Details of the Drug

General Information of Drug (ID: DM6CHNJ)

Drug Name
Camptothecin
Synonyms
camptothecin; Camptothecine; 7689-03-4; (S)-(+)-Camptothecin; Campathecin; d-Camptothecin; (+)-Camptothecine; (+)-Camptothecin; 20(S)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; (S)-Camptothecin; Camptothecine (8CI); 20(S)-Camptothecin; Camptothecine (S,+); CHEMBL65; UNII-XT3Z54Z28A; MLS000766223; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; XT3Z54Z28A; CHEBI:27656; VSJKWCGYPAHWDS-FQEVSTJZSA-N; Camptothecin, Camptotheca acuminata; NSC-94600; Camptothecin derivat
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Affected Organisms
Humans and other mammals
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 348.4
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H16N2O4
IUPAC Name
(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Canonical SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
InChI
InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
InChIKey
VSJKWCGYPAHWDS-FQEVSTJZSA-N
Cross-matching ID
PubChem CID
24360
ChEBI ID
CHEBI:27656
CAS Number
7689-03-4
UNII
XT3Z54Z28A
DrugBank ID
DB04690
TTD ID
D09YDM
VARIDT ID
DR01383
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase I (TOP1) TTGTQHC TOP1_HUMAN Modulator [1]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [2]
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [3]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
A-kinase anchor protein 13 (AKAP13) OTOZAR14 AKP13_HUMAN Drug Response [5]
A-kinase anchor protein 8 (AKAP8) OTK3EQAI AKAP8_HUMAN Gene/Protein Processing [6]
Activin receptor type-1B (ACVR1B) OT778HIQ ACV1B_HUMAN Post-Translational Modifications [7]
Adenomatous polyposis coli protein (APC) OTKV0TIK APC_HUMAN Post-Translational Modifications [7]
Agouti-related protein (AGRP) OT7XRHWU AGRP_HUMAN Drug Response [5]
Agrin (AGRN) OTWJENAZ AGRIN_HUMAN Gene/Protein Processing [8]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [9]
AMSH-like protease (STAMBPL1) OTI4CYTF STALP_HUMAN Post-Translational Modifications [7]
Annexin A4 (ANXA4) OTUCRYXL ANXA4_HUMAN Gene/Protein Processing [8]
Antigen peptide transporter 1 (TAP1) OTJL27PW TAP1_HUMAN Gene/Protein Processing [8]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
DNA topoisomerase I (TOP1) DTT TOP1 6.65E-01 0.2 0.39
Breast cancer resistance protein (ABCG2) DTP BCRP 3.87E-47 -1.28E+00 -1.63E+00
Multidrug resistance-associated protein 2 (ABCC2) DTP MRP2 1.02E-08 -5.12E-02 -2.22E-01
Multidrug resistance-associated protein 4 (ABCC4) DTP MRP4 1.26E-03 -4.35E-01 -5.28E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 -3.9315 -0.3996 -5.3177 14.48
EW-22 GDSC2 -7.7756 -5.8074 -7.7879 44.736
ES8 GDSC2 -7.4746 -6.0462 -7.4768 41.6828
SK-ES-1 GDSC2 -7.4646 -6.1408 -7.4659 41.5783
EW-3 GDSC2 -7.415 -4.4709 -7.5357 41.5264
A-673 GDSC2 -7.3906 -4.7884 -7.4645 41.1246
ES7 GDSC2 -7.3498 -5.4902 -7.3642 40.4848
CADO-ES1 GDSC2 -7.3016 -5.8132 -7.3054 39.9541
EW-12 GDSC2 -7.1094 -5.7565 -7.112 38.0202
SK-PN-DW GDSC2 -6.9997 -5.0947 -7.0242 37.0245
TC-71 GDSC2 -6.868 -5.2592 -6.8795 35.6417
ES1 GDSC2 -6.7795 -5.2881 -6.7877 34.7379
EW-1 GDSC2 -6.5877 -4.3034 -6.6739 33.1969
HuO9 GDSC2 -6.5084 -3.9922 -6.642 32.6357
MHH-ES-1 GDSC2 -6.3652 -3.9237 -6.5003 31.2157
EW-11 GDSC2 -6.1046 -2.7973 -6.5166 30.0051
EW-16 GDSC2 -6.0615 -3.6559 -6.2276 28.3418
EW-7 GDSC2 -6.0236 -3.2176 -6.2995 28.5271
ES4 GDSC2 -5.9893 -2.9442 -6.3441 28.5896
EW-13 GDSC2 -5.8047 -2.9119 -6.1536 26.7364
EW-24 GDSC2 -5.229 -1.8257 -5.9413 23.0335
MG-63 GDSC2 -5.1902 -1.9655 -5.8428 22.3245
NY GDSC2 -4.9474 -2.1288 -5.5206 19.487
ES5 GDSC2 -4.5096 1.975 -7.0154 25.6075
SaOS-2 GDSC2 -4.4635 -1.2832 -5.3992 16.8643
HOS GDSC2 -4.1803 -1.1075 -5.2062 14.6643
CAL-72 GDSC2 -4.0546 -0.0757 -5.5898 16.5307
SJSA-1 GDSC2 -3.6391 -0.4954 -5.0075 11.6146
CAL-78 GDSC2 -3.2957 1.7158 -5.819 15.4489
H-EMC-SS GDSC2 -3.2545 1.5359 -5.6949 14.6114
HuO-3N1 GDSC2 -3.1577 0.6083 -5.1519 11.0708
EW-18 GDSC2 -3.1495 2.7465 -6.2137 17.2051
ES6 GDSC2 -1.7369 3.8284 -5.6779 10.6254
U-CH2 GDSC2 -1.2425 4.3689 -5.6031 9.1698
CHSA8926 GDSC2 -1.1613 4.1126 -5.4298 8.0624
CHSA0011 GDSC2 -0.9521 3.5392 -5.0366 5.5476
CHSA0108 GDSC2 -0.903 2.9154 -4.7301 3.858
G-292 clone A141B1 GDSC2 0.0964 4.2922 -4.7986 2.9412
U2OS GDSC2 0.5157 3.1475 -4.1762 0.4782
NOS-1 [Human HNSCC] GDSC2 0.5841 3.669 -4.3379 0.8455
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 165 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 -7.1161 -5.9599 -7.1169 38.0788
CML-T1 GDSC2 -8.4965 -7.2597 -8.4966 51.9263
JVM-3 GDSC2 -8.0724 -6.1797 -8.0793 47.6859
DoHH2 GDSC2 -8.0327 -6.7462 -8.033 47.2737
OCI-Ly19 GDSC2 -7.9913 -6.1675 -7.9973 46.8736
MOLT-16 GDSC2 -7.7732 -6.6804 -7.7733 44.6697
SUP-M2 GDSC2 -7.7269 -6.4038 -7.7277 44.2082
RPMI-8402 GDSC2 -7.7015 -6.4154 -7.7022 43.9526
SR GDSC2 -7.6916 -6.1949 -7.6938 43.8594
A3/Kawakami GDSC2 -7.6914 -6.4849 -7.6918 43.8502
DEL GDSC2 -7.673 -6.3089 -7.6741 43.6679
IM-9 GDSC2 -7.6438 -6.2659 -7.6451 43.3759
BONNA-12 GDSC2 -7.4709 -4.5714 -7.58 42.0335
NB4 GDSC2 -7.4435 -5.67 -7.4532 41.4035
P32/ISH GDSC2 -7.3922 -6.5139 -7.3922 40.8453
Karpas-231 GDSC2 -7.379 -6.3287 -7.3792 40.7143
MV4-11 GDSC2 -7.3715 -6.0829 -7.3727 40.6437
VL51 GDSC2 -7.3669 -5.4246 -7.385 40.6721
SU-DHL-5 GDSC2 -7.3581 -6.5073 -7.3581 40.5035
SCC-3 GDSC2 -7.3465 -6.2621 -7.3468 40.3888
SU-DHL-16 GDSC2 -7.2913 -4.1897 -7.4515 40.4586
CESS GDSC2 -7.2899 -5.9423 -7.2918 39.8281
KOPN-8 GDSC2 -7.2637 -5.846 -7.2665 39.5697
L-540 GDSC2 -7.2386 -5.515 -7.2492 39.3541
RPMI-6666 GDSC2 -7.2337 -4.8034 -7.2963 39.5274
NALM-6 GDSC2 -7.2181 -6.2747 -7.2182 39.0989
MOLT-4 GDSC2 -7.2024 -5.8724 -7.2044 38.9508
SUP-B15 GDSC2 -7.1889 -6.0728 -7.1894 38.8081
Namalwa GDSC2 -7.181 -6.0552 -7.1815 38.7286
JVM-2 GDSC2 -7.18 -4.7662 -7.2436 38.9976
HAL-01 GDSC2 -7.1681 -5.911 -7.1695 38.6038
BALL-1 GDSC2 -7.1654 -6.3176 -7.1654 38.5697
WIL2 NS GDSC2 -7.1405 -5.8082 -7.1428 38.3311
SUP-T1 GDSC2 -7.1261 -3.7411 -7.367 39.15
NKM-1 GDSC2 -7.1181 -5.1191 -7.1457 38.224
697 GDSC2 -7.1043 -6.0815 -7.1046 37.9578
HC-1 GDSC2 -7.0984 -5.8767 -7.0996 37.9031
MHH-CALL-2 GDSC2 -7.0959 -5.1106 -7.1232 38.001
MOLM-13 GDSC2 -7.0527 -5.4428 -7.0617 37.4823
OCI-AML-2 GDSC2 -7.0414 -6.1288 -7.0415 37.3259
KE-37 GDSC2 -7.0403 -5.7112 -7.0428 37.3266
BV-173 GDSC2 -7.0221 -5.3599 -7.0334 37.1865
QIMR-WIL GDSC2 -7.0015 -4.6522 -7.0679 37.2332
LC4-1 GDSC2 -6.995 -5.4287 -7.0032 36.8997
ALL-PO GDSC2 -6.9794 -4.9936 -7.0104 36.8514
WSU-NHL GDSC2 -6.9653 -4.7978 -7.0132 36.7884
P12-Ichikawa GDSC2 -6.9532 -5.924 -6.9536 36.4421
CCRF-CEM GDSC2 -6.9288 -5.6694 -6.931 36.2063
JSC-1 GDSC2 -6.9067 -5.6219 -6.9092 35.9862
Hs 445 GDSC2 -6.9048 -5.1929 -6.9204 36.0311
VAL GDSC2 -6.8899 -4.4907 -6.97 36.183
DB GDSC2 -6.8822 -4.5921 -6.9486 36.0438
SUP-B8 GDSC2 -6.8291 -5.0648 -6.8492 35.2938
RCH-ACV GDSC2 -6.8117 -5.0318 -6.8332 35.1263
Farage GDSC2 -6.8033 -4.6808 -6.8545 35.1843
RS4;11 GDSC2 -6.783 -5.3 -6.791 34.7719
MOLT-13 GDSC2 -6.7787 -5.2569 -6.7881 34.7358
YT GDSC2 -6.7775 -4.6682 -6.8286 34.9258
NU-DUL-1 GDSC2 -6.7722 -5.4858 -6.7754 34.6398
RPMI-8866 GDSC2 -6.7492 -4.5336 -6.8145 34.7104
H9 GDSC2 -6.7161 -5.3463 -6.7214 34.0873
Granta-519 GDSC2 -6.7088 -4.102 -6.8381 34.6072
KY821 GDSC2 -6.7077 -5.3801 -6.7121 33.9989
Karpas-1106P GDSC2 -6.6993 -4.4301 -6.775 34.2616
SUP-HD1 GDSC2 -6.678 -2.3417 -7.2923 36.3162
ALL-SIL GDSC2 -6.6629 -4.9908 -6.6816 33.6203
PF-382 GDSC2 -6.6612 -4.6744 -6.7052 33.7276
EB2 GDSC2 -6.6569 -4.8473 -6.6851 33.6071
SU-DHL-8 GDSC2 -6.6476 -4.9768 -6.6666 33.4681
ARH-77 GDSC2 -6.6236 -5.1714 -6.6325 33.1768
Raji GDSC2 -6.6227 -4.7064 -6.6615 33.3161
NK-92MI GDSC2 -6.604 -5.1596 -6.6129 32.9805
OCI-M1 GDSC2 -6.5723 -5.2239 -6.5784 32.6487
OCI-Ly7 GDSC2 -6.5643 -5.3461 -6.5675 32.5532
HL-60 GDSC2 -6.5423 -5.1168 -6.5513 32.3617
MC116 GDSC2 -6.5348 -4.7821 -6.5627 32.381
BL-41 GDSC2 -6.5301 -4.9014 -6.5494 32.2914
DND-41 GDSC2 -6.497 -4.6105 -6.5385 32.0694
CTB-1 GDSC2 -6.4827 -4.1868 -6.5795 32.2002
ML-2 GDSC2 -6.4137 -5.0177 -6.4234 31.0747
GDM-1 GDSC2 -6.4121 -3.9707 -6.5419 31.6577
MHH-CALL-4 GDSC2 -6.3776 -2.4213 -6.9397 33.3183
CTV-1 GDSC2 -6.3695 -4.7754 -6.3909 30.6906
JURL-MK1 GDSC2 -6.3662 -4.9547 -6.3774 30.6057
Jurkat GDSC2 -6.3418 -4.8453 -6.3578 30.3856
OCI-AML-5 GDSC2 -6.305 -5.0569 -6.3109 29.9648
SU-DHL-1 GDSC2 -6.2956 -5.2015 -6.2981 29.8534
WSU-DLCL2 GDSC2 -6.2781 -3.9565 -6.3997 30.2791
SKM-1 GDSC2 -6.257 -4.9071 -6.2673 29.5053
ATN-1 GDSC2 -6.2486 -4.9371 -6.2574 29.4135
JeKo-1 GDSC2 -6.1675 -4.1534 -6.2462 28.9548
EoL-1 GDSC2 -6.106 -5.0285 -6.1093 27.9552
EM-2 GDSC2 -6.0958 -4.7744 -6.1077 27.896
Reh GDSC2 -6.0427 -4.5362 -6.0681 27.4318
MY-M12 GDSC2 -6.0419 -4.4731 -6.0729 27.4522
P30/OHK GDSC2 -6.0082 -5.0021 -6.0108 26.9698
TALL-1 [Human adult T-ALL] GDSC2 -5.9658 -2.8176 -6.3592 28.5538
LAMA-84 GDSC2 -5.9506 -3.9189 -6.0526 26.9016
A4/Fukuda GDSC2 -5.8896 -3.3386 -6.1195 26.9577
SU-DHL-4 GDSC2 -5.8705 -3.9789 -5.9554 26.01
GR-ST GDSC2 -5.8545 -1.7299 -6.6392 29.4046
CRO-AP2 GDSC2 -5.7858 -3.4893 -5.967 25.6657
Mono-Mac-6 GDSC2 -5.7645 -4.1502 -5.8155 24.7716
HEL GDSC2 -5.6759 -4.7398 -5.6793 23.6397
MM1.S GDSC2 -5.5803 -4.3086 -5.6033 22.7796
RL GDSC2 -5.5411 -3.4453 -5.7113 23.1587
NOMO-1 GDSC2 -5.4986 -4.2189 -5.5257 21.9803
NCI-H929 GDSC2 -5.4856 -2.6991 -5.8785 23.8092
Daudi GDSC2 -5.4677 -2.9919 -5.7614 23.0914
SU-DHL-6 GDSC2 -5.4414 -3.2401 -5.6578 22.4093
OCI-AML-3 GDSC2 -5.4214 -3.1096 -5.6744 22.4079
BC-1 GDSC2 -5.3851 -3.0829 -5.643 22.0722
P31/FUJ GDSC2 -5.337 -3.5643 -5.4599 20.8609
Jiyoye GDSC2 -5.2765 -3.0007 -5.5507 21.0764
Ku812 GDSC2 -5.2588 -2.9889 -5.5352 20.9115
KG-1 GDSC2 -5.2141 -2.7452 -5.5689 20.8996
L-428 GDSC2 -5.1551 -2.8525 -5.4679 20.0776
RC-K8 GDSC2 -5.1452 -1.9614 -5.7972 21.8801
RPMI-8226 GDSC2 -5.1294 -1.8463 -5.8285 21.9885
PL-21 GDSC2 -5.0712 -2.8197 -5.3883 19.2645
AMO1 GDSC2 -5.0417 -2.5821 -5.4423 19.44
MN-60 GDSC2 -5.0294 -1.3509 -5.9386 22.1876
Karpas-422 GDSC2 -5.0057 -1.2389 -5.9641 22.2325
MLMA GDSC2 -5.0037 -1.2209 -5.9701 22.2575
Karpas-299 GDSC2 -4.9999 -2.0533 -5.6068 20.1977
TUR GDSC2 -4.9524 -3.3195 -5.1019 17.1497
MOLM-16 GDSC2 -4.936 -2.0133 -5.5564 19.6452
TK [Human B-cell lymphoma] GDSC2 -4.9162 -2.9905 -5.1623 17.3193
SU-DHL-10 GDSC2 -4.8461 -1.7412 -5.5794 19.4105
MOLP-8 GDSC2 -4.8319 -1.8797 -5.5048 18.9221
KM-H2 GDSC2 -4.8162 -1.9982 -5.438 18.4721
MEG-01 GDSC2 -4.7616 -1.2715 -5.7023 19.7816
ST486 GDSC2 -4.7523 -0.4138 -6.0903 21.9222
Kasumi-1 GDSC2 -4.6653 1.9914 -7.1671 26.8385
U-698-M GDSC2 -4.5941 -1.0953 -5.6158 18.6333
ROS-50 GDSC2 -4.5574 -1.513 -5.3871 17.1498
BC-3 GDSC2 -4.5205 -2.8383 -4.7879 13.4858
BE-13 GDSC2 -4.2981 -0.6099 -5.5579 17.1969
THP-1 GDSC2 -4.2413 2.6653 -7.1125 25.0869
KCL-22 GDSC2 -4.2233 -1.1568 -5.2241 14.9271
KMS-12-BM GDSC2 -4.1566 -2.2343 -4.6564 11.2369
KMOE-2 GDSC2 -4.1219 -1.7695 -4.8355 12.1919
GA-10 GDSC2 -3.9545 -0.2496 -5.4126 15.1323
SK-MM-2 GDSC2 -3.9408 -0.2398 -5.4049 15.0391
SIG-M5 GDSC2 -3.8689 -0.06 -5.4285 14.942
EJM GDSC2 -3.8037 -1.4786 -4.6705 10.0491
HDLM-2 GDSC2 -3.7039 0.0787 -5.3502 13.9315
L-1236 GDSC2 -3.6784 -0.6504 -4.9653 11.4769
DG-75 GDSC2 -3.6752 -0.8932 -4.842 10.6968
OPM-2 GDSC2 -3.3734 0.084 -5.0679 11.1762
Ramos.2G6.4C10 GDSC2 -3.3142 -1.8454 -4.0538 4.6112
HT GDSC2 -3.2771 2.3116 -6.1014 16.9741
K-562 GDSC2 -3.185 0.1328 -4.9366 9.813
Loucy GDSC2 -3.1279 0.2285 -4.9382 9.6632
JJN-3 GDSC2 -3.025 0.397 -4.9401 9.3926
CA46 GDSC2 -2.9357 1.4971 -5.4176 12.0681
MHH-PREB-1 GDSC2 -2.7522 2.0227 -5.5356 12.274
ME1 GDSC2 -2.7085 2.4026 -5.6905 13.0592
Karpas-45 GDSC2 -2.105 2.4002 -5.2432 8.9609
L-363 GDSC2 -1.933 2.6736 -5.256 8.6547
KMS-11 GDSC2 -1.0443 4.325 -5.4549 7.9782
U266B1 GDSC2 -0.2735 4.4156 -5.0427 4.5532
LP-1 GDSC2 0.3533 2.5076 -4.013 0.229
HH [Human lymphoma] GDSC2 0.3859 2.6968 -4.0663 0.3062
Karpas-620 GDSC2 0.5853 2.3756 -3.8901 0.0673
⏷ Show the Full List of 165 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC2 -5.2402 -1.8827 -5.9295 23.0163
KYSE-220 GDSC2 -5.0417 -1.6126 -5.8369 21.6716
OACM5.1 C GDSC2 -4.1709 -1.0403 -5.2294 14.7715
ESO-51 GDSC2 -3.5488 -0.6406 -4.8561 10.3853
OACP4 C GDSC2 -3.0011 0.7693 -5.1067 10.3585
ESO-26 GDSC2 -2.8149 1.0482 -5.1001 9.8225
FLO-1 GDSC2 -2.3457 3.5332 -5.9738 13.7106
SK-GT-4 GDSC2 -0.4544 4.4238 -5.1467 5.3409
TE-12 GDSC2 -0.4419 4.8424 -5.3271 6.2526
KYSE-50 GDSC2 -0.4049 3.284 -4.6272 2.7231
KYAE-1 GDSC2 0.6121 2.4598 -3.9087 0.0781
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 -1.4087 5.2469 -6.1357 12.3652
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC-IXC GDSC2 -8.2092 -6.9601 -8.2094 49.0449
MHH-NB-11 GDSC2 -7.5549 -5.9034 -7.5602 42.5011
NB69 GDSC2 -7.2628 -5.0349 -7.3036 39.7272
IMR-5 GDSC2 -6.8647 -5.2657 -6.8758 35.6069
SJNB-10 GDSC2 -6.7186 -3.9972 -6.8687 34.8003
SiMa GDSC2 -6.507 -4.1916 -6.6049 32.4482
SJNB-14 GDSC2 -6.4564 -3.6901 -6.6497 32.4062
NH-12 GDSC2 -6.3362 -2.9256 -6.7277 32.1605
CHP-126 GDSC2 -6.1611 -2.7866 -6.5815 30.5967
Kelly GDSC2 -6.0401 -3.4202 -6.2621 28.4156
SK-N-SH GDSC2 -5.9193 -1.6641 -6.7341 30.1523
GOTO GDSC2 -5.9029 -1.2966 -6.867 30.677
SJNB-17 GDSC2 -5.756 -3.8379 -5.8573 24.9478
CHP-134 GDSC2 -5.6773 -3.2124 -5.9231 24.9246
KP-N-RT-BM-1 GDSC2 -5.5551 -1.0038 -6.6303 28.0055
SJNB-13 GDSC2 -5.3503 -0.7885 -6.5156 26.5609
CHP-212 GDSC2 -5.2936 0.1315 -6.8783 28.0376
KP-N-YS GDSC2 -5.1337 -2.1687 -5.7008 21.2913
SJNB-5 GDSC2 -5.1331 -1.9299 -5.7975 21.8309
SK-N-DZ GDSC2 -4.9761 -0.1276 -6.4442 24.6626
NB1 GDSC2 -4.8077 -2.2547 -5.322 17.7655
NB(TU)1 GDSC2 -4.4673 -0.7589 -5.6495 18.3527
KP-N-YN GDSC2 -4.2057 2.1596 -6.8301 23.684
SK-N-BE(2)-M17 GDSC2 -4.1928 -1.0343 -5.2533 14.995
SJNB-7 GDSC2 -3.7271 0.2762 -5.4689 14.723
TGW GDSC2 -3.5605 1.6291 -5.999 17.2737
SJNB-12 GDSC2 -2.6968 3.72 -6.3364 16.5746
SK-N-FI GDSC2 -2.684 3.2352 -6.0852 15.2038
SK-N-AS GDSC2 -2.6251 4.3291 -6.5834 17.6355
LA-N-6 GDSC2 -0.9241 4.4076 -5.4181 7.5573
SJNB-6 GDSC2 -0.1263 3.0374 -4.3962 1.4892
GI-ME-N GDSC2 0.2775 8.9094 -6.7613 12.0371
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 -2.2863 3.2086 -5.7694 12.4264
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2 -6.4737 -3.4498 -6.7275 32.7505
DU4475 GDSC2 -5.9341 -3.216 -6.2023 27.5034
CAL-51 GDSC2 -4.8483 -1.001 -5.9126 21.2439
HCC1599 GDSC2 -4.8167 -1.8806 -5.4887 18.7024
AU565 GDSC2 -4.577 -1.9345 -5.2183 16.1716
HCC1806 GDSC2 -4.4088 -0.8116 -5.5677 17.5978
HCC2157 GDSC2 -4.0203 -1.1831 -5.0174 12.9436
MDA-MB-468 GDSC2 -4.0044 0.1815 -5.6705 16.7785
BT-20 GDSC2 -3.8105 -0.4097 -5.2029 13.3305
HCC38 GDSC2 -3.6384 -0.4015 -5.0536 11.8576
MDA-MB-231 GDSC2 -3.4735 1.1674 -5.6941 15.2131
MDA-MB-453 GDSC2 -3.409 -0.6539 -4.7292 9.1301
MDA-MB-175-VII GDSC2 -3.3336 0.6862 -5.3357 12.7048
CAL-120 GDSC2 -3.3132 1.6597 -5.8054 15.3736
HCC1395 GDSC2 -2.9639 2.2934 -5.8371 14.5487
HDQ-P1 GDSC2 -2.9638 0.7066 -5.046 9.8497
MRK-nu-1 GDSC2 -2.917 2.3189 -5.8124 14.2782
MCF-7 GDSC2 -2.831 3.6562 -6.4108 17.2789
UACC-812 GDSC2 -2.7815 2.0814 -5.5875 12.6563
YMB-1-E GDSC2 -2.745 0.9628 -5.0045 9.0567
CAL-85-1 GDSC2 -2.3768 0.9543 -4.7328 6.4967
OCUB-M GDSC2 -2.2817 6.5402 -7.4152 20.4763
JIMT-1 GDSC2 -2.2529 2.3232 -5.3108 9.6674
T-47D GDSC2 -2.229 2.088 -5.179 8.8349
MDA-MB-436 GDSC2 -2.1127 3.8131 -5.9387 12.9005
BT-549 GDSC2 -1.9008 4.0314 -5.8921 12.143
MDA-MB-157 GDSC2 -1.6678 3.2333 -5.3446 8.5699
COLO 824 GDSC2 -0.8852 2.9772 -4.7475 3.9081
EFM-19 GDSC2 -0.7168 3.4479 -4.8615 4.2503
HCC1428 GDSC2 -0.6293 1.9823 -4.2059 1.1734
Evsa-T GDSC2 -0.4816 4.7128 -5.2918 6.1132
Hs 578T GDSC2 -0.4225 5.7012 -5.7071 8.1614
MDA-MB-361 GDSC2 -0.4053 4.9177 -5.3398 6.2395
HCC1569 GDSC2 -0.3961 5.6546 -5.6696 7.9235
HCC1937 GDSC2 -0.3947 5.1519 -5.4394 6.7357
HCC1500 GDSC2 -0.2837 3.7979 -4.7823 3.2905
EFM-192A GDSC2 -0.2768 1.8215 -4.0034 0.3858
HCC1143 GDSC2 -0.2028 2.7309 -4.3104 1.2317
MFM-223 GDSC2 -0.1418 1.7363 -3.9247 0.2046
ZR-75-30 GDSC2 0.0032 2.1147 -4.003 0.2973
HCC1419 GDSC2 0.0269 2.1825 -4.018 0.3178
UACC-893 GDSC2 0.1203 7.6206 -6.26 9.9578
HCC70 GDSC2 0.1407 2.9497 -4.25 0.8244
CAMA-1 GDSC2 0.2253 6.6704 -5.763 7.3718
MDA-MB-415 GDSC2 0.2311 2.5372 -4.0671 0.3496
BT-474 GDSC2 0.3012 1.9895 -3.858 0.0685
HCC2218 GDSC2 0.3354 2.1196 -3.8893 0.0894
BT-483 GDSC2 0.3817 6.5872 -5.6365 6.5183
HCC1954 GDSC2 0.3973 2.8366 -4.1107 0.3827
HCC1187 GDSC2 0.4986 2.4292 -3.9366 0.1129
MDA-MB-330 GDSC2 0.7583 2.9209 -4.0119 0.1546
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC2 -7.1022 -3.5011 -7.3999 39.1231
D283 Med GDSC2 -6.7832 -4.2504 -6.8924 35.2542
AM-38 GDSC2 -6.6222 -3.9478 -6.7741 33.8535
8-MG-BA GDSC2 -6.2186 -3.401 -6.4619 30.2953
Daoy GDSC2 -6.0238 -2.7411 -6.4474 29.2732
MOG-G-UVW GDSC2 -5.9942 -3.1707 -6.2809 28.291
SF295 GDSC2 -5.8382 -2.9516 -6.1774 27.0168
Hs 683 GDSC2 -5.6891 -2.6977 -6.0991 25.9149
SW1783 GDSC2 -5.5792 -2.0666 -6.2138 26.0212
GI-1 GDSC2 -5.5372 -2.6661 -5.9458 24.4056
SF539 GDSC2 -5.3108 -1.9962 -5.9573 23.471
SF126 GDSC2 -5.1664 -1.9153 -5.8385 22.2001
M059J GDSC2 -5.1243 -2.4265 -5.5896 20.6251
U-251MG GDSC2 -5.0985 -1.6243 -5.8906 22.2058
GB-1 GDSC2 -5.0959 -1.3103 -6.0245 22.9336
42-MG-BA GDSC2 -5.0099 -1.2281 -5.9732 22.2998
D-566MG GDSC2 -5.0056 -2.0778 -5.6026 20.1974
U-118MG GDSC2 -4.9582 -1.291 -5.8925 21.6421
D-245MG GDSC2 -4.9363 -0.5662 -6.2006 23.238
A-172 GDSC2 -4.6757 -1.0763 -5.7057 19.4673
SF268 GDSC2 -4.3702 -0.0175 -5.9124 19.5075
D-423MG GDSC2 -4.0877 -1.3691 -4.9921 13.0261
Becker GDSC2 -4.0787 0.5966 -5.9428 18.6537
U-87MG ATCC GDSC2 -3.836 -0.2931 -5.2835 13.9539
YKG-1 GDSC2 -3.7354 0.6204 -5.6475 15.812
SNB-75 GDSC2 -3.4506 -1.1565 -4.5137 7.9272
GaMG GDSC2 -3.4065 0.9869 -5.5472 14.1943
D-263MG GDSC2 -3.3576 1.9134 -5.9694 16.4858
D-392MG GDSC2 -3.3423 3.5955 -6.7976 20.7355
ONS-76 GDSC2 -3.258 0.9794 -5.4196 12.9902
D-336MG GDSC2 -3.0987 0.1044 -4.8528 9.0492
T98G GDSC2 -2.8539 2.5156 -5.8604 14.4214
SK-MG-1 GDSC2 -2.8226 1.6935 -5.4266 11.8166
KNS-42 GDSC2 -2.7748 0.5826 -4.839 8.1117
D-502MG GDSC2 -2.768 4.2989 -6.6811 18.5087
LN-18 GDSC2 -2.3331 4.5664 -6.4754 16.3211
Onda 10 GDSC2 -2.0856 3.5405 -5.7853 12.0273
MOG-G-CCM GDSC2 -1.6744 5.873 -6.6291 15.4547
PFSK-1 GDSC2 -1.6427 4.8587 -6.1114 12.7615
YH-13 GDSC2 -1.5202 4.1925 -5.7043 10.2992
KNS-81-FD GDSC2 -1.2104 5.7935 -6.2625 12.5853
CAS-1 GDSC2 -1.1609 5.8831 -6.2717 12.5258
SW1088 GDSC2 -1.0579 5.7503 -6.1382 11.6283
KS-1 [Human Krukenberg tumour] GDSC2 -0.7589 4.6144 -5.412 7.2301
DBTRG-05MG GDSC2 -0.7238 6.8081 -6.4196 12.3513
Onda 11 GDSC2 -0.6573 2.4753 -4.4161 2.0507
LN-229 GDSC2 -0.5975 5.3355 -5.6458 8.178
NMC-G1 GDSC2 -0.594 7.6946 -6.7561 13.6876
LNZTA3WT4 GDSC2 -0.5704 7.4102 -6.6044 12.9295
DK-MG GDSC2 -0.3576 2.6954 -4.365 1.5594
LN-405 GDSC2 -0.1663 5.2186 -5.3374 5.8766
D-247MG GDSC2 -0.1219 9.0242 -7.075 14.1796
KINGS-1 GDSC2 -0.0414 5.0938 -5.2127 5.0718
KALS-1 GDSC2 0.0639 7.3571 -6.1729 9.6646
D-542MG GDSC2 0.384 2.5256 -4.0084 0.216
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 -1.7035 3.287 -5.3943 8.9565
TGBC1TKB GDSC2 -0.9204 4.3559 -5.3918 7.409
TGBC24TKB GDSC2 -0.388 2.848 -4.4399 1.8875
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 -7.0805 -5.3726 -7.0927 37.7763
MFE-296 GDSC2 -2.7935 1.269 -5.1933 10.3348
MFE-280 GDSC2 -2.127 2.1606 -5.1426 8.4177
MFE-319 GDSC2 -1.9481 3.1793 -5.511 10.158
AN3-CA GDSC2 -0.5654 3.894 -4.9742 4.6218
RL95-2 GDSC2 -0.4379 6.0931 -5.8981 9.1924
KLE GDSC2 -0.1904 4.2819 -4.9403 3.9399
EN GDSC2 0.5136 3.7163 -4.3838 1.0155
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW13 GDSC2 -6.3042 -3.7672 -6.4667 30.7437
LB996-RCC GDSC2 -6.2587 -3.4614 -6.4899 30.6322
ACHN GDSC2 -5.8705 -3.8491 -5.979 26.1327
CAL-54 GDSC2 -5.6376 -1.5446 -6.4861 27.6707
Caki-1 GDSC2 -5.4468 -0.1128 -6.9184 28.8642
KTCTL-13 GDSC2 -5.3969 -1.7819 -6.1355 24.8052
LB2241-RCC GDSC2 -5.3081 -3.346 -5.4829 20.8502
786-O GDSC2 -5.2865 -2.5889 -5.7028 21.9616
KTCTL-140 GDSC2 -5.2365 -1.8319 -5.9465 23.094
KTCTL-21 GDSC2 -4.8667 -2.5752 -5.2576 17.6428
KMRC-20 GDSC2 -4.3961 -0.5624 -5.6744 18.236
UO-31 GDSC2 -4.2832 -0.892 -5.4083 16.2531
HA7-RCC GDSC2 -4.2288 -1.0876 -5.2623 15.1785
BFTC-909 GDSC2 -4.1902 -1.0177 -5.2588 15.0189
LB1047-RCC GDSC2 -3.921 -0.5858 -5.2165 13.8268
KTCTL-195 GDSC2 -3.8094 0.823 -5.8134 17.0169
769-P GDSC2 -3.5904 0.6733 -5.5474 14.7598
SW156 GDSC2 -3.5815 0.2893 -5.3481 13.5326
KTCTL-26A GDSC2 -3.4701 -0.0435 -5.0862 11.5801
KTCTL-1M GDSC2 -3.3234 0.2777 -5.123 11.3703
BB65-RCC GDSC2 -3.2917 0.8967 -5.4061 13.0071
RCC10RGB GDSC2 -3.2173 0.9567 -5.3747 12.6009
A-498 GDSC2 -3.039 2.589 -6.045 15.97
SN12C GDSC2 -2.893 0.6953 -4.9852 9.3198
NCC021 GDSC2 -2.6554 3.2415 -6.0661 15.023
A-704 GDSC2 -2.4939 3.7599 -6.1987 15.3074
KMRC-1 GDSC2 -2.4391 1.7427 -5.1615 9.2541
NCC010 GDSC2 -1.9456 4.3564 -6.0832 13.3186
OS-RC-2 GDSC2 -1.3661 5.7184 -6.3341 13.2876
TK-10 GDSC2 -1.1948 3.7289 -5.2716 7.2554
RXF 393L GDSC2 -0.8631 3.6784 -5.0474 5.4603
VMRC-RCZ GDSC2 -0.495 4.0869 -5.0202 4.7541
VMRC-RCW GDSC2 -0.0744 1.6273 -3.8646 0.1165
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-CO-1 GDSC2 -7.5877 -4.7473 -7.6797 42.9733
SW48 GDSC2 -5.8427 -2.644 -6.2839 27.4951
MDST8 GDSC2 -5.5866 -2.9632 -5.8999 24.2974
RKO GDSC2 -5.5194 -2.7492 -5.8978 23.9822
LoVo GDSC2 -5.2536 -1.2666 -6.2055 24.4823
GP5d GDSC2 -4.8975 -0.0673 -6.3955 24.0268
SW620 GDSC2 -4.759 -0.4638 -6.0734 21.7839
NCI-H508 GDSC2 -4.6952 -0.1654 -6.1522 21.9673
LS180 GDSC2 -4.6325 0.5123 -6.4169 23.1225
CaR-1 GDSC2 -4.4956 -1.9682 -5.1201 15.2726
HCT 116 GDSC2 -4.4671 -0.1081 -5.9605 20.0648
LS513 GDSC2 -4.4266 0.3029 -6.121 20.8021
SNU-175 GDSC2 -4.2576 1.0465 -6.3277 21.3028
HCT 15 GDSC2 -4.2517 -0.5921 -5.5223 16.7625
RCM-1 [Human ESC] GDSC2 -3.8642 -1.7375 -4.6016 9.795
HT-29 GDSC2 -3.8441 -1.8309 -4.5374 9.3283
SNU-C5 GDSC2 -3.6782 0.1644 -5.3702 13.9233
CW-2 GDSC2 -3.6316 0.2135 -5.3539 13.6782
CCK-81 GDSC2 -3.6274 -0.4942 -4.9978 11.4777
SW1463 GDSC2 -3.3861 0.3212 -5.1973 11.9726
CL-11 GDSC2 -3.3592 2.8522 -6.4401 18.9606
SW948 GDSC2 -3.2446 2.6568 -6.2471 17.6101
T84 GDSC2 -3.017 1.1342 -5.3012 11.5513
KM12 GDSC2 -2.9545 1.526 -5.4469 12.2541
DiFi GDSC2 -2.8197 2.5666 -5.8588 14.2733
LS411N GDSC2 -2.8137 1.1282 -5.139 10.0226
SNU-283 GDSC2 -2.6845 0.6746 -4.817 7.7515
SW1417 GDSC2 -2.3843 2.4655 -5.4763 10.9507
LS1034 GDSC2 -2.3278 0.6191 -4.5382 5.2231
SNU-407 GDSC2 -2.2558 4.2267 -6.2488 14.9133
NCI-H747 GDSC2 -2.111 1.9109 -5.0109 7.5767
COLO 320HSR GDSC2 -1.8763 2.1679 -4.9757 6.8777
SW626 GDSC2 -1.7056 2.8861 -5.2042 7.8742
COLO205 GDSC2 -1.4976 3.7507 -5.4778 8.9675
SW837 GDSC2 -1.4929 3.2956 -5.2587 7.7301
HT-55 GDSC2 -1.2428 2.8592 -4.8997 5.2716
SNU-C2B GDSC2 -1.153 3.6018 -5.1866 6.6879
HT115 GDSC2 -1.1255 4.2473 -5.4701 8.1884
C2BBe1 GDSC2 -1.0345 3.3537 -5.001 5.4736
LS123 GDSC2 -0.7675 5.1772 -5.6782 8.6306
SW1116 GDSC2 -0.62 3.7614 -4.946 4.5572
HCC2998 GDSC2 -0.6114 7.5583 -6.7026 13.4385
SNU-C1 GDSC2 -0.1667 2.3437 -4.1494 0.6999
SNU-81 GDSC2 -0.0564 2.7713 -4.2639 0.9789
COLO 678 GDSC2 0.1933 3.1559 -4.3053 0.9587
SNU-61 GDSC2 0.2573 2.385 -4.0051 0.2382
NCI-H716 GDSC2 0.4578 6.219 -5.4325 5.4313
SNU-1040 GDSC2 0.6803 2.231 -3.8123 0.0243
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 -4.6399 -0.3542 -6.009 21.0457
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC2 -5.3024 -2.4759 -5.7616 22.3565
JHH-4 GDSC2 -4.8795 -1.522 -5.7097 20.2925
SK-HEP-1 GDSC2 -3.1412 1.2677 -5.4679 12.9429
HuH-1 GDSC2 -2.94 2.0387 -5.691 13.6901
JHH-2 GDSC2 -2.4673 3.456 -6.0277 14.3176
JHH-1 GDSC2 -2.4333 0.7592 -4.6778 6.3108
JHH-6 GDSC2 -2.2758 2.2852 -5.3087 9.741
Hep-G2/C3A GDSC2 -2.0074 6.1213 -6.9978 18.0006
SNU-423 GDSC2 -1.7334 5.1393 -6.3128 14.0164
SNU-398 GDSC2 -1.6185 4.0869 -5.7208 10.6026
Hep 3B2.1-7 GDSC2 -0.9648 2.5675 -4.6118 3.3426
SNU-449 GDSC2 -0.84 2.5136 -4.5231 2.746
Huh-7 GDSC2 0.0173 2.2475 -4.0442 0.3726
JHH-7 GDSC2 0.2201 4.1529 -4.6822 2.316
SNU-387 GDSC2 0.293 2.72 -4.1083 0.4123
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 184 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1876 GDSC2 -8.6446 -5.9939 -8.6735 53.3041
NCI-H209 GDSC2 -7.9844 -5.9311 -7.997 46.8199
COR-L279 GDSC2 -7.1846 -6.0443 -7.1852 38.7649
NCI-H526 GDSC2 -7.106 -5.4139 -7.1172 38.0273
NCI-H1105 GDSC2 -6.9386 -5.2316 -6.9532 36.3648
NCI-H1155 GDSC2 -6.7942 -4.7845 -6.8344 35.0408
SBC-3 GDSC2 -6.76 -2.8485 -7.2132 36.4687
IST-SL2 GDSC2 -6.7372 -4.668 -6.786 34.5114
HCC78 GDSC2 -6.7187 -4.5435 -6.7808 34.3902
Lu-134-A GDSC2 -6.7155 -2.3841 -7.3182 36.6157
NCI-H460 GDSC2 -6.492 -4.8184 -6.5154 31.9295
COR-L311 GDSC2 -6.4891 -3.1474 -6.8275 33.4012
NCI-H1623 GDSC2 -6.3776 -3.6452 -6.5743 31.6416
NCI-H1048 GDSC2 -6.262 -3.3172 -6.5318 30.8547
COR-L32 GDSC2 -6.2277 -2.8171 -6.6441 31.2245
NCI-H2170 GDSC2 -6.2156 -4.3341 -6.2721 29.3243
EBC-1 GDSC2 -6.1895 -3.1723 -6.4935 30.3077
NCI-H748 GDSC2 -6.1459 -3.5656 -6.3408 29.3305
NCI-H1694 GDSC2 -5.8983 -3.9018 -5.9991 26.3711
LC-2/ad GDSC2 -5.7363 -4.0966 -5.7928 24.517
RERF-LC-MS GDSC2 -5.7198 -3.4727 -5.8992 24.9959
NCI-H2795 GDSC2 -5.6989 -2.1761 -6.2992 27.0046
NCI-H292 GDSC2 -5.6924 -3.6828 -5.82 24.4479
NCI-H2227 GDSC2 -5.6619 -2.353 -6.193 26.2849
NCI-H1734 GDSC2 -5.6388 -4.4452 -5.6538 23.3257
DMS 79 GDSC2 -5.5998 -2.889 -5.9383 24.6487
NCI-H1781 GDSC2 -5.5505 -3.1463 -5.8042 23.7016
NCI-H2081 GDSC2 -5.5297 -2.5765 -5.9693 24.4985
COLO 668 GDSC2 -5.5193 -3.1941 -5.7561 23.2983
SBC-5 GDSC2 -5.4414 -3.4163 -5.6099 22.1512
NCI-H2171 GDSC2 -5.4112 -2.6369 -5.82 23.1575
NCI-H211 GDSC2 -5.3201 -1.6841 -6.0957 24.2611
NCI-H2023 GDSC2 -5.3134 -2.1611 -5.8943 23.1369
A-549 GDSC2 -5.2033 -1.7802 -5.9334 22.8813
NCI-H1792 GDSC2 -5.2008 -1.5117 -6.0449 23.4808
NCI-H1651 GDSC2 -5.0872 -1.7789 -5.8129 21.7256
LOU-NH91 GDSC2 -5.0527 -0.6662 -6.2705 24.0752
NCI-H1341 GDSC2 -4.973 -2.8399 -5.2751 18.2002
NCI-H847 GDSC2 -4.8881 -0.0388 -6.3998 24.0882
DMS 53 GDSC2 -4.8326 -1.6845 -5.5901 19.418
NCI-H3122 GDSC2 -4.78 -1.6926 -5.5327 18.8751
NCI-H2087 GDSC2 -4.7473 -1.2243 -5.7094 19.7665
NCI-H2810 GDSC2 -4.7023 -1.0487 -5.7449 19.7953
COR-L95 GDSC2 -4.5935 -0.1701 -6.0519 21.1076
NCI-H2110 GDSC2 -4.5375 -2.2044 -5.0606 15.14
EMC-BAC-1 GDSC2 -4.4825 -1.265 -5.4266 17.0981
NCI-H2228 GDSC2 -4.453 -0.3773 -5.8177 19.2719
Lu-135 GDSC2 -4.4229 -1.0089 -5.4879 17.2385
NCI-H2196 GDSC2 -4.3869 -0.4421 -5.7233 18.4866
NCI-H1703 GDSC2 -4.3759 -1.7361 -5.1031 14.7623
SK-MES-1 GDSC2 -4.3723 -0.1899 -5.8309 19.0524
SK-LU-1 GDSC2 -4.3443 1.6879 -6.7227 23.6605
NCI-H82 GDSC2 -4.3363 -1.3265 -5.2537 15.5194
NCI-H1963 GDSC2 -4.2825 -0.4332 -5.6283 17.5554
HCC366 GDSC2 -4.2356 -0.3437 -5.6273 17.3823
NCI-H2122 GDSC2 -4.2246 -0.314 -5.6314 17.3675
DMS 273 GDSC2 -4.1758 -1.0243 -5.2418 14.8641
SW1573 GDSC2 -4.1748 0.2862 -5.8782 18.6202
NCI-H1944 GDSC2 -4.1693 0.4485 -5.9528 19.0226
NCI-H1648 GDSC2 -4.0814 -0.9462 -5.1899 14.2147
NCI-H647 GDSC2 -4.0776 0.2995 -5.7954 17.8106
COR-L303 GDSC2 -4.059 -1.7094 -4.8023 11.7593
NCI-H2373 GDSC2 -4.0576 0.239 -5.7473 17.4639
HOP-62 GDSC2 -4.0443 -0.3024 -5.4692 15.7773
NCI-H650 GDSC2 -3.9311 -0.7945 -5.1234 13.2897
NCI-H2804 GDSC2 -3.8836 0.1686 -5.5549 15.7478
PaCa-3 GDSC2 -3.8612 0.029 -5.4656 15.1398
NCI-H2461 GDSC2 -3.8166 1.8107 -6.3113 19.7872
Lu-65 GDSC2 -3.786 1.6892 -6.224 19.2232
NCI-H1793 GDSC2 -3.7818 -1.0513 -4.8601 11.1583
NCI-H2803 GDSC2 -3.7724 -0.5242 -5.112 12.6914
NCI-H1666 GDSC2 -3.7485 0.9342 -5.8151 16.8293
IA-LM GDSC2 -3.7258 -0.6 -5.0326 12.0482
ABC-1 GDSC2 -3.6811 -0.5428 -5.0211 11.8334
KNS-62 GDSC2 -3.6729 -0.4511 -5.0594 12.0444
NCI-H2009 GDSC2 -3.6613 1.6702 -6.1061 18.1833
HARA [Human squamous cell lung carcinoma] GDSC2 -3.6482 0.4962 -5.5092 14.7136
EMC-BAC-2 GDSC2 -3.6461 0.9399 -5.7287 16.0023
NCI-H146 GDSC2 -3.631 0.497 -5.4947 14.5725
Calu-6 GDSC2 -3.63 0.9358 -5.7126 15.8578
Lu-139 GDSC2 -3.534 0.9003 -5.6123 14.9693
NCI-H810 GDSC2 -3.4888 0.9821 -5.6145 14.8432
NCI-H290 GDSC2 -3.4484 0.4763 -5.3274 12.9977
HCC44 GDSC2 -3.3594 -0.5547 -4.7369 9.0631
NCI-H510A GDSC2 -3.3447 1.0415 -5.5227 13.8632
NCI-H23 GDSC2 -3.3132 1.1902 -5.5707 14.0551
PC-14 GDSC2 -3.2708 1.134 -5.5074 13.554
SW1271 GDSC2 -3.2439 1.6522 -5.7443 14.8664
IST-SL1 GDSC2 -3.1761 -0.4082 -4.6591 8.0476
NCI-H441 GDSC2 -3.106 1.3386 -5.4748 12.8841
COR-L23 GDSC2 -3.0695 0.7988 -5.1759 10.9718
NCI-H513 GDSC2 -3.0611 1.1981 -5.3684 12.1194
LCLC-97TM1 GDSC2 -3.0602 1.9429 -5.7396 14.3084
NCI-H446 GDSC2 -3.0588 2.6682 -6.1006 16.3313
Ms-1 GDSC2 -3.0503 1.7509 -5.6357 13.6773
NCI-H250 GDSC2 -3.0043 0.5176 -4.9839 9.6086
NCI-H1568 GDSC2 -2.9821 1.2014 -5.307 11.5299
NCI-H1975 GDSC2 -2.9556 2.0434 -5.7057 13.819
SBC-1 GDSC2 -2.9504 0.9337 -5.1486 10.4784
NCI-H1915 GDSC2 -2.9497 2.2831 -5.8206 14.4613
Lu-99A GDSC2 -2.9415 2.5884 -5.9663 15.2583
Calu-3 GDSC2 -2.9082 3.1361 -6.213 16.5097
NCI-H1299 GDSC2 -2.8941 2.8404 -6.0542 15.6112
NCI-H740 GDSC2 -2.871 2.8144 -6.0229 15.375
LB647-SCLC GDSC2 -2.8658 3.8589 -6.5397 18.0817
NCI-H1437 GDSC2 -2.8211 1.5688 -5.3635 11.4349
NCI-H2591 GDSC2 -2.812 1.2623 -5.2042 10.4495
NCI-H524 GDSC2 -2.767 3.8047 -6.434 17.2708
NCI-H838 GDSC2 -2.7628 0.1626 -4.623 6.7431
NCI-H1581 GDSC2 -2.756 2.847 -5.9484 14.6466
NCI-H322M GDSC2 -2.7038 0.994 -4.9889 8.8566
COR-L321 GDSC2 -2.5935 1.6402 -5.2252 10.0163
NCI-H2405 GDSC2 -2.5778 2.0195 -5.4007 11.0248
NCI-H1993 GDSC2 -2.5315 2.4854 -5.596 12.0522
HOP-92 GDSC2 -2.387 3.4826 -5.9799 13.8492
NCI-H520 GDSC2 -2.3821 2.6792 -5.5798 11.5823
NCI-H2135 GDSC2 -2.3258 1.7397 -5.0783 8.4876
NCI-H2347 GDSC2 -2.2313 2.3089 -5.2883 9.5163
NCI-H2595 GDSC2 -2.1981 1.2789 -4.7665 6.3346
NCI-H69 GDSC2 -2.1762 3.8573 -6.0072 13.4694
NCI-H2731 GDSC2 -2.1604 1.986 -5.0813 8.1294
NCI-H1838 GDSC2 -2.1476 1.8308 -4.9975 7.6027
NCI-H358 GDSC2 -2.0543 4.5038 -6.2352 14.3843
NCI-H1650 GDSC2 -1.9768 2.7368 -5.3167 9.1035
COR-L105 GDSC2 -1.931 2.1621 -5.0093 7.2102
Lu-165 GDSC2 -1.8973 3.782 -5.768 11.4893
NCI-H1869 GDSC2 -1.8376 1.6662 -4.7141 5.3059
NCI-H1693 GDSC2 -1.8001 3.762 -5.6897 10.8324
NCI-H2141 GDSC2 -1.6846 3.9989 -5.724 10.7651
A-427 GDSC2 -1.6593 7.1659 -7.2529 18.2834
NCI-H522 GDSC2 -1.648 4.1467 -5.77 10.9376
NCI-H1755 GDSC2 -1.5448 3.2326 -5.2629 7.8825
LXF 289 GDSC2 -1.5375 5.2818 -6.2426 13.2054
NCI-H2818 GDSC2 -1.4795 3.8638 -5.5197 9.1925
RERF-LC-Sq1 GDSC2 -1.366 6.0039 -6.4725 13.9786
NCI-H841 GDSC2 -1.3428 3.4906 -5.2539 7.4365
HCC15 GDSC2 -1.342 6.352 -6.6246 14.6679
NCI-H1092 GDSC2 -1.3386 3.2921 -5.1584 6.895
COR-L88 GDSC2 -1.3294 4.6266 -5.7834 10.3267
NCI-H3255 GDSC2 -1.2495 4.5145 -5.6768 9.5851
EPLC-272H GDSC2 -1.2264 4.1235 -5.4767 8.4459
LCLC-103H GDSC2 -1.117 5.9299 -6.2643 12.3943
HCC827 GDSC2 -1.0575 5.1154 -5.8355 10.0492
DMS 114 GDSC2 -0.9565 5.7845 -6.0868 11.1565
RERF-LC-KJ GDSC2 -0.9271 2.7121 -4.6544 3.5058
NCI-H2722 GDSC2 -0.8858 6.6205 -6.4387 12.7767
LC-1/sq GDSC2 -0.885 6.0539 -6.1675 11.4235
NCI-H1563 GDSC2 -0.8807 3.6465 -5.0433 5.467
NCI-H596 GDSC2 -0.8466 4.5058 -5.4157 7.4049
NCI-H661 GDSC2 -0.7913 2.8064 -4.6227 3.1676
CPC-N GDSC2 -0.7533 5.6527 -5.8917 9.748
NCI-H2342 GDSC2 -0.703 3.8947 -5.0521 5.2315
NCI-H64 GDSC2 -0.6495 3.8854 -5.0175 4.9692
NCI-H1355 GDSC2 -0.6191 3.4526 -4.8103 3.8689
SHP-77 GDSC2 -0.5657 4.6738 -5.3234 6.4339
BEN GDSC2 -0.4306 4.7539 -5.2807 5.995
NCI-H1435 GDSC2 -0.3429 3.7235 -4.7811 3.3682
NCI-H835 GDSC2 -0.2977 3.6366 -4.7213 3.0332
NCI-H1770 GDSC2 -0.2622 6.1087 -5.797 8.3674
NCI-H2291 GDSC2 -0.2434 5.5005 -5.5084 6.8658
CAL-12T GDSC2 -0.227 9.2286 -7.243 15.1106
NCI-H2029 GDSC2 -0.2205 10.1268 -7.67 16.8527
NCI-H226 GDSC2 -0.1978 5.7201 -5.581 7.1617
EKVX GDSC2 -0.1779 4.213 -4.9042 3.7505
NCI-H2085 GDSC2 -0.0893 3.2543 -4.465 1.7214
LK-2 GDSC2 -0.083 8.3979 -6.7523 12.6645
NCI-H2444 GDSC2 -0.0333 1.6346 -3.8531 0.0994
NCI-H196 GDSC2 0.0712 2.6786 -4.178 0.6635
NCI-H727 GDSC2 0.1058 4.498 -4.8798 3.2958
NCI-H2369 GDSC2 0.1116 3.6221 -4.5199 1.7645
NCI-H1836 GDSC2 0.1374 2.7717 -4.186 0.6536
NCI-H2066 GDSC2 0.2037 2.2114 -3.9649 0.1915
UMC-11 GDSC2 0.2255 3.5073 -4.4251 1.3312
HCC33 GDSC2 0.2269 1.9085 -3.8561 0.0741
NCI-H720 GDSC2 0.2295 2.9331 -4.2087 0.6702
VMRC-LCD GDSC2 0.2367 4.3198 -4.7421 2.5504
NCI-H2030 GDSC2 0.3184 7.1282 -5.9153 7.9898
NCI-H1573 GDSC2 0.366 2.2441 -3.9201 0.1139
NCI-H2869 GDSC2 0.3813 3.57 -4.3833 1.0919
NCI-H1688 GDSC2 0.4248 2.7772 -4.0801 0.3197
NCI-H1436 GDSC2 0.445 2.4518 -3.9624 0.1471
NCI-H345 GDSC2 0.484 2.3971 -3.9309 0.1097
ChaGo-K-1 GDSC2 0.599 2.8301 -4.0364 0.2122
NCI-H2172 GDSC2 0.6119 2.2795 -3.8501 0.0426
⏷ Show the Full List of 184 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 -3.5911 0.1392 -5.2816 13.1567
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-15 GDSC2 -5.6398 -2.8188 -6.0048 25.1883
KYSE-270 GDSC2 -4.7455 -2.6042 -5.1171 16.3253
EC-GI-10 GDSC2 -4.5572 -0.9366 -5.6535 18.7126
TE-10 GDSC2 -4.4358 -0.0046 -5.9807 20.1294
TE-11 GDSC2 -4.3498 -1.0243 -5.4095 16.5029
TE-5 GDSC2 -4.0497 -0.9841 -5.1415 13.8084
KYSE-510 GDSC2 -3.8929 -2.0699 -4.4701 9.1195
OE33 GDSC2 -3.855 -0.4225 -5.2367 13.7305
KYSE-150 GDSC2 -3.6956 1.3238 -5.9631 17.4997
TE-8 GDSC2 -2.8901 2.099 -5.6815 13.4978
T.T GDSC2 -2.764 1.2287 -5.1506 9.9987
TE-1 GDSC2 -2.6772 1.2947 -5.1175 9.5751
OE21 GDSC2 -2.5592 1.0918 -4.9299 8.1399
TE-9 GDSC2 -2.2292 1.4521 -4.871 7.0267
KYSE-450 GDSC2 -1.4957 3.6783 -5.4421 8.7926
KYSE-410 GDSC2 -1.2787 2.5933 -4.8001 4.805
TE-4 GDSC2 -1.2183 3.0394 -4.9675 5.6197
KYSE-520 GDSC2 -1.0149 1.6774 -4.2611 1.7409
COLO 680N GDSC2 -0.635 4.9969 -5.5125 7.5455
KYSE-70 GDSC2 -0.4067 3.9674 -4.9196 4.1246
KYSE-140 GDSC2 -0.4017 4.9339 -5.345 6.2807
KYSE-180 GDSC2 -0.0384 6.4486 -5.8178 8.0918
TE-6 GDSC2 0.1796 3.2698 -4.3539 1.1235
OE19 GDSC2 0.4917 2.6536 -4.0141 0.2026
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OC 314 GDSC2 -5.7009 -4.1316 -5.7502 24.1244
TOV-112D GDSC2 -5.6702 -4.1128 -5.72 23.8189
ES-2 GDSC2 -5.5286 -2.3654 -6.0454 24.903
Caov-3 GDSC2 -5.4838 -3.8136 -5.5675 22.1259
TYK-nu GDSC2 -5.3288 -1.7627 -6.072 24.1711
DOV13 GDSC2 -5.1792 -2.9969 -5.4461 20.0637
A2780 GDSC2 -5.0485 -0.9678 -6.1292 23.307
OAW42 GDSC2 -4.8868 -0.8328 -6.0282 22.1085
OVCAR-8 GDSC2 -4.2854 -0.5455 -5.5768 17.2628
Caov-4 GDSC2 -4.0141 -0.1299 -5.526 16.014
OAW28 GDSC2 -3.4191 1.1972 -5.663 14.9161
OV56 GDSC2 -3.3535 -1.2017 -4.4085 6.9717
JHOS-4 GDSC2 -3.2605 5.6446 -7.7541 24.5941
SK-OV-3 GDSC2 -3.1679 1.0946 -5.4032 12.6313
OVK18 GDSC2 -2.9847 2.8945 -6.1538 16.4081
IGROV-1 GDSC2 -2.9743 2.5994 -5.9981 15.5275
JHOS-2 GDSC2 -2.9066 0.9091 -5.1021 10.0757
TOV-21G GDSC2 -2.6529 3.5018 -6.1935 15.7032
OV-90 GDSC2 -2.6109 2.621 -5.7237 12.9924
OVCAR-3 GDSC2 -2.4871 1.7182 -5.1846 9.5089
RMG-I GDSC2 -2.4189 2.0531 -5.2991 10.027
EFO-21 GDSC2 -1.9105 2.3824 -5.1009 7.7027
OVCAR-5 GDSC2 -1.5568 3.3586 -5.3305 8.2895
OVISE GDSC2 -1.1953 3.1137 -4.9876 5.6905
Kuramochi GDSC2 -0.4171 3.2341 -4.6125 2.6694
OVCAR-4 GDSC2 -0.3911 3.624 -4.7637 3.3447
EFO-27 GDSC2 -0.3783 5.5258 -5.5999 7.5584
OVKATE GDSC2 -0.2953 3.8411 -4.8066 3.4309
FU-OV-1 GDSC2 0.0311 2.9923 -4.3109 1.0786
OVTOKO GDSC2 0.1139 4.9823 -5.0811 4.2246
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 GDSC2 -5.9316 -3.3784 -6.1547 27.3402
CFPAC-1 GDSC2 -5.4022 -1.5951 -6.2188 25.2685
KP-4 GDSC2 -5.1645 -2.7366 -5.5183 20.3999
Capan-1 GDSC2 -4.8723 -1.1515 -5.8683 21.1622
MIA PaCa-2 GDSC2 -4.3948 -1.2335 -5.3548 16.342
SUIT-2 GDSC2 -4.0944 1.28 -6.2945 20.6282
PL4 GDSC2 -4.0591 -0.2754 -5.496 15.9885
PSN1 GDSC2 -3.8786 -0.0114 -5.4612 15.1711
Panc 10.05 GDSC2 -3.8118 -1.2511 -4.7893 10.8169
Panc 02.03 GDSC2 -3.7489 -0.218 -5.2427 13.4195
KP-1N GDSC2 -3.5792 -0.4064 -4.9993 11.3753
Panc 03.27 GDSC2 -3.4429 -0.2773 -4.9462 10.6253
DAN-G GDSC2 -3.2639 0.2269 -5.0482 10.7333
YAPC GDSC2 -3.2395 0.3567 -5.093 10.9406
HuP-T3 GDSC2 -3.2107 -0.7393 -4.5218 7.2783
HPAF-II GDSC2 -2.5118 1.3309 -5.0126 8.5295
PaTu 8988t GDSC2 -2.4987 1.916 -5.2905 10.1717
Panc 04.03 GDSC2 -2.4415 1.5363 -5.0621 8.6616
SW1990 GDSC2 -2.2636 2.8165 -5.56 11.1782
MZ-PC-1 GDSC2 -2.0417 2.0995 -5.0542 7.7085
PaTu 8902 GDSC2 -1.5433 4.9977 -6.1088 12.5235
KP-2 GDSC2 -1.3716 2.6739 -4.8925 5.471
Hs 766T GDSC2 -1.338 4.1743 -5.5736 9.2007
BxPC-3 GDSC2 -1.3367 3.9214 -5.4528 8.5316
HPAC GDSC2 -0.64 4.6417 -5.3528 6.7123
SU.86.86 GDSC2 -0.3791 2.4441 -4.276 1.2428
QGP-1 GDSC2 -0.0481 6.5894 -5.888 8.458
Panc 08.13 GDSC2 0.2488 3.0574 -4.2465 0.7617
Capan-2 GDSC2 0.493 2.948 -4.1146 0.3629
KP-3 GDSC2 0.5248 3.261 -4.2132 0.5565
AsPC-1 GDSC2 0.7202 4.4253 -4.5658 1.4694
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC2 -4.2205 0.0507 -5.8053 18.3634
IST-Mes1 GDSC2 -3.8615 -1.3016 -4.8108 11.1185
NCI-H2052 GDSC2 -3.4611 1.6915 -5.9455 16.6666
MPP 89 GDSC2 -3.077 1.7458 -5.6547 13.8641
NCI-H28 GDSC2 -2.2668 3.2075 -5.7545 12.2944
NCI-H2452 GDSC2 -0.2904 5.9866 -5.758 8.218
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC2 -5.1011 -1.6604 -5.8777 22.1451
LNCaP clone FGC GDSC2 -4.9665 0.0206 -6.5044 24.927
22Rv1 GDSC2 -4.8361 -1.4569 -5.6943 20.0309
VCaP GDSC2 -3.2681 1.3497 -5.613 14.1715
PC-3 GDSC2 -3.2397 0.3878 -5.1087 11.0386
NCI-H660 GDSC2 -0.2348 1.2511 -3.7942 0.0703
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 -4.5178 -1.8051 -5.2152 15.9772
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-375 GDSC2 -6.4841 -3.4803 -6.731 32.9327
RPMI-7951 GDSC2 -5.9644 -2.9646 -6.3107 28.3012
UACC-62 GDSC2 -5.7131 -2.8197 -6.0841 25.9458
DJM-1 GDSC2 -5.2374 -1.5574 -6.0632 23.7341
MZ-MEL-2 GDSC2 -5.0857 -0.1697 -6.5326 25.5457
IGR-37 GDSC2 -4.9731 -2.5101 -5.3961 18.8846
A-388 GDSC2 -4.8419 -1.9968 -5.4653 18.7346
IST-MEL1 GDSC2 -4.7037 -2.4143 -5.1475 16.3253
WM793 GDSC2 -4.6404 -0.9621 -5.7236 19.4347
G-mel GDSC2 -4.6253 -2.1649 -5.1686 16.1282
SK-MEL-24 GDSC2 -4.5055 -1.1099 -5.5215 17.7459
Hs 940.T GDSC2 -4.2153 -0.4882 -5.5381 16.7839
M14 GDSC2 -4.1714 0.1014 -5.7845 18.0717
A-431 GDSC2 -4.1559 1.5074 -6.4625 21.712
A101D GDSC2 -4.0705 -0.0066 -5.6384 16.8718
LOX-IMVI GDSC2 -4.0382 -0.017 -5.6036 16.5564
WM278 GDSC2 -3.9149 -0.0449 -5.4775 15.3894
WT2-iPS GDSC2 -3.7967 0.1314 -5.4586 14.8863
SK-MEL-5 GDSC2 -3.6663 -0.4149 -5.0715 12.0986
COLO 679 GDSC2 -3.5524 0.0736 -5.2153 12.6299
COLO 783 GDSC2 -3.5154 -1.3548 -4.471 7.8575
A2058 GDSC2 -3.3996 2.0043 -6.0501 17.0612
COLO 800 GDSC2 -3.3289 -0.0176 -4.9799 10.4971
SK-MEL-28 GDSC2 -3.2836 -0.6384 -4.6319 8.1802
IPC-298 GDSC2 -3.2493 3.3833 -6.6142 19.5642
SK-MEL-1 GDSC2 -3.2049 3.2392 -6.5055 18.8882
COLO 829 GDSC2 -2.9773 2.7438 -6.0726 15.9455
HT-144 GDSC2 -2.9557 2.3313 -5.8494 14.6419
MMAc-SF GDSC2 -2.8713 1.1463 -5.1924 10.5345
HMV-II GDSC2 -2.7946 2.2588 -5.6859 13.2633
WM115 GDSC2 -2.7841 1.7421 -5.4209 11.6801
CHL-1 GDSC2 -2.7098 1.069 -5.0305 9.1263
MZ-MEL-7 GDSC2 -2.6398 0.7187 -4.8058 7.5737
SK-MEL-3 GDSC2 -2.3956 1.94 -5.2265 9.5388
SH-4 GDSC2 -2.3674 4.0503 -6.2459 15.2275
WM1552C GDSC2 -2.2057 4.3991 -6.2963 15.0785
Hs 938.T GDSC2 -2.0262 7.1007 -7.4967 20.2137
CP50-MEL-B GDSC2 -1.7991 5.847 -6.7075 16.1306
GAK GDSC2 -1.6986 3.6311 -5.5562 9.8611
Mel Ho GDSC2 -1.6359 2.5474 -4.9986 6.5564
UACC-257 GDSC2 -1.364 2.5369 -4.8251 5.0852
G-361 GDSC2 -1.1467 5.5712 -6.1124 11.6814
SK-MEL-31 GDSC2 -1.0916 8.8816 -7.6795 18.742
WM35 GDSC2 -1.0486 4.796 -5.6788 9.1958
IGR-1 GDSC2 -0.8991 4.7863 -5.5786 8.3735
Mel JuSo GDSC2 -0.8672 4.9426 -5.6315 8.5961
451Lu GDSC2 -0.8249 5.5425 -5.886 9.856
CP66-MEL GDSC2 -0.6724 4.196 -5.1698 5.8008
SK-MEL-30 GDSC2 -0.6611 3.8857 -5.0242 5.0216
RVH-421 GDSC2 -0.4136 5.1563 -5.4525 6.8564
SK-MEL-2 GDSC2 -0.3554 1.1145 -3.7896 0.0792
VMRC-MELG GDSC2 -0.3201 2.2432 -4.1742 0.8605
LB2518-MEL GDSC2 -0.2921 4.9098 -5.2712 5.7315
COLO 792 GDSC2 -0.1943 4.8234 -5.1781 5.1171
MeWo GDSC2 -0.1561 5.0351 -5.2502 5.423
LB373-MEL-D GDSC2 0.064 5.528 -5.3454 5.577
EquiPSC Line K2 GDSC2 -0.4183 10.7119 -8.0909 18.8684
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 -6.2237 -3.7065 -6.3926 29.974
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYM-1 GDSC2 -6.9319 -4.7564 -6.9823 36.4665
EW-8 GDSC2 -6.5452 -5.0816 -6.5556 32.3981
SW872 GDSC2 -5.9919 -3.6264 -6.1586 27.6495
Hs 633.T GDSC2 -5.8288 -2.2693 -6.4033 28.1313
SW982 GDSC2 -5.7631 -1.0089 -6.843 29.9241
SK-LMS-1 GDSC2 -5.4585 -1.3964 -6.3614 26.252
VA-ES-BJ GDSC2 -5.4182 -3.17 -5.6529 22.2767
G-401 GDSC2 -5.2873 -0.8488 -6.4246 25.8393
SK-UT-1 GDSC2 -4.9519 -1.8378 -5.6471 20.2293
G-402 GDSC2 -4.6911 -0.0395 -6.2082 22.3241
GCT GDSC2 -4.6 -0.9477 -5.6904 19.0891
TE 441.T GDSC2 -4.5771 0.7067 -6.4586 23.2008
MES-SA GDSC2 -4.3495 -0.3436 -5.7351 18.4188
STS-0421 GDSC2 -3.7455 0.5297 -5.6112 15.6307
MFH-ino GDSC2 -3.6754 0.4123 -5.4913 14.6923
A-204 GDSC2 -3.3966 2.3468 -6.2188 17.9696
Rh41 GDSC2 -3.2598 0.0374 -4.9501 10.1105
RKN GDSC2 -2.5315 0.6875 -4.7122 6.7432
Rh30 GDSC2 -2.0357 2.1524 -5.0755 7.8211
HT-1080 GDSC2 -1.744 3.2327 -5.3957 9.0509
Rh18 GDSC2 -0.279 10.192 -7.7418 17.2545
RD GDSC2 -0.109 6.4131 -5.8439 8.3411
SW684 GDSC2 -0.0069 4.3138 -4.8592 3.3316
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC2 -6.9384 -4.528 -7.0167 36.6576
SNU-5 GDSC2 -6.9362 -6.0229 -6.9364 36.2705
NUGC-3 GDSC2 -6.2202 -4.0675 -6.317 29.5751
RF-48 GDSC2 -5.6459 -1.4785 -6.5222 27.886
SNU-1 GDSC2 -4.8232 -1.8026 -5.529 19.0273
AGS GDSC2 -4.8105 -1.1038 -5.8277 20.6889
SNU-16 GDSC2 -4.5866 -1.3256 -5.502 17.9394
ECC10 GDSC2 -4.5767 -1.8445 -5.2577 16.4594
23132/87 GDSC2 -4.1608 -0.9381 -5.269 14.9759
MKN45 GDSC2 -3.8693 -0.9624 -4.9841 12.2207
OCUM-1 GDSC2 -3.8021 0.4046 -5.5991 15.7422
GCIY GDSC2 -3.7888 0.7403 -5.7542 16.6077
HGC-27 GDSC2 -3.3256 0.7284 -5.3502 12.7687
RERF-GC-1B GDSC2 -3.2655 0.0174 -4.9448 10.0939
NCI-N87 GDSC2 -3.2482 0.5426 -5.1931 11.5836
TGBC11TKB GDSC2 -2.9489 0.4523 -4.9079 8.9889
MKN1 GDSC2 -2.267 2.7326 -5.5214 10.9632
TMK-1 GDSC2 -1.5048 2.0929 -4.7067 4.6692
IM95 GDSC2 -1.2848 2.8227 -4.9082 5.408
Hs 746.T GDSC2 -1.0851 6.0178 -6.2847 12.4301
NUGC-4 GDSC2 -0.6572 6.8697 -6.4047 12.1442
SK-GT-2 GDSC2 -0.5975 2.9984 -4.6042 2.8392
MKN7 GDSC2 -0.5603 2.1987 -4.2601 1.3245
MKN28 GDSC2 -0.5599 3.2334 -4.6846 3.1756
Fu97 GDSC2 -0.4828 6.6235 -6.1744 10.6682
ECC12 GDSC2 -0.2336 8.0488 -6.6854 12.6455
KATO III GDSC2 0.0806 3.7284 -4.5763 2.0131
SCH GDSC2 0.5755 10.4557 -7.2965 13.8114
SNG-M GDSC2 -2.8978 2.0287 -5.6525 13.3509
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 -6.8536 -5.0216 -6.8773 35.5567
CAL-62 GDSC2 -5.9884 -2.8929 -6.3595 28.6636
FTC-133 GDSC2 -5.668 -3.5088 -5.8338 24.4055
BHT-101 GDSC2 -5.2811 -1.3438 -6.2003 24.6523
8505C GDSC2 -4.527 -1.2775 -5.4649 17.4934
ASH-3 GDSC2 -4.3126 -2.0576 -4.8938 13.2636
KMH-2 GDSC2 -4.0152 -1.0146 -5.0943 13.3991
B-CPAP GDSC2 -3.9753 -0.6939 -5.2136 13.9931
ML-1 [Human leukemia] GDSC2 -3.8375 1.4301 -6.1402 18.9392
CGTH-W-1 GDSC2 -3.6069 0.1491 -5.3003 13.3201
K5 GDSC2 -3.2196 3.0614 -6.4287 18.5399
HTC-C3 GDSC2 -3.1404 -0.1458 -4.7614 8.5916
TT2609-C02 GDSC2 -3.0455 1.9587 -5.7356 14.2436
8305C GDSC2 -2.6822 1.0595 -5.005 8.901
TT GDSC2 -2.6012 4.1667 -6.4838 17.072
WRO GDSC2 -1.0986 5.6423 -6.1139 11.5883
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAS GDSC2 -7.0248 -5.0563 -7.0531 37.2938
HSC-2 GDSC2 -6.5815 -4.769 -6.6126 32.8653
HO-1-N-1 GDSC2 -6.2964 -4.3177 -6.3603 30.1718
FaDu GDSC2 -6.1249 -3.5802 -6.3145 29.0944
BB30-HNC GDSC2 -5.9162 -3.9906 -6.0026 26.4764
HSC-3 GDSC2 -5.877 -3.3737 -6.0964 26.7768
BICR 22 GDSC2 -5.5419 -3.7904 -5.6347 22.7561
CAL-33 GDSC2 -5.4736 -3.1081 -5.7318 22.9577
CAL-27 GDSC2 -5.4586 -2.0827 -6.0793 24.774
JHU-011 GDSC2 -5.272 -3.3344 -5.4467 20.4878
Ca9-22 GDSC2 -5.2681 -2.1943 -5.8331 22.6039
PCI-04B GDSC2 -5.1232 -3.0128 -5.3801 19.4489
PCI-15A GDSC2 -5.0053 -3.0853 -5.2288 18.0851
JHU-029 GDSC2 -4.9435 -1.4431 -5.81 21.1201
HSC-4 GDSC2 -4.8307 -2.1266 -5.399 18.3058
KON GDSC2 -4.7153 -1.3345 -5.6271 19.1666
KOSC-2 GDSC2 -4.5395 0.8973 -6.5159 23.3513
SCC-15 GDSC2 -4.2487 0.3104 -5.9584 19.3329
OSC-20 GDSC2 -4.1925 -1.1333 -5.2056 14.7041
JHU-022 GDSC2 -4.096 -1.0064 -5.1745 14.1724
SCC-4 GDSC2 -3.8511 -0.712 -5.0905 12.818
Detroit 562 GDSC2 -3.8142 0.8825 -5.8473 17.227
DOK GDSC2 -3.6004 1.736 -6.0866 17.8838
OSC-19 GDSC2 -3.5808 0.774 -5.5895 14.9797
BICR 78 GDSC2 -3.5513 0.2815 -5.3182 13.2566
PE/CA-PJ15 GDSC2 -3.3548 -0.7369 -4.6419 8.4507
PCI-30 GDSC2 -3.1706 0.7874 -5.2519 11.7211
BHY GDSC2 -3.0489 0.5722 -5.0464 10.1174
HO-1-u-1 GDSC2 -2.8525 2.5445 -5.8737 14.4929
BICR 10 GDSC2 -2.5806 2.7224 -5.7507 13.0676
BB49-HNC GDSC2 -2.3995 6.0365 -7.2563 20.1579
NCI-H3118 GDSC2 -2.3214 3.2524 -5.8171 12.7814
PCI-06A GDSC2 -2.2594 3.9228 -6.1014 14.1849
SKN-3 GDSC2 -1.9665 2.0177 -4.9642 7.0191
BICR 31 GDSC2 -1.844 1.5315 -4.6554 4.98
LB771-HNC GDSC2 -0.6447 3.2295 -4.7273 3.4912
SAT [Human HNSCC] GDSC2 -0.2532 4.2069 -4.9412 4.026
UPCI-SCC-090 GDSC2 -0.2523 4.633 -5.1264 4.941
SCC-9 GDSC2 0.1478 7.7276 -6.2925 10.0934
SCC-25 GDSC2 0.5545 3.2363 -4.1932 0.5008
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC2 -7.4248 -6.489 -7.4249 41.1734
647V GDSC2 -6.8645 -4.769 -6.9099 35.7695
BFTC-905 GDSC2 -6.4482 -3.7247 -6.6327 32.2828
UM-UC-3 GDSC2 -5.7983 -3.2314 -6.0497 26.1603
CAL-29 GDSC2 -5.5013 -3.2799 -5.7119 22.9772
KU-19-19 GDSC2 -4.9062 -1.3756 -5.8019 20.9238
J82 GDSC2 -4.6605 -1.4214 -5.5324 18.4029
RT-4 GDSC2 -4.4524 -1.5773 -5.2524 15.9477
T24 GDSC2 -3.8322 -1.2998 -4.7844 10.8549
5637 GDSC2 -3.506 0.3314 -5.3042 13.0313
TCCSUP GDSC2 -3.3711 1.3493 -5.6986 14.9791
SW780 GDSC2 -2.6801 1.8712 -5.4049 11.3121
HT-1197 GDSC2 -2.0311 4.1301 -6.0346 13.2632
SW1710 GDSC2 -0.8686 3.3086 -4.8847 4.6093
RT-112 GDSC2 -0.0176 5.7766 -5.5018 6.4768
HT-1376 GDSC2 0.7363 3.2019 -4.1147 0.2987
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC2 -6.4697 -4.4019 -6.5338 31.9085
NT2-D1 GDSC2 -5.8763 -1.7588 -6.6507 29.5607
NEC8 GDSC2 -5.8467 -4.2569 -5.8896 25.5548
BPH-1 GDSC2 -5.7439 -3.1002 -6.0289 25.7962
KGN GDSC2 -5.6031 -1.2916 -6.5562 27.8608
SW954 GDSC2 -5.5956 -1.5431 -6.4427 27.2669
JEG-3 GDSC2 -5.5443 -0.0562 -7.0421 29.8223
CAL-39 GDSC2 -5.3546 -2.6534 -5.7531 22.5395
HT-3 GDSC2 -5.3045 -3.237 -5.5094 20.9772
PWR-1E GDSC2 -5.2594 -2.2472 -5.8031 22.3998
ACC-OV7 GDSC2 -5.233 -1.913 -5.9094 22.8752
ME-180 GDSC2 -5.1498 -2.9565 -5.4273 19.829
Ca Ski GDSC2 -4.8934 -2.1495 -5.4552 18.8881
DSH1 GDSC2 -4.7732 -2.3573 -5.2439 17.1717
C-33 A GDSC2 -4.7239 -0.8622 -5.8526 20.4918
UWB1.289 GDSC2 -4.5945 -0.3317 -5.9757 20.6895
PA-1 GDSC2 -4.5807 0.3673 -6.2978 22.3835
SiSo GDSC2 -4.2592 -1.3107 -5.1858 14.8263
LB831-BLC GDSC2 -4.2159 0.0854 -5.8179 18.4199
HEY GDSC2 -4.0147 -0.6607 -5.2664 14.45
MS751 GDSC2 -3.9866 -0.8293 -5.1578 13.6903
DoTc2 4510 GDSC2 -3.9167 -0.4813 -5.264 14.103
PEO1 GDSC2 -3.8878 -0.6806 -5.1395 13.2427
SW756 GDSC2 -3.8227 1.2117 -6.0185 18.2209
C-4-I GDSC2 -3.2084 1.3825 -5.5803 13.8041
JHOS-3 GDSC2 -3.0342 0.337 -4.9175 9.277
JAR GDSC2 -2.9056 2.2548 -5.7714 14.058
SKG-IIIa GDSC2 -2.5855 4.1868 -6.4816 17.0181
OVCA433 GDSC2 -2.5261 3.5141 -6.1014 14.8712
SKN GDSC2 -2.21 3.8618 -6.0345 13.7006
OMC-1 [Human cervical carcinoma] GDSC2 -1.1571 2.0244 -4.4794 2.9362
SiHa GDSC2 -0.801 4.5373 -5.4022 7.2516
HeLa GDSC2 -0.3755 5.1412 -5.4233 6.6427
OV17R GDSC2 -0.3354 6.4003 -5.9768 9.4053
OVMIU GDSC2 -0.0979 5.1899 -5.2862 5.518
HEC-1 GDSC2 -0.0813 2.224 -4.0728 0.469
OVCA420 GDSC2 0.1402 4.6051 -4.9074 3.3822
SW962 GDSC2 0.2465 2.3358 -3.9921 0.2212
NCC-IT GDSC2 0.5121 2.6068 -3.9912 0.1699
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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