Details of the Drug

General Information of Drug (ID: DM4Y95F)

Drug Name
Cephaloridine
Synonyms
cephaloridine; cefaloridine; Cefaloridin; Cephaloridin; Cephaloridinum; Cepaloridin; Cefalorizin; Cephalomycine; Cefaloridinum; Cepalorin; Cefaloridina; Loridine; Ceflorin; 50-59-9; Kefloridin; Glaxoridin; Ceporin; Vioviantine; Intrasporin; Sefacin; Keflordin; Deflorin; Cilifor; Ceporan; Sasperin; Faredina; Ceporine; Keflodin; Verolgin; Lloncefal; Kefspor; Ampligram; Betaine cephaloridine; CHEBI:3537; UNII-LVZ1VC61HB; Cefaloridinum [INN-Latin]; Cefaloridina [INN-Spanish]; N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate; SCH
Indication
Disease Entry ICD 11 Status REF
Gram-positive bacterial infection 1B74-1G40 Withdrawn from market [1]
ATC Code
J01DB02: Cephaloridine
J01DB: First-generation cephalosporins
J01D: OTHER BETA-LACTAM ANTIBACTERIALS
J01: ANTIBACTERIALS FOR SYSTEMIC USE
J: ANTIINFECTIVES FOR SYSTEMIC USE
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 415.5
Logarithm of the Partition Coefficient (xlogp) 1.9
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 3: high solubility and low permeability [2]
Clearance
The drug present in the plasma can be removed from the body at the rate of 3.3 mL/min/kg [3]
Elimination
The drug is excreted via renal []
Half-life
The concentration or amount of drug in body reduced by one-half in 1.5 hours [3]
MRTD
The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 206.3 micromolar/kg/day [4]
Unbound Fraction
The unbound fraction of drug in plasma is 0.8% [3]
Vd
Fluid volume that would be required to contain the amount of drug present in the body at the same concentration as in the plasma 0.46 L/kg [3]
Adverse Drug Reaction (ADR)
ADR Term Variation Related DOT DOT ID REF
Injury Not Available GPX1 OTE2O72Q [5]
Chemical Identifiers
Formula
C19H17N3O4S2
IUPAC Name
(6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Canonical SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=CC=C4
InChI
InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18-/m1/s1
InChIKey
CZTQZXZIADLWOZ-CRAIPNDOSA-N
Cross-matching ID
PubChem CID
5773
ChEBI ID
CHEBI:3537
CAS Number
50-59-9
UNII
LVZ1VC61HB
DrugBank ID
DB09008
TTD ID
D0F8IO
VARIDT ID
DR00612
INTEDE ID
DR0285

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [6]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [7]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [8]
Beta-lactamase (blaB) DEKGVS4 PENA_BURM1 Substrate [9]
Beta-lactamase (blaB) DET9I1W BLAC_BACUN Substrate [10]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Drug Response [5]
Organic anion transporter 3 (SLC22A8) OT8BY933 S22A8_HUMAN Regulation of Drug Effects [7]
Solute carrier family 22 member 6 (SLC22A6) OTKRCBVM S22A6_HUMAN Regulation of Drug Effects [7]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.2456 1.6323 0.2452 33.0106
JK1 CTRP2 0.3338 2.0093 0.3312 32.4315
JM1 CTRP2 -0.0382 1.5817 -0.0394 34.9005
KMS-21-BM CTRP2 -3.0449 1.677 -3.1352 54.5985
SU-DHL-5 CTRP1 -2.9238 -1.4045 -2.9239 98.247
JURL-MK1 CTRP2 -2.7427 -0.3624 -2.7441 52.8756
LAMA-84 CTRP2 -2.7325 1.2401 -2.7767 52.7264
KE-97 CTRP2; CTRP1 -2.7142 -0.6606 -2.7146 52.6899
SUP-T1 CTRP2 -2.6958 2.4072 -2.8453 52.3743
AMO1 CTRP2; CTRP1 -2.6074 1.0892 -2.6394 51.9366
NB4 CTRP2 -2.5595 -1.9486 -2.5595 51.6629
JVM-3 CTRP2 -2.554 -1.3266 -2.554 51.6264
F-36P CTRP2 -2.5346 0.1514 -2.5389 51.4911
M-07e CTRP2 -2.516 2.0245 -2.6121 51.3034
KMS-26 CTRP2 -2.468 -1.9539 -2.468 51.0547
MOLM-16 CTRP2; CTRP1 -2.4628 0.7474 -2.4781 51.0084
NU-DUL-1 CTRP2; CTRP1 -2.4216 -1.8685 -2.4216 50.7457
MOLT-16 CTRP2 -2.3957 0.2049 -2.3995 50.5718
SR CTRP2 -2.3827 1.0843 -2.4082 50.4792
Ku812 CTRP2; CTRP1 -2.3245 2.5388 -2.467 50.0939
NCO2 CTRP2 -2.2699 -0.2193 -2.2706 49.7376
WSU-DLCL2 CTRP2; CTRP1 -2.2528 -1.6369 -2.2528 49.6236
RPMI-8402 CTRP2 -2.242 -0.4105 -2.2422 49.5519
SU-DHL-6 CTRP2 -2.1876 1.3906 -2.2219 49.2059
P31/FUJ CTRP2 -2.1002 -1.566 -2.1002 48.6087
PL21 CTRP2; CTRP1 -2.0828 -1.3273 -2.0828 48.4931
THP-1 CTRP2; CTRP1 -2.0598 -0.4404 -2.0598 48.34
KM-H2 CTRP2 -2.0427 0.3347 -2.0453 48.2296
U-937 CTRP2; CTRP1 -2.0299 -0.9992 -2.0299 48.1411
SU-DHL-1 CTRP2 -2.0046 -0.7043 -2.0046 47.9731
Karpas-422 CTRP2 -1.9993 1.3292 -2.0251 47.9666
DEL CTRP2 -1.9435 -1.1122 -1.9435 47.5669
SKM-1 CTRP2; CTRP1 -1.9288 -1.321 -1.9288 47.4688
SUP-M2 CTRP2 -1.9256 -0.5909 -1.9256 47.4477
MOLM-13 CTRP2 -1.9214 1.3347 -1.9453 47.4521
Peer CTRP2 -1.9053 0.6543 -1.9105 47.3214
KMS-11 CTRP2; CTRP1 -1.7798 0.1793 -1.7805 46.4799
Jurkat CTRP2 -1.6084 0.5478 -1.6103 45.3433
P12-Ichikawa CTRP2 -1.6048 0.8414 -1.6097 45.3259
SU-DHL-4 CTRP2; CTRP1 -1.5596 1.3529 -1.5755 45.0495
OCI-AML-2 CTRP2 -1.5492 0.2426 -1.5496 44.9456
NALM-6 CTRP2 -1.4676 0.7197 -1.47 44.4084
HEL CTRP2 -1.4335 1.3407 -1.4465 44.2078
SU-DHL-8 CTRP2 -1.4246 2.6706 -1.5278 44.3282
Ri-1 CTRP2 -1.4069 2.7269 -1.5155 44.2231
KO52 CTRP2 -1.3637 0.1399 -1.3638 43.7116
CMK CTRP2 -1.3338 1.6308 -1.3548 43.5658
KMS-27 CTRP2 -1.3285 0.7974 -1.3307 43.4835
RCH-ACV CTRP2 -1.3125 1.7145 -1.3365 43.4319
RPMI-8226 CTRP2; CTRP1 -1.2801 0.3039 -1.2802 43.1555
Ki-JK CTRP2 -1.2322 1.4009 -1.2432 42.8672
NU-DHL-1 CTRP2 -1.2279 1.1779 -1.234 42.8255
DB CTRP2 -1.2252 0.9724 -1.2284 42.7992
OCI-AML-3 CTRP2; CTRP1 -1.1831 -0.5493 -1.1831 42.5101
ALL-SIL CTRP2 -1.1499 0.9636 -1.1525 42.2973
NOMO-1 CTRP2; CTRP1 -1.1383 0.5683 -1.1388 42.2138
HEL 92.1.7 CTRP2 -1.0786 1.6101 -1.0929 41.8564
SEM CTRP2 -1.0559 -0.0443 -1.0559 41.6644
697 CTRP2 -1.0536 0.3207 -1.0537 41.6492
JJN-3 CTRP2 -1.0318 -0.2798 -1.0318 41.5039
L-428 CTRP2 -1.0268 0.5487 -1.027 41.4714
K-562 CTRP2 -0.9721 1.4103 -0.9793 41.1291
CML-T1 CTRP2 -0.9691 0.9117 -0.9703 41.0907
U266B1 CTRP2 -0.9082 0.5545 -0.9083 40.6824
Granta-519 CTRP2 -0.9041 1.0924 -0.9063 40.6616
BV-173 CTRP2 -0.8849 1.5799 -0.8947 40.5572
SU-DHL-10 CTRP2 -0.8437 2.4072 -0.8924 40.3935
HDLM-2 CTRP2 -0.8394 1.8319 -0.856 40.2749
MV4-11 CTRP2 -0.8365 1.6575 -0.8475 40.2392
L-540 CTRP2 -0.826 1.3747 -0.8308 40.1503
PF-382 CTRP2 -0.7219 1.8929 -0.7381 39.4935
A4/Fukuda CTRP2 -0.6992 1.2218 -0.7012 39.2985
HT CTRP2; CTRP1 -0.684 1.409 -0.6879 39.2039
BL-70 CTRP2; CTRP1 -0.6452 1.0246 -0.6459 38.9352
KE-37 CTRP2 -0.6173 0.9231 -0.6177 38.7489
Kasumi-2 CTRP2 -0.6041 0.8111 -0.6042 38.66
EHEB CTRP2 -0.5885 2.7201 -0.6512 38.7451
HH [Human lymphoma] CTRP2 -0.5646 1.7383 -0.5731 38.4243
AML-193 CTRP2 -0.5628 2.6436 -0.6177 38.5525
RS4;11 CTRP2 -0.5185 1.9436 -0.532 41.0347
EM-2 CTRP2 -0.5157 1.754 -0.5238 38.098
MOLM-6 CTRP2 -0.4727 1.6913 -0.4788 37.8058
KMS-34 CTRP2 -0.4664 1.0548 -0.4668 37.7454
KCL-22 CTRP2 -0.4353 2.2841 -0.461 37.619
TF-1 CTRP2 -0.4238 2.2254 -0.4462 37.5323
Karpas-299 CTRP2 -0.4171 1.2184 -0.4179 37.4189
HuT 78 CTRP2 -0.3855 1.7077 -0.3908 37.2234
KMS-12-BM CTRP2 -0.3824 1.4853 -0.3848 37.1933
Raji CTRP2 -0.377 2.1283 -0.3939 37.2039
Pfeiffer CTRP2 -0.3506 0.631 -0.3506 36.9741
KYO-1 CTRP2 -0.333 1.2581 -0.3337 36.8595
KHM-1B CTRP2 -0.3181 1.764 -0.3236 36.7761
HPB-ALL CTRP2 -0.2444 1.951 -0.2529 36.2957
RPMI-6666 CTRP2 -0.2213 1.8612 -0.2274 36.1344
DoHH2 CTRP2 -0.2104 1.8093 -0.2154 36.0581
GA-10 CTRP2 -0.1988 0.3188 -0.1988 35.9645
EJM CTRP2; CTRP1 -0.1769 1.4511 -0.1779 35.8224
MC116 CTRP2; CTRP1 -0.1351 1.8209 -0.1395 35.5554
Namalwa CTRP2 -0.1255 0.8874 -0.1255 35.477
TALL-1 [Human adult T-ALL] CTRP2 -0.1161 2.0149 -0.1241 35.4408
EB1 CTRP2 -0.1121 1.4584 -0.113 35.3909
Daudi CTRP2 -0.0888 1.2467 -0.089 35.234
OCI-Ly3 CTRP2 -0.0843 1.0268 -0.0843 35.2033
KMS-20 CTRP2 -0.079 1.0939 -0.0791 35.1681
OCI-AML-5 CTRP2 -0.0361 0.7434 -0.0361 34.8824
OPM-2 CTRP2 -0.0001 0.9396 -0.0001 34.6432
Mino CTRP2 0.0261 0.8817 0.0261 34.4691
MOLT-13 CTRP2 0.0262 1.1379 0.0262 34.4681
SUP-T11 CTRP2 0.072 2.7191 0.0386 34.2735
SET-2 CTRP2 0.1108 2.0522 0.1053 33.9242
ST486 CTRP2 0.1273 0.9311 0.1273 33.7962
OCI-M1 CTRP2 0.1552 2.0247 0.1507 33.6255
OCI-Ly19 CTRP2 0.1673 1.3364 0.1673 33.53
SUP-B15 CTRP2 0.175 1.1088 0.175 33.4786
SIG-M5 CTRP2 0.2036 0.9185 0.2036 33.2884
Mono-Mac-1 CTRP2 0.2148 2.8698 0.1767 33.34
Hs 611.T CTRP2 0.2195 1.5405 0.2192 33.1839
MOLP-2 CTRP2 0.2255 3.6032 0.1098 33.5202
L-363 CTRP2 0.2441 2.743 0.2156 33.1136
Kasumi-1 CTRP2 0.2774 1.8615 0.2759 32.8027
HL-60 CTRP2 0.3369 1.1526 0.3369 32.4022
MOLP-8 CTRP2 0.378 1.8002 0.3773 32.1311
Reh CTRP2 0.3834 1.2585 0.3834 32.0931
MOTN-1 CTRP2 0.3918 1.4887 0.3917 32.0372
Ci-1 CTRP2 0.4135 1.8184 0.4128 31.8952
MM1.S CTRP2 0.4373 2.3771 0.4294 31.7607
KMS-18 CTRP2 0.4699 2.3003 0.4643 31.5362
GDM-1 CTRP2; CTRP1 0.5205 2.1415 0.5179 31.19
CA46 CTRP2 0.602 2.4692 0.5945 30.6641
LP-1 CTRP2; CTRP1 0.6064 2.7055 0.5911 30.6611
RL CTRP2 0.62 1.8983 0.6196 30.5211
JeKo-1 CTRP2 0.6574 1.9174 0.657 30.2725
SUP-HD1 CTRP2 0.6755 2.5306 0.6676 30.1768
P3HR-1 CTRP2; CTRP1 0.7763 6.1308 0.0918 31.7078
MHH-CALL-4 CTRP2 0.7993 2.0797 0.7987 29.3289
HD-MY-Z CTRP2 0.845 1.8943 0.8449 29.0236
NCI-H929 CTRP2 0.8716 2.2439 0.8704 28.8505
A3/Kawakami CTRP2 0.88 1.3144 0.88 28.7907
SK-MM-2 CTRP2 1.1385 2.399 1.1376 29.1363
OCI-Ly10 CTRP2; CTRP1 1.1444 3.6655 1.0799 27.2493
MHH-CALL-3 CTRP2 1.1584 5.862 0.5945 28.8536
Mono-Mac-6 CTRP2 1.1759 7.5421 0.0067 30.673
ME1 CTRP2 1.4915 3.5261 1.4587 24.8341
Toledo CTRP2 2.2904 4.489 2.1876 19.7619
Karpas-620 CTRP2 3.2692 5.2581 3.0785 13.5699
REC-1 CTRP2 3.6104 8.8927 1.9101 17.2068
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 0.2106 2.5851 0.1896 35.8472
TE15 CTRP2 1.0523 4.6481 0.8127 28.4564
KYSE-70 CTRP2 -5.2688 -3.3767 -5.2688 69.6511
TE-14 CTRP2 -4.5452 0.2368 -4.5939 63.8064
TE-4 CTRP2 -4.0359 1.4686 -4.1579 64.0764
KYSE-180 CTRP2 -3.2872 -2.0449 -3.2872 56.5022
TE-9 CTRP2 -3.0855 0.0287 -3.0937 55.1077
TE-6 CTRP2 -2.5976 -0.7561 -2.5978 51.9159
TE-10 CTRP2 -1.9197 1.6284 -1.9583 47.4578
KYSE-510 CTRP2 -1.8872 -0.4966 -1.8872 47.1924
KYSE-140 CTRP2; CTRP1 -1.8071 4.6032 -2.2913 47.1332
OE19 CTRP2 -1.2259 4.9255 -1.7381 43.7329
KYSE-410 CTRP2; CTRP1 -0.7907 2.8037 -0.8722 40.1316
KYSE-520 CTRP2 -0.4307 3.5911 -0.5914 37.9811
OE21 CTRP2 -0.3609 2.3587 -0.3881 37.1297
TE-5 CTRP2 -0.2541 1.6738 -0.2576 36.3439
COLO 680N CTRP2 0.1041 3.1697 0.034 34.1786
KYSE-450 CTRP2; CTRP1 0.4514 2.6588 0.434 31.6987
TE-1 CTRP2 0.861 3.0071 0.8385 28.992
KYSE-30 CTRP2 1.3078 3.7075 1.2481 26.1467
OE33 CTRP2 1.3396 2.6694 1.3376 25.7408
KYSE-150 CTRP2 2.1715 6.0913 1.6173 22.1731
EC-GI-10 CTRP2 2.3956 4.4871 2.3013 19.0333
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 0.6158 3.1932 0.5699 30.7005
L3.3 CTRP2 -1.6262 2.8388 -1.7622 45.6799
PaTu 8988t CTRP2 -1.5461 1.1833 -1.5569 44.9494
TCC-Pan2 CTRP2 -1.1311 2.9292 -1.247 42.4451
SW1990 CTRP2 -0.5362 5.4008 -1.1143 39.6653
QGP-1 CTRP2; CTRP1 -0.5044 2.8641 -0.5764 38.2157
MIA PaCa-2 CTRP2 -0.3134 1.8997 -0.3217 36.7538
PaTu 8988s CTRP2 -0.0271 3.0761 -0.0948 35.0413
KP-3 CTRP2; CTRP1 0.2045 4.1238 0.0009 33.9362
BxPC-3 CTRP2 0.2218 2.5499 0.2029 33.23
Panc 10.05 CTRP2; CTRP1 0.4178 3.8276 0.2823 32.3105
PK-59 CTRP2 0.4677 2.7462 0.4465 31.6029
KP-4 CTRP2 0.5081 2.7964 0.4855 31.3389
SUIT-2 CTRP2; CTRP1 0.5514 3.9714 0.4026 31.4691
HuP-T4 CTRP2; CTRP1 0.5731 2.7791 0.5535 30.8966
Hs 766T CTRP2 0.6145 3.7799 0.5004 30.9363
DAN-G CTRP2 0.6355 3.814 0.5179 30.8086
PaTu 8902 CTRP2; CTRP1 0.7111 2.4133 0.7065 29.9292
Panc 08.13 CTRP2 0.7428 2.5872 0.7346 29.7301
PSN1 CTRP2 0.9157 4.9636 0.5884 29.6538
SU.86.86 CTRP2 0.9411 2.2311 0.9403 28.3868
Capan-1 CTRP2 0.9867 2.6992 0.9798 28.1043
HPAC CTRP2; CTRP1 1.1162 2.673 1.1118 27.2344
Panc 03.27 CTRP2; CTRP1 1.1469 3.4161 1.1073 27.1485
CFPAC-1 CTRP2; CTRP1 1.1622 3.6377 1.1019 27.1168
YAPC CTRP2 1.2168 2.6358 1.2141 26.56
SNU-213 CTRP2 1.3903 2.7996 1.387 25.4083
Panc 05.04 CTRP2 1.4298 2.6921 1.4282 25.1395
PK-45H CTRP2 1.4517 3.1201 1.441 25.0248
Capan-2 CTRP2; CTRP1 1.4666 3.8994 1.3937 25.1356
Panc 04.03 CTRP2 1.5264 3.1473 1.5165 24.5251
AsPC-1 CTRP2 1.5997 2.7256 1.5988 24.0075
KP-2 CTRP2 1.7192 2.3641 1.7192 23.2097
SNU-410 CTRP2 1.7614 4.3269 1.6455 23.3238
HuP-T3 CTRP2 1.9633 3.6657 1.9402 21.664
HPAF-II CTRP2 2.4474 5.3256 2.1626 19.3651
Panc 02.03 CTRP2 2.6095 4.1974 2.571 17.4192
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.4469 3.1492 1.435 25.0604
A101D CTRP2 -2.7023 4.1273 -3.1553 52.1847
K029AX CTRP2 -2.5237 1.6957 -2.591 51.3693
Mel Ho CTRP2 -2.4455 0.3517 -2.4517 50.9
MDA-MB-435S CTRP2 -2.0411 1.9999 -2.1111 48.2749
HMCB CTRP2 -1.9703 -0.1361 -1.9706 47.7456
Mel JuSo CTRP2 -1.5051 1.5585 -1.5276 44.7028
A-375 CTRP2; CTRP1 -1.3574 2.0353 -1.4007 43.7717
MeWo CTRP2 -1.1533 1.4638 -1.1646 42.3441
IPC-298 CTRP2 -1.1134 1.2394 -1.1192 42.0637
LOX-IMVI CTRP2 -1.0655 1.6353 -1.0803 41.7707
WM983B CTRP2 -0.9344 2.801 -1.0236 41.0965
A2058 CTRP2 -0.781 1.4203 -0.786 39.852
Hs 852.T CTRP2; CTRP1 -0.7088 1.2756 -0.7114 39.3645
COLO 741 CTRP1 -0.5573 2.4483 -0.5971 76.0085
IGR-1 CTRP2 -0.443 3.5894 -0.6044 38.0636
Hs 294T CTRP2 -0.3816 1.5866 -0.3851 37.1915
RPMI-7951 CTRP2 -0.3052 1.5893 -0.308 36.6814
WM88 CTRP2 -0.3052 3.5461 -0.4499 37.1125
SK-MEL-30 CTRP2 -0.2048 2.4947 -0.2344 36.0999
IGR-37 CTRP2 -0.191 1.5286 -0.1926 35.9179
Hs 936.T CTRP2; CTRP1 0.1885 2.8381 0.1516 33.5109
UACC-257 CTRP2 0.1979 2.6252 0.1744 33.4042
COLO 829 CTRP2 0.3123 7.8118 -1.0174 36.2805
COLO 800 CTRP2 0.3148 2.5334 0.299 32.6017
G-361 CTRP2; CTRP1 0.7169 2.6536 0.7062 29.911
SK-MEL-5 CTRP2; CTRP1 0.8109 3.3291 0.7626 29.4115
CJM [Human melanoma] CTRP2 0.9691 1.4312 0.9691 28.1982
SK-MEL-24 CTRP2 1.1518 2.0604 1.1518 26.983
Hs 944.T CTRP2; CTRP1 1.1671 2.632 1.164 26.8917
SK-MEL-1 CTRP2; CTRP1 1.2043 3.0988 1.1879 26.689
WM266-4 CTRP2 1.2268 2.5214 1.2254 26.489
WM1799 CTRP2 1.3044 2.7436 1.301 25.9799
WM793 CTRP2 1.337 2.6966 1.3346 25.7597
SK-MEL-3 CTRP2 1.4164 2.0481 1.4164 25.2237
SK-MEL-31 CTRP2 1.429 2.5083 1.4286 25.1412
Hs 688(A).T CTRP2 1.4365 3.4634 1.4061 25.1919
WM115 CTRP2 1.4407 2.4948 1.4403 25.0634
HT-144 CTRP2 1.4569 2.5104 1.4565 24.9559
IGR-39 CTRP2 1.4731 3.1239 1.4628 24.8809
COLO 792 CTRP2 1.5813 2.1211 1.5813 24.1271
RVH-421 CTRP2 1.6838 3.2528 1.6736 23.4795
Hs 940.T CTRP2 1.7167 2.4743 1.7166 23.2269
SK-MEL-28 CTRP2; CTRP1 1.7635 2.0508 1.7635 22.9155
SK-MEL-2 CTRP2 1.9577 2.5771 1.9577 21.6237
Hs 895.T CTRP2 2.6751 4.5814 2.5863 17.1562
UACC-62 CTRP2 2.7664 4.7659 2.65 16.6455
Hs 839.T CTRP2 3.3151 5.0502 3.1832 13.0542
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -0.9044 2.1891 -0.9405 40.7608
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 -3.8708 1.6271 -4.0002 59.3474
Kelly CTRP2 -2.137 -0.417 -2.1371 48.8535
SiMa CTRP2 -1.3657 1.8138 -1.3961 43.7982
SK-N-FI CTRP2 -1.0351 1.1299 -1.0386 41.5365
CHP-212 CTRP2 -0.894 0.8386 -0.8947 40.59
SK-N-DZ CTRP2 -0.7173 2.5232 -0.7694 39.5673
NB1 CTRP2 -0.649 1.2008 -0.6506 38.9638
KP-N-SI9s CTRP2 -0.4565 1.8257 -0.4654 37.7072
SK-N-AS CTRP2 -0.4121 2.4055 -0.4437 37.4832
NH-6 CTRP2 -0.2185 1.8636 -0.2247 36.1161
CHP-126 CTRP2 -0.2059 2.2289 -0.2225 36.0656
SK-N-SH CTRP2 -0.1576 1.9379 -0.1644 35.7128
SK-N-BE(2) CTRP2 0.2086 3.2664 0.134 33.4998
KP-N-YN CTRP2 3.4804 5.0217 3.3703 11.8786
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1196 CTRP2 -0.8362 2.3392 -0.8796 40.3294
SNU-308 CTRP2 0.5298 3.7534 0.4136 31.5051
SNU-478 CTRP2 0.631 2.1677 0.629 30.4533
SNU-1079 CTRP2 0.7035 2.5365 0.696 29.9894
HuCC-T1 CTRP2 1.0403 2.493 1.0378 27.7329
SNU-869 CTRP2 1.063 2.8081 1.0545 27.602
HuH-28 CTRP2 1.4564 2.3486 1.4563 24.9579
SNU-245 CTRP2 1.8741 3.8402 1.832 22.3215
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-ES-1 CTRP2 -2.8484 -1.3587 -2.8484 53.5838
CADO-ES1 CTRP2 -2.1853 -0.7175 -2.1853 49.1746
SK-N-MC CTRP2 -1.5009 1.6805 -1.5288 44.6859
TC71 CTRP2 -1.2151 1.1967 -1.2214 42.7409
SK-ES-1 CTRP2 -1.0372 0.3511 -1.0373 41.5401
A-673 CTRP2 -0.7288 0.7089 -0.729 39.4898
U2OS CTRP2; CTRP1 -0.7279 2.939 -0.8205 39.7477
SaOS-2 CTRP2 0.2374 2.1442 0.2318 33.0827
SW1353 CTRP2 0.2558 2.7837 0.2252 33.0429
SJSA-1 CTRP2 0.2751 1.8658 0.2735 35.3178
HOS CTRP2 0.3689 2.5305 0.3546 32.2369
CAL-78 CTRP2 0.9447 3.4955 0.8872 28.5532
Hs 888.T CTRP2 1.2647 3.8801 1.1811 26.5147
MG-63 CTRP2 1.4749 3.9253 1.3991 25.0905
G-292 clone A141B1 CTRP2 1.9639 4.2942 1.8688 21.9061
Hs 822.T CTRP2 2.2773 3.2035 2.2765 19.5016
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 73 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-468 CTRP2 -3.024 -0.5353 -3.0256 54.7389
HCC1806 CTRP2 -1.3306 1.7544 -1.357 43.5571
AU565 CTRP2 -1.1831 2.0084 -1.2183 42.6029
MDA-MB-157 CTRP2 -0.9859 4.6719 -1.4128 42.1333
JIMT-1 CTRP2 -0.4534 3.2979 -0.573 38.0154
CAL-51 CTRP2 -0.4398 2.2607 -0.4643 37.645
HCC1954 CTRP2 -0.2389 2.3939 -0.264 36.3126
CAL-148 CTRP2 -0.1945 1.0422 -0.1945 35.9359
HCC1143 CTRP2 -0.1597 3.9172 -0.3546 36.3025
MCF-7 CTRP2; CTRP1 -0.1423 3.5498 -0.2759 36.0068
SK-BR-3 CTRP2 -0.1061 2.1272 -0.1169 35.3834
DU4475 CTRP2 -0.0342 0.6765 -0.0342 34.8697
HCC1395 CTRP2 0.1269 2.5961 0.1027 33.8785
HMC-1-8 CTRP2 0.1541 2.9005 0.1111 33.7591
CAL-85-1 CTRP2 0.2308 2.6013 0.2096 33.1781
MDA-MB-231 CTRP2 0.5858 3.7553 0.4733 31.1215
ZR-75-1 CTRP2 0.6197 3.207 0.5728 30.678
CAMA-1 CTRP2 0.7206 3.3331 0.6672 30.0291
HCC1428 CTRP2 0.7328 1.9069 0.7325 29.7705
BT-474 CTRP2 0.7411 2.9536 0.7175 29.7931
HCC1569 CTRP2 0.9091 3.4046 0.8587 28.766
HCC1937 CTRP2 0.935 3.1453 0.9067 28.5194
Hs 578T CTRP2 0.9632 3.0356 0.9425 28.3063
EFM-192A CTRP2 1.002 2.456 0.9997 27.9873
HCC1500 CTRP2 1.0765 3.2239 1.0484 27.578
HCC38 CTRP2 1.0907 2.8933 1.08 27.4253
MDA-MB-453 CTRP2 1.107 2.9667 1.0938 27.325
HDQ-P1 CTRP2 1.1148 5.8461 0.5521 29.1333
HCC202 CTRP2 1.1696 2.3769 1.1689 26.867
ZR-75-30 CTRP2 1.5014 2.8712 1.4981 24.6695
HCC1419 CTRP2 1.5352 2.5298 1.5349 24.4346
KPL-1 CTRP2 1.5631 1.9253 1.5631 24.2483
MDA-MB-415 CTRP2 1.6061 2.5422 1.6059 23.9629
T-47D CTRP2 1.6922 3.3939 1.6759 23.4441
Hs 578Bst CTRP2 1.9437 3.0336 1.9423 21.7218
CAL-120 CTRP2 2.1019 4.4016 1.9996 21.0136
MDA-MB-361 CTRP2 2.1236 3.9115 2.0877 20.6415
BT-20 CTRP2 2.1278 4.3605 2.0343 20.811
BT-549 CTRP2 2.9608 4.6742 2.8781 15.2358
BT 416 CTRP2 -0.2473 1.8599 -0.2538 36.3086
BT 271 CTRP2 -0.1449 3.1748 -0.2298 35.8757
BT 428 CTRP2 0.4662 3.9777 0.3098 32.0583
BT 330 CTRP2 0.509 2.5928 0.4957 31.3021
BT 245 CTRP2 0.6641 2.4713 0.6576 30.2481
BT 131 CTRP2 0.7669 2.7582 0.7536 29.5871
BT 231 CTRP2 0.7747 3.4821 0.7091 29.7102
BT 239 CTRP2 0.8278 2.4045 0.8246 29.1481
BT 286 CTRP2 1.0193 2.5598 1.0157 27.8761
BT 145 CTRP2 1.1068 1.7831 1.1068 27.2823
BT 504 CTRP2 1.1318 3.3102 1.0999 27.2232
BT 248 CTRP2 1.176 2.6863 1.1721 26.8354
BT 179 CTRP2 1.1831 1.9891 1.1831 26.7748
BT164 CTRP2 1.1974 1.8894 1.1974 26.6797
BT 112 CTRP2 1.2093 1.9687 1.2093 26.6005
BT147 CTRP2 1.2269 4.1074 1.1069 26.8902
BT 159 CTRP2 1.2544 2.758 1.2502 26.3151
BT 172 CTRP2 1.2588 3.5855 1.2092 26.4381
BT 224 CTRP2 1.3514 2.1214 1.3514 25.6561
BT 228 CTRP2 1.4583 3.3714 1.4352 25.0222
BT 359 CTRP2 1.506 3.5404 1.4727 24.7397
BT 482 CTRP2 1.5137 3.3911 1.4914 24.6512
BT 440 CTRP2 1.6435 2.1163 1.6435 23.7134
BT 216 CTRP2 1.6455 2.9357 1.6428 23.7088
BT 187 CTRP2 1.9059 3.8202 1.8674 22.098
BT 232 CTRP2 1.9074 3.4946 1.8926 22.0078
BT 422 CTRP2 2.2595 3.1048 2.2592 19.618
BT 333 CTRP2 2.4326 3.144 2.4325 18.4663
BT 340 CTRP2 2.4893 3.1184 2.4893 18.0887
BT 139 CTRP2 2.5535 3.7145 2.5466 17.685
BT 328 CTRP2 2.5855 3.1073 2.5855 17.4488
BT 320 CTRP2 2.6762 3.2137 2.6761 16.8463
BT 498 CTRP2 6.2788 8.3706 4.4061 1.7826
BT 444 CTRP2 6.7892 8.1521 4.7556 0.3111
⏷ Show the Full List of 73 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.0175 1.6604 0.0161 34.5309
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-42 CTRP2 -1.7937 3.5118 -2.0457 46.864
GB-1 CTRP2 -1.4052 0.6669 -1.4068 43.9915
LN-18 CTRP2 -1.3227 0.5688 -1.3236 43.4413
LN-229 CTRP2; CTRP1 -0.5199 2.2827 -0.5481 38.1882
GMS-10 CTRP2 -0.3957 2.1519 -0.414 37.3329
KNS-60 CTRP2 -0.3555 1.6122 -0.359 37.018
SNU-738 CTRP2 -0.3096 3.2383 -0.4121 37.0181
D283 Med CTRP2 -0.2328 2.1447 -0.2468 36.2363
Hs 683 CTRP2 -0.1284 1.3224 -0.1288 35.4977
U-87MG ATCC CTRP2 -0.1089 2.5883 -0.1407 35.4703
U-118MG CTRP2 0.0238 3.9033 -0.1542 35.047
Daoy CTRP2 0.1002 2.4053 0.0842 34.0288
SF295 CTRP2; CTRP1 0.1488 2.925 0.1036 33.8018
SF126 CTRP2 0.1694 3.3865 0.0785 33.8125
42-MG-BA CTRP2 0.1811 2.7011 0.1528 33.5316
KALS-1 CTRP2 0.2215 4.6577 -0.0939 34.167
SF268 CTRP2 0.2573 1.7257 0.2565 32.9341
SNB-75 CTRP2 0.4234 3.8088 0.2913 32.2625
YKG-1 CTRP2 0.4429 2.3649 0.4354 31.7223
CAS-1 CTRP2 0.508 6.1826 -0.2167 33.5314
SF539 CTRP2 0.609 2.0876 0.6075 30.5979
SW1088 CTRP2 0.7112 3.2036 0.669 30.054
YH-13 CTRP2 0.7767 1.8594 0.7766 29.4778
GOS-3 CTRP2 0.8907 2.4938 0.8868 28.7323
ONS-76 CTRP2 0.9814 2.3745 0.9798 28.1217
GaMG CTRP2; CTRP1 0.9975 1.9048 0.9974 28.0095
SNU-1105 CTRP2 1.0131 3.2248 0.9825 28.0079
A-172 CTRP2 1.0774 2.0007 1.0773 27.4781
DK-MG CTRP2 1.1823 2.1947 1.1822 26.7806
KNS-81 CTRP2 1.3349 2.6966 1.3325 27.7363
M059K CTRP2 1.4191 2.7324 1.417 25.2128
SNU-466 CTRP2 1.4202 2.9581 1.414 25.2187
NMC-G1 CTRP2 1.466 2.5395 1.4656 24.895
Becker CTRP2 1.4974 3.8176 1.4364 24.8904
T98G CTRP2 1.6539 3.9119 1.5912 23.8558
DBTRG-05MG CTRP2 1.7638 4.1903 1.6703 23.2308
U-251MG CTRP2 1.7811 3.6194 1.7538 22.8898
8-MG-BA CTRP2 1.9341 3.4731 1.9212 21.8239
KG-1-C CTRP2 1.9716 3.8793 1.9309 21.6685
CCF-STTG1 CTRP2 2.0784 3.2024 2.0761 20.829
SNU-489 CTRP2 2.0865 5.1548 1.8161 21.7081
TM-31 CTRP2 2.5873 3.5953 2.5843 17.447
SNU-626 CTRP2 2.7703 6.1223 2.2523 18.0856
SNU-201 CTRP2 3.5481 4.0917 3.5475 11.0497
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 CTRP2 -2.7229 -0.3178 -2.7245 52.7441
JHUEM-2 CTRP2; CTRP1 -2.2626 1.5179 -2.3067 49.6963
HEC-1-B CTRP2 -1.2399 1.7498 -1.2634 42.9499
HEC-151 CTRP2; CTRP1 -0.9644 1.8202 -0.9837 41.1125
HEC-108 CTRP2; CTRP1 -0.3435 2.2294 -0.3638 36.9921
AN3-CA CTRP2 -0.3315 2.1581 -0.3484 36.9019
KLE CTRP2; CTRP1 -0.2044 4.5405 -0.5305 36.9613
MFE-296 CTRP2 -0.0163 3.1949 -0.0959 35.0076
HEC-50B CTRP2 0.0029 5.2565 -0.4855 36.0716
EN CTRP2 0.0144 3.4491 -0.0943 34.8954
MFE-319 CTRP2; CTRP1 0.0257 2.4747 0.0046 34.5411
JHUEM-1 CTRP2 0.2744 1.5698 0.2741 32.8188
HEC-1-A CTRP2 0.3464 2.8056 0.3177 32.4341
JHUEM-7 CTRP2 0.5502 2.8929 0.5236 31.0723
HEC-6 CTRP2; CTRP1 0.5881 2.5512 0.578 30.7652
HEC-251 CTRP2; CTRP1 0.966 3.6725 0.8899 28.4744
HEC-265 CTRP2; CTRP1 1.1527 2.7405 1.1474 26.9948
EFE-184 CTRP2 1.3677 3.1603 1.3531 25.5963
HEC-59 CTRP2; CTRP1 1.3972 4.7097 1.1741 26.1145
JHUEM-3 CTRP2 1.5373 4.138 1.4354 24.765
ESS-1 CTRP2 1.8564 3.289 1.8488 22.3232
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -1.4858 -0.2458 -1.4858 44.5229
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 -1.1772 12.4904 -4.5375 45.9411
769-P CTRP2 -0.9452 2.7067 -1.0252 41.1448
BFTC-909 CTRP2 0.1239 1.8902 0.1211 33.828
786-O CTRP2 0.4202 3.1828 0.3657 32.0289
KMRC-20 CTRP2 0.5238 3.1556 0.4768 31.3154
VMRC-RCZ CTRP2 0.6602 2.6516 0.6483 30.2917
OS-RC-2 CTRP2 0.9939 4.0477 0.8661 28.4638
ACHN CTRP2 1.1459 3.1348 1.1258 27.0897
VMRC-RCW CTRP2; CTRP1 1.166 3.3126 1.1353 26.9914
KMRC-3 CTRP2 1.168 2.3696 1.1673 26.8779
TUHR4TKB CTRP2 1.1809 2.8925 1.1721 26.819
CAL-54 CTRP2 1.1932 3.3288 1.1625 26.8107
TUHR10TKB CTRP2 1.5451 2.2455 1.5451 24.3677
KMRC-2 CTRP2 1.7612 2.3314 1.7612 22.9308
TUHR14TKB CTRP2 2.2007 4.3465 2.1149 20.2993
KMRC-1 CTRP2 2.292 3.7674 2.2748 19.4581
A-498 CTRP2 2.2947 4.6841 2.155 19.862
RCC10RGB CTRP2; CTRP1 2.4664 3.8703 2.4492 18.2988
SNU-1272 CTRP2 2.824 8.9057 1.1291 22.1589
Caki-1 CTRP2 2.8613 4.3444 2.8208 15.7517
Caki-2 CTRP2 3.4159 4.7478 3.3561 12.1309
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1040 CTRP1 -3.6937 3.9628 -4.197 80.98
SNU-175 CTRP1 -3.1675 0.6439 -3.195 90.9534
HCT 15 CTRP2 -2.5212 1.7179 -2.5901 51.3519
SW48 CTRP2; CTRP1 -2.4382 0.1713 -2.442 50.8535
COLO201 CTRP2 -2.0285 2.154 -2.1117 48.2029
HT115 CTRP2; CTRP1 -1.8155 0.0253 -1.8159 46.7165
RKO CTRP2; CTRP1 -1.7861 2.2398 -1.8649 46.6344
NCI-H716 CTRP2 -1.5579 3.9776 -1.8797 45.4895
CL-34 CTRP2; CTRP1 -1.3243 2.4244 -1.3968 46.865
SNU-81 CTRP2; CTRP1 -1.1559 2.6954 -1.2464 42.5516
HCT 8 CTRP2; CTRP1 -1.1433 2.2408 -1.1923 42.3733
NCI-H508 CTRP2; CTRP1 -0.9946 2.414 -1.0505 41.4096
LS411N CTRP2; CTRP1 -0.892 2.7198 -0.9704 40.7904
LS180 CTRP2; CTRP1 -0.6588 2.0802 -0.6811 39.0926
T84 CTRP2 -0.5262 1.2022 -0.5272 38.1451
SK-CO-1 CTRP2; CTRP1 -0.4821 2.6387 -0.5329 38.0058
LoVo CTRP2; CTRP1 -0.3537 2.6447 -0.3992 37.1385
GP2d CTRP2; CTRP1 -0.2776 1.7233 -0.282 36.5033
SNU-407 CTRP2 -0.191 3.2493 -0.2875 36.2163
SW1417 CTRP2 -0.1908 3.3586 -0.3011 36.2568
SNU-C5 CTRP2; CTRP1 -0.1403 2.926 -0.1994 35.7653
CL-40 CTRP1 -0.0843 2.6103 -0.1166 71.9651
COLO205 CTRP2; CTRP1 -0.0701 1.5467 -0.0713 35.1127
SNU-C2A CTRP2; CTRP1 -0.0508 3.9841 -0.2491 35.5981
CCK-81 CTRP2 0.0078 2.9836 -0.0492 34.7759
HT-55 CTRP2; CTRP1 0.0512 2.2527 0.0396 34.3404
SW948 CTRP2; CTRP1 0.2148 2.7166 0.1869 33.3064
LS513 CTRP2; CTRP1 0.2941 1.5924 0.2938 32.6879
DLD-1 CTRP2; CTRP1 0.3013 2.8467 0.2683 32.7479
OUMS-23 CTRP2 0.3297 2.3901 0.3195 32.4841
KM12 CTRP2; CTRP1 0.3772 3.4758 0.2884 32.4275
CW-2 CTRP2; CTRP1 0.4913 3.185 0.4401 31.5459
MDST8 CTRP2; CTRP1 0.4947 2.9282 0.4637 31.456
SNU-61 CTRP2; CTRP1 0.5623 3.1724 0.5157 31.0585
SNU-C4 CTRP2; CTRP1 0.6168 2.2028 0.6143 30.5493
CL-11 CTRP2 0.624 3.0527 0.5897 30.6073
RCM-1 [Human ESC] CTRP2; CTRP1 0.6778 1.9669 0.6773 30.1371
SNU-C1 CTRP2 0.6831 2.5483 0.6749 30.1271
SW620 CTRP2; CTRP1 0.7217 4.2587 0.5348 30.4678
LS1034 CTRP2 0.7631 1.3584 0.7631 29.5678
HCT 116 CTRP2; CTRP1 0.9199 3.5549 0.8546 28.7444
COLO 320 CTRP2; CTRP1 1.0286 5.0789 0.6817 28.9761
C2BBe1 CTRP2; CTRP1 1.1153 2.9798 1.1018 27.2709
LS123 CTRP2; CTRP1 1.1842 3.9721 1.0821 27.1128
COLO 678 CTRP2; CTRP1 1.2018 3.1814 1.181 26.7201
NCI-H747 CTRP2 1.2652 2.9653 1.2558 26.2604
SW1116 CTRP2 1.3186 3.1657 1.3023 25.9282
SNU-1033 CTRP2 1.5466 2.8951 1.5435 24.3679
HCC-56 CTRP2 1.6121 2.2305 1.6121 23.9224
HT-29 CTRP2; CTRP1 1.8285 3.7739 1.7905 22.6109
SW403 CTRP1 2.0143 4.0986 1.9511 45.8583
SW480 CTRP1 2.2557 4.8003 2.0878 42.9438
SNU-503 CTRP2 2.8424 5.0175 2.6761 16.3169
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2 CTRP2; CTRP1 -0.9306 4.8016 -1.3846 41.8423
SNU-878 CTRP2 -0.8256 1.901 -0.8446 40.1902
SNU-182 CTRP2 -0.8204 1.652 -0.8309 40.1307
JHH-4 CTRP2 -0.4196 2.2026 -0.4408 37.5005
Li-7 CTRP2 -0.4061 2.9575 -0.4823 37.5782
HuH-6 CTRP2 -0.2564 2.4586 -0.2857 42.1197
HuH-1 CTRP2 -0.1079 4.3018 -0.3733 36.167
Hep 3B2.1-7 CTRP2 -0.0945 2.6615 -0.1305 35.3882
JHH-1 CTRP2 -0.0196 2.7739 -0.0605 34.9062
SNU-398 CTRP2; CTRP1 0.2166 2.7264 0.1881 33.2964
HLF CTRP2 0.2411 1.6047 0.2407 33.0405
SK-HEP-1 CTRP2 0.4754 2.5287 0.4637 31.5202
JHH-5 CTRP2 0.5702 3.0157 0.5362 30.964
SNU-449 CTRP2; CTRP1 1.1605 2.8213 1.1534 26.9489
SNU-761 CTRP2 1.1869 2.6467 1.1838 26.7598
SNU-475 CTRP2 1.3862 2.2955 1.3861 25.425
PLC/PRF/5 CTRP2 1.4485 3.5778 1.4094 25.1414
SNU-886 CTRP2 1.5267 2.85 1.524 24.499
SNU-423 CTRP2 1.6672 3.036 1.663 23.57
JHH-6 CTRP2; CTRP1 1.9129 3.5052 1.8977 21.9728
SNU-387 CTRP2 1.9974 3.8874 1.9573 21.4949
JHH-2 CTRP2 2.081 3.4421 2.0731 20.8306
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 161 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1341 CTRP2 -5.0716 0.3603 -5.1477 66.3827
NCI-H82 CTRP1 -3.2969 2.7976 -3.5439 83.6535
NCI-H1876 CTRP1 -3.1057 2.6699 -3.3191 83.7577
SHP-77 CTRP2; CTRP1 -2.8649 0.0025 -2.8703 53.6702
Calu-6 CTRP2; CTRP1 -2.7933 1.5365 -2.8601 53.0778
NCI-H596 CTRP1 -2.4285 1.5776 -2.483 86.4981
NCI-H1963 CTRP1 -2.3916 1.3589 -2.4309 87.2971
SCLC-21H CTRP1 -2.25 0.2553 -2.2533 91.6863
NCI-H1930 CTRP1 -2.1886 2.7151 -2.3452 81.7542
NCI-H2141 CTRP1 -2.143 3.3536 -2.3946 79.5003
NCI-H526 CTRP2 -1.898 1.4629 -1.927 47.3042
NCI-H1437 CTRP1 -1.8534 1.6685 -1.8921 84.8487
NCI-H2073 CTRP1 -1.7522 6.0838 -2.6436 71.1755
LC-1F CTRP2 -1.7317 5.1025 -2.3368 46.7903
A-549 CTRP2; CTRP1 -1.6392 1.8254 -1.6797 45.6205
ChaGo-K-1 CTRP2; CTRP1 -1.4709 3.2329 -1.652 44.7545
NCI-H1651 CTRP2 -1.3425 2.9028 -1.4684 43.8376
NCI-H889 CTRP2 -1.3399 2.0742 -1.3851 43.6603
NCI-H1781 CTRP1 -1.3136 2.009 -1.3535 81.6392
NCI-H520 CTRP2 -1.3026 1.9233 -1.337 43.3906
VMRC-LCD CTRP2; CTRP1 -1.1981 3.2876 -1.3678 42.9891
COLO 668 CTRP2; CTRP1 -1.1217 2.5336 -1.1941 42.2864
NCI-H1573 CTRP2; CTRP1 -1.0516 4.2845 -1.3948 42.3877
LCLC-97TM1 CTRP2; CTRP1 -1.0338 1.8126 -1.0545 41.5765
NCI-H1299 CTRP2; CTRP1 -0.991 2.3956 -1.0452 41.3814
Lu-99 CTRP2; CTRP1 -0.9768 1.714 -0.9923 41.1839
EKVX CTRP2 -0.9617 7.6443 -2.3179 43.3594
HCC95 CTRP2 -0.9093 2.5373 -0.9715 40.8625
NCI-H1694 CTRP2; CTRP1 -0.8956 2.9302 -0.9971 40.8723
NCI-H211 CTRP2 -0.8945 1.5913 -0.9047 40.6219
HCC15 CTRP2; CTRP1 -0.8795 2.8177 -0.9675 40.7329
NCI-H1184 CTRP2 -0.7577 2.0851 -0.7831 39.7584
HCC44 CTRP2; CTRP1 -0.7501 1.6928 -0.7605 39.6634
NCI-H2405 CTRP2; CTRP1 -0.6898 3.4352 -0.8453 39.6619
NCI-H1048 CTRP1 -0.6112 1.195 -0.6126 80.6502
EBC-1 CTRP2; CTRP1 -0.6064 2.1627 -0.6312 38.7524
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 -0.5988 3.2877 -0.7267 38.9939
NCI-H727 CTRP2; CTRP1 -0.5779 2.4483 -0.6185 38.6106
HCC1438 CTRP2 -0.5768 2.4306 -0.6162 38.5997
HCC2108 CTRP2; CTRP1 -0.5678 2.6981 -0.6275 38.5994
NCI-H1792 CTRP2; CTRP1 -0.5462 2.8009 -0.6143 38.4807
NCI-H292 CTRP2 -0.4898 3.4093 -0.6274 38.305
COR-L23 CTRP1 -0.468 2.0591 -0.4844 76.7035
NCI-H446 CTRP2 -0.4506 2.1831 -0.4717 37.7063
NCI-H1155 CTRP2 -0.4263 1.5648 -0.4299 37.4893
KNS-62 CTRP2; CTRP1 -0.418 1.5577 -0.4214 37.4332
DV-90 CTRP2; CTRP1 -0.4177 3.9788 -0.6447 38.076
NCI-H69 CTRP2 -0.4083 1.694 -0.4137 37.3752
NCI-H522 CTRP2; CTRP1 -0.3716 1.6232 -0.3755 37.1262
RERF-LC-MS CTRP2 -0.3532 2.8487 -0.4159 37.1875
NCI-H460 CTRP2; CTRP1 -0.3368 5.5582 -0.942 38.4964
NCI-H1975 CTRP2; CTRP1 -0.3276 2.0157 -0.3394 36.8594
NCI-H1339 CTRP2 -0.2791 2.5733 -0.3165 36.6182
NCI-H2122 CTRP2; CTRP1 -0.2658 3.0348 -0.3423 36.6508
Lu-65 CTRP2; CTRP1 -0.2641 2.4691 -0.2943 36.4962
CAL-12T CTRP2; CTRP1 -0.1841 3.4093 -0.3008 36.2319
LK2 CTRP2 -0.1556 1.1391 -0.1557 35.6776
HCC366 CTRP2 -0.1136 3.4588 -0.2322 35.7722
NCI-H2009 CTRP2; CTRP1 -0.0987 3.131 -0.1761 35.5465
NCI-H322 CTRP2 -0.0593 3.3489 -0.1599 35.3577
RERF-LC-A1 CTRP2 -0.0469 1.8206 -0.0504 34.9658
SK-LU-1 CTRP2; CTRP1 -0.0454 3.243 -0.1322 35.2226
NCI-H23 CTRP2; CTRP1 -0.0222 1.2909 -0.0224 34.7911
HCC1359 CTRP1 -0.0024 1.9762 -0.0079 72.8396
DMS 454 CTRP2 0.0277 3.6537 -0.1093 34.8956
HCC1833 CTRP2; CTRP1 0.0447 4.7032 -0.2972 35.3947
NCI-H1836 CTRP1 0.0504 2.4646 0.0305 71.1501
NCI-H1105 CTRP2; CTRP1 0.0558 2.8121 0.0152 34.4045
NCI-H2342 CTRP2; CTRP1 0.0591 2.4007 0.0422 34.3052
NCI-H2286 CTRP2; CTRP1 0.0625 2.694 0.0304 34.3323
DMS 114 CTRP2 0.0697 1.9861 0.0649 34.195
NCI-H1355 CTRP2; CTRP1 0.1334 3.7938 -0.0178 34.2414
NCI-H1092 CTRP2 0.1357 5.0338 -0.2807 35.0203
MOR/CPR CTRP2 0.1497 2.5423 0.129 33.7155
NCI-H1734 CTRP2 0.1795 3.074 0.1228 33.6351
DMS 79 CTRP2 0.1798 3.2556 0.1048 33.6924
COR-L51 CTRP2; CTRP1 0.1901 1.8336 0.1883 33.3843
NCI-H810 CTRP2; CTRP1 0.2053 1.6084 0.2048 33.2791
NCI-H2087 CTRP2 0.2151 3.3269 0.1341 33.4774
BEN CTRP2; CTRP1 0.2255 3.1334 0.1656 33.34
NCI-H2170 CTRP2 0.2437 5.1781 -0.2013 34.4071
NCI-H1703 CTRP2 0.2534 3.3768 0.1689 33.2349
COLO 699 CTRP2; CTRP1 0.2551 2.7432 0.227 33.039
NCI-H2228 CTRP2 0.2621 3.7294 0.1304 35.849
NCI-H841 CTRP2; CTRP1 0.2837 2.3033 0.2751 32.7845
NCI-H358 CTRP2; CTRP1 0.2868 3.5914 0.1769 33.0956
DMS 273 CTRP2; CTRP1 0.3051 2.5815 0.2871 32.6733
NCI-H2171 CTRP2 0.3107 1.628 0.3103 32.5777
SK-MES-1 CTRP2 0.4074 3.1183 0.358 32.0971
NCI-H1373 CTRP2; CTRP1 0.4131 2.728 0.3912 31.9682
HCC33 CTRP1 0.4346 2.3188 0.428 67.3745
NCI-H661 CTRP2; CTRP1 0.4624 4.0559 0.2921 32.1285
NCI-H1581 CTRP2 0.4681 2.1045 0.4656 31.5381
DMS 53 CTRP2 0.4719 2.8904 0.4425 31.6021
NCI-H2106 CTRP2 0.4724 3.0928 0.4283 31.6476
HCC1588 CTRP2 0.4902 1.8845 0.4894 31.3853
NCI-H2081 CTRP2; CTRP1 0.5335 2.7733 0.5129 31.1633
NCI-H2023 CTRP2; CTRP1 0.5718 4.8054 0.2526 31.8874
NCI-H2110 CTRP2; CTRP1 0.5818 6.6321 -0.2902 33.4885
NCI-H1944 CTRP2; CTRP1 0.5958 3.0223 0.5624 30.7916
NCI-H2085 CTRP2 0.5982 3.2419 0.5472 30.8344
PC-14 CTRP2 0.5988 3.4829 0.5227 33.2643
NCI-H2126 CTRP2; CTRP1 0.6172 3.9878 0.4707 31.0258
NCI-H1650 CTRP2 0.6213 3.305 0.5655 30.6971
NCI-H1568 CTRP2; CTRP1 0.6561 1.9877 0.6554 30.2819
NCI-H650 CTRP2; CTRP1 0.664 2.8006 0.646 30.2871
EPLC-272H CTRP2; CTRP1 0.6954 3.7919 0.5852 30.3863
HCC2935 CTRP2; CTRP1 0.7516 2.7943 0.7364 29.695
NCI-H146 CTRP2 0.7961 3.0345 0.7697 29.4367
HCC2279 CTRP2 0.8065 4.1439 0.6477 29.8121
NCI-H1838 CTRP2 0.8077 2.9051 0.7889 29.3339
NCI-H1666 CTRP2; CTRP1 0.8147 2.6968 0.8046 29.2584
LXF 289 CTRP2; CTRP1 0.8305 2.5782 0.824 29.1415
NCI-H2029 CTRP2; CTRP1 0.8729 2.1708 0.8721 28.8403
LUDLU-1 CTRP2 0.902 4.3292 0.7164 29.2693
NCI-H441 CTRP2; CTRP1 0.9951 3.2419 0.9625 28.1343
LCLC-103H CTRP2; CTRP1 1.0328 3.0817 1.0118 27.8447
NCI-H1793 CTRP2; CTRP1 1.0718 3.8346 0.9815 27.8195
NCI-H1623 CTRP2 1.1001 3.3544 1.0634 27.45
SW1271 CTRP2 1.1205 2.7229 1.1152 29.2809
NCI-H196 CTRP2 1.1224 3.4843 1.0754 27.3365
NCI-H1693 CTRP2 1.1617 2.2326 1.1615 26.918
HCC78 CTRP2; CTRP1 1.1726 3.1419 1.153 26.9103
NCI-H1755 CTRP2; CTRP1 1.183 3.2608 1.1566 26.8638
NCI-H1435 CTRP2; CTRP1 1.2299 2.5652 1.2281 26.4698
Calu-3 CTRP2; CTRP1 1.2301 2.9353 1.2209 26.4932
COR-L95 CTRP2 1.2376 2.1674 1.2375 26.413
NCI-H2196 CTRP2 1.2566 2.536 1.2553 26.2905
Sq-1 CTRP2; CTRP1 1.2744 2.7228 1.2711 26.1789
NCI-H2291 CTRP2 1.2976 2.829 1.2926 26.0302
NCI-H2030 CTRP2; CTRP1 1.3123 4.2738 1.1704 26.3978
RERF-LC-KJ CTRP1 1.3412 3.4246 1.3097 54.996
RERF-LC-Ad2 CTRP2 1.3926 2.2695 1.3926 25.3817
NCI-H1869 CTRP2 1.4628 2.5914 1.4621 24.9174
LOU-NH91 CTRP2 1.474 3.0464 1.4663 24.8661
NCI-H647 CTRP2 1.4803 3.9045 1.4076 25.044
HCC1195 CTRP2; CTRP1 1.506 4.1686 1.397 24.9977
LC-1/sq-SF CTRP2; CTRP1 1.5678 3.2569 1.5545 24.2612
HOP-92 CTRP2 1.6018 4.1763 1.4987 24.3404
COR-L88 CTRP1 1.6185 3.2201 1.608 51.2755
HCC827 CTRP2; CTRP1 1.6441 5.1116 1.3447 24.7447
COR-L279 CTRP2; CTRP1 1.6993 4.5881 1.5287 50.1244
NCI-H3255 CTRP1 1.7307 2.7254 1.7303 49.6967
RERF-LC-Ad1 CTRP2 1.8547 2.3177 1.8547 22.3092
HOP-62 CTRP2 1.9229 4.0074 1.8653 22.0501
Calu-1 CTRP2 1.9341 3.3363 1.9267 21.8055
NCI-H1915 CTRP2; CTRP1 1.939 4.4951 1.8069 22.2
T3M-10 CTRP2; CTRP1 1.9636 3.4452 1.9527 21.6211
SBC-5 CTRP2 1.9924 4.4295 1.8766 21.7879
HCC4006 CTRP2; CTRP1 2.0072 3.174 2.0046 21.3034
HCC1171 CTRP2 2.2184 4.5654 2.0958 20.3093
SW1573 CTRP2 2.2741 6.5119 1.5754 22.0283
NCI-H838 CTRP2 2.3537 3.9339 2.3271 19.0798
NCI-H226 CTRP2 2.5455 5.2137 2.301 19.982
NCI-H1563 CTRP2 2.7693 3.5085 2.7688 16.2287
NCI-H1395 CTRP2 2.8717 5.0386 2.7027 16.132
COR-L105 CTRP2 2.9704 4.602 2.9009 15.1262
NCI-H2172 CTRP2; CTRP1 3.2647 4.9734 3.1466 13.3401
IA-LM CTRP2 3.5386 4.9683 3.4457 11.431
NCI-H2444 CTRP2 6.546 7.749 4.8066 0.3039
Hs 888.Lu CTRP2 2.354 4.434 2.2655 19.2898
⏷ Show the Full List of 161 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 -0.4215 1.9015 -0.4318 37.4789
H-STS CTRP2 0.4145 1.1041 0.4145 31.8861
P-STS CTRP2 1.1072 2.2847 1.1067 27.2814
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.3583 3.1754 -0.4562 37.326
TOV-112D CTRP2 -2.7532 3.6751 -3.1148 52.5305
A2780 CTRP2; CTRP1 -1.7953 1.8382 -1.8425 46.6542
RMUG-S CTRP1 -1.6896 1.605 -1.7194 84.6332
COV434 CTRP2; CTRP1 -1.6814 0.1994 -1.682 45.8252
OVCAR-8 CTRP2; CTRP1 -1.4252 -0.0306 -1.4252 44.1198
OVKATE CTRP1 -1.3467 2.2185 -1.4028 80.9503
SNU-119 CTRP2 -1.3167 2.2203 -1.3716 43.5285
JHOS-4 CTRP1 -1.2589 2.3872 -1.3249 79.9425
OVK18 CTRP2; CTRP1 -1.091 1.5101 -1.1025 41.9309
OVCAR-4 CTRP2; CTRP1 -1.0364 2.0851 -1.071 41.6308
ES2 CTRP2 -0.5673 2.3953 -0.6039 38.5283
SNU-8 CTRP2 -0.2478 2.3576 -0.2713 36.3664
Caov-3 CTRP2; CTRP1 -0.2211 3.2249 -0.3165 36.4119
OC 314 CTRP2 -0.133 1.4028 -0.1337 35.5292
TYK-nu CTRP2; CTRP1 -0.076 2.2764 -0.0912 35.1979
ONCO-DG-1 CTRP2 0.1015 2.4069 0.0855 34.0203
IGROV-1 CTRP2; CTRP1 0.1787 4.1073 -0.0239 34.1032
OV-90 CTRP2; CTRP1 0.2945 4.4337 0.0357 33.5162
JHOC-5 CTRP2; CTRP1 0.7904 2.8909 0.7718 29.4486
OVCAR-5 CTRP2 0.7984 3.5674 0.7245 29.5807
HEY A8 CTRP2; CTRP1 0.8444 3.3882 0.7922 29.2023
COV362 CTRP2; CTRP1 0.8595 4.3402 0.6681 29.5701
OVMANA CTRP1 0.871 3.6283 0.7943 60.5018
MCAS CTRP2 0.9462 2.4571 0.9434 28.3595
RMG-I CTRP2; CTRP1 1.0075 2.9646 0.9917 27.9956
COV644 CTRP2; CTRP1 1.0222 2.8491 1.0115 27.8807
DOV13 CTRP2 1.0362 3.7596 0.9536 28.0298
OVSAHO CTRP2 1.1066 3.0723 1.0885 27.344
OV7 CTRP2; CTRP1 1.1132 3.018 1.098 27.2904
OVTOKO CTRP2 1.193 4.4492 1.0079 27.3382
OAW28 CTRP2 1.2795 3.6622 1.2231 26.3238
SK-OV-3 CTRP2; CTRP1 1.4123 3.2856 1.3927 25.3165
OAW42 CTRP2; CTRP1 1.4938 3.9718 1.4131 24.9817
SNU-840 CTRP2; CTRP1 1.5099 3.4704 1.4821 24.6951
OVISE CTRP2 1.5372 4.4356 1.3835 24.9447
Kuramochi CTRP2 1.8451 3.8328 1.8023 22.5166
OV56 CTRP2 2.3539 3.8988 2.3301 19.0691
EFO-27 CTRP2; CTRP1 2.4141 4.67 2.2873 19.0236
JHOS-2 CTRP2 2.4167 3.442 2.4143 18.5797
EFO-21 CTRP2; CTRP1 2.4206 4.9739 2.2269 19.2163
JHOM-1 CTRP2; CTRP1 2.4949 4.5244 2.402 18.3684
TOV-21G CTRP2 3.0883 5.1493 2.9108 14.7235
COV318 CTRP1 3.2407 4.504 3.2044 28.3854
FU-OV-1 CTRP2 3.7425 5.4215 3.546 10.4506
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 1.7651 4.482 1.6212 23.3967
Aska-SS CTRP2 2.1702 3.5221 2.1615 20.24
BT-16 CTRP2 -1.5037 1.8879 -1.5431 44.7273
TE 617.T CTRP2 -0.6581 1.9153 -0.6737 39.0679
Rh41 CTRP2 -0.4961 1.9328 -0.5088 37.9824
TTC-709 CTRP2 -0.4687 2.6903 -0.523 37.9273
GCT CTRP2 0.1211 2.2418 0.1112 33.87
Rh18 CTRP2 0.1621 2.6406 0.1367 33.6483
KYM-1 CTRP2 0.5204 2.5679 0.5083 31.2223
Hs 729.T CTRP2 0.5361 1.7901 0.5358 31.0784
TE 441.T CTRP2 0.5791 2.7163 0.5625 30.8468
Tm87-16 CTRP2 0.7138 3.2396 0.6687 30.0464
RD CTRP2 0.7258 2.2066 0.7241 29.8217
A-204 CTRP2 0.7602 3.5363 0.6877 29.8298
G-401 CTRP2; CTRP1 0.7639 1.9669 0.7636 29.5637
SK-UT-1 CTRP2 0.873 2.9972 0.8515 28.9089
BT-12 CTRP2 0.9381 2.1864 0.9375 28.4062
SW982 CTRP2 0.9937 2.938 0.9788 28.0842
HT-1080 CTRP2; CTRP1 1.0687 2.3823 1.0676 27.5393
RKN CTRP2; CTRP1 1.4628 2.1952 1.4627 24.9153
G-402 CTRP2 1.6088 3.6297 1.5728 24.0651
SK-LMS-1 CTRP2 2.3237 4.2624 2.2591 19.4087
MES-SA CTRP2 7.0022 8.1418 4.8418 0.1071
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.0944 3.9166 2.0565 20.8424
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 -1.3612 2.5665 -1.4495 43.8878
NCI-H28 CTRP2; CTRP1 -0.4814 2.3155 -0.5102 37.9349
NCI-H2052 CTRP2; CTRP1 0.8884 4.4008 0.6873 29.4114
ACC-MESO-1 CTRP2 0.8933 3.741 0.8037 29.003
MPP 89 CTRP2 1.1357 2.8329 1.1278 27.1165
NCI-H2452 CTRP2 1.7285 4.3683 1.6027 25.3716
IST-Mes1 CTRP2 1.9836 4.4635 1.861 21.8703
JL-1 CTRP2 2.5376 3.9142 2.5203 17.8256
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 0.0066 2.8556 -0.0394 34.7486
NCI-H660 CTRP2 0.6751 3.0951 0.6398 30.271
VCaP CTRP2 1.291 3.0644 1.2785 26.0993
PaCa-3 CTRP2; CTRP1 1.5199 2.4141 1.5198 24.5354
LNCaP clone FGC CTRP2 1.7371 3.7923 1.6925 23.241
DU145 CTRP2 1.9388 4.068 1.8747 21.9661
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -0.9492 0.6347 -0.9495 40.9557
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 -4.039 -0.4073 -4.0512 61.2162
GSS CTRP2 -3.2296 -2.0649 -3.2296 56.1193
SNU-719 CTRP2 -2.2606 3.6483 -2.5758 49.7126
SNU-620 CTRP2 -2.0365 -0.0606 -2.0371 48.1863
NUGC-3 CTRP2 -2.0089 1.2295 -2.0308 48.0261
23132/87 CTRP2 -1.543 1.4209 -1.561 44.9442
HGC-27 CTRP2 -1.3771 1.9651 -1.4167 43.8936
KE-39 CTRP2 -1.3706 4.0447 -1.6904 44.3332
AGS CTRP2; CTRP1 -1.1814 0.0434 -1.1815 42.4991
SNU-5 CTRP2 -0.8924 1.5549 -0.9016 40.6051
NUGC-4 CTRP2; CTRP1 -0.7861 2.8899 -0.8766 40.1252
ECC12 CTRP2 -0.7647 2.4428 -0.8126 39.8689
SNU-601 CTRP2 -0.7615 3.3921 -0.9157 40.126
SNU-668 CTRP2 -0.3697 2.2953 -0.3938 37.1782
SNU-216 CTRP2 -0.2909 2.3967 -0.3178 36.6635
NCI-N87 CTRP2 -0.1958 2.7542 -0.2429 36.0957
Fu97 CTRP2; CTRP1 0.0058 2.4486 -0.0146 34.6709
ECC10 CTRP2 0.0956 2.1679 0.0873 34.0342
KATO III CTRP2 0.2249 8.1569 -1.2455 37.0923
SNU-1 CTRP2 0.3146 1.5894 0.3143 32.5515
IM95 CTRP2 0.6503 2.6751 0.6373 30.3616
MKN74 CTRP2; CTRP1 0.9589 3.537 0.8978 28.471
HuG1-N CTRP2 0.9686 2.2282 0.9679 28.2035
Hs 746.T CTRP2 1.1579 2.8589 1.1497 26.9701
SH-10-TC CTRP2; CTRP1 1.3325 2.8362 1.3277 25.7974
GSU CTRP2 1.4437 1.9676 1.4437 25.0418
MKN1 CTRP2 1.5363 2.3998 1.5362 24.4264
OCUM-1 CTRP2 1.7333 4.8781 1.5009 49.7416
LMSU CTRP2 1.8519 3.8757 1.805 22.4856
MKN7 CTRP1 2.1514 3.5674 2.1403 43.7436
MKN45 CTRP2 4.1387 5.4882 3.9544 7.7792
SNG-M CTRP2; CTRP1 0.9204 2.8817 0.9059 28.5702
SNU-685 CTRP2 1.398 2.1836 1.3979 25.3462
SNU-1077 CTRP2 1.8434 4.5779 1.6872 22.9189
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT CTRP2 -1.5989 1.2054 -1.6112 45.3028
8305C CTRP2 -1.2084 1.5336 -1.2229 42.7185
CGTH-W-1 CTRP2 -0.8316 3.3854 -0.9898 40.5926
CAL-62 CTRP2 -0.5668 1.9415 -0.5812 38.4575
B-CPAP CTRP2 0.0477 3.2716 -0.0368 34.5987
FTC-238 CTRP2 0.1149 2.3677 0.1007 33.9254
SW579 CTRP2 0.2524 2.4706 0.2376 33.0132
8505C CTRP2 0.2736 2.5635 0.2555 32.8834
ML-1 [Human leukemia] CTRP2 0.338 4.1437 0.1416 35.5199
BHT-101 CTRP2 0.6043 3.1372 0.5627 30.7626
TT2609-C02 CTRP2 2.1961 4.4423 2.0941 20.3861
FTC-133 CTRP2 3.6315 5.2167 3.4853 11.0039
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 -2.5973 -0.3196 -2.5984 51.9119
SNU-1214 CTRP2 -1.9087 1.2504 -1.9289 47.364
CAL-33 CTRP2 -0.9394 1.7746 -0.9563 40.9395
BHY CTRP2 -0.4917 2.564 -0.5371 38.0533
SCC-25 CTRP2 -0.1501 2.2885 -0.1677 35.6985
CAL-27 CTRP2 0.0716 1.5647 0.0709 34.1688
Detroit 562 CTRP2 0.1087 2.1891 0.1001 33.9482
PE/CA-PJ49 CTRP2 0.1263 1.1898 0.1262 33.803
PE/CA-PJ34 (clone C12) CTRP2 0.3573 3.8344 0.2163 32.7288
SNU-1066 CTRP2 0.4432 3.6864 0.3307 32.0674
YD-8 CTRP2 0.4993 2.6229 0.4846 31.3713
BICR 18 CTRP2 0.5019 2.7121 0.4834 31.3662
BICR 22 CTRP2 0.5582 2.8433 0.5347 31.0086
SNU-1076 CTRP2 0.6684 2.4115 0.6632 30.2149
BICR 56 CTRP2 0.8439 4.2459 0.6695 29.6162
HSC-3 CTRP2 0.8946 2.2222 0.8936 28.6968
PE/CA-PJ15 CTRP2 1.0547 3.891 0.9553 27.9641
HSC-2 CTRP2; CTRP1 1.1283 2.8793 1.1189 27.1706
SCC-4 CTRP2 1.1389 4.0082 1.0281 27.4432
SNU-899 CTRP2 1.394 2.6627 1.3924 25.3779
HSC-4 CTRP2 1.3949 3.4057 1.367 25.4603
BICR 16 CTRP2 1.4683 3.8317 1.4039 25.0956
SNU-46 CTRP2 1.5012 5.3073 1.1354 25.9236
FaDu CTRP2 1.5762 3.0034 1.5714 24.1771
SCC-9 CTRP2; CTRP1 1.8185 3.1987 1.8128 22.5687
SNU-1041 CTRP2 1.857 6.6091 1.0918 24.9972
BICR 6 CTRP2 2.0589 4.5476 1.9266 21.4033
PE/CA-PJ41 (clone D2) CTRP2 2.5486 4.1577 2.5109 17.8212
BICR 31 CTRP2 3.4151 4.8272 3.3408 12.1867
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 -3.1943 -1.807 -3.1943 55.8843
253J-BV CTRP2 -3.1801 1.4622 -3.2583 55.4611
253J CTRP2 -1.6762 0.7464 -1.6805 45.799
639V CTRP2 -1.1759 1.103 -1.1803 42.475
5637 CTRP2; CTRP1 -1.0653 2.1128 -1.1026 41.8288
BFTC-905 CTRP2 -0.7506 2.2816 -0.7869 39.7428
VM-CUB-1 CTRP2 -0.721 1.9144 -0.738 39.4899
RT-112 CTRP2 -0.2485 2.0875 -0.261 36.3359
RT-4 CTRP2; CTRP1 -0.1882 2.2376 -0.2047 35.9479
647V CTRP2 -0.0051 1.7266 -0.0072 34.6836
HT-1376 CTRP2; CTRP1 0.0198 2.3759 0.003 39.9633
U-BLC1 CTRP2 0.28 2.6502 0.2579 32.8538
CAL-29 CTRP2 0.4791 2.5174 0.4679 31.4939
TCCSUP CTRP2 0.6651 2.5134 0.6576 30.2447
UM-UC-3 CTRP2; CTRP1 0.745 3.7351 0.6463 30.0185
SW1710 CTRP2 0.9405 3.0801 0.9165 28.4684
SCaBER CTRP2 1.6049 3.8284 1.5491 24.1581
J82 CTRP2 1.6499 3.7035 1.6093 23.8074
HT-1197 CTRP2 1.693 2.8706 1.6915 23.389
KMBC-2 CTRP2; CTRP1 1.8852 3.7801 1.8494 22.2262
BC-3C CTRP2 2.0298 4.347 1.9311 21.4801
T24 CTRP2 2.2028 3.9192 2.1702 20.1035
UM-UC-1 CTRP2 3.1957 5.5987 2.8943 14.4623
KU-19-19 CTRP2 3.3704 4.9401 3.269 12.5787
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 0.3763 2.057 0.3736 32.1491

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