Details of the Drug

General Information of Drug (ID: DM8Y4JS)

Drug Name
Quizartinib
Synonyms AC220
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Approved [1]
leukaemia 2A60-2B33 Phase 3 [2]
ATC Code
L01EX11: Quizartinib
L01EX: Other protein kinase inhibitors
L01E: PROTEIN KINASE INHIBITORS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 560.7
Logarithm of the Partition Coefficient (xlogp) 5.6
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C29H32N6O4S
IUPAC Name
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
Canonical SMILES
CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
InChI
InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
InChIKey
CVWXJKQAOSCOAB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24889392
ChEBI ID
CHEBI:90217
CAS Number
950769-58-1
UNII
7LA4O6Q0D3
DrugBank ID
DB12874
TTD ID
D07KYT
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fms-like tyrosine kinase 3 (FLT-3) TTGJCWZ FLT3_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Gene/Protein Processing [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Gene/Protein Processing [4]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Gene/Protein Processing [4]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [5]
DNA repair protein RAD51 homolog 1 (RAD51) OTNVWGC1 RAD51_HUMAN Gene/Protein Processing [5]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Post-Translational Modifications [5]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fms-like tyrosine kinase 3 (FLT-3) DTT FLT3 2.11E-01 -0.05 -0.16
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 1.9152 3.9436 -0.664 1.4138
EW-7 GDSC1 -0.4063 2.6992 -1.6811 15.1291
ES7 GDSC1 -0.0178 3.9742 -1.9793 15.7846
HuO9 GDSC1 0.5132 8.4597 -3.7863 24.3007
EW-1 GDSC1 0.5215 3.4899 -1.3063 8.9017
ES6 GDSC1 0.545 3.0999 -1.0966 7.2209
ES8 GDSC1 0.7562 3.3945 -1.0889 6.5489
ES1 GDSC1 0.7795 2.5141 -0.6533 3.243
ES5 GDSC1 0.8953 4.9845 -1.7652 11.1624
SK-PN-DW GDSC1 1.0491 3.5146 -0.9504 4.7626
CADO-ES1 GDSC1 1.0973 6.4436 -2.3334 14.4329
EW-3 GDSC1 1.1023 5.215 -1.729 10.2981
TC-71 GDSC1 1.149 4.4031 -1.3056 7.1068
NOS-1 [Human HNSCC] GDSC1 1.1709 6.798 -2.4535 14.9764
EW-18 GDSC1 1.3551 4.4198 -1.1798 5.6931
ES4 GDSC1 1.4558 3.5752 -0.739 2.4861
EW-11 GDSC1 1.4739 4.995 -1.3735 6.7878
EW-13 GDSC1 1.7055 4.4363 -0.9795 3.5917
EW-24 GDSC1 1.7197 2.8547 -0.3336 0.2425
CHSA8926 GDSC1 1.7932 3.5796 -0.5748 1.1057
H-EMC-SS GDSC1 1.8187 5.4791 -1.3839 6.0767
HuO-3N1 GDSC1 1.8367 8.0414 -2.585 13.8894
EW-16 GDSC1 1.8402 4.5431 -0.9525 3.1823
CHSA0011 GDSC1 2.0975 6.6749 -1.7647 8.018
CAL-72 GDSC1 2.4507 3.8913 -0.4284 0.203
NY GDSC1 2.6233 4.68 -0.6436 0.7139
CHSA0108 GDSC1 3.0534 5.3451 -0.7172 0.7015
SJSA-1 GDSC1; CTRP2 3.736 6.2735 3.4591 16.3561
Hs 822.T CTRP2 3.9256 6.4105 3.6227 15.1921
Hs 888.T CTRP2 4.7572 7.376 4.1395 10.8968
A-673 GDSC1; CTRP2 5.4847 8.7896 4.1814 8.9818
SaOS-2 GDSC1; CTRP2 5.6741 7.4254 5.0253 5.0563
SK-ES-1 GDSC1; CTRP2 6.2311 11.6131 3.414 10.6684
SK-N-MC CTRP2 7.2692 8.1105 5.7713 0.102
U2OS GDSC1; CTRP2 7.913 15.2413 2.8948 9.8975
MG-63 GDSC1; CTRP2 7.9521 9.8312 5.4069 0.5815
TC71 CTRP2 8.1172 11.4304 4.8196 2.265
CAL-78 GDSC1; CTRP2 8.2711 10.0646 5.4524 0.3442
G-292 clone A141B1 GDSC1; CTRP2 8.7628 10.8324 5.3656 0.3407
MHH-ES-1 GDSC1; CTRP2 9.3753 16.1758 3.4119 5.9936
HOS GDSC1; CTRP2 9.4528 19.1082 2.088 10.648
SW1353 CTRP2 14.2708 30.5193 -0.2069 11.9209
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 204 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 5.6693 9.1955 4.1463 8.7322
JK1 CTRP2 7.8819 12.358 4.256 4.6189
JM1 GDSC1; CTRP2 4.777 9.5079 3.1691 14.7529
EoL-1 GDSC1; CTRP2 -11.6109 -1.1679 -11.837 86.415
MV4-11 GDSC1; CTRP2 -9.8104 -4.1742 -9.821 90.7728
MOLM-13 GDSC1; CTRP2 -9.4971 -5.932 -9.4973 94.1336
NKM-1 GDSC1 -7.935 -2.4224 -8.1362 79.3516
Kasumi-1 GDSC1; CTRP2 -6.766 1.6389 -7.0257 74.8484
ALL-PO GDSC1 -5.2259 -0.7903 -5.504 61.7703
KMS-34 CTRP2 -0.7605 1.7945 -0.7672 45.351
KMS-18 CTRP2 -0.5865 2.214 -0.6004 44.2105
SEM CTRP2 -0.5377 34.4957 -13.9805 48.5794
KMS-20 CTRP2 -0.405 4.03 -0.564 43.3147
KMS-28BM CTRP2 -0.3107 8.0845 -1.5386 44.242
KMOE-2 GDSC1 -0.2849 1.649 -1.0524 9.7983
Mono-Mac-6 GDSC1; CTRP2 -0.0627 145.0287 -68.6004 49.4713
Loucy GDSC1 -0.0114 1.2714 -0.6228 5.3492
KOPN-8 GDSC1 0.0552 1.2883 -0.5754 4.7326
CA46 GDSC1 0.2042 2.0118 -0.8167 6.1196
697 GDSC1 0.2144 1.4785 -0.5438 3.946
BE-13 GDSC1 0.2861 2.609 -1.0498 7.6737
EB2 GDSC1 0.2886 3.1941 -1.3391 9.9117
CESS GDSC1 0.3341 1.8462 -0.6357 4.2916
WIL2 NS GDSC1 0.4159 2.0057 -0.6544 4.1945
SU-DHL-5 GDSC1 0.462 2.701 -0.9617 6.4311
A3/Kawakami GDSC1 0.4811 1.5376 -0.3857 2.0004
KG-1 GDSC1 0.487 3.1932 -1.1856 8.0842
Sc-1 GDSC1 0.6459 2.3534 -0.6638 3.644
HC-1 GDSC1 0.6549 6.9098 -2.901 19.3154
MY-M12 GDSC1 0.6672 4.8243 -1.8559 12.5206
LC4-1 GDSC1 0.6798 5.1599 -2.0125 13.5852
GR-ST GDSC1 0.6845 2.8529 -0.8769 5.1422
BL-41 GDSC1 0.7007 4.0309 -1.4395 9.3583
Karpas-45 GDSC1 0.7274 4.7585 -1.778 11.7704
YT GDSC1 0.7877 3.5684 -1.1511 6.931
BALL-1 GDSC1 0.878 3.669 -1.1371 6.5773
ARH-77 GDSC1 0.9577 2.5863 -0.5792 2.3427
QIMR-WIL GDSC1 0.9783 3.0131 -0.7613 3.5656
ML-2 GDSC1 0.9959 2.5628 -0.5471 2.0575
BC-1 GDSC1 1.0374 4.1333 -1.2516 7.0018
P32/ISH GDSC1 1.0481 2.9013 -0.6685 2.7703
JSC-1 GDSC1 1.1067 5.6578 -1.9416 11.7793
TUR GDSC1 1.1206 3.8541 -1.064 5.4162
MOLT-4 GDSC1 1.1249 4.3836 -1.3124 7.2191
SUP-M2 GDSC1 1.1298 7.9129 -3.0335 18.529
Ramos.2G6.4C10 GDSC1 1.1554 2.7279 -0.5329 1.6959
Farage GDSC1 1.1938 2.5329 -0.4321 1.0591
HAL-01 GDSC1 1.2337 8.0971 -3.0464 18.2813
Daudi GDSC1; CTRP2 1.2555 4.3923 1.1591 32.2238
Karpas-231 GDSC1 1.3337 11.7994 -4.8036 25.7979
ATN-1 GDSC1 1.3705 2.9416 -0.5146 1.2825
SCC-3 GDSC1 1.3854 2.4559 -0.3185 0.369
CTV-1 GDSC1 1.4062 3.7485 -0.8425 3.2466
CCRF-CEM GDSC1 1.4158 3.4249 -0.6953 2.2788
VAL GDSC1 1.5859 4.2379 -0.9587 3.6774
KY821 GDSC1 1.6234 3.2047 -0.5032 0.9381
P30/OHK GDSC1 1.6321 8.6608 -3.0308 17.0218
KMS-26 CTRP2 1.6641 3.6627 1.6495 29.2307
NALM-6 GDSC1; CTRP2 1.6696 6.057 1.2666 30.4908
HH [Human lymphoma] GDSC1 1.6711 8.9109 -3.1249 17.4227
BC-3 GDSC1 1.7915 3.5838 -0.5772 1.119
MN-60 GDSC1 1.806 4.1784 -0.8141 2.3892
VL51 GDSC1 1.8344 4.1146 -0.7728 2.1069
Hs 445 GDSC1 1.8445 3.223 -0.4179 0.426
TK [Human B-cell lymphoma] GDSC1 1.8475 3.4574 -0.5038 0.7401
H9 GDSC1 1.8484 3.7603 -0.6214 1.2744
RC-K8 GDSC1 1.977 3.2553 -0.3792 0.2533
ME1 GDSC1 1.9901 3.2604 -0.3763 0.2413
Namalwa GDSC1 2.0191 3.6544 -0.5071 0.6249
U-698-M GDSC1 2.0474 3.7779 -0.5417 0.7358
CTB-1 GDSC1 2.1124 5.1405 -1.0657 3.4335
MLMA GDSC1 2.1209 3.9386 -0.5718 0.7984
WSU-NHL GDSC1 2.2524 4.0285 -0.5517 0.6297
RPMI-8866 GDSC1 2.2731 4.0828 -0.5634 0.6578
PL-21 GDSC1 2.3082 5.399 -1.074 3.1735
SU-DHL-16 GDSC1 2.317 3.5732 -0.3673 0.1307
ROS-50 GDSC1 2.3514 4.7552 -0.788 1.552
EM-2 GDSC1; CTRP2 2.4688 5.6595 2.2402 24.6089
MEG-01 GDSC1 2.7237 4.7845 -0.6422 0.648
JVM-2 GDSC1 2.7263 5.4264 -0.8844 1.6258
MHH-PREB-1 GDSC1 2.7347 4.3521 -0.4853 0.2318
MOTN-1 CTRP2 2.745 8.4413 1.5919 26.0584
DG-75 GDSC1 2.8037 4.5016 -0.5121 0.2646
Jiyoye GDSC1 2.8708 4.5752 -0.5134 0.2471
L-1236 GDSC1 2.8892 4.7418 -0.5644 0.3508
NU-DUL-1 GDSC1; CTRP2 2.9931 6.1781 2.0324 12.6596
ALL-SIL GDSC1; CTRP2 3.1587 8.7359 1.9005 23.7886
OPM-2 GDSC1; CTRP2 3.3165 8.576 2.1326 22.5061
OCI-Ly10 CTRP2 3.428 7.3168 2.3853 15.7874
HL-60 GDSC1; CTRP2 3.686 6.7814 3.2374 17.3233
KE-37 GDSC1; CTRP2 3.6984 10.0096 1.8795 22.4004
KMS-11 GDSC1; CTRP2 3.7074 11.1992 1.3308 24.2929
EB1 CTRP2 3.7142 8.3553 2.639 19.5218
SUP-T11 CTRP2 3.9175 6.479 3.5915 15.3313
MOLT-16 GDSC1; CTRP2 3.9387 9.6618 2.2791 20.3008
RPMI-8226 GDSC1; CTRP2 4.1287 9.5622 2.5134 18.9245
BV-173 GDSC1; CTRP2 4.2562 11.2135 1.8515 21.0873
BL-70 CTRP2 4.2959 6.8567 3.866 13.2122
HD-MY-Z CTRP2 4.5146 7.7601 3.7222 13.1802
P12-Ichikawa GDSC1; CTRP2 4.5484 9.4409 2.9812 16.0532
OCI-Ly3 CTRP2 4.5648 9.1626 3.1289 15.4236
RL GDSC1; CTRP2 4.7045 7.5561 4.0065 11.5606
ST486 GDSC1; CTRP2 4.7273 10.4183 2.6819 16.8127
WSU-DLCL2 GDSC1; CTRP2 4.9579 7.6388 4.2266 10.0338
MOLP-2 CTRP2 4.9703 11.3095 2.4707 17.079
HPB-ALL CTRP2 5.0144 10.5264 2.8961 15.302
RS4;11 GDSC1; CTRP2 5.0923 13.1111 1.6893 19.7199
NU-DHL-1 CTRP2 5.1184 8.5969 3.9331 10.8385
Ku812 GDSC1; CTRP2 5.1188 10.4446 3.0322 14.5207
Mono-Mac-1 CTRP2 5.1611 49.4329 -16.3902 41.9475
KMS-21-BM CTRP2 5.5419 7.1292 5.042 5.2954
KMS-12-BM GDSC1; CTRP2 5.6294 11.8401 2.7938 14.3785
SUP-B15 GDSC1; CTRP2 5.6547 12.7571 2.358 16.0316
GA-10 CTRP2 5.6661 11.5649 2.9629 13.6253
AML-193 CTRP2 5.6688 12.0449 2.7257 14.5673
TALL-1 [Human adult T-ALL] CTRP2 5.8749 12.8829 2.4829 15.0992
JURL-MK1 GDSC1; CTRP2 5.9976 10.6147 3.7201 9.8491
LP-1 GDSC1; CTRP2 6.0444 16.2911 0.921 20.3166
NCO2 CTRP2 6.0947 10.158 4.0294 8.3695
Peer CTRP2 6.158 7.694 5.3122 2.8652
L-428 GDSC1; CTRP2 6.1784 9.4235 4.4652 6.3835
SET-2 CTRP2 6.1976 7.8929 5.2445 3.078
SIG-M5 GDSC1; CTRP2 6.2362 7.4032 5.5175 1.871
L-363 GDSC1; CTRP2 6.2375 7.7762 5.3337 2.6349
NOMO-1 GDSC1; CTRP2 6.3232 7.8198 5.377 2.3111
EJM GDSC1; CTRP2 6.3555 10.7585 3.9413 8.2512
DEL GDSC1; CTRP2 6.4003 9.0359 4.8339 4.4412
Granta-519 GDSC1; CTRP2 6.4747 8.9797 4.9182 3.9655
RPMI-8402 GDSC1; CTRP2 6.5938 9.4639 4.7681 4.3931
SU-DHL-1 GDSC1; CTRP2 6.5968 7.7925 5.5766 1.121
TF-1 CTRP2 6.6527 8.1941 5.4244 1.6392
SR GDSC1; CTRP2 6.6651 8.2096 5.425 1.621
P31/FUJ GDSC1; CTRP2 6.7218 8.7561 5.203 2.4229
OCI-M1 GDSC1; CTRP2 6.7227 8.4047 5.3703 1.7605
MM1.S CTRP2 6.7656 8.4527 5.3751 1.6878
F-36P CTRP2 6.827 10.8293 4.2687 6.0806
PL21 CTRP2 6.9025 9.1481 5.1362 2.4443
U-937 CTRP2 6.9576 11.0065 4.2771 5.8386
RCH-ACV CTRP2 7.0536 14.6416 2.5552 12.6091
Karpas-620 GDSC1; CTRP2 7.0859 9.7863 4.954 2.9199
OCI-Ly19 GDSC1; CTRP2 7.1143 11.5142 4.1418 6.1493
MC116 GDSC1; CTRP2 7.1317 8.3311 5.63 0.4651
THP-1 GDSC1; CTRP2 7.1424 9.2993 5.2154 1.849
HT GDSC1; CTRP2 7.1538 8.7952 5.4465 1.016
JJN-3 GDSC1; CTRP2 7.1973 9.4933 5.1597 1.9946
Ci-1 CTRP2 7.2194 8.2642 5.6951 0.257
KE-97 CTRP2 7.2288 11.7724 4.0974 6.1558
Pfeiffer CTRP2 7.2316 18.6289 0.7121 18.735
MOLM-6 CTRP2 7.2612 14.6736 2.6971 11.7064
Hs 611.T CTRP2 7.2662 9.7726 5.0734 2.239
CMK CTRP2 7.3045 9.8007 5.0835 2.1574
PF-382 GDSC1; CTRP2 7.3948 9.4635 5.2858 1.3407
NCI-H929 CTRP2 7.4079 11.0941 4.5454 4.1032
HEL 92.1.7 CTRP2 7.4577 8.7067 5.6272 0.3027
SU-DHL-4 GDSC1; CTRP2 7.4725 10.1077 5.0434 2.1208
ME1 CTRP2 7.4733 9.2783 5.4058 0.8854
JVM-3 GDSC1; CTRP2 7.4761 12.5307 3.903 6.5724
MOLP-8 GDSC1; CTRP2 7.5136 13.0224 3.6911 7.3671
L-540 GDSC1; CTRP2 7.5148 12.8422 3.7792 7.012
NB4 GDSC1; CTRP2 7.555 8.6 5.7049 0.1296
P3HR-1 CTRP2 7.5564 9.2672 5.4508 0.6952
OCI-AML-2 GDSC1; CTRP2 7.5567 8.7369 5.6562 0.2081
SU-DHL-10 GDSC1; CTRP2 7.6135 8.7171 5.6853 0.144
U266B1 GDSC1; CTRP2 7.6289 9.354 5.4496 0.6528
Mino CTRP2 7.6618 10.0305 5.1831 1.4463
SKM-1 CTRP2 7.6707 8.7862 5.6823 0.1347
OCI-AML-5 GDSC1; CTRP2 7.6765 8.7465 5.6984 0.1117
M-07e CTRP2 7.7174 9.4935 5.4346 0.6401
KO52 CTRP2 7.752 9.1903 5.567 0.3098
EHEB CTRP2 7.7597 9.4984 5.4519 0.5713
JeKo-1 CTRP2 7.7983 9.2269 5.5722 0.2824
Raji GDSC1; CTRP2 7.8077 9.1248 5.6133 0.2054
KMS-27 CTRP2 7.8162 16.4657 2.2265 12.5684
DB GDSC1; CTRP2 7.8334 11.5353 4.6078 3.3333
DND-41 GDSC1; CTRP2 7.8346 13.1083 3.8699 6.1929
AMO1 GDSC1; CTRP2 7.853 8.9569 5.6893 0.0902
SU-DHL-8 GDSC1; CTRP2 7.8543 9.2773 5.576 0.2561
HEL GDSC1; CTRP2 7.8736 9.0753 5.6557 0.1263
Reh GDSC1; CTRP2 7.9081 9.0696 5.6703 0.1022
LAMA-84 GDSC1; CTRP2 7.9144 10.4792 5.1232 1.4275
MOLM-16 CTRP2 7.9283 9.7759 5.418 0.5664
Karpas-422 GDSC1; CTRP2 7.9595 10.1981 5.2633 0.9642
RPMI-6666 GDSC1; CTRP2 7.9863 9.7298 5.4608 0.4386
SUP-HD1 GDSC1; CTRP2 8.0064 15.9997 2.592 10.9072
Jurkat CTRP2 8.0383 9.8101 5.4521 0.4352
REC-1 CTRP2 8.0548 14.9446 3.1379 8.7471
SK-MM-2 GDSC1; CTRP2 8.0662 17.198 2.0496 12.8126
A4/Fukuda GDSC1; CTRP2 8.1036 9.553 5.5728 0.1896
KHM-1B CTRP2 8.107 9.6888 5.5252 0.2658
Kasumi-2 CTRP2 8.1603 9.5197 5.6055 0.1326
OCI-AML-3 GDSC1; CTRP2 8.2207 9.3202 5.6943 0.0428
GDM-1 GDSC1; CTRP2 8.2806 10.8505 5.1503 1.074
K-562 GDSC1; CTRP2 8.282 9.7114 5.5831 0.1368
HDLM-2 GDSC1; CTRP2 8.2972 10.1803 5.42 0.3979
Ri-1 CTRP2 8.3179 15.5867 3.0092 8.8615
MOLT-13 GDSC1; CTRP2 8.3544 9.8534 5.56 0.1513
KCL-22 GDSC1; CTRP2 8.4278 9.9414 5.5562 0.142
SU-DHL-6 GDSC1; CTRP2 8.4405 10.1818 5.476 0.2507
MHH-CALL-4 CTRP2 8.5458 10.35 5.4559 0.254
Ki-JK CTRP2 8.6473 10.1794 5.5528 0.1098
Karpas-299 GDSC1; CTRP2 8.685 10.0341 5.6147 0.0551
SUP-T1 GDSC1; CTRP2 8.8909 10.5153 5.5241 0.1037
MHH-CALL-3 CTRP2 9.0776 11.0986 5.39 0.2224
KM-H2 GDSC1; CTRP2 10.0914 17.8881 3.0587 6.4474
⏷ Show the Full List of 204 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.2661 7.3431 4.6704 7.477
TE15 CTRP2 7.2284 13.2254 3.3865 9.036
TE-15 GDSC1 1.4902 3.762 -0.8018 2.8266
KYSE-270 GDSC1 1.9144 4.4789 -0.8859 2.6532
OE33 GDSC1 2.1225 6.4056 -1.6251 7.0407
T.T GDSC1 2.5029 4.1612 -0.5031 0.3516
TE-8 GDSC1 3.3575 5.273 -0.5796 0.2382
KYSE-140 GDSC1; CTRP2 5.6938 13.2153 2.1627 16.6928
OE21 GDSC1; CTRP2 5.7176 11.5011 3.0391 13.2113
TE-5 GDSC1; CTRP2 5.783 9.1459 4.2708 7.9749
TE-4 GDSC1; CTRP2 6.0302 8.7756 4.6669 5.8173
KYSE-410 GDSC1; CTRP2 6.8951 13.3946 3.052 10.9368
TE-6 GDSC1; CTRP2 7.0825 12.922 3.4278 9.108
EC-GI-10 GDSC1; CTRP2 7.407 9.0328 5.4751 0.7255
KYSE-30 CTRP2 7.4162 12.4677 3.8917 6.7065
TE-9 GDSC1; CTRP2 7.6478 9.0305 5.5841 0.3158
TE-10 GDSC1; CTRP2 7.6659 9.9681 5.2122 1.3466
OE19 GDSC1; CTRP2 7.6772 9.0434 5.5913 0.2893
COLO 680N GDSC1; CTRP2 7.922 9.2413 5.6152 0.1717
KYSE-70 GDSC1; CTRP2 8.0977 9.9184 5.4359 0.4449
KYSE-450 GDSC1; CTRP2 8.1094 9.3136 5.6582 0.0834
TE-1 GDSC1; CTRP2 8.2172 10.3413 5.3246 0.6468
TE-11 GDSC1; CTRP2 8.6404 10.5999 5.4023 0.3149
KYSE-520 GDSC1; CTRP2 8.8651 10.9136 5.3758 0.2944
TE-14 CTRP2 8.9892 10.739 5.4826 0.1298
KYSE-180 GDSC1; CTRP2 9.6473 16.588 3.3865 5.7787
KYSE-510 GDSC1; CTRP2 10.0281 18.0246 2.9587 6.8685
KYSE-150 GDSC1; CTRP2 10.872 20.5487 2.3113 8.1359
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.1923 9.4571 5.6385 0.0908
MZ-PC-1 GDSC1 1.6817 4.0399 -0.8195 2.616
Capan-1 GDSC1 1.8593 3.7039 -0.5941 1.1303
PL4 GDSC1 2.6014 4.1646 -0.4685 0.2378
MIA PaCa-2 GDSC1; CTRP2 5.3079 9.2956 3.7705 11.0768
Panc 04.03 GDSC1; CTRP2 6.229 13.9818 2.2284 15.3723
PaTu 8988s CTRP2 6.5961 8.1634 5.4019 1.8032
Panc 10.05 GDSC1; CTRP2 6.6743 12.785 3.1836 10.796
SNU-410 CTRP2 6.8975 11.1539 4.161 6.4108
Panc 08.13 GDSC1; CTRP2 7.16 11.8559 4.0078 6.6252
PSN1 GDSC1; CTRP2 7.3291 11.3754 4.3586 4.9547
PK-59 CTRP2 7.352 10.8323 4.6328 3.8328
TCC-Pan2 CTRP2 7.3525 9.9914 5.0251 2.3209
HPAC GDSC1; CTRP2 7.359 9.6917 5.1648 1.8003
PaTu 8902 GDSC1; CTRP2 7.4404 11.4704 4.3881 4.6821
SU.86.86 GDSC1; CTRP2 7.457 9.4042 5.3444 1.0918
KP-3 GDSC1; CTRP2 7.4666 12.0837 4.112 5.7474
HuP-T3 GDSC1; CTRP2 7.4905 16.2865 2.0729 13.6681
Capan-2 GDSC1; CTRP2 7.5629 10.5046 4.9167 2.4876
SNU-213 CTRP2 7.7156 9.0581 5.6014 0.2559
YAPC GDSC1; CTRP2 7.744 8.996 5.6352 0.1876
DAN-G GDSC1; CTRP2 7.7516 14.8279 2.9813 9.8113
Panc 03.27 GDSC1; CTRP2 7.808 9.4569 5.4893 0.4553
PaTu 8988t GDSC1; CTRP2 7.8124 9.5174 5.4678 0.5042
Panc 05.04 CTRP2 7.833 9.5967 5.4459 0.5471
HuP-T4 GDSC1; CTRP2 7.9027 10.5213 5.0992 1.5152
L3.3 CTRP2 7.9828 9.3516 5.5988 0.1809
KP-2 GDSC1; CTRP2 8.0829 9.5082 5.5809 0.1827
Hs 766T GDSC1; CTRP2 8.1006 9.7074 5.5158 0.2844
QGP-1 GDSC1; CTRP2 8.1373 9.5246 5.5954 0.1501
PK-45H CTRP2 8.1617 9.9192 5.4621 0.3648
SUIT-2 GDSC1; CTRP2 8.1993 9.627 5.5823 0.1543
KP-4 GDSC1; CTRP2 8.2868 10.5978 5.2548 0.7852
SW1990 GDSC1; CTRP2 8.2882 13.3172 4.0644 4.8499
Panc 02.03 GDSC1; CTRP2 8.3653 10.3267 5.3931 0.4261
HPAF-II GDSC1; CTRP2 8.4791 10.3375 5.4347 0.3082
AsPC-1 GDSC1; CTRP2 8.6591 16.0401 3.0217 8.339
BxPC-3 GDSC1; CTRP2 8.7405 16.6306 2.7945 9.0769
CFPAC-1 GDSC1; CTRP2 8.8363 10.4411 5.5302 0.1053
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.1621 22.3609 -0.4232 20.4248
MZ-MEL-2 GDSC1 0.3811 3.7019 -1.5192 10.9761
MMAc-SF GDSC1 0.6533 3.1016 -1.0192 6.3101
CP66-MEL GDSC1 1.3242 3.6901 -0.8635 3.5478
COLO 679 GDSC1 1.5624 4.1746 -0.9438 3.6232
LB373-MEL-D GDSC1 1.571 2.7641 -0.3579 0.3891
SH-4 GDSC1 1.591 6.0116 -1.7779 9.3223
CP50-MEL-B GDSC1 1.5977 3.2159 -0.5191 1.0406
VMRC-MELG GDSC1 1.6517 3.0911 -0.4471 0.6657
WM1552C GDSC1 1.6634 4.0961 -0.8535 2.8579
MZ-MEL-7 GDSC1 1.6722 4.11 -0.8548 2.8513
A-431 GDSC1 1.7007 4.283 -0.9148 3.1822
G-mel GDSC1 1.7082 3.7955 -0.7025 1.8809
HMV-II GDSC1 1.7548 5.9432 -1.639 7.966
COLO 783 GDSC1 1.8399 3.3047 -0.4497 0.5375
GAK GDSC1 1.8929 3.4231 -0.4722 0.5835
LB2518-MEL GDSC1 1.8955 3.3219 -0.4339 0.4486
Hs 938.T GDSC1 1.9976 3.5128 -0.4635 0.4861
SK-MEL-24 GDSC1 2.0416 3.4948 -0.4399 0.388
CHL-1 GDSC1 2.0423 4.1292 -0.6798 1.3527
IST-MEL1 GDSC1 2.0456 4.779 -0.9458 2.8108
WM35 GDSC1 2.0949 4.0004 -0.6062 0.9628
M14 GDSC1 2.2335 3.8275 -0.4859 0.4272
451Lu GDSC1 2.2626 3.8395 -0.4792 0.3934
WM278 GDSC1 2.2914 4.2963 -0.6359 0.9226
A-388 GDSC1 2.5736 4.3205 -0.533 0.3993
DJM-1 GDSC1 2.7222 4.3414 -0.4861 0.2369
COLO 741 CTRP2 4.1495 6.7811 3.737 14.1156
WM88 CTRP2 5.0466 7.5492 4.3565 9.2892
Hs 895.T CTRP2 5.4036 12.6552 2.1909 17.1976
WM115 GDSC1; CTRP2 5.5861 7.0023 5.1451 4.7687
Hs 944.T CTRP2 6.0743 13.9669 2.108 16.1278
Hs 294T CTRP2 6.8363 7.9527 5.6414 0.6465
IGR-37 GDSC1; CTRP2 6.8558 8.3529 5.4757 1.2049
WT2-iPS GDSC1; CTRP2 6.8994 10.6589 4.4051 5.4042
MeWo GDSC1; CTRP2 6.9016 11.935 3.7794 7.9736
Hs 940.T GDSC1; CTRP2 7.0183 11.6 4.0305 6.7538
Hs 688(A).T CTRP2 7.0241 10.6657 4.4905 4.8648
WM1799 CTRP2 7.0906 9.1417 5.2564 1.755
HT-144 GDSC1; CTRP2 7.172 11.7675 4.0594 6.3962
SK-MEL-31 CTRP2 7.1839 8.8204 5.4516 0.9725
SK-MEL-1 GDSC1; CTRP2 7.2085 8.6333 5.5432 0.6638
IGR-1 GDSC1; CTRP2 7.2751 13.5317 3.2703 9.4262
UACC-62 GDSC1; CTRP2 7.3651 10.9508 4.5853 4.0027
UACC-257 GDSC1; CTRP2 7.3701 10.4932 4.8039 3.1419
SK-MEL-28 GDSC1; CTRP2 7.3884 8.1622 5.7964 0.0511
CJM [Human melanoma] CTRP2 7.4434 8.4502 5.7161 0.1408
HMCB CTRP2 7.4833 8.56 5.6919 0.1688
K029AX CTRP2 7.5368 15.2962 2.5957 11.6388
Hs 852.T CTRP2 7.6247 9.4882 5.3932 0.8149
A2058 GDSC1; CTRP2 7.6327 8.5512 5.75 0.0617
SK-MEL-30 GDSC1; CTRP2 7.6471 8.7263 5.6946 0.1229
SK-MEL-2 GDSC1; CTRP2 7.6782 8.9035 5.6431 0.1933
RPMI-7951 GDSC1; CTRP2 7.7026 11.9544 4.3307 4.5588
WM266-4 CTRP2 7.7211 11.5501 4.5318 3.756
WM793 GDSC1; CTRP2 7.7282 9.0608 5.6054 0.2441
G-361 GDSC1; CTRP2 7.7352 10.8564 4.8587 2.5129
MDA-MB-435S CTRP2 7.8272 9.1786 5.6014 0.2198
Mel Ho GDSC1; CTRP2 7.8724 9.5001 5.5001 0.4017
A101D GDSC1; CTRP2 7.8848 9.239 5.6018 0.2022
Hs 936.T CTRP2 7.9166 8.8683 5.7413 0.038
IPC-298 GDSC1; CTRP2 8.0371 9.2661 5.6488 0.1042
A-375 GDSC1; CTRP2 8.0514 9.5115 5.5678 0.2109
SK-MEL-5 GDSC1; CTRP2 8.0601 9.336 5.633 0.1184
WM983B CTRP2 8.087 15.8283 2.7325 10.2535
Mel JuSo GDSC1; CTRP2 8.108 9.8982 5.4479 0.4149
SK-MEL-3 GDSC1; CTRP2 8.1445 9.5278 5.5969 0.1467
LOX-IMVI GDSC1; CTRP2 8.2866 10.0755 5.4545 0.3348
IGR-39 CTRP2 8.3255 9.5812 5.643 0.0697
COLO 800 GDSC1; CTRP2 8.7921 10.2518 5.5786 0.0702
COLO 792 GDSC1; CTRP2 9.0315 22.7683 0.0224 17.8195
RVH-421 GDSC1; CTRP2 9.8918 19.7584 2.0674 10.1401
Hs 839.T CTRP2 10.4866 28.6812 -1.8194 20.3733
COLO 829 GDSC1; CTRP2 11.0615 23.1402 1.2284 11.4147
EquiPSC Line K2 GDSC1 1.6718 4.6683 -1.1022 4.4705
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACM5.1 C GDSC1 -1.2438 1.5735 -1.9526 20.9254
KYAE-1 GDSC1 -0.2765 4.732 -2.5784 20.7979
FLO-1 GDSC1 1.8711 4.7934 -1.0451 3.7169
ESO-51 GDSC1 2.2795 4.0754 -0.5581 0.6349
KYSE-220 GDSC1 2.3841 4.7366 -0.7659 1.4125
ESO-26 GDSC1 2.4592 4.5288 -0.6539 0.8643
KYSE-50 GDSC1 2.5786 4.5615 -0.6178 0.6534
HCE-4 GDSC1 2.7903 4.5597 -0.537 0.3232
SK-GT-4 GDSC1 3.2685 5.7953 -0.7969 0.8376
OACP4 C GDSC1 3.7148 5.5737 -0.5576 0.1356
TE-12 GDSC1 4.176 6.5045 -0.7109 0.2632
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 5.8627 11.6933 3.0671 12.8036
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-17 GDSC1 0.1573 4.4346 -2.0643 15.7377
LA-N-6 GDSC1 0.5045 5.1767 -2.1564 15.1563
NH-12 GDSC1 0.9458 2.7071 -0.6407 2.7875
SJNB-13 GDSC1 1.098 2.8609 -0.6219 2.3619
SJNB-7 GDSC1 1.1031 4.0867 -1.1854 6.3453
IMR-5 GDSC1 1.16 7.5856 -2.8493 17.3965
SJNB-6 GDSC1 1.206 2.9218 -0.5896 1.9648
CHP-134 GDSC1 1.2627 3.5892 -0.8539 3.6063
SJNB-5 GDSC1 1.3342 4.4788 -1.2207 6.0334
SK-N-AS GDSC1 1.3554 5.337 -1.6134 8.7845
NB(TU)1 GDSC1 1.5534 3.1143 -0.4989 0.9891
SK-N-MC-IXC GDSC1 1.571 2.5408 -0.2785 0.1671
CHP-212 GDSC1 1.6258 3.3661 -0.5662 1.2454
NB69 GDSC1 1.6469 4.8263 -1.1886 5.1089
KP-N-YS GDSC1 1.6739 8.719 -3.0291 16.8938
SJNB-12 GDSC1 1.7362 9.2502 -3.2438 17.8685
SJNB-10 GDSC1 1.7709 3.4543 -0.5355 0.9443
SiMa GDSC1 1.9077 5.1255 -1.1716 4.472
SK-N-BE(2)-M17 GDSC1 2.1759 3.7868 -0.4935 0.4809
TGW GDSC1 2.2244 3.7607 -0.4655 0.3731
GOTO GDSC1 2.4867 4.4327 -0.607 0.6734
SJNB-14 GDSC1 2.5241 4.1628 -0.4959 0.3251
SK-N-BE(2) CTRP2 2.6797 6.821 2.1344 24.3374
GI-ME-N GDSC1 3.1451 11.2811 -3.256 14.3608
SK-N-DZ GDSC1; CTRP2 5.9593 7.1741 5.4072 2.8473
MHH-NB-11 GDSC1; CTRP2 6.7119 11.076 4.0609 7.1295
NB1 GDSC1; CTRP2 6.8939 8.5035 5.4299 1.3312
Kelly GDSC1; CTRP2 7.0424 8.7841 5.3897 1.3199
SK-N-FI GDSC1; CTRP2 7.8028 16.0495 2.4208 11.8694
KP-N-SI9s CTRP2 7.8434 10.6569 5.0087 1.872
CHP-126 GDSC1; CTRP2 7.8904 9.3927 5.5478 0.2964
KP-N-YN GDSC1; CTRP2 8.2474 12.6545 4.3448 3.8428
NH-6 CTRP2 8.3382 18.7625 1.4809 14.3694
SK-N-SH GDSC1; CTRP2 8.808 10.5528 5.4819 0.1605
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 7.0702 11.4791 4.1273 6.2764
HuH-28 CTRP2 7.4908 8.834 5.5926 0.3653
SNU-1079 CTRP2 7.8502 15.9633 2.4975 11.5065
HuCC-T1 GDSC1; CTRP2 7.8716 10.7716 4.9738 1.9655
SNU-308 CTRP2 8.0599 9.5855 5.5443 0.2471
SNU-245 CTRP2 8.2408 11.462 4.8729 1.9702
SNU-1196 CTRP2 8.3025 9.8016 5.5591 0.1631
SNU-869 CTRP2 8.4495 14.2157 3.747 5.8587
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1 -0.7539 22.7212 -11.9725 42.6244
BT-483 GDSC1 0.9034 2.8118 -0.7144 3.3988
OCUB-M GDSC1 0.964 3.959 -1.2178 6.9468
MDA-MB-175-VII GDSC1 1.1714 5.5305 -1.8335 10.8397
YMB-1-E GDSC1 1.1845 3.1944 -0.7215 2.8612
MDA-MB-330 GDSC1 1.3202 5.2094 -1.576 8.611
Evsa-T GDSC1 1.3736 2.9319 -0.5091 1.249
HCC1569 GDSC1 1.3761 9.3036 -3.5352 20.3844
EFM-19 GDSC1 1.3787 5.7365 -1.7892 9.9567
HCC1599 GDSC1 1.4688 3.3881 -0.6519 1.9314
UACC-893 GDSC1 1.6611 5.3477 -1.4201 6.6755
MRK-nu-1 GDSC1 1.776 3.1431 -0.4157 0.4595
HCC1187 GDSC1 1.7985 3.9715 -0.731 1.9187
HCC70 GDSC1 1.9597 3.9584 -0.6495 1.2927
MFM-223 GDSC1 2.2991 3.7315 -0.4277 0.2487
MDA-MB-415 GDSC1 2.3467 3.8666 -0.4574 0.3003
COLO 824 GDSC1 2.5164 4.7561 -0.716 1.0693
MDA-MB-436 GDSC1 2.5389 4.1248 -0.4772 0.2765
UACC-812 GDSC1 2.5714 4.3447 -0.5424 0.4258
Hs 578Bst CTRP2 2.6093 3.4631 2.6092 49.158
MDA-MB-157 GDSC1; CTRP2 3.9002 8.479 2.7763 18.4986
KPL-1 CTRP2 4.8132 5.9303 3.6774 0.9908
AU565 GDSC1; CTRP2 6.023 11.1647 3.4664 10.8519
CAL-120 GDSC1; CTRP2 6.3119 8.9122 4.8269 4.624
MCF-7 GDSC1; CTRP2 6.4774 9.4321 4.6965 4.8827
DU4475 GDSC1; CTRP2 6.5006 14.27 2.3053 14.5631
CAL-85-1 GDSC1; CTRP2 6.8117 9.1136 5.0926 2.7397
T-47D GDSC1; CTRP2 6.8156 14.6979 2.3423 13.8431
BT-20 GDSC1; CTRP2 6.9005 9.2578 5.0829 2.6572
CAMA-1 GDSC1; CTRP2 7.1133 15.3341 2.2575 13.6336
HMC-1-8 CTRP2 7.1855 9.8478 4.9887 2.6578
CAL-51 GDSC1; CTRP2 7.3182 9.3611 5.2887 1.4024
HDQ-P1 GDSC1; CTRP2 7.3183 9.581 5.191 1.7483
HCC38 GDSC1; CTRP2 7.4736 9.4143 5.3487 1.0645
HCC202 CTRP2 7.8297 10.3576 5.1311 1.473
MDA-MB-453 GDSC1; CTRP2 7.8566 12.2959 4.269 4.6006
HCC1428 GDSC1; CTRP2 7.8592 13.2332 3.8267 6.3291
CAL-148 GDSC1; CTRP2 7.8859 8.9713 5.6961 0.0782
HCC1143 CTRP2 7.9871 12.8639 4.0858 5.144
HCC1419 GDSC1; CTRP2 7.9998 9.4553 5.5682 0.2247
MDA-MB-361 GDSC1; CTRP2 8.0246 10.076 5.3429 0.7044
HCC1954 GDSC1; CTRP2 8.0344 14.1314 3.515 7.3084
Hs 578T GDSC1; CTRP2 8.0606 9.976 5.3981 0.5481
MDA-MB-231 GDSC1; CTRP2 8.1724 10.1975 5.3609 0.5817
BT-474 GDSC1; CTRP2 8.2218 9.3404 5.688 0.0468
HCC1806 GDSC1; CTRP2 8.2247 10.2332 5.3697 0.5363
ZR-75-1 CTRP2 8.2268 9.6193 5.5951 0.1328
EFM-192A GDSC1; CTRP2 8.4402 10.3993 5.3965 0.3912
BT-549 GDSC1; CTRP2 8.4632 17.2586 2.3028 11.2864
HCC1937 GDSC1; CTRP2 8.4928 14.6317 3.5794 6.4427
JIMT-1 GDSC1; CTRP2 8.5497 9.9579 5.5937 0.0848
HCC1395 GDSC1; CTRP2 8.5501 10.2969 5.4765 0.2219
HCC2218 GDSC1; CTRP2 8.8253 10.6443 5.4563 0.1884
ZR-75-30 GDSC1; CTRP2 9.0095 19.1807 1.753 12.4265
HCC1500 GDSC1; CTRP2 9.277 18.0364 2.4811 9.4947
MDA-MB-468 GDSC1; CTRP2 9.6533 19.2819 2.1376 10.2087
BT 428 CTRP2 3.6259 6.3541 3.3144 17.2145
BT147 CTRP2 3.6317 9.7801 1.9187 22.4344
BT 131 CTRP2 3.8011 7.3892 3.1321 17.3957
BT 440 CTRP2 4.0326 8.3494 2.969 17.4019
BT 482 CTRP2 4.1194 6.2567 3.882 13.6638
BT 330 CTRP2 4.2938 7.4933 3.6085 14.2107
BT 271 CTRP2 4.4305 6.6915 4.072 12.0495
BT 216 CTRP2 4.505 10.3042 2.5265 17.9468
BT 504 CTRP2 4.6678 10.7254 2.4767 17.7529
BT 248 CTRP2 4.7065 8.4964 3.5806 13.2613
BT 416 CTRP2 4.7484 10.2951 2.7615 16.4492
BT 145 CTRP2 4.8652 8.0525 3.944 11.4031
BT 286 CTRP2 5.3015 8.3 4.2503 9.1089
BT 245 CTRP2 5.31 15.2868 0.7977 22.2365
BT 444 CTRP2 5.3557 10.5862 3.1768 13.4138
BT 232 CTRP2 5.4928 9.8262 3.6762 11.064
BT 422 CTRP2 5.8961 8.5966 4.6427 6.1842
BT 333 CTRP2 5.9459 12.2632 2.8526 13.5007
BT 498 CTRP2 5.9782 9.3947 4.3138 7.4025
BT 328 CTRP2 6.0492 11.3773 3.382 11.1488
BT 172 CTRP2 6.1372 9.1579 4.5643 6.0445
BT 359 CTRP2 6.2831 11.058 3.7336 9.2491
BT 112 CTRP2 7.0283 9.2081 5.188 2.0849
BT164 CTRP2 7.1292 9.2285 5.2398 1.7734
BT 340 CTRP2 7.1365 13.3666 3.2488 9.7395
BT 187 CTRP2 7.6885 10.3799 5.0449 1.8942
BT 231 CTRP2 7.7036 11.924 4.3456 4.4992
BT 239 CTRP2 7.7695 9.0907 5.6107 0.2212
BT 224 CTRP2 7.8329 9.3414 5.5436 0.3261
BT 228 CTRP2 7.9696 9.3224 5.6043 0.176
BT 159 CTRP2 8.0247 9.2338 5.6555 0.099
BT 139 CTRP2 8.0305 9.1613 5.6823 0.0715
BT 320 CTRP2 8.645 19.4621 1.36 14.298
BT 179 CTRP2 9.21 19.887 1.5507 12.8227
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 8.0926 9.2572 5.6715 0.0733
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 0.1412 4.6881 -2.2042 16.7603
LN-405 GDSC1 1.2482 3.5062 -0.8248 3.4362
KNS-42 GDSC1 1.3156 4.6889 -1.3315 6.8728
YKG-1 GDSC1 1.3306 2.8316 -0.4887 1.1927
D-392MG GDSC1 1.3955 6.4293 -2.1121 12.1101
D-336MG GDSC1 1.5044 3.9693 -0.8853 3.3451
KNS-81-FD GDSC1 1.6651 4.4431 -1.0052 3.8353
D-566MG GDSC1 1.8106 3.6821 -0.6075 1.2468
D-542MG GDSC1 1.8333 3.4173 -0.4946 0.7138
SK-MG-1 GDSC1 1.8762 4.0537 -0.7271 1.7938
GI-1 GDSC1 1.9018 3.8935 -0.6501 1.3585
D-263MG GDSC1 1.9304 3.3187 -0.4193 0.3835
LNZTA3WT4 GDSC1 1.9356 3.7901 -0.594 1.0543
D-502MG GDSC1 1.9915 4.0052 -0.6536 1.2793
MOG-G-CCM GDSC1 1.9926 4.5478 -0.8751 2.4723
PFSK-1 GDSC1 2.1173 3.925 -0.5681 0.7867
Onda 10 GDSC1 2.3663 4.2483 -0.5872 0.6811
MOG-G-UVW GDSC1 2.4076 4.0041 -0.4831 0.34
D-423MG GDSC1 2.4704 5.0127 -0.8362 1.6605
H4 GDSC1 2.5002 4.5148 -0.6319 0.7529
KS-1 [Human Krukenberg tumour] GDSC1 2.5423 5.0961 -0.8367 1.5872
KINGS-1 GDSC1 2.5594 4.9465 -0.7707 1.2668
Onda 11 GDSC1 2.611 4.8042 -0.6947 0.9098
M059J GDSC1 2.6202 4.413 -0.5483 0.4198
SF268 GDSC1; CTRP2 4.3886 6.8004 3.9865 12.4926
CAS-1 GDSC1; CTRP2 4.5809 6.3367 3.3428 2.8594
SNU-626 CTRP2 4.6163 8.4502 3.5128 13.757
Daoy GDSC1; CTRP2 4.9518 9.4793 3.3489 13.6156
SF539 GDSC1; CTRP2 4.991 8.7985 3.7144 12.0328
SNU-489 CTRP2 5.0709 10.0918 3.1615 14.1052
SF126 GDSC1; CTRP2 5.1988 6.2297 5.0651 6.1104
KNS-81 CTRP2 5.2269 7.1036 4.7401 7.2958
SNB-75 GDSC1; CTRP2 5.3695 8.5946 4.1709 9.2818
KALS-1 GDSC1; CTRP2 5.4878 9.3958 3.8849 10.2086
GB-1 GDSC1; CTRP2 5.8863 8.7111 4.5771 6.4796
D283 Med GDSC1; CTRP2 6.0581 8.807 4.6745 5.7317
SW1088 GDSC1; CTRP2 6.1839 11.468 3.448 10.6179
NMC-G1 GDSC1; CTRP2 6.2955 7.9478 5.293 2.7057
AM-38 GDSC1; CTRP2 6.6049 11.3126 3.8616 8.1388
SNU-1105 CTRP2 6.6426 14.0299 2.5386 13.4065
SNU-466 CTRP2 7.1969 8.8673 5.4383 1.0054
U-251MG GDSC1; CTRP2 7.4645 10.9668 4.6422 3.6502
M059K CTRP2 7.5515 8.8602 5.6083 0.304
KG-1-C CTRP2 7.5555 8.8026 5.6315 0.2551
SNU-201 CTRP2 7.5632 8.798 5.6363 0.2429
SW1783 GDSC1; CTRP2 7.6266 11.4282 4.5291 3.8836
KNS-60 CTRP2 7.6643 9.9648 5.2128 1.3461
SNU-738 CTRP2 7.7287 9.559 5.4136 0.69
ONS-76 GDSC1; CTRP2 7.7308 11.1054 4.7429 2.945
DBTRG-05MG GDSC1; CTRP2 7.7673 12.1069 4.3005 4.5925
GMS-10 CTRP2 7.8339 9.081 5.639 0.1582
LN-18 GDSC1; CTRP2 7.8345 8.8137 5.7315 0.053
TM-31 CTRP2 7.8814 8.9996 5.6848 0.0905
Becker GDSC1; CTRP2 7.9199 10.387 5.1651 1.2898
GaMG GDSC1; CTRP2 8.2357 9.6913 5.5732 0.1586
U-118MG GDSC1; CTRP2 8.2447 18.6609 1.4627 14.5787
GOS-3 CTRP2 8.4055 10.0231 5.5193 0.1946
A-172 GDSC1; CTRP2 8.4353 10.0929 5.5058 0.207
LN-229 GDSC1; CTRP2 8.616 10.3095 5.4966 0.1794
8-MG-BA GDSC1; CTRP2 8.6476 15.4841 3.2777 7.388
Hs 683 GDSC1; CTRP2 8.6758 15.6485 3.2184 7.575
U-87MG ATCC GDSC1; CTRP2 8.8443 15.4314 3.4286 6.5675
SF295 GDSC1; CTRP2 9.1335 16.8449 2.9504 7.9773
T98G GDSC1; CTRP2 10.4589 17.7275 3.3423 5.0891
42-MG-BA GDSC1; CTRP2 11.3064 22.4467 1.7033 9.6282
YH-13 GDSC1; CTRP2 11.5707 23.0827 1.5717 9.7444
CCF-STTG1 CTRP2 12.0125 23.6092 1.5964 9.1816
DK-MG GDSC1; CTRP2 13.041 27.1417 0.5992 11.0256
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 0.7834 5.1083 -1.9088 12.5282
TGBC1TKB GDSC1 2.3985 3.8402 -0.4295 0.2204
ETK-1 GDSC1 2.9827 5.1644 -0.6792 0.6211
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 3.4845 5.7595 -0.7018 0.454
MFE-296 GDSC1; CTRP2 5.2397 9.3976 3.6576 11.6953
ESS-1 GDSC1; CTRP2 5.8244 12.3974 2.6828 14.4188
KLE GDSC1; CTRP2 6.2769 8.2298 5.1389 3.3802
JHUEM-3 CTRP2 6.7697 8.7629 5.2316 2.2439
EN GDSC1; CTRP2 6.8128 10.9896 4.1793 6.4723
JHUEM-1 CTRP2 6.976 13.1282 3.2457 10.0211
MFE-319 GDSC1; CTRP2 7.1366 8.9117 5.3861 1.2386
HEC-6 CTRP2 7.157 9.5499 5.1092 2.2311
RL95-2 GDSC1; CTRP2 7.3879 12.7848 3.7176 7.4508
HEC-1-A CTRP2 7.4818 11.4407 4.4296 4.4618
HEC-251 CTRP2 7.6854 9.05 5.5922 0.2846
HEC-108 CTRP2 7.6945 16.9475 1.8995 13.9535
HEC-265 CTRP2 7.7406 8.9884 5.6366 0.1862
JHUEM-7 CTRP2 7.8016 9.2143 5.5782 0.2698
EFE-184 CTRP2 7.8067 11.4598 4.6264 3.2944
AN3-CA GDSC1; CTRP2 7.9411 9.6298 5.4798 0.4166
HEC-151 CTRP2 8.2252 9.7471 5.5496 0.1939
JHUEM-2 CTRP2 8.4882 12.2179 4.6777 2.4048
HEC-59 CTRP2 8.5149 9.9757 5.5755 0.1065
HEC-1-B CTRP2 8.5533 15.4338 3.2399 7.6566
HEC-50B CTRP2 8.6548 10.3597 5.4932 0.1758
Ishikawa (Heraklio) 02 ER- CTRP2 7.4976 8.504 5.7174 0.1252
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RXF 393L GDSC1 1.1076 5.02 -1.6307 9.5795
KTCTL-21 GDSC1 1.3884 4.5933 -1.2398 6.042
A-498 GDSC1 1.5842 3.4114 -0.6043 1.4984
KTCTL-1M GDSC1 1.6594 4.3932 -0.9862 3.7209
CAL-54 GDSC1 1.7064 5.1298 -1.2917 5.6886
KTCTL-26A GDSC1 1.8152 3.7586 -0.636 1.3852
SN12C GDSC1 2.3568 4.1173 -0.5429 0.537
SW13 GDSC1 2.3675 4.0339 -0.5088 0.4274
LB1047-RCC GDSC1 2.3871 4.548 -0.6914 1.0748
A-704 GDSC1 2.4396 4.182 -0.5343 0.4663
KTCTL-195 GDSC1 2.5187 4.6996 -0.6936 0.9756
KTCTL-13 GDSC1 2.5201 4.3787 -0.5742 0.5452
SW156 GDSC1 2.6084 4.9215 -0.7402 1.0936
LB996-RCC GDSC1 2.6556 4.8908 -0.7089 0.9314
KTCTL-140 GDSC1 2.6586 4.8997 -0.711 0.9372
LB2241-RCC GDSC1 2.7565 4.7138 -0.6039 0.5121
NCC021 GDSC1 2.8123 4.6478 -0.5597 0.3688
HA7-RCC GDSC1 2.9411 4.7829 -0.5598 0.3217
TK-10 GDSC1 2.9773 4.9099 -0.5908 0.3806
BB65-RCC GDSC1 3.1514 5.1831 -0.6225 0.3904
UO-31 GDSC1; CTRP2 4.8007 7.2654 4.2322 10.4169
TUHR4TKB CTRP2 4.91 7.4422 4.2667 9.9954
KMRC-2 CTRP2 6.0119 9.1558 4.4615 6.7161
TUHR14TKB CTRP2 6.5899 9.1629 4.9131 3.8004
RCC10RGB GDSC1; CTRP2 7.1605 11.6964 4.0859 6.3059
OS-RC-2 GDSC1; CTRP2 7.31 10.878 4.5835 4.0839
BFTC-909 GDSC1; CTRP2 7.4753 9.8924 5.1414 1.7651
TUHR10TKB CTRP2 7.4822 13.4612 3.4553 8.3589
Caki-2 CTRP2 7.582 9.4078 5.4056 0.8081
769-P GDSC1; CTRP2 7.6021 10.2496 5.0543 1.9469
VMRC-RCW GDSC1; CTRP2 7.6468 9.7981 5.2748 1.1601
VMRC-RCZ GDSC1; CTRP2 7.7596 12.3369 4.1871 5.0463
KMRC-3 CTRP2 7.9344 9.8657 5.3854 0.645
ACHN GDSC1; CTRP2 7.9461 9.5711 5.504 0.3629
786-O GDSC1; CTRP2 8.4524 10.5652 5.3394 0.5033
KMRC-1 GDSC1; CTRP2 8.4684 9.853 5.6009 0.0887
KMRC-20 GDSC1; CTRP2 8.6427 10.0713 5.5878 0.0789
Caki-1 GDSC1; CTRP2 8.8389 10.4761 5.5192 0.1153
SNU-1272 CTRP2 14.4971 28.5024 0.8316 8.9428
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 GDSC1 0.6113 7.2394 -3.0995 20.5681
SNU-1040 GDSC1 1.2577 5.3458 -1.6841 9.5462
GP5d GDSC1 1.2892 6.0193 -1.9879 11.5728
SW626 GDSC1 1.3135 3.8048 -0.9217 3.9695
SW1116 GDSC1 1.9327 3.6961 -0.5589 0.9004
SW1463 GDSC1 1.9895 3.8934 -0.6106 1.0785
SW837 GDSC1 2.2401 4.321 -0.6673 1.0998
CaR-1 GDSC1 2.3407 4.1854 -0.5742 0.6519
HCC2998 GDSC1 2.5365 4.4456 -0.5921 0.5931
COLO 320HSR GDSC1 2.5834 4.394 -0.5555 0.4568
SNU-C2B GDSC1 3.2249 5.9223 -0.8615 1.0988
T84 GDSC1; CTRP2 3.987 8.6383 2.7943 18.2011
LS1034 GDSC1; CTRP2 4.0399 8.6058 2.8625 17.7982
COLO 320 CTRP2 4.7436 9.9093 2.9439 15.7357
KM12 GDSC1; CTRP2 4.842 10.4076 2.7945 16.1012
SNU-81 GDSC1; CTRP2 5.1125 11.3407 2.5845 16.317
C2BBe1 GDSC1; CTRP2 6.0583 8.4777 4.8393 5.0385
CL-11 GDSC1; CTRP2 6.5627 11.8694 3.5518 9.493
NCI-H747 GDSC1; CTRP2 7.1365 9.3627 5.1829 1.977
GP2d CTRP2 7.1798 9.2822 5.2452 1.6982
LoVo GDSC1; CTRP2 7.1883 9.5348 5.1353 2.0962
SW48 GDSC1; CTRP2 7.346 9.3311 5.3171 1.279
MDST8 GDSC1; CTRP2 7.3841 8.6891 5.6024 0.3943
SNU-407 GDSC1; CTRP2 7.4144 16.0213 2.1466 13.5267
HT115 GDSC1; CTRP2 7.4894 9.2099 5.4421 0.7651
HT-29 GDSC1; CTRP2 7.5074 8.8264 5.6026 0.3352
OUMS-23 CTRP2 7.5349 8.5485 5.7156 0.1191
CW-2 GDSC1; CTRP2 7.5546 10.2279 5.0369 2.0577
HCC-56 CTRP2 7.6631 8.934 5.6261 0.2278
SNU-C5 GDSC1; CTRP2 7.6704 10.8004 4.846 2.6301
DLD-1 CTRP2 7.6731 8.8087 5.6752 0.1443
LS123 GDSC1; CTRP2 7.81 9.808 5.3511 0.8122
HT-55 GDSC1; CTRP2 7.8283 9.1489 5.6125 0.2007
SW948 GDSC1; CTRP2 7.9255 9.3911 5.5625 0.2573
LS411N GDSC1; CTRP2 7.933 9.4826 5.5317 0.3122
NCI-H508 CTRP2 7.9979 9.5412 5.5361 0.2813
COLO 678 GDSC1; CTRP2 8.0812 10.3515 5.2586 0.8977
SNU-1033 CTRP2 8.0893 10.105 5.3604 0.6248
COLO205 GDSC1; CTRP2 8.1005 9.1029 5.7257 0.0333
SK-CO-1 CTRP2 8.1136 9.7956 5.4885 0.3308
SW620 GDSC1; CTRP2 8.1337 9.6685 5.5429 0.2281
SNU-C4 CTRP2 8.172 9.2686 5.6949 0.0465
COLO201 CTRP2 8.1972 9.3966 5.6607 0.0698
SNU-C1 GDSC1; CTRP2 8.2179 9.7662 5.54 0.21
SW1417 GDSC1; CTRP2 8.2195 9.6373 5.5861 0.1452
LS513 GDSC1; CTRP2 8.3041 9.7725 5.5699 0.1489
LS180 GDSC1; CTRP2 8.306 10.1023 5.4524 0.3321
HCT 15 GDSC1; CTRP2 8.3713 10.0398 5.5005 0.2308
HCT 116 GDSC1; CTRP2 8.4217 9.6209 5.6626 0.0464
SNU-61 GDSC1; CTRP2 8.4271 16.6544 2.5699 10.3573
CCK-81 GDSC1; CTRP2 8.5014 10.4532 5.4011 0.3611
RCM-1 [Human ESC] GDSC1; CTRP2 8.5052 9.6149 5.6924 0.0257
RKO GDSC1; CTRP2 8.6123 10.2663 5.5103 0.1628
SNU-503 CTRP2 8.6732 10.5321 5.4393 0.2466
NCI-H716 GDSC1; CTRP2 9.2391 20.4496 1.2992 13.6126
SNU-C2A CTRP2 9.9464 20.9997 1.5153 11.9204
HCT 8 CTRP2 11.8652 25.2808 0.7362 11.9418
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -0.5541 7.7962 -4.3473 30.4289
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC1 2.0385 3.4138 -0.4122 0.3119
Huh-7 GDSC1 2.1974 4.0232 -0.572 0.7418
JHH-7 GDSC1 2.2714 3.9216 -0.5052 0.4658
HLE GDSC1 2.422 4.1695 -0.5366 0.4819
SNU-182 CTRP2 2.4709 7.2659 1.7539 26.3141
SNU-886 CTRP2 4.2857 13.783 0.6268 25.0984
SNU-878 CTRP2 5.1561 9.3307 3.6128 12.0679
JHH-5 CTRP2 5.1602 8.9853 3.7848 11.351
Li-7 CTRP2 5.2801 14.5543 1.1369 21.2062
HuH-6 CTRP2 6.5052 12.5284 3.178 11.1237
Hep 3B2.1-7 GDSC1; CTRP2 6.6185 10.2753 4.3863 5.9361
SNU-387 GDSC1; CTRP2 7.2056 13.9897 2.9931 10.6424
JHH-4 GDSC1; CTRP2 7.4037 11.507 4.346 4.9004
SNU-449 GDSC1; CTRP2 7.4067 11.321 4.4368 4.5345
JHH-6 GDSC1; CTRP2 7.487 8.2983 5.7848 0.049
JHH-1 GDSC1; CTRP2 7.5542 8.8542 5.6117 0.2958
SK-HEP-1 GDSC1; CTRP2 7.6086 9.7822 5.2619 1.2329
SNU-761 CTRP2 7.7458 12.5389 4.0822 5.4773
SNU-398 GDSC1; CTRP2 7.7632 10.0531 5.2264 1.2205
SNU-475 GDSC1; CTRP2 7.8277 9.0159 5.6597 0.1308
HLF CTRP2 7.8537 9.1094 5.6363 0.1573
Hep-G2 CTRP2 8.0434 9.4534 5.5855 0.1857
HuH-1 GDSC1; CTRP2 8.0645 9.4659 5.589 0.1753
SNU-423 GDSC1; CTRP2 8.2972 9.8649 5.5348 0.198
PLC/PRF/5 CTRP2 8.3569 9.6054 5.6457 0.0641
JHH-2 GDSC1; CTRP2 8.3863 10.262 5.4256 0.3547
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 210 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1703 GDSC1; CTRP2 -1.2175 11.9259 -4.0065 49.0989
IST-SL1 GDSC1 -0.3408 2.5912 -1.5689 14.0151
NCI-H1993 GDSC1 0.2012 6.2647 -2.943 21.1389
NCI-H1437 GDSC1 0.4092 4.0109 -1.6509 11.8691
COR-L321 GDSC1 0.4883 2.9674 -1.0733 7.2135
UMC-11 GDSC1 0.4956 2.7541 -0.963 6.3395
RERF-LC-KJ GDSC1 0.8166 2.9394 -0.8296 4.444
NCI-H2135 GDSC1 1.0331 2.635 -0.5583 2.0633
NCI-H1436 GDSC1 1.0588 3.3573 -0.8709 4.1668
SBC-3 GDSC1 1.0647 2.9032 -0.6598 2.6782
IST-SL2 GDSC1 1.0766 3.3723 -0.8668 4.0973
COR-L311 GDSC1 1.0954 4.4832 -1.3801 7.7925
Ms-1 GDSC1 1.1054 3.1501 -0.7474 3.1958
NCI-H187 GDSC1 1.1371 2.8973 -0.6163 2.2539
NCI-H322M GDSC1 1.1945 3.8607 -1.0202 4.9256
NCI-H1304 GDSC1 1.2359 2.959 -0.5898 1.9174
Lu-165 GDSC1 1.2542 8.5062 -3.233 19.2219
COR-L88 GDSC1 1.2869 3.6264 -0.8565 3.5748
NCI-H345 GDSC1 1.3029 2.3962 -0.3298 0.4679
NCI-H847 GDSC1 1.3055 7.1726 -2.5389 15.1064
NCI-H596 GDSC1 1.3452 8.8683 -3.3435 19.5197
DMS 79 GDSC1 1.351 8.4975 -3.1564 18.5241
NCI-H524 GDSC1 1.3656 4.5336 -1.2264 5.9998
NCI-H2227 GDSC1 1.4273 3.2813 -0.6279 1.8509
NCI-H1648 GDSC1 1.4321 4.0106 -0.9452 3.8875
NCI-H2804 GDSC1 1.4507 4.2087 -1.024 4.3893
CPC-N GDSC1 1.4607 3.498 -0.703 2.2538
NCI-H1836 GDSC1 1.4958 3.2029 -0.5613 1.3774
LK-2 GDSC1 1.5239 5.6912 -1.6699 8.7467
NCI-H2171 GDSC1 1.5779 2.895 -0.4037 0.55
NCI-H720 GDSC1 1.6043 2.7601 -0.3435 0.3242
NCI-H2731 GDSC1 1.614 5.2248 -1.3924 6.5913
COR-L303 GDSC1 1.6224 3.299 -0.5409 1.1214
LC-2/ad GDSC1 1.6573 5.3288 -1.4137 6.6398
Lu-139 GDSC1 1.6788 9.2235 -3.2723 18.1791
NCI-H513 GDSC1 1.7045 4.3635 -0.948 3.3889
NCI-H2818 GDSC1 1.7092 5.3449 -1.389 6.3519
NCI-H64 GDSC1 1.7222 2.7678 -0.3025 0.169
NCI-H2369 GDSC1 1.7509 3.1826 -0.4404 0.5644
NCI-H3255 GDSC1 1.7588 4.2387 -0.8644 2.7678
Lu-135 GDSC1 1.8083 6.6624 -1.9436 9.8931
NCI-H1876 GDSC1 1.81 3.6589 -0.5985 1.2031
HCC33 GDSC1 1.8521 3.742 -0.6124 1.2261
NCI-H2461 GDSC1 1.9566 4.2117 -0.7531 1.8327
COR-L23 GDSC1 1.9613 3.3247 -0.4096 0.3399
SBC-1 GDSC1 1.9695 3.8731 -0.6115 1.102
NCI-H82 GDSC1 1.9839 3.6118 -0.5055 0.6436
NCI-H510A GDSC1 1.988 3.6956 -0.5353 0.7561
NCI-H2803 GDSC1 2.0317 3.7958 -0.555 0.8008
Lu-134-A GDSC1 2.055 9.2396 -3.0126 15.7581
NCI-H1688 GDSC1 2.19 7.5441 -2.1121 10.059
NCI-H2722 GDSC1 2.2176 3.8677 -0.5066 0.4993
NCI-H1770 GDSC1 2.2526 3.4891 -0.3613 0.1352
A-427 GDSC1 2.2649 4.6783 -0.7969 1.6916
NCI-H1975 GDSC1 2.286 4.0262 -0.5375 0.5604
NCI-H1048 GDSC1 2.3685 4.5925 -0.7166 1.2012
NCI-H1693 GDSC1 2.3901 4.4224 -0.6424 0.8716
NCI-H1781 GDSC1 2.3919 3.8042 -0.4195 0.2025
NCI-H2869 GDSC1 2.4459 5.0898 -0.8783 1.8987
EMC-BAC-1 GDSC1 2.451 6.8055 -1.6125 6.2825
EMC-BAC-2 GDSC1 2.4798 4.516 -0.6407 0.7992
Lu-99A GDSC1 2.5121 4.6018 -0.6595 0.8472
NCI-H209 GDSC1 2.5346 14.291 -5.1329 23.7476
SW1573 GDSC1 2.553 4.8626 -0.7412 1.1445
NCI-H3122 GDSC1 2.616 5.0367 -0.7811 1.2614
NCI-H2347 GDSC1 2.6267 4.7591 -0.6715 0.8112
NCI-H2595 GDSC1 2.6406 4.7344 -0.6567 0.7487
PaCa-3 GDSC1 2.7403 5.0257 -0.7246 0.9295
NCI-H2591 GDSC1 2.7906 4.826 -0.6312 0.5762
NCI-H748 GDSC1 2.8202 16.5515 -6.0333 25.8618
LC-1/sq GDSC1 2.8678 5.1441 -0.7169 0.8136
NCI-H2373 GDSC1 2.8912 4.7394 -0.5628 0.3464
NCI-H211 GDSC1; CTRP2 2.9822 8.7357 1.7172 24.9376
RERF-LC-Sq1 GDSC1 2.9824 5.2732 -0.7188 0.7485
NCI-H2795 GDSC1 3.035 4.8741 -0.5575 0.2861
ABC-1 GDSC1 3.1812 5.064 -0.5706 0.2688
NCI-H290 GDSC1 3.4798 16.0304 -5.3061 22.1247
NCI-H810 GDSC1; CTRP2 3.5346 6.8797 3.0392 18.5018
NCI-H522 GDSC1; CTRP2 4.2886 9.3195 2.7844 17.47
HCC44 GDSC1; CTRP2 4.3434 6.6358 3.9985 12.5755
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 4.3528 6.6603 3.9998 12.5439
NCI-H1666 GDSC1; CTRP2 4.5563 7.727 3.7795 12.8446
HCC15 GDSC1; CTRP2 4.5676 8.1114 3.6192 13.4534
Lu-99 CTRP2 4.5984 8.6424 3.4058 14.231
HCC1171 CTRP2 4.8356 8.5358 3.689 12.5075
Calu-3 GDSC1; CTRP2 5.1476 8.246 4.1293 9.9658
DV-90 CTRP2 5.1526 8.2452 4.1344 9.933
HOP-92 GDSC1; CTRP2 5.1643 7.7676 4.3721 8.9352
PC-14 GDSC1; CTRP2 5.1871 7.0265 4.734 7.4226
NCI-H446 GDSC1; CTRP2 5.2296 11.0533 2.8323 15.0782
SK-MES-1 GDSC1; CTRP2 5.2657 8.2171 4.2563 9.1674
SW1271 GDSC1; CTRP2 5.4386 7.0463 4.979 5.8034
NCI-H1355 GDSC1; CTRP2 5.4863 7.9018 4.6176 7.1693
NCI-H1915 GDSC1; CTRP2 5.6102 8.8692 4.2556 8.4007
DMS 454 CTRP2 5.6852 8.9237 4.2954 8.0753
NCI-H1155 GDSC1; CTRP2 5.7024 9.8712 3.839 9.9464
NCI-H226 GDSC1; CTRP2 5.7709 6.5486 5.5393 2.7176
NCI-H358 GDSC1; CTRP2 5.7885 9.3064 4.1955 8.2789
HCC4006 CTRP2 5.794 12.3617 2.6747 14.5124
NCI-H1092 GDSC1; CTRP2 5.821 12.4273 2.6649 14.4964
NCI-H647 GDSC1; CTRP2 5.833 14.3775 1.7004 18.1012
NCI-H2106 CTRP2 5.8505 11.8154 2.9958 13.1165
RERF-LC-A1 CTRP2 5.8506 8.552 4.6256 6.3486
CAL-12T GDSC1; CTRP2 5.9911 8.6464 4.6988 5.7598
NCI-H1694 GDSC1; CTRP2 6.088 7.4436 5.3808 2.7062
NCI-H1385 CTRP2 6.1076 9.3657 4.4361 6.6387
HCC1588 CTRP2 6.1995 12.725 2.8324 13.0851
NCI-H1105 CTRP2 6.3183 8.7101 4.9323 4.1718
NCI-H1563 GDSC1; CTRP2 6.3467 9.137 4.7422 4.9173
NCI-H1650 GDSC1; CTRP2 6.3626 10.5004 4.0757 7.6774
NCI-H2087 GDSC1; CTRP2 6.459 12.1969 3.3065 10.6853
NCI-H2170 GDSC1; CTRP2 6.4802 8.1763 5.3162 2.3152
LUDLU-1 CTRP2 6.556 10.7325 4.1118 7.1843
RERF-LC-Ad1 CTRP2 6.6157 8.5805 5.2151 2.5252
NCI-H2081 GDSC1; CTRP2 6.7232 13.5842 2.8242 12.1448
COR-L95 GDSC1; CTRP2 6.7453 9.4923 4.8638 3.7618
DMS 53 GDSC1; CTRP2 6.7779 11.1293 4.0844 6.922
DMS 114 GDSC1; CTRP2 6.8203 10.4974 4.4268 5.4396
NCI-H2122 GDSC1; CTRP2 6.8759 8.4885 5.4261 1.365
SBC-5 GDSC1; CTRP2 6.8828 8.0907 5.6066 0.721
HCC2935 CTRP2 6.8914 9.295 5.0593 2.763
ChaGo-K-1 GDSC1; CTRP2 6.9751 12.6213 3.4957 9.0106
VMRC-LCD CTRP2 7.0012 9.8838 4.8516 3.4397
Calu-1 CTRP2 7.006 9.8863 4.8536 3.4251
NCI-H1838 GDSC1; CTRP2 7.13 9.8049 4.9736 2.7862
NCI-H1573 GDSC1; CTRP2 7.1593 13.9472 2.9793 10.7743
NCI-H1734 GDSC1; CTRP2 7.1699 11.441 4.2168 5.7594
NCI-H2444 GDSC1; CTRP2 7.1733 8.5255 5.5705 0.6075
LOU-NH91 GDSC1; CTRP2 7.21 14.671 2.6598 11.9372
NCI-H1581 GDSC1; CTRP2 7.2154 10.4586 4.7204 3.6693
NCI-H2029 GDSC1; CTRP2 7.2467 9.8506 5.0255 2.4426
NCI-H841 GDSC1; CTRP2 7.2539 16.0317 2.0195 14.2676
HCC2279 CTRP2 7.2935 10.5016 4.751 3.4454
NCI-H1184 CTRP2 7.3016 12.3188 3.8832 6.9136
NCI-H2405 GDSC1; CTRP2 7.3111 9.4822 5.2311 1.6122
NCI-H1793 GDSC1; CTRP2 7.3134 10.535 4.7481 3.4308
NCI-H292 GDSC1; CTRP2 7.3286 10.611 4.7221 3.5129
HCC78 GDSC1; CTRP2 7.3459 9.3503 5.3087 1.3077
NCI-H2085 GDSC1; CTRP2 7.3944 12.6599 3.783 7.1773
NCI-H322 CTRP2 7.4006 10.3023 4.9115 2.6931
NCI-H889 CTRP2 7.4073 11.2101 4.49 4.323
COLO 668 GDSC1; CTRP2 7.4099 12.0251 4.1014 5.8718
COLO 699 CTRP2 7.4355 16.5979 1.8774 14.4684
NCI-H2291 GDSC1; CTRP2 7.501 9.7597 5.2142 1.4868
DMS 273 GDSC1; CTRP2 7.5206 15.4979 2.4844 12.0884
NCI-H69 GDSC1; CTRP2 7.5288 9.5965 5.2997 1.1769
BEN GDSC1; CTRP2 7.5339 8.5223 5.7244 0.1074
MOR/CPR CTRP2 7.5601 8.5846 5.7122 0.1181
LCLC-103H GDSC1; CTRP2 7.5618 8.7952 5.6368 0.2425
NCI-H2009 GDSC1; CTRP2 7.6435 9.9185 5.2217 1.3344
NCI-H2228 GDSC1; CTRP2 7.657 15.7707 2.451 11.9913
EKVX GDSC1; CTRP2 7.7098 10.7578 4.8884 2.4318
EPLC-272H GDSC1; CTRP2 7.7105 9.9549 5.241 1.2165
NCI-H2023 GDSC1; CTRP2 7.7369 11.1631 4.7202 3.0228
NCI-H1341 CTRP2 7.7507 9.5344 5.4335 0.6237
NCI-H2110 GDSC1; CTRP2 7.7563 13.0735 3.8339 6.4446
NCI-H460 GDSC1; CTRP2 7.7603 9.0209 5.6325 0.1874
EBC-1 GDSC1; CTRP2 7.7651 10.0643 5.2226 1.231
HCC366 CTRP2 7.7815 10.1072 5.2128 1.2489
NCI-H1755 GDSC1; CTRP2 7.7858 11.9227 4.3988 4.1881
NCI-H2126 CTRP2 7.8145 9.3399 5.5366 0.3478
RERF-LC-MS GDSC1; CTRP2 7.8311 12.766 4.0306 5.5652
HOP-62 GDSC1; CTRP2 7.8475 11.071 4.8272 2.5083
SHP-77 GDSC1; CTRP2 7.8544 9.2797 5.5751 0.2576
KNS-62 CTRP2 7.8875 11.8856 4.4795 3.7544
NCI-H727 GDSC1; CTRP2 7.8985 10.6873 5.0253 1.7644
NCI-H2342 GDSC1; CTRP2 7.8993 10.5721 5.0756 1.5957
IA-LM GDSC1; CTRP2 7.9137 9.1779 5.6345 0.1459
NCI-H2286 CTRP2 7.92 14.2056 3.4014 7.9167
NCI-H2172 GDSC1; CTRP2 7.9505 9.4383 5.5551 0.2624
NCI-H2030 GDSC1; CTRP2 7.9693 9.7559 5.4436 0.4853
T3M-10 CTRP2 7.983 14.7237 3.1949 8.6313
LC-1/sq-SF CTRP2 8.0083 9.0925 5.6978 0.0609
Sq-1 CTRP2 8.0109 9.1609 5.6755 0.0805
NCI-H1339 CTRP2 8.015 9.2948 5.6309 0.1295
Calu-6 GDSC1; CTRP2 8.0216 9.7529 5.4668 0.4104
NCI-H1435 GDSC1; CTRP2 8.0362 9.524 5.5574 0.232
RERF-LC-Ad2 CTRP2 8.0777 9.4158 5.6116 0.1414
NCI-H650 GDSC1; CTRP2 8.1121 9.7214 5.5153 0.2817
NCI-H838 GDSC1; CTRP2 8.1149 9.5099 5.5923 0.1592
NCI-H1373 CTRP2 8.1184 10.0105 5.4096 0.4942
Lu-65 GDSC1; CTRP2 8.1226 13.6604 3.7979 6.0853
NCI-H526 GDSC1; CTRP2 8.127 9.4692 5.611 0.1324
NCI-H2196 GDSC1; CTRP2 8.1283 18.0146 1.6947 13.9689
NCI-H1568 GDSC1; CTRP2 8.1533 10.1857 5.3571 0.6002
LCLC-97TM1 GDSC1; CTRP2 8.1882 12.9073 4.1924 4.4845
NCI-H2141 GDSC1; CTRP2 8.1943 10.0106 5.4413 0.3942
NCI-H1299 GDSC1; CTRP2 8.1955 10.0089 5.4424 0.3915
NCI-H23 GDSC1; CTRP2 8.1962 14.9906 3.2126 8.2546
LXF 289 GDSC1; CTRP2 8.2211 12.7269 4.2958 4.0559
HCC1438 CTRP2 8.2565 12.3794 4.4753 3.3515
NCI-H1623 GDSC1; CTRP2 8.3361 10.4625 5.3293 0.5772
NCI-H441 GDSC1; CTRP2 8.3376 10.718 5.2301 0.8206
SK-LU-1 GDSC1; CTRP2 8.3435 9.8052 5.5729 0.1377
HCC1195 CTRP2 8.4334 14.2174 3.736 5.9212
NCI-H1792 GDSC1; CTRP2 8.5193 12.8001 4.438 3.2102
NCI-H1944 GDSC1; CTRP2 8.5268 18.0372 1.9697 12.386
NCI-H1651 GDSC1; CTRP2 8.5949 10.2843 5.4976 0.1825
NCI-H196 GDSC1; CTRP2 8.6512 13.8546 4.0386 4.521
NCI-H1395 CTRP2 8.9126 11.6085 5.1361 0.7534
NCI-H661 GDSC1; CTRP2 9.0171 11.0662 5.3789 0.2513
A-549 GDSC1; CTRP2 9.0381 10.81 5.4756 0.1296
LK2 CTRP2 9.0689 15.2283 3.6612 5.4354
COR-L105 GDSC1; CTRP2 9.1724 11.3748 5.3277 0.2884
HCC1833 CTRP2 9.1897 20.2016 1.3847 13.4036
NCI-H520 GDSC1; CTRP2 9.3338 16.6231 3.1803 6.8855
HCC827 GDSC1; CTRP2 10.1671 19.7217 2.2602 9.134
NCI-H1869 GDSC1; CTRP2 10.2612 18.972 2.6652 7.6262
HCC2108 CTRP2 11.8153 23.3024 1.6186 9.3265
Hs 888.Lu CTRP2 8.6608 11.1044 5.2219 0.6732
⏷ Show the Full List of 210 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.0918 4.3676 -0.7524 1.6635
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.1188 11.6461 4.0806 6.3917
SYO-1 CTRP2 12.5109 30.9548 -1.5214 17.1022
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 7.4627 13.7568 3.2969 9.0208
Aska-SS CTRP2 8.8079 20.74 0.853 15.6848
A-204 GDSC1; CTRP2 0.2037 10.3654 -1.8696 42.6107
SW684 GDSC1 1.3898 2.706 -0.4114 0.7411
G-402 GDSC1; CTRP2 1.6752 12.9 -1.4685 37.1708
Hs 633.T GDSC1 1.9644 3.4832 -0.4658 0.5139
EW-8 GDSC1 1.985 3.5799 -0.4932 0.5974
VA-ES-BJ GDSC1 2.2119 3.5943 -0.4117 0.2431
SW872 GDSC1 2.3799 3.8034 -0.4234 0.2139
Rh30 GDSC1 2.4267 4.0318 -0.4858 0.3389
MFH-ino GDSC1 2.8804 4.3758 -0.4427 0.1289
TE 617.T CTRP2 4.449 9.0768 3.0558 15.9996
Hs 729.T CTRP2 5.3813 8.0804 4.432 8.176
KYM-1 GDSC1; CTRP2 5.5345 8.6393 4.3008 8.3759
GCT GDSC1; CTRP2 6.4089 9.9124 4.4051 6.2175
HT-1080 GDSC1; CTRP2 6.6532 9.0705 5.0038 3.3296
SK-LMS-1 GDSC1; CTRP2 6.9055 9.0598 5.1797 2.2698
Rh41 GDSC1; CTRP2 6.9996 11.2536 4.1866 6.1438
Rh18 CTRP2 7.0103 9.0041 5.2711 1.7912
BT-12 CTRP2 7.2042 8.2915 5.6782 0.3021
TE 441.T GDSC1; CTRP2 7.5264 9.0031 5.5425 0.4682
SW982 GDSC1; CTRP2 7.5983 9.3791 5.4251 0.7406
RKN GDSC1; CTRP2 8.0465 9.078 5.7157 0.0436
RD GDSC1; CTRP2 8.07 10.8664 5.0388 1.5714
Tm87-16 CTRP2 8.0994 18.1018 1.6307 14.2368
SK-UT-1 GDSC1; CTRP2 8.2914 9.982 5.4906 0.2691
TTC-709 CTRP2 8.2953 18.1419 1.7535 13.5008
G-401 GDSC1; CTRP2 8.774 17.0971 2.5941 9.7711
MES-SA GDSC1; CTRP2 10.9151 19.7602 2.6946 6.8079
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.7564 9.1368 5.5887 0.2657
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.0572 33.228 -5.9086 30.9221
Caov-4 GDSC1 0.8547 3.4731 -1.0588 6.0536
OVKATE GDSC1 1.1105 4.275 -1.2702 6.9476
ES-2 GDSC1 1.9896 3.4174 -0.432 0.3912
OVCAR-3 GDSC1 1.9979 3.6497 -0.5139 0.6653
A2780 GDSC1; CTRP2 3.5952 7.946 2.6888 19.6557
SNU-119 CTRP2 5.0542 8.5095 3.9135 11.0698
OC 314 GDSC1; CTRP2 5.9685 10.0962 3.9549 8.9261
COV362 CTRP2 6.4103 8.4474 5.1326 3.1818
EFO-27 GDSC1; CTRP2 6.8502 8.5542 5.3805 1.5652
COV434 CTRP2 6.8839 13.4353 3.0232 11.071
MCAS CTRP2 6.9336 8.7221 5.354 1.5684
OAW42 GDSC1; CTRP2 6.9347 9.9853 4.7575 3.9133
ONCO-DG-1 CTRP2 7.0401 9.4476 5.0837 2.4721
RMG-I GDSC1; CTRP2 7.1096 10.2166 4.7653 3.6346
Caov-3 GDSC1; CTRP2 7.3076 10.6799 4.6759 3.7219
OVISE GDSC1; CTRP2 7.4519 8.9147 5.5439 0.5057
OVCAR-5 GDSC1; CTRP2 7.4986 11.1681 4.5694 3.8901
Kuramochi GDSC1; CTRP2 7.532 9.8053 5.2112 1.4684
OV7 CTRP2 7.5357 9.4539 5.3636 0.9683
TYK-nu GDSC1; CTRP2 7.63 13.0989 3.7352 7.0182
TOV-112D GDSC1; CTRP2 7.6393 16.5426 2.0579 13.474
OV56 GDSC1; CTRP2 7.6643 9.0326 5.59 0.2969
OVK18 GDSC1; CTRP2 7.7523 9.3385 5.5109 0.4315
FU-OV-1 GDSC1; CTRP2 7.7849 10.0101 5.2555 1.1128
ES2 CTRP2 7.8395 9.2954 5.5634 0.2846
TOV-21G GDSC1; CTRP2 7.8655 9.1514 5.6258 0.1699
SNU-8 CTRP2 7.8694 9.0752 5.6542 0.1291
SK-OV-3 GDSC1; CTRP2 7.8837 10.19 5.2296 1.1181
JHOM-1 CTRP2 7.9602 9.2871 5.6133 0.1652
JHOC-5 CTRP2 7.961 9.9337 5.3705 0.6687
OAW28 GDSC1; CTRP2 8.0131 13.0324 4.0233 5.3533
OVTOKO GDSC1; CTRP2 8.0154 10.2579 5.2655 0.9205
EFO-21 GDSC1; CTRP2 8.067 9.8632 5.444 0.4405
HEY A8 CTRP2 8.0835 9.7196 5.5046 0.3108
DOV13 GDSC1; CTRP2 8.1121 9.6694 5.5342 0.2486
OVCAR-4 GDSC1; CTRP2 8.1955 9.8309 5.5081 0.2682
SNU-840 CTRP2 8.2273 12.4865 4.4095 3.6254
JHOS-2 GDSC1; CTRP2 8.3297 9.8459 5.5536 0.1646
IGROV-1 GDSC1; CTRP2 8.5651 10.2599 5.4952 0.1921
OVCAR-8 GDSC1; CTRP2 8.5936 9.9233 5.6204 0.0593
OV-90 GDSC1; CTRP2 8.8362 10.5476 5.4938 0.1421
COV644 CTRP2 9.826 19.6532 2.0745 10.2009
OVSAHO CTRP2 16.7975 36.783 -1.5576 12.7393
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 2.5294 4.3308 -0.5534 0.4773
NCI-H2452 GDSC1; CTRP2 4.4589 6.9318 4.0109 12.2028
NCI-H28 GDSC1; CTRP2 6.4156 11.4561 3.6413 9.3882
MSTO-211H GDSC1; CTRP2 6.6001 11.6665 3.682 8.89
NCI-H2052 GDSC1; CTRP2 8.2055 10.0156 5.444 0.3845
JL-1 CTRP2 8.2689 9.5807 5.6234 0.0947
ACC-MESO-1 CTRP2 8.4813 9.7417 5.6427 0.0542
IST-Mes1 GDSC1; CTRP2 11.2541 21.4996 2.1058 8.3893
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 2.2172 4.6727 -0.8169 1.8505
DU145 GDSC1; CTRP2 7.2864 10.285 4.8482 3.0752
LNCaP clone FGC GDSC1; CTRP2 7.6925 11.4523 4.5594 3.685
PaCa-3 CTRP2 7.828 9.4531 5.4993 0.4231
VCaP GDSC1; CTRP2 8.0663 9.7708 5.4785 0.3681
22Rv1 GDSC1; CTRP2 8.1666 12.659 4.2938 4.1268
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 7.0937 11.3239 4.2198 5.8628
YD-15 CTRP2 7.2759 8.557 5.606 0.4436
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.9686 3.8643 -0.6085 1.0889
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1 1.2627 3.8278 -0.9628 4.3649
SCH GDSC1 1.6044 2.9894 -0.4283 0.627
RF-48 GDSC1 1.7062 4.7377 -1.1135 4.4777
TMK-1 GDSC1 2.2614 4.3547 -0.671 1.0972
OCUM-1 GDSC1 2.3115 4.2408 -0.6066 0.7911
TGBC11TKB GDSC1 2.5019 4.123 -0.4901 0.3197
GCIY GDSC1 2.6427 4.3997 -0.5352 0.3758
HGC-27 GDSC1; CTRP2 2.9565 6.8343 2.4299 22.443
RERF-GC-1B GDSC1 3.276 5.565 -0.7108 0.5669
MKN28 GDSC1 3.5146 5.7025 -0.671 0.372
SNU-16 GDSC1; CTRP2 5.0512 9.9024 3.2359 13.8475
ECC10 GDSC1; CTRP2 5.3334 9.4106 3.7374 11.157
MKN1 GDSC1; CTRP2 5.9947 8.0048 3.3981 0.8896
SNU-620 CTRP2 6.9621 8.2625 5.5745 0.7587
GSU CTRP2 7.0094 7.8408 5.7676 0.1895
MKN74 CTRP2 7.0505 13.2347 3.2494 9.8805
MKN45 GDSC1; CTRP2 7.1642 8.2186 5.6891 0.2958
NUGC-4 GDSC1; CTRP2 7.1946 10.9645 4.4644 4.721
KE-39 CTRP2 7.2123 11.2746 4.327 5.2499
SNU-216 CTRP2 7.4437 11.7378 4.2625 5.1778
MKN7 GDSC1; CTRP2 7.4897 12.3822 3.9841 6.2268
AGS GDSC1; CTRP2 7.6034 9.0837 5.5449 0.4231
SNU-668 CTRP2 7.6088 9.5892 5.3435 0.9749
ECC12 CTRP2 7.6504 9.0333 5.5841 0.3147
NUGC-3 GDSC1; CTRP2 7.67 9.5966 5.3705 0.85
GSS CTRP2 7.6705 13.387 3.624 7.4016
SH-10-TC CTRP2 8.0006 12.2325 4.3889 3.9637
SNU-5 GDSC1; CTRP2 8.0102 9.21 5.6585 0.098
SNU-1 GDSC1; CTRP2 8.0224 10.0184 5.3647 0.6497
23132/87 GDSC1; CTRP2 8.2269 9.5395 5.6226 0.1018
Hs 746.T GDSC1; CTRP2 8.3064 9.8856 5.5309 0.2015
SNU-601 CTRP2 8.3139 9.7996 5.564 0.1543
SNU-719 CTRP2 8.4416 13.8951 3.8916 5.3189
Fu97 GDSC1; CTRP2 8.5266 17.9091 2.0318 12.1662
IM95 GDSC1; CTRP2 8.5606 10.4292 5.4331 0.2866
NCI-N87 GDSC1; CTRP2 8.5616 10.6095 5.3676 0.4036
HuG1-N CTRP2 8.6657 14.6515 3.6799 5.8445
LMSU CTRP2 9.4867 27.0426 -1.7422 21.6152
SNU-685 CTRP2 7.2045 9.3355 5.2356 1.7067
SNU-1077 CTRP2 7.6247 10.0485 5.1554 1.5732
SNG-M GDSC1; CTRP2 7.6906 9.5002 5.4196 0.6971
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 1.0522 17.6905 -4.326 42.3773
ASH-3 GDSC1 1.5944 3.0888 -0.4707 0.8169
HTC-C3 GDSC1 1.891 3.8382 -0.6329 1.2852
IHH-4 GDSC1 2.2483 3.5902 -0.3972 0.2007
WRO GDSC1 2.2549 3.6208 -0.4054 0.2153
K5 GDSC1 2.6811 4.1659 -0.4409 0.1665
KMH-2 GDSC1 2.6893 4.3665 -0.5066 0.29
CGTH-W-1 GDSC1; CTRP2 2.8999 13.6334 -0.6085 31.9417
8505C GDSC1; CTRP2 4.7355 6.6555 4.4125 9.8948
ML-1 [Human leukemia] GDSC1; CTRP2 5.2527 7.5777 4.548 8.0058
CAL-62 GDSC1; CTRP2 6.5782 9.6868 4.6466 4.9219
8305C GDSC1; CTRP2 6.8659 9.3484 5.0167 2.968
TT GDSC1; CTRP2 7.1372 11.5053 4.1624 6.0302
FTC-133 GDSC1; CTRP2 7.6914 9.0787 5.5839 0.2989
B-CPAP GDSC1; CTRP2 8.0147 9.4156 5.5881 0.189
TT2609-C02 GDSC1; CTRP2 8.0825 13.7791 3.7152 6.4606
BHT-101 GDSC1; CTRP2 8.1656 9.6231 5.5712 0.177
FTC-238 CTRP2 8.2095 9.9053 5.4864 0.302
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-15A GDSC1 1.4332 4.6053 -1.2173 5.7783
PCI-38 GDSC1 1.5512 4.2464 -0.9823 3.9018
HO-1-N-1 GDSC1 1.63 3.5001 -0.6186 1.518
OSC-19 GDSC1 1.6562 3.515 -0.6122 1.4503
BICR 10 GDSC1 1.7363 3.6544 -0.6309 1.4516
SAS GDSC1 1.7818 4.4485 -0.9429 3.2209
HO-1-u-1 GDSC1 1.9195 3.7954 -0.6033 1.1128
BICR 78 GDSC1 2.0118 3.9996 -0.6423 1.204
PCI-30 GDSC1 2.0465 3.8765 -0.5795 0.8902
Ca9-22 GDSC1 2.2365 4.2118 -0.6269 0.9302
DOK GDSC1 2.2461 4.3319 -0.6689 1.1015
JHU-011 GDSC1 2.2959 4.6378 -0.7666 1.5066
BB30-HNC GDSC1 2.3445 3.986 -0.5004 0.4145
PCI-06A GDSC1 2.4222 4.7085 -0.7382 1.248
KON GDSC1 2.4321 4.3396 -0.5945 0.6645
SKN-3 GDSC1 2.4711 4.1986 -0.5283 0.4332
LB771-HNC GDSC1 2.4912 4.5015 -0.6307 0.7544
OSC-20 GDSC1 2.547 4.4494 -0.5894 0.5784
KOSC-2 GDSC1 2.6242 4.678 -0.6425 0.7094
BB49-HNC GDSC1 2.6761 4.9947 -0.7395 1.0363
SCC-15 GDSC1 2.8255 4.5907 -0.535 0.3063
NCI-H3118 GDSC1 2.8486 4.9886 -0.6676 0.6585
PCI-04B GDSC1 3.0791 5.2774 -0.6828 0.5822
CAL-33 GDSC1; CTRP2 3.0885 6.9287 2.5401 21.6502
JHU-022 GDSC1 3.149 4.9845 -0.5548 0.2479
SAT [Human HNSCC] GDSC1 3.6859 6.4464 -0.8705 0.8343
PE/CA-PJ34 (clone C12) CTRP2 4.8104 9.8083 3.0559 15.13
YD-8 CTRP2 5.0472 7.7345 4.2719 9.6287
SCC-4 GDSC1; CTRP2 5.3509 8.6138 4.1442 9.434
PE/CA-PJ15 GDSC1; CTRP2 5.4459 8.4139 4.3301 8.4504
SCC-25 GDSC1; CTRP2 6.0699 10.416 3.8798 9.043
PE/CA-PJ41 (clone D2) CTRP2 6.7103 8.405 5.3622 1.8079
FaDu GDSC1; CTRP2 6.716 9.9704 4.6091 4.8538
HSC-2 GDSC1; CTRP2 6.8396 10.0513 4.6587 4.4569
PE/CA-PJ49 CTRP2 6.8507 9.4198 4.9722 3.1677
BICR 6 CTRP2 6.8708 8.2831 5.5156 1.0454
HSC-4 GDSC1; CTRP2 7.2067 10.1766 4.848 3.1781
YD-10B CTRP2 7.3971 9.1246 5.4321 0.8623
BICR 22 GDSC1; CTRP2 7.4612 9.1455 5.455 0.7469
SCC-9 GDSC1; CTRP2 7.5752 9.2975 5.4474 0.6927
SNU-1214 CTRP2 7.6078 10.4753 4.9564 2.2932
SNU-1076 CTRP2 7.7477 8.8638 5.6835 0.1164
HSC-3 GDSC1; CTRP2 7.791 9.3348 5.5288 0.3742
SNU-899 CTRP2 7.85 10.2266 5.1973 1.2437
BICR 56 CTRP2 7.9955 10.0669 5.3332 0.7466
CAL-27 GDSC1; CTRP2 8.0107 9.1917 5.665 0.0911
BICR 16 CTRP2 8.3496 9.9615 5.5202 0.2066
SNU-1066 CTRP2 8.3748 9.8208 5.5788 0.1252
Detroit 562 GDSC1; CTRP2 8.4373 17.4862 2.1743 11.7905
BICR 31 GDSC1; CTRP2 8.4612 10.3855 5.41 0.3582
SNU-1041 CTRP2 8.5681 10.8685 5.2728 0.5995
BHY GDSC1; CTRP2 8.5856 9.9317 5.6149 0.064
SNU-46 CTRP2 8.9765 19.233 1.7049 12.639
BICR 18 CTRP2 11.3692 28.5044 -1.1176 17.5507
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW780 GDSC1 2.355 3.9407 -0.4803 0.3548
KMBC-2 CTRP2 4.8594 8.1787 3.8796 11.6773
TCCSUP GDSC1; CTRP2 4.907 7.3404 4.3089 9.8357
5637 GDSC1; CTRP2 5.4213 10.9726 3.0435 13.8139
UM-UC-1 CTRP2 5.4923 12.2502 2.4702 15.9389
HT-1197 GDSC1; CTRP2 5.7917 10.0334 3.8356 9.7779
253J-BV CTRP2 6.2651 8.8053 4.8433 4.6387
BC-3C CTRP2 6.316 11.109 3.7348 9.1833
CAL-29 GDSC1; CTRP2 7.0524 11.4358 4.1356 6.2703
253J CTRP2 7.1418 9.3294 5.2014 1.902
U-BLC1 CTRP2 7.2438 11.4155 4.2808 5.3904
KU-19-19 GDSC1; CTRP2 7.424 8.831 5.5644 0.4681
JMSU-1 CTRP2 7.4444 11.8132 4.2269 5.3192
SW1710 GDSC1; CTRP2 7.4552 9.5136 5.2965 1.2504
639V GDSC1; CTRP2 7.4757 8.4432 5.7307 0.1115
HT-1376 GDSC1; CTRP2 7.6853 9.7089 5.3315 0.9548
BFTC-905 GDSC1; CTRP2 7.8182 9.1504 5.6081 0.211
647V GDSC1; CTRP2 7.9523 9.153 5.6573 0.1092
RT-4 GDSC1; CTRP2 8.0035 9.985 5.3693 0.6482
SCaBER CTRP2 8.2269 9.6941 5.5689 0.1662
RT-112 GDSC1; CTRP2 8.2699 9.842 5.5327 0.2079
UM-UC-3 GDSC1; CTRP2 8.4114 9.9193 5.5579 0.143
T24 GDSC1; CTRP2 8.5185 13.9738 3.9029 5.1827
J82 GDSC1; CTRP2 8.6434 10.1834 5.55 0.1131
VM-CUB-1 CTRP2 8.705 14.8757 3.6001 6.0966
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-3 GDSC1 0.8563 3.9236 -1.2752 7.6712
DSH1 GDSC1 0.8776 3.6288 -1.118 6.4353
C-33 A GDSC1 0.9724 3.6824 -1.0797 5.9012
Ca Ski GDSC1 1.1331 4.1006 -1.1722 6.1734
DoTc2 4510 GDSC1 1.205 3.1847 -0.7055 2.7152
SKN GDSC1 1.2454 5.236 -1.6396 9.2637
KGN GDSC1 1.4612 4.8518 -1.3146 6.4009
SW962 GDSC1 1.4904 4.0863 -0.9455 3.7732
ME-180 GDSC1 1.5124 3.9759 -0.8837 3.3198
BPH-1 GDSC1 1.6209 4.8035 -1.1937 5.1991
OMC-1 [Human cervical carcinoma] GDSC1 1.6566 3.6693 -0.6755 1.7987
PA-1 GDSC1 1.7509 3.6783 -0.6337 1.449
C-4-I GDSC1 1.8527 3.4469 -0.4977 0.7112
HEC-1 GDSC1 1.8605 3.5484 -0.5331 0.8521
NEC8 GDSC1 1.8701 3.2215 -0.4074 0.379
MS751 GDSC1 1.8736 3.6664 -0.5731 1.0178
JAR GDSC1 1.8792 3.3303 -0.4434 0.4903
HT-3 GDSC1 1.9264 4.2975 -0.8034 2.1528
SW756 GDSC1 1.9443 3.365 -0.4306 0.4107
OVCA420 GDSC1 1.9581 3.6066 -0.5142 0.6955
SiHa GDSC1 1.9961 3.2579 -0.3732 0.2318
SKG-IIIa GDSC1 2.0131 3.9062 -0.6053 1.0322
UWB1.289 GDSC1 2.027 4.1958 -0.7134 1.5378
NCC-IT GDSC1 2.085 3.8185 -0.5414 0.707
JEG-3 GDSC1 2.1617 3.6257 -0.4412 0.335
SiSo GDSC1 2.2073 4.6066 -0.7949 1.7476
OV17R GDSC1 2.2114 4.4219 -0.7193 1.3668
NT2-D1 GDSC1 2.2183 3.9658 -0.5422 0.6183
ACC-OV7 GDSC1 2.2596 7.164 -1.8909 8.4787
SW954 GDSC1 2.3815 4.2039 -0.5648 0.5943
OVMIU GDSC1 2.3958 5.6469 -1.1342 3.3968
OVCA433 GDSC1 2.5141 4.6973 -0.6947 0.9836
PEO1 GDSC1 2.7568 4.9053 -0.6733 0.7325
LB831-BLC GDSC1 2.7742 4.3663 -0.4762 0.2041
HEY GDSC1 2.9802 4.942 -0.601 0.4044
CAL-39 GDSC1 3.074 5.1062 -0.624 0.4242
HeLa GDSC1; CTRP2 7.2615 8.3588 5.6769 0.2788
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 216993
2 ClinicalTrials.gov (NCT02039726) An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects. U.S. National Institutes of Health.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD. Mol Cancer Ther. 2014 Oct;13(10):2315-27. doi: 10.1158/1535-7163.MCT-14-0258. Epub 2014 Jul 22.
5 Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. Arch Toxicol. 2022 Jan;96(1):177-193. doi: 10.1007/s00204-021-03174-1. Epub 2021 Oct 19.