNU-61 CTRP2 5.6311 6.6242 5.3651 3.7679
LS513 CTRP2 5.6453 6.8995 5.2514 4.1931
SNU-407 CTRP2 5.6533 7.1145 5.1565 4.5623
NCI-H747 CTRP2 5.7532 7.3541 5.1335 4.4305
SNU-1033 CTRP2 5.7554 8.1709 4.7316 6.1025
LS180 CTRP2 5.7777 8.2051 4.7345 6.0433
LoVo CTRP2 5.9023 7.2012 5.3437 3.2318
HCT 15 CTRP2 6.0457 7.2576 5.4389 2.5425
COLO201 CTRP2 6.0677 7.1517 5.5101 2.2012
CCK-81 CTRP2 6.0816 8.0684 5.0632 4.0529
RCM-1 [Human ESC] CTRP2 6.1054 6.9695 5.6316 1.6208
SNU-C5 CTRP2 6.1357 7.4895 5.3964 2.5524
SK-CO-1 CTRP2 6.1815 8.3236 5.017 4.061
CL-11 CTRP2 6.3335 8.0267 5.2826 2.6854
LS1034 CTRP2 6.3873 7.8013 5.4327 1.9798
SW1417 CTRP2 6.3984 7.9405 5.3727 2.2089
DLD-1 CTRP2 6.4392 7.5536 5.588 1.2769
MDST8 CTRP2 6.4564 7.8507 5.4572 1.7771
LS123 CTRP2 6.5946 8.1868 5.3898 1.8532
HCT 116 CTRP2 6.6444 8.3001 5.3689 1.8686
KM12 CTRP2 6.7873 8.3471 5.4375 1.4233
HT-55 CTRP2 6.8794 8.5987 5.3778 1.5411
HCC-56 CTRP2 6.9708 8.6387 5.4138 1.3077
NCI-H716 CTRP2 7.0496 8.8954 5.3439 1.4779
SNU-C4 CTRP2 7.0934 15.3398 2.2394 13.7362
SNU-503 CTRP2 7.1498 8.9612 5.3716 1.2763
HT-29 CTRP2 7.2714 8.9032 5.4617 0.8674
COLO205 CTRP2 7.4284 8.6444 5.6386 0.2906
COLO 678 CTRP2 7.4291 9.3419 5.3565 1.0757
SW948 CTRP2 7.4671 8.7832 5.602 0.3548
LS411N CTRP2 7.5314 8.6813 5.6666 0.1977
NCI-H508 CTRP2 7.6677 9.2739 5.4991 0.5019
GP2d CTRP2 7.7067 9.3511 5.4861 0.5135
RKO CTRP2 7.8959 11.1007 4.8417 2.4061
SW620 CTRP2 7.8977 9.5217 5.5025 0.3857
CW-2 CTRP2 8.1084 10.2493 5.3121 0.737
SW48 CTRP2 8.127 9.8875 5.4598 0.3828
SNU-C2A CTRP2 8.5931 11.6272 4.9823 1.3488
HCT 8 CTRP2 9.3285 16.9473 3.0263 7.4536
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLF CTRP2 5.1269 7.9507 4.2494 9.525
SNU-761 CTRP2 5.4725 7.5281 4.1387 3.2742
Li-7 CTRP2 5.5758 7.7236 4.7882 6.2602
JHH-1 CTRP2 5.6539 6.2606 5.5446 3.0015
JHH-4 CTRP2 5.6859 9.893 3.8137 10.0859
HuH-1 CTRP2 5.7356 7.235 5.1756 4.2949
HuH-6 CTRP2 5.8427 8.3042 4.7423 5.8753
JHH-5 CTRP2 5.8836 6.7147 5.5674 2.3386
SNU-182 CTRP2 5.9037 8.5403 4.6774 6.0234
SNU-449 CTRP2 6.2943 7.9281 5.3018 2.6708
SNU-878 CTRP2 6.3109 7.9294 5.3137 2.5938
Hep-G2 CTRP2 6.4326 10.3292 4.2162 6.9652
SNU-423 CTRP2 6.5715 8.2021 5.3669 1.9766
SK-HEP-1 CTRP2 6.6802 7.9116 5.5724 1.0411
SNU-387 CTRP2 6.9706 9.1717 5.1687 2.23
SNU-475 CTRP2 6.9709 10.7191 4.4269 5.2043
SNU-886 CTRP2 7.4824 10.4088 4.9123 2.595
SNU-398 CTRP2 7.5437 9.6185 5.298 1.1699
Hep 3B2.1-7 CTRP2 7.6453 10.4128 5.006 2.0752
JHH-2 CTRP2 7.8567 17.9028 1.5495 14.9116
JHH-6 CTRP2 12.489 31.762 -1.9211 18.0398
PLC/PRF/5 CTRP2 15.9992 43.753 -5.2986 20.6203
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 138 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DV-90 CTRP2 2.3456 6.094 1.9941 25.8578
COR-L88 CTRP2 3.4162 16.4635 -1.4902 32.5026
DMS 53 CTRP2 5.1059 6.6159 4.8225 7.2928
NCI-H1944 CTRP2 5.3329 6.9147 4.9323 6.2576
SW1271 CTRP2 5.5347 10.4513 3.4029 12.1048
NCI-H211 CTRP2 5.5857 8.1367 4.5951 7.0393
DMS 454 CTRP2 5.5986 7.3259 5.0026 5.3228
NCI-H522 CTRP2 5.6472 7.277 5.0723 4.9232
NCI-H2087 CTRP2 5.6844 8.8567 4.328 7.9407
T3M-10 CTRP2 5.7232 14.4057 1.5932 18.7073
HCC1588 CTRP2 5.7893 8.0705 4.8116 5.696
NCI-H1385 CTRP2 5.81 31.6566 -6.9576 35.4685
NCI-H1341 CTRP2 5.8148 9.1769 4.2829 7.8589
Calu-3 CTRP2 5.8946 8.3589 4.76 5.6949
SK-MES-1 CTRP2 5.9114 7.9272 4.99 4.6954
NCI-H1734 CTRP2 5.9222 7.1157 5.4038 2.9381
NCI-H1568 CTRP2 5.9382 7.3194 5.3163 3.2716
PC-14 CTRP2 5.9412 8.5895 4.6848 5.9171
EKVX CTRP2 5.95 10.4126 3.7811 9.6885
NCI-H838 CTRP2 5.9588 6.6698 5.6578 1.7982
MOR/CPR CTRP2 5.9698 6.874 5.5659 2.1601
NCI-H2405 CTRP2 5.9977 11.5539 3.2507 11.7879
A-549 CTRP2 6.0114 8.2487 4.9146 4.8131
NCI-H2122 CTRP2 6.0224 6.9319 5.5822 1.9856
ChaGo-K-1 CTRP2 6.0539 8.126 5.0115 4.3231
NCI-H2286 CTRP2 6.0545 15.9998 1.0751 19.7956
NCI-H1703 CTRP2 6.0565 11.7035 3.2249 11.7783
NCI-H1915 CTRP2 6.069 8.0038 5.0851 3.9849
NCI-H1373 CTRP2 6.0746 7.2384 5.4723 2.347
NCI-H2444 CTRP2 6.0747 8.6894 3.9923 2.9828
NCI-H1666 CTRP2 6.0769 7.3024 5.4423 2.4686
BEN CTRP2 6.0951 6.8588 5.6787 1.4422
NCI-H2172 CTRP2 6.1056 7.0162 5.6085 1.7173
NCI-H69 CTRP2 6.153 9.2453 4.5335 6.144
LUDLU-1 CTRP2 6.1581 7.662 5.3283 2.7976
NCI-H322 CTRP2 6.1706 7.1078 5.6138 1.5804
Lu-99 CTRP2 6.1723 7.4389 5.4507 2.2595
NCI-H1105 CTRP2 6.1729 11.6995 3.3232 11.1518
COR-L105 CTRP2 6.1862 7.9582 5.2029 3.2726
RERF-LC-MS CTRP2 6.1947 7.2783 5.5478 1.8146
NCI-H1155 CTRP2 6.2054 7.491 5.4505 2.2025
NCI-H647 CTRP2 6.211 9.1787 4.6139 5.699
HOP-62 CTRP2 6.2136 7.6846 5.3607 2.5633
NCI-H2081 CTRP2 6.2488 14.877 1.7973 16.9239
NCI-H1339 CTRP2 6.2523 7.3409 5.5602 1.6676
DMS 273 CTRP2 6.2568 8.1258 5.175 3.2644
LK2 CTRP2 6.2739 8.4576 5.0233 3.869
DMS 79 CTRP2 6.2759 15.7507 1.3828 18.326
NCI-H727 CTRP2 6.29 7.6705 5.4258 2.163
NCI-H810 CTRP2 6.3056 7.6766 5.4344 2.1018
EBC-1 CTRP2 6.3123 8.9848 4.7911 4.7732
NCI-H2228 CTRP2 6.3156 8.1543 5.2061 3.0337
COLO 668 CTRP2 6.3234 7.5978 5.4862 1.8598
NCI-H661 CTRP2 6.3323 7.6926 5.4462 2.0102
NCI-H2110 CTRP2 6.3333 8.4088 5.0935 3.473
Sq-1 CTRP2 6.3547 8.0935 5.2655 2.7215
NCI-H1184 CTRP2 6.3674 8.3283 5.1592 3.1421
NCI-H1755 CTRP2 6.3933 8.7286 4.9808 3.8408
NCI-H1838 CTRP2 6.4023 8.6756 5.0139 3.6881
LOU-NH91 CTRP2 6.4235 8.0266 5.3487 2.2685
HCC827 CTRP2 6.4248 8.1779 5.2757 2.5667
RERF-LC-A1 CTRP2 6.4261 7.6407 5.5376 1.4965
HCC2935 CTRP2 6.4373 8.6506 5.0525 3.4695
NCI-H1573 CTRP2 6.4478 8.9776 4.8989 4.09
NCI-H1092 CTRP2 6.4624 8.2491 5.268 2.5398
NCI-H292 CTRP2 6.4657 7.8227 5.4771 1.6834
SHP-77 CTRP2 6.4889 7.799 5.5042 1.5425
SK-LU-1 CTRP2 6.4891 8.1106 5.3544 2.1462
HCC95 CTRP2 6.5065 7.8259 5.5031 1.5229
NCI-H841 CTRP2 6.5109 7.7496 5.5422 1.3619
COR-L95 CTRP2 6.514 9.3702 4.7548 4.5789
NCI-H1355 CTRP2 6.5145 9.075 4.9008 3.9722
LC-1/sq-SF CTRP2 6.5168 7.9243 5.463 1.6685
DMS 114 CTRP2 6.534 9.9793 4.4686 5.7363
RERF-LC-Ad1 CTRP2 6.5546 10.1819 4.3839 6.0538
VMRC-LCD CTRP2 6.5677 8.6098 5.1673 2.7909
NCI-H2029 CTRP2 6.598 8.2368 5.3681 1.9349
HCC366 CTRP2 6.6059 9.6172 4.7016 4.6487
NCI-H2106 CTRP2 6.6588 10.0536 4.526 5.2898
NCI-H1792 CTRP2 6.6618 8.4056 5.3302 1.9985
NCI-H1581 CTRP2 6.6696 9.0298 5.0352 3.1767
HCC15 CTRP2 6.6711 8.371 5.3527 1.8968
HCC4006 CTRP2 6.6731 8.2048 5.4324 1.582
NCI-H1869 CTRP2 6.6898 8.8894 5.1172 2.8138
NCI-H2170 CTRP2 6.7088 9.5341 4.8175 4.0076
HCC2108 CTRP2 6.7143 8.386 5.3738 1.7578
NCI-H650 CTRP2 6.7229 8.6019 5.2773 2.1261
HCC78 CTRP2 6.747 9.1517 5.0301 3.0828
LCLC-97TM1 CTRP2 6.7515 8.7525 5.2246 2.2962
NCI-H2291 CTRP2 6.7998 10.0114 4.6497 4.555
NCI-H2196 CTRP2 6.8038 8.5272 5.3644 1.6821
NCI-H441 CTRP2 6.8174 8.6642 5.3091 1.8785
NCI-H1563 CTRP2 6.8268 8.7561 5.2719 2.0109
NCI-H1694 CTRP2 6.8464 11.8212 3.7941 8.005
NCI-H226 CTRP2 6.9118 8.4653 5.4576 1.211
NCI-H524 CTRP2 6.9145 8.7604 5.3248 1.7005
HARA [Human squamous cell lung carcinoma] CTRP2 6.9151 8.5554 5.4189 1.3485
NCI-H2342 CTRP2 6.9572 11.4976 4.036 6.829
NCI-H1975 CTRP2 6.9951 15.0113 2.3265 13.5821
NCI-H526 CTRP2 7.0003 9.1065 5.2177 2.0054
NCI-H1650 CTRP2 7.0413 9.2456 5.1787 2.105
NCI-H2009 CTRP2 7.0903 15.3014 2.256 13.6795
NCI-H2030 CTRP2 7.1449 9.6461 5.0572 2.4444
NCI-H1793 CTRP2 7.1779 11.7069 4.0932 6.2498
NCI-H196 CTRP2 7.2299 9.0029 5.3972 1.1133
LCLC-103H CTRP2 7.4428 9.02 5.4974 0.6372
SBC-5 CTRP2 7.4969 8.567 5.6946 0.1604
IA-LM CTRP2 7.535 9.0179 5.5405 0.4687
HCC1833 CTRP2 7.5483 16.5347 1.9937 13.8586
NCI-H889 CTRP2 7.5546 9.3145 5.4306 0.7539
HCC1171 CTRP2 7.5652 9.3045 5.4398 0.7206
NCI-H358 CTRP2 7.5696 9.6977 5.2776 1.2143
NCI-H460 CTRP2 7.6359 12.8336 3.8671 6.4838
NCI-H1623 CTRP2 7.6602 9.7198 5.3146 1.0251
KNS-62 CTRP2 7.7011 12.2195 4.2044 5.0559
RERF-LC-Ad2 CTRP2 7.7201 14.6089 3.0656 9.5314
NCI-H1299 CTRP2 7.742 9.6128 5.3982 0.7241
NCI-H2126 CTRP2 7.9858 9.4298 5.572 0.2224
NCI-H446 CTRP2 8.0258 13.964 3.5893 7.0301
NCI-H23 CTRP2 8.1766 19.9943 0.7568 16.9842
HCC1438 CTRP2 8.2628 15.9726 2.7854 9.7912
COLO 699 CTRP2 8.3276 10.4614 5.326 0.5888
NCI-H2023 CTRP2 8.4413 9.999 5.541 0.158
CAL-12T CTRP2 8.478 18.273 1.8204 12.9846
Calu-6 CTRP2 8.5011 10.0154 5.557 0.1282
HCC1195 CTRP2 8.5759 10.1117 5.5506 0.1229
LXF 289 CTRP2 8.7078 14.1375 3.9431 4.8097
NCI-H2085 CTRP2 8.7185 10.4111 5.4986 0.1571
NCI-H1435 CTRP2 8.7235 16.1575 3.0085 8.3013
NCI-H520 CTRP2 8.7724 19.7484 1.3113 14.2647
NCI-H1395 CTRP2 8.7819 10.9481 5.3308 0.3966
EPLC-272H CTRP2 9.2333 11.1974 5.4122 0.1658
HCC2279 CTRP2 9.7269 21.4683 1.1436 13.4217
HOP-92 CTRP2 9.7674 24.6489 -0.3673 17.8046
HCC44 CTRP2 9.7686 22.7171 0.5707 15.1348
Lu-65 CTRP2 10.1243 23.4088 0.4821 14.9019
Calu-1 CTRP2 12.5349 23.7841 1.8216 7.9511
Hs 888.Lu CTRP2 6.4832 7.9074 5.4484 1.7742
⏷ Show the Full List of 138 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.4128 7.7835 5.4595 1.832
Yamato-SS CTRP2 6.7135 8.2885 5.4189 1.5836
TE 617.T CTRP2 5.0249 7.5359 4.3408 9.4065
A-204 CTRP2 5.4012 16.4885 0.2771 23.617
G-401 CTRP2 5.9538 13.5116 2.235 15.8903
KYM-1 CTRP2 5.9538 8.2358 4.8723 5.1043
BT-16 CTRP2 5.9978 7.8041 5.1255 3.9534
Rh41 CTRP2 6.0508 7.0526 5.5456 2.0842
TE 441.T CTRP2 6.1312 9.604 4.3364 7.0127
BT-12 CTRP2 6.1922 7.7962 5.2884 2.9038
G-402 CTRP2 6.3231 11.3846 3.6029 9.7172
TTC-709 CTRP2 6.5244 8.2039 5.3337 2.178
Tm87-16 CTRP2 6.718 8.4548 5.3437 1.8705
SK-UT-1 CTRP2 6.9426 8.8892 5.2826 1.8271
MES-SA CTRP2 6.9439 8.4758 5.4712 1.1293
RKN CTRP2 7.0043 8.3325 5.5666 0.7486
HT-1080 CTRP2 7.0978 8.2803 5.6346 0.4737
RD CTRP2 7.1904 13.5499 3.1987 9.8509
GCT CTRP2 7.4591 9.9656 5.0996 1.9313
SW982 CTRP2 7.581 8.8335 5.6304 0.248
SK-LMS-1 CTRP2 7.7441 12.2848 4.2016 5.0095
Hs 729.T CTRP2 7.8361 13.9115 3.4854 7.7085
Rh18 CTRP2 8.024 9.3232 5.6242 0.1361
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 6.4221 8.6389 5.0469 3.5178
H-STS CTRP2 7.2295 8.8969 5.4427 0.9627
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 6.8673 13.323 3.066 10.929
COV434 CTRP2 5.4319 7.1459 4.9262 6.0334
COV644 CTRP2 5.6206 7.3761 4.9991 5.2865
A2780 CTRP2 5.69 6.5973 5.4365 3.333
OVCAR-5 CTRP2 5.9445 7.5506 5.2065 3.7197
TYK-nu CTRP2 5.9961 7.6214 5.2153 3.5794
OAW42 CTRP2 6.0402 6.9962 5.565 2.0233
Caov-3 CTRP2 6.0692 7.2728 5.4507 2.4481
OV-90 CTRP2 6.0722 7.5802 5.2995 3.0779
OV56 CTRP2 6.1817 8.8387 4.7599 5.1399
Kuramochi CTRP2 6.2234 8.5666 4.9292 4.3535
OVTOKO CTRP2 6.3934 8.6236 5.0328 3.6243
RMG-I CTRP2 6.444 8.2583 5.2503 2.6412
EFO-27 CTRP2 6.4444 8.4227 5.1699 2.9719
TOV-112D CTRP2 6.447 7.9806 5.3878 2.0727
SK-OV-3 CTRP2 6.4513 7.9515 5.405 1.9963
OV7 CTRP2 6.4667 8.3183 5.2373 2.6593
ONCO-DG-1 CTRP2 6.4865 9.5128 4.6635 5.0049
SNU-8 CTRP2 6.4893 9.2139 4.8134 4.3765
OVCAR-8 CTRP2 6.4925 7.811 5.5008 1.551
SNU-840 CTRP2 6.4982 7.9761 5.4255 1.8449
MCAS CTRP2 6.506 8.0342 5.403 1.9246
OC 314 CTRP2 6.5589 8.8512 5.0433 3.3127
OVCAR-4 CTRP2 6.5785 8.7517 5.1059 3.0254
SNU-119 CTRP2 6.5985 13.5142 2.7606 12.6212
OVSAHO CTRP2 6.6473 7.6776 5.6587 0.7625
OVK18 CTRP2 6.6932 8.4009 5.3531 1.8662
COV362 CTRP2 6.7013 17.6772 -0.6714 16.1817
HEY A8 CTRP2 6.8021 8.099 5.5587 0.9614
JHOS-2 CTRP2 6.831 9.2766 5.0275 2.9733
IGROV-1 CTRP2 6.9248 9.3804 5.0407 2.7914
EFO-21 CTRP2 7.0629 8.7038 5.4369 1.1328
OAW28 CTRP2 7.2214 9.9705 4.9541 2.7471
JHOC-5 CTRP2 7.2347 8.5223 5.601 0.4813
JHOM-1 CTRP2 7.3024 9.4886 5.2233 1.6488
TOV-21G CTRP2 7.3511 8.8318 5.5305 0.6033
ES2 CTRP2 7.5723 8.5677 5.7227 0.1018
OVISE CTRP2 7.9612 8.9171 5.7402 0.0352
DOV13 CTRP2 8.3671 9.8496 5.566 0.1415
FU-OV-1 CTRP2 8.9618 21.7006 0.4944 16.5497
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.0087 12.3988 3.6307 8.4052
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 5.7741 7.7732 4.9455 5.1686
NCI-H28 CTRP2 6.2198 7.6196 5.3978 2.3978
NCI-H2452 CTRP2 6.3965 9.8383 4.4323 6.1259
NCI-H2052 CTRP2 7.2015 14.1736 2.8993 11.0188
JL-1 CTRP2 7.2821 9.9056 5.0218 2.4146
IST-Mes1 CTRP2 7.6476 10.3031 5.0561 1.8952
ACC-MESO-1 CTRP2 7.7487 13.0606 3.8349 6.4513
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 CTRP2 3.3823 37.6168 -12.0116 42.4334
LNCaP clone FGC CTRP2 6.1092 9.5539 4.3433 7.0256
VCaP CTRP2 6.4471 8.1646 5.2983 2.4391
DU145 CTRP2 6.7018 8.8418 5.1484 2.6705
PaCa-3 CTRP2 6.7234 7.9566 5.5773 0.9761
22Rv1 CTRP2 8.7188 10.8317 5.3485 0.3852
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 6.2717 7.5221 5.4854 1.9459
A-253 CTRP2 6.9607 11.7523 3.9134 7.3265
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 4.5276 6.4038 4.2786 10.9946
SNU-16 CTRP2 5.4455 6.1975 5.3434 4.3555
SNU-620 CTRP2 5.448 6.433 5.2577 4.6737
Fu97 CTRP2 5.5107 10.8004 3.2082 12.9543
OCUM-1 CTRP2 5.5442 7.3249 4.951 5.662
SNU-216 CTRP2 5.5753 8.9579 4.1804 8.7893
NUGC-4 CTRP2 5.5776 6.5135 5.3595 3.9281
SNU-5 CTRP2 5.603 7.391 4.9753 5.4251
KE-39 CTRP2 5.6364 7.5639 4.9226 5.5666
NUGC-3 CTRP2 5.8849 10.5444 3.6601 10.3212
SH-10-TC CTRP2 5.9086 6.5937 5.6498 1.9409
SNU-1 CTRP2 6.049 8.3653 4.8878 4.8529
HGC-27 CTRP2 6.0627 7.5733 5.2951 3.1145
SNU-719 CTRP2 6.0977 7.8602 5.1805 3.5296
23132/87 CTRP2 6.1418 7.2194 5.536 1.9563
IM95 CTRP2 6.1878 7.5571 5.404 2.4276
Hs 746.T CTRP2 6.1909 8.8499 4.7618 5.1151
HuG1-N CTRP2 6.3093 8.6646 4.9479 4.1223
MKN45 CTRP2 6.4045 7.8438 5.4243 1.9883
ECC10 CTRP2 6.5201 7.9305 5.4622 1.6668
MKN74 CTRP2 6.5421 8.6642 5.1226 3.0134
MKN7 CTRP2 6.5873 9.4184 4.7857 4.3304
NCI-N87 CTRP2 6.6099 8.5975 5.2028 2.5835
SNU-668 CTRP2 6.6272 9.2639 4.8908 3.8333
AGS CTRP2 6.6659 7.951 5.5458 1.1566
MKN1 CTRP2 6.8288 10.8059 4.2815 6.0246
LMSU CTRP2 7.0242 10.6486 4.4989 4.8307
ECC12 CTRP2 7.0792 8.7698 5.4168 1.187
GSU CTRP2 7.1666 7.7132 5.8706 0.0181
NCC-StC-K140 CTRP2 7.2047 9.5533 5.1367 2.0721
SNU-601 CTRP2 12.6135 31.2773 -1.6069 17.1784
SNG-M CTRP2 6.6252 8.6222 5.2015 2.5665
SNU-1077 CTRP2 7.1414 8.9522 5.3709 1.2871
SNU-685 CTRP2 9.3142 16.8686 3.054 7.3702
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2 6.0211 7.5034 5.2954 3.1938
B-CPAP CTRP2 6.2184 7.331 5.5397 1.8084
SW579 CTRP2 6.2814 16.8572 0.8342 20.1247
FTC-238 CTRP2 6.4805 7.9511 5.4255 1.8707
8505C CTRP2 6.5483 8.1656 5.3687 2.0022
BHT-101 CTRP2 6.6295 11.1703 3.9513 7.7243
CGTH-W-1 CTRP2 6.8292 8.3671 5.4536 1.3152
ML-1 [Human leukemia] CTRP2 6.8431 8.9166 5.2069 2.2442
CAL-62 CTRP2 7.496 8.7887 5.6121 0.3191
FTC-133 CTRP2 7.6322 9.0129 5.5842 0.3218
TT2609-C02 CTRP2 8.6184 10.1947 5.5373 0.1304
TT CTRP2 9.3408 22.1267 0.5573 15.7927
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 1.0825 9.122 -0.4382 37.1291
SNU-1214 CTRP2 4.9576 9.6824 3.2558 13.9807
BICR 22 CTRP2 5.1524 7.6731 4.4046 8.8325
CAL-33 CTRP2 5.194 9.8905 3.3736 12.9643
PE/CA-PJ15 CTRP2 5.2238 8.1311 4.2574 9.2609
PE/CA-PJ49 CTRP2 5.5771 9.2589 4.0328 9.4008
PE/CA-PJ34 (clone C12) CTRP2 5.6694 9.9115 3.7902 10.2183
SCC-25 CTRP2 6.0231 7.4167 5.3404 3.0003
BICR 31 CTRP2 6.2146 9.0838 4.6641 5.4815
BICR 6 CTRP2 6.251 7.3738 5.543 1.7406
SNU-1076 CTRP2 6.2828 7.3239 5.5908 1.4929
BHY CTRP2 6.3137 8.9181 4.8254 4.6272
PE/CA-PJ41 (clone D2) CTRP2 6.3569 8.2231 5.2033 2.9764
BICR 18 CTRP2 6.3949 9.0178 4.8388 4.4301
SCC-9 CTRP2 6.4978 8.3664 5.2361 2.616
FaDu CTRP2 6.5304 7.8381 5.5131 1.451
CAL-27 CTRP2 6.6106 9.0696 4.9738 3.5179
YD-8 CTRP2 6.6481 10.9889 4.0555 7.2602
SNU-1041 CTRP2 6.6621 8.187 5.4337 1.5908
HSC-4 CTRP2 6.6654 9.0177 5.0381 3.1709
SNU-46 CTRP2 6.7458 8.7936 5.2012 2.3971
SNU-899 CTRP2 6.8442 8.1412 5.5636 0.9024
BICR 16 CTRP2 6.9309 12.934 3.3076 9.8481
HSC-2 CTRP2 6.933 12.6923 3.4288 9.3534
SNU-1066 CTRP2 7.3116 9.2676 5.3261 1.2798
HSC-3 CTRP2 7.8267 16.0472 2.4394 11.7617
SCC-4 CTRP2 8.3195 9.9031 5.5296 0.2002
Detroit 562 CTRP2 8.8489 19.3351 1.5664 13.2979
BICR 56 CTRP2 11.8099 23.8275 1.3747 10.0873
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J-BV CTRP2 5.8874 7.4487 5.2075 3.8328
RT-112 CTRP2 5.935 7.138 5.404 2.9107
253J CTRP2 5.9942 6.8124 5.6178 1.8925
U-BLC1 CTRP2 6.0422 7.4858 5.3218 3.0415
647V CTRP2 6.0432 7.2275 5.4518 2.4932
HT-1197 CTRP2 6.1675 7.1226 5.6041 1.6261
TCCSUP CTRP2 6.2055 7.5886 5.4021 2.4044
JMSU-1 CTRP2 6.2621 7.5557 5.4616 2.0604
RT-4 CTRP2 6.307 11.6672 3.4488 10.3829
UM-UC-1 CTRP2 6.3806 12.6824 3.0013 12.0665
KU-19-19 CTRP2 6.427 11.1598 3.7981 8.7175
SCaBER CTRP2 6.444 9.8025 4.4871 5.8135
BC-3C CTRP2 6.4705 15.7145 1.5597 17.3386
CAL-29 CTRP2 6.7663 8.53 5.3394 1.8253
KMBC-2 CTRP2 6.8572 10.3819 4.5101 5.039
VM-CUB-1 CTRP2 6.9206 9.7979 4.8381 3.6078
HT-1376 CTRP2 7.0364 10.3019 4.6749 4.0996
UM-UC-3 CTRP2 7.0524 9.2567 5.1804 2.0851
639V CTRP2 7.401 8.6212 5.6359 0.3083
SW1710 CTRP2 7.7316 13.1644 3.7734 6.7193
BFTC-905 CTRP2 7.8641 9.0571 5.6586 0.1245
T24 CTRP2 7.9716 12.1141 4.4257 3.8589
5637 CTRP2 8.2442 18.8506 1.3693 14.8938
J82 CTRP2 8.9799 20.6293 1.03 14.8645
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.4919 8.9787 5.5367 0.5018

References

1 Drugs and Targets in Fibrosis. Front Pharmacol. 2017 Nov 23;8:855.
2 Pyrazolone based TGFbetaR1 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jan 1;20(1):326-9.
3 Activin/nodal signaling switches the terminal fate of human embryonic stem cell-derived trophoblasts. J Biol Chem. 2015 Apr 3;290(14):8834-48.