Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4Y95F)

Drug Name
Cephaloridine Drug Info
Synonyms
cephaloridine; cefaloridine; Cefaloridin; Cephaloridin; Cephaloridinum; Cepaloridin; Cefalorizin; Cephalomycine; Cefaloridinum; Cepalorin; Cefaloridina; Loridine; Ceflorin; 50-59-9; Kefloridin; Glaxoridin; Ceporin; Vioviantine; Intrasporin; Sefacin; Keflordin; Deflorin; Cilifor; Ceporan; Sasperin; Faredina; Ceporine; Keflodin; Verolgin; Lloncefal; Kefspor; Ampligram; Betaine cephaloridine; CHEBI:3537; UNII-LVZ1VC61HB; Cefaloridinum [INN-Latin]; Cefaloridina [INN-Spanish]; N-(7-(2'-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate; SCH
Indication
Disease Entry ICD 11 Status REF
Gram-positive bacterial infection 1B74-1G40 Withdrawn from market [1]
Cross-matching ID
PubChem CID
5773
ChEBI ID
CHEBI:3537
CAS Number
CAS 50-59-9
TTD Drug ID
DM4Y95F
VARIDT Drug ID
DR00612
INTEDE Drug ID
DR0285

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Transported By Peptide transporter 1 (SLC15A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [8]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [9]
Ampicillin DMHWE7P Acute epiglottitis Approved [10]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [11]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [12]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [13]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [2]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [9]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [11]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Organic anion transporter 3 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [15]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [16]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [17]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [18]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [19]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [20]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [21]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [22]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [23]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [36]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [17]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [37]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [37]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [3]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [3]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [38]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [39]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [24]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [25]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [28]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [29]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [25]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [30]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Beta-lactamase (blaB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [32]
Ampicillin DMHWE7P Acute epiglottitis Approved [6]
Piperacillin DMTBKF3 Acute gonococcal cervicitis Approved [6]
Cefalotin DMVYSLE Bacteremia 1A73 Approved [6]
Benzylpenicillin DMS9503 Actinomycosis Phase 3 [6]
Cefotaxime DMEB837 Bacteremia 1A73 Approved [33]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Glutathione peroxidase 1 (GPX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [41]
Amlexanox DM0DQM5 Respiratory tract inflammation CA07 Approved [42]
Selenium DM25CGV N. A. N. A. Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 22 member 6 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [50]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [50]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [50]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [52]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [50]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [53]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [50]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [2]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [4]
Beta-lactamase (blaB) DEKGVS4 PENA_BURM1 Substrate [5]
Beta-lactamase (blaB) DET9I1W BLAC_BACUN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Drug Response [7]
Organic anion transporter 3 (SLC22A8) OT8BY933 S22A8_HUMAN Regulation of Drug Effects [3]
Solute carrier family 22 member 6 (SLC22A6) OTKRCBVM S22A6_HUMAN Regulation of Drug Effects [3]

References

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22 The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin. J Pharmacol Exp Ther. 2007 Sep;322(3):1221-7.
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34 Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress. Toxicology. 2023 Jan 1;483:153387. doi: 10.1016/j.tox.2022.153387. Epub 2022 Dec 1.
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