Details of the Drug

General Information of Drug (ID: DMB6FMH)

Drug Name
BMTP-11
Synonyms IL-11Ralpha targeted proapoptotic peptide (prostate cancer), MD Anderson Cancer Center; IL-11Ralpha targeted proapoptotic peptide (prostate cancer), Mercator
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Phase 1 [1]
Cross-matching ID
PubChem CID
172408051
TTD ID
D0D2YZ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 11 receptor alpha (IL11RA) TTZPLJS I11RA_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Prostate cancer
ICD Disease Classification 2C82.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 11 receptor alpha (IL11RA) DTT IL11RA 1.95E-01 0.44 0.53
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00872157) BMTP-11 in Patients With Castrate-Resistant Prostate Cancer With Bone Mets. U.S. National Institutes of Health.
2 Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clin Cancer Res. 2015 Jul 1;21(13):3041-51.