Details of the Drug

General Information of Drug (ID: DMBUI2A)

Drug Name
BETULINIC ACID
Synonyms
betulinic acid; 472-15-1; Mairin; Betulic acid; NSC 113090; CCRIS 6748; 3-Hydroxylup-20(29)-en-28-oic acid; UNII-4G6A18707N; 3beta-Hydroxy-20(29)-lupaene-28-oic acid; EINECS 207-448-8; NSC677578; als-357; NSC 677578; CHEMBL269277; CHEBI:3087; 3beta-Hydroxy-lup-20(29)-en-28-oic acid; 4G6A18707N; Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-; AK-72848; Lupatic Acid; SMR000445624
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 456.7
Logarithm of the Partition Coefficient (xlogp) 8.2
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C30H48O3
IUPAC Name
(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
Canonical SMILES
CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C(=O)O
InChI
InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChIKey
QGJZLNKBHJESQX-FZFNOLFKSA-N
Cross-matching ID
PubChem CID
64971
ChEBI ID
CHEBI:3087
CAS Number
472-15-1
UNII
4G6A18707N
DrugBank ID
DB12480
TTD ID
D0R9YR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30) TTIU7X1 DPOL_HHV11 Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [4]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Gene/Protein Processing [5]
Carbonic anhydrase 9 (CA9) OTNA51XT CAH9_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [7]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [6]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [3]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Gene/Protein Processing [9]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 7.6854 8.9216 5.6394 0.1975
JK1 CTRP2 8.1529 10.8132 5.1035 1.3026
JM1 CTRP2 7.8782 9.566 5.4774 0.4498
EoL-1 CTRP2 0.8723 4.0861 0.7895 34.7251
HH [Human lymphoma] CTRP2 2.5019 3.8649 2.4978 23.6146
EB1 CTRP2 2.606 3.8273 2.6038 22.9145
HD-MY-Z CTRP2 2.6714 3.7254 2.6706 22.474
Daudi CTRP2 2.7465 3.9094 2.7445 21.9777
Pfeiffer CTRP2 2.7684 3.9071 2.7665 21.8315
AML-193 CTRP2 3.0254 4.3826 3.0162 20.1436
OPM-2 CTRP2 4.0217 5.5339 3.9525 13.7117
SET-2 CTRP2 4.2835 5.4311 4.2488 11.849
697 CTRP2 5.3676 9.1861 3.8792 10.4945
DoHH2 CTRP2 5.5484 6.8371 3.6571 0.3577
JVM-2 CTRP2 5.8734 8.487 3.1373 1.8329
Jurkat CTRP2 6.1475 7.7025 3.5779 0.2873
OCI-AML-3 CTRP2 6.208 7.3575 5.5187 1.9133
HEL CTRP2 6.2592 7.566 3.6676 0.1167
DB CTRP2 6.6372 10.8495 4.1162 7.0264
Ci-1 CTRP2 6.7398 7.7085 5.6955 0.5513
KM-H2 CTRP2 6.7663 9.5117 4.03 2.0048
DEL CTRP2 6.9269 9.0494 5.1983 2.1705
NU-DUL-1 CTRP2 6.9935 9.0495 5.2399 1.9288
Ku812 CTRP2 7.0551 9.3042 5.16 2.1595
MC116 CTRP2 7.0565 7.9005 5.7646 0.1772
KE-37 CTRP2 7.0916 8.3491 5.6036 0.5673
MV4-11 CTRP2 7.1547 9.2857 5.2289 1.7854
Mono-Mac-1 CTRP2 7.1575 10.0256 4.8874 3.0876
TF-1 CTRP2 7.2213 9.13 5.3368 1.3285
Mino CTRP2 7.2801 8.407 5.6663 0.2941
KMS-12-BM CTRP2 7.3164 9.2987 5.3151 1.313
A3/Kawakami CTRP2 7.3213 8.432 5.6742 0.2592
NCI-H929 CTRP2 7.3417 9.0859 5.4203 0.9424
KMS-27 CTRP2 7.3431 9.3777 5.2951 1.3568
MOLT-3 CTRP2 7.3545 8.4627 5.6764 0.2413
KMS-26 CTRP2 7.3933 8.399 5.7153 0.156
NB4 CTRP2 7.4195 8.9693 5.507 0.6253
JURL-MK1 CTRP2 7.4622 9.4497 5.3277 1.1416
KO52 CTRP2 7.4677 9.8159 5.1711 1.6681
HEL 92.1.7 CTRP2 7.4836 8.5904 5.681 0.1874
Hs 611.T CTRP2 7.4879 11.4796 4.4151 4.5107
P12-Ichikawa CTRP2 7.5019 8.7109 5.6439 0.2506
SU-DHL-10 CTRP2 7.5026 8.3606 5.7691 0.0614
HDLM-2 CTRP2 7.5095 9.7665 5.2159 1.4731
OCI-AML-5 CTRP2 7.5496 8.5713 5.7131 0.1193
SIG-M5 CTRP2 7.5895 8.7678 5.6579 0.1948
SUP-T1 CTRP2 7.5912 9.6227 5.3206 1.0595
Reh CTRP2 7.5921 9.8285 5.2333 1.3405
MJ CTRP2 7.6166 10.1346 5.1132 1.7258
SU-DHL-4 CTRP2 7.62 8.9117 5.6171 0.2597
SUP-M2 CTRP2 7.6202 8.6631 5.7069 0.1123
Karpas-422 CTRP2 7.6215 8.8912 5.6253 0.2434
WSU-DLCL2 CTRP2 7.6259 8.7912 5.6635 0.1748
SU-DHL-1 CTRP2 7.6436 8.7888 5.6712 0.1578
NOMO-1 CTRP2 7.6462 9.0366 5.5811 0.3227
MOLP-8 CTRP2 7.6697 9.6722 5.3391 0.9433
OCI-M1 CTRP2 7.6739 8.7692 5.6894 0.1241
Raji CTRP2 7.6788 9.0469 5.5906 0.2901
P31/FUJ CTRP2 7.69 8.878 5.6569 0.1677
LAMA-84 CTRP2 7.7166 9.9036 5.2658 1.1333
OCI-Ly3 CTRP2 7.7465 9.5671 5.4186 0.6658
SEM CTRP2 7.7472 8.9065 5.6683 0.1367
HL-60 CTRP2 7.7753 8.946 5.6648 0.1352
CML-T1 CTRP2 7.7828 9.2737 5.5484 0.3359
KMS-34 CTRP2 7.8069 8.9901 5.661 0.1334
Karpas-620 CTRP2 7.8114 9.2861 5.5555 0.3104
SU-DHL-8 CTRP2 7.8125 9.3096 5.5472 0.3267
HT CTRP2 7.8235 8.9321 5.6873 0.0975
RL CTRP2 7.8245 10.6484 5.002 1.9128
KCL-22 CTRP2 7.8246 9.8068 5.3584 0.7823
AMO1 CTRP2 7.8371 8.9435 5.6883 0.0941
OCI-AML-2 CTRP2 7.8371 8.8455 5.7217 0.0609
BL-70 CTRP2 7.8391 8.9223 5.6963 0.085
KYO-1 CTRP2 7.848 9.2056 5.5997 0.2165
SKM-1 CTRP2 7.8727 9.1044 5.6452 0.1404
L-363 CTRP2 7.8812 9.184 5.6202 0.1744
Kasumi-2 CTRP2 7.9045 9.3665 5.5632 0.2628
KMM-1 CTRP2 7.9055 11.1139 4.8412 2.3979
MOLT-16 CTRP2 7.9151 9.2603 5.6058 0.1877
MOLM-13 CTRP2 7.9632 9.4731 5.5473 0.2723
BV-173 CTRP2 7.9905 9.8809 5.4044 0.5678
SU-DHL-6 CTRP2 8.0212 9.2625 5.6443 0.1121
KE-97 CTRP2 8.0229 9.63 5.5133 0.3154
MM1.S CTRP2 8.0266 9.2998 5.6334 0.1242
M-07e CTRP2 8.0407 9.5076 5.5651 0.2182
PF-382 CTRP2 8.0503 9.9901 5.3881 0.5772
OCI-Ly19 CTRP2 8.052 9.7469 5.4817 0.3672
MOTN-1 CTRP2 8.0707 9.514 5.5742 0.1957
SUP-T11 CTRP2 8.0843 9.4477 5.6028 0.1516
MOLM-16 CTRP2 8.0986 9.535 5.5773 0.1842
KMS-20 CTRP2 8.1239 9.387 5.6383 0.1015
NU-DHL-1 CTRP2 8.1374 9.8068 5.494 0.3123
HPB-ALL CTRP2 8.14 11.8656 4.6391 2.8809
PL21 CTRP2 8.1627 9.7936 5.5088 0.2771
L-1236 CTRP2 8.174 10.3834 5.2887 0.7609
EM-2 CTRP2 8.1745 16.3495 2.541 10.8415
Kasumi-1 CTRP2 8.1966 9.7633 5.533 0.2266
RPMI-8402 CTRP2 8.2027 9.7315 5.5466 0.2039
A4/Fukuda CTRP2 8.2077 9.7116 5.5556 0.1894
Ri-1 CTRP2 8.2232 11.9333 4.6563 2.7341
CA46 CTRP2 8.2551 9.8728 5.516 0.2377
EHEB CTRP2 8.2576 9.9383 5.4933 0.2748
SK-MM-2 CTRP2 8.2609 9.8109 5.5403 0.1987
JeKo-1 CTRP2 8.2637 9.5499 5.6321 0.087
U-937 CTRP2 8.2643 9.6262 5.6062 0.1134
LP-1 CTRP2 8.2709 9.6077 5.6149 0.103
L-428 CTRP2 8.2793 9.8971 5.5166 0.2302
ME1 CTRP2 8.2841 9.8429 5.5377 0.1969
RPMI-6666 CTRP2 8.3018 11.42 4.923 1.7536
Karpas-299 CTRP2 8.3203 9.7769 5.5743 0.1404
KMS-18 CTRP2 8.3267 10.0756 5.4703 0.2933
EJM CTRP2 8.3313 9.987 5.5042 0.2358
THP-1 CTRP2 8.3351 9.9839 5.5067 0.2307
MOLM-6 CTRP2 8.337 10.1332 5.4534 0.3201
L-540 CTRP2 8.3481 9.5965 5.6457 0.0651
Peer CTRP2 8.3617 9.6523 5.6316 0.075
ST486 CTRP2 8.3742 9.8008 5.5854 0.118
Granta-519 CTRP2 8.3799 9.9796 5.5252 0.1922
OCI-Ly10 CTRP2 8.3807 10.267 5.4216 0.3644
HuT 78 CTRP2 8.3817 10.4805 5.3418 0.5283
RCH-ACV CTRP2 8.385 10.0102 5.5162 0.2039
SR CTRP2 8.393 9.69 5.6297 0.0729
MOLT-13 CTRP2 8.3997 9.9439 5.5451 0.1612
P3HR-1 CTRP2 8.4013 9.9428 5.546 0.1597
KMS-21-BM CTRP2 8.4066 9.7883 5.6012 0.0968
SUP-B15 CTRP2 8.4112 9.8896 5.5681 0.1311
REC-1 CTRP2 8.4468 10.2431 5.4563 0.281
JJN-3 CTRP2 8.4535 9.7568 5.6282 0.0675
CMK CTRP2 8.4683 9.6217 5.6779 0.0344
SUP-HD1 CTRP2 8.4707 10.3294 5.4344 0.3113
NALM-6 CTRP2 8.4898 10.0529 5.54 0.1499
Namalwa CTRP2 8.5104 9.8007 5.6329 0.0583
MOLP-2 CTRP2 8.5262 10.357 5.4459 0.2754
NCO2 CTRP2 8.534 10.3703 5.4441 0.2761
KMS-11 CTRP2 8.5346 10.3509 5.4513 0.2643
DND-41 CTRP2 8.5632 10.0834 5.5558 0.1194
K-562 CTRP2 8.571 10.1451 5.5374 0.1383
RS4;11 CTRP2 8.6252 10.2 5.5379 0.1286
F-36P CTRP2 8.6519 10.4439 5.4626 0.2177
RPMI-8226 CTRP2 8.6925 10.1002 5.5952 0.0679
U266B1 CTRP2 8.7163 10.1594 5.5835 0.0743
MHH-CALL-4 CTRP2 8.7217 10.7078 5.3948 0.3037
GDM-1 CTRP2 8.8879 10.7501 5.4423 0.1937
MHH-CALL-3 CTRP2 9.0319 10.9739 5.4168 0.1971
TALL-1 [Human adult T-ALL] CTRP2 9.1917 11.3423 5.3465 0.2566
Mono-Mac-6 CTRP2 9.2183 11.651 5.2459 0.408
Ki-JK CTRP2 10.437 28.4532 -1.7437 20.2699
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 8.4183 10.3483 5.4066 0.3797
TE8 CTRP2 8.9066 10.4993 5.535 0.0922
KYSE-410 CTRP2 3.6927 5.7156 3.5596 16.1268
TE-5 CTRP2 4.5099 5.8726 4.4134 10.557
TE-6 CTRP2 7.5381 9.3646 4.4478 0.2883
KYSE-30 CTRP2 8.0966 9.0447 5.7434 0.0246
KYSE-450 CTRP2 8.2104 9.55 5.6131 0.1147
KYSE-150 CTRP2 8.2356 10.4122 5.3049 0.6857
OE33 CTRP2 8.2913 10.2633 5.3863 0.4701
TE-4 CTRP2 8.3267 10.0726 5.4714 0.2913
EC-GI-10 CTRP2 8.3948 9.8941 5.5606 0.1429
TE-9 CTRP2 8.3981 9.7188 5.6218 0.079
KYSE-180 CTRP2 8.4173 9.9334 5.5551 0.1453
KYSE-70 CTRP2 8.4574 9.951 5.5635 0.1283
TE-10 CTRP2 8.5871 10.3053 5.4874 0.1979
TE-14 CTRP2 8.5958 10.1559 5.5425 0.1284
TE-1 CTRP2 8.6092 10.3947 5.464 0.2257
TE-11 CTRP2 8.6655 10.4738 5.4571 0.2223
KYSE-510 CTRP2 8.6723 10.2952 5.522 0.1383
COLO 680N CTRP2 8.7061 10.2009 5.5661 0.0897
KYSE-140 CTRP2 9.1489 11.0565 5.4305 0.1597
OE19 CTRP2 13.4062 27.0784 0.8446 9.9549
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 15.0498 36.8293 -2.6464 16.7564
SU.86.86 CTRP2 4.2769 5.7637 4.1843 12.0944
SNU-213 CTRP2 7.1623 8.739 5.4752 0.9136
QGP-1 CTRP2 7.4123 39.32 -9.4677 35.4769
PaTu 8988t CTRP2 7.5258 9.0455 5.5255 0.5118
Panc 08.13 CTRP2 7.5811 16.8496 1.8629 14.2735
KP-4 CTRP2 7.6268 9.2183 5.5027 0.5145
L3.3 CTRP2 7.7096 9.001 5.6199 0.2239
DAN-G CTRP2 7.7407 15.0766 2.8521 10.3283
PaTu 8902 CTRP2 7.8638 9.0979 5.6442 0.1439
HuP-T4 CTRP2 7.8919 10.1261 5.2602 1.0201
MIA PaCa-2 CTRP2 7.9404 9.5477 5.5105 0.3518
TCC-Pan2 CTRP2 7.9601 9.6028 5.4979 0.37
HPAC CTRP2 8.0129 9.5495 5.539 0.2711
HuP-T3 CTRP2 8.038 10.2252 5.2894 0.8396
Panc 05.04 CTRP2 8.0694 9.4995 5.5789 0.189
SNU-410 CTRP2 8.1136 10.026 5.4016 0.5145
Panc 03.27 CTRP2 8.1249 9.688 5.5325 0.2478
YAPC CTRP2 8.131 9.3785 5.6437 0.0947
Hs 766T CTRP2 8.2091 10.1818 5.3827 0.5138
Panc 02.03 CTRP2 8.2212 9.4961 5.6354 0.0897
KP-2 CTRP2 8.2238 9.4087 5.6659 0.0626
Panc 10.05 CTRP2 8.3459 9.9499 5.523 0.2035
Capan-1 CTRP2 8.422 10.2583 5.4412 0.3146
CFPAC-1 CTRP2 8.4471 10.2074 5.4694 0.2596
PK-45H CTRP2 8.4533 10.2028 5.4734 0.2514
SUIT-2 CTRP2 8.489 9.6594 5.6725 0.0359
Capan-2 CTRP2 8.5262 10.402 5.4296 0.3026
KP-3 CTRP2 8.565 11.3025 5.101 1.031
BxPC-3 CTRP2 8.6391 11.0127 5.2478 0.6238
Panc 04.03 CTRP2 8.6613 10.4455 5.4656 0.2113
SW1990 CTRP2 8.7872 10.4235 5.5189 0.1232
PK-59 CTRP2 8.8102 10.48 5.5077 0.1313
AsPC-1 CTRP2 8.9278 10.6316 5.4976 0.1239
PaTu 8988s CTRP2 9.8139 20.4909 1.6695 11.5875
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 8.9237 18.5274 2.009 11.6623
WM266-4 CTRP2 -1.0261 1.2956 -1.0287 47.1094
WM115 CTRP2 2.341 3.6938 2.338 24.6827
MeWo CTRP2 2.571 3.0619 2.571 23.1402
HT-144 CTRP2 2.6717 6.9003 2.0989 24.4888
WT2-iPS CTRP2 2.7934 5.2118 2.6842 22.031
UACC-62 CTRP2 3.5238 8.0195 2.5834 20.2516
SK-MEL-2 CTRP2 6.9547 9.0748 5.204 2.1136
SK-MEL-28 CTRP2 7.1404 8.1429 5.7079 0.2634
WM88 CTRP2 7.1733 9.5177 5.134 2.1182
Hs 688(A).T CTRP2 7.2407 8.293 5.6931 0.2523
Hs 839.T CTRP2 7.4789 8.596 5.6771 0.1958
IGR-37 CTRP2 7.535 8.6348 5.6849 0.1655
A2058 CTRP2 7.5722 8.9961 5.5653 0.3904
A101D CTRP2 7.5745 9.6528 5.2993 1.1402
Hs 936.T CTRP2 7.7048 8.8594 5.6691 0.1455
IGR-39 CTRP2 7.8082 8.8721 5.7025 0.0834
HMCB CTRP2 7.8143 8.8786 5.7024 0.0825
IPC-298 CTRP2 7.825 8.9383 5.6857 0.0991
SK-MEL-1 CTRP2 7.8262 9.0543 5.6456 0.1506
RPMI-7951 CTRP2 7.8426 9.19 5.6032 0.212
COLO 800 CTRP2 7.8475 9.2194 5.5944 0.2255
MDA-MB-435S CTRP2 7.8575 9.2892 5.5729 0.2606
UACC-257 CTRP2 7.8844 8.9572 5.7004 0.0742
Mel JuSo CTRP2 7.8935 9.4703 5.5202 0.3504
SK-MEL-5 CTRP2 7.9078 9.0425 5.6795 0.092
RVH-421 CTRP2 7.9458 9.3451 5.5871 0.2091
CJM [Human melanoma] CTRP2 7.9573 8.9842 5.7166 0.0515
Mel Ho CTRP2 7.99 9.4597 5.5627 0.2367
Hs 294T CTRP2 8.0532 9.1969 5.6782 0.0723
LOX-IMVI CTRP2 8.0654 9.383 5.6185 0.1351
SK-MEL-30 CTRP2 8.067 9.2054 5.6801 0.0689
G-361 CTRP2 8.099 9.8948 5.4454 0.4239
IGR-1 CTRP2 8.1191 9.6581 5.541 0.2352
COLO 829 CTRP2 8.1539 13.4267 3.9284 5.5389
Hs 944.T CTRP2 8.1699 9.8004 5.5092 0.2741
WM1799 CTRP2 8.1999 9.368 5.6713 0.0609
K029AX CTRP2 8.2142 9.4967 5.6327 0.0934
A-375 CTRP2 8.2738 9.7509 5.5663 0.1596
Hs 940.T CTRP2 8.2904 9.7828 5.5613 0.1628
WM793 CTRP2 8.3068 9.6052 5.6284 0.0847
Hs 895.T CTRP2 8.3078 9.4751 5.6724 0.0496
Hs 852.T CTRP2 8.3142 10.0415 5.4779 0.284
SK-MEL-3 CTRP2 8.3375 10.0297 5.4912 0.2548
SK-MEL-31 CTRP2 8.3713 9.8142 5.5798 0.1247
COLO 792 CTRP2 8.6188 10.4347 5.4534 0.2391
WM983B CTRP2 8.9633 10.762 5.4655 0.1521
SK-MEL-24 CTRP2 9.371 17.0326 3.0133 7.4488
COLO 741 CTRP2 10.415 37.7063 -6.3081 28.2948
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 8.1911 10.1077 5.4033 0.476
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YN CTRP2 7.1497 9.423 5.1632 2.0359
IMR-32 CTRP2 7.2186 8.5412 5.5858 0.5331
Kelly CTRP2 7.4833 9.3262 5.3908 0.9242
SK-N-AS CTRP2 7.623 8.8539 5.6396 0.2165
SK-N-DZ CTRP2 7.7233 9.035 5.613 0.232
MHH-NB-11 CTRP2 7.8783 9.524 5.4935 0.4136
NH-6 CTRP2 7.9187 9.7393 5.428 0.5469
NB1 CTRP2 7.9524 9.6391 5.481 0.4092
CHP-212 CTRP2 8.1283 9.9951 5.4197 0.4672
SK-N-FI CTRP2 8.1895 9.5623 5.6013 0.1322
CHP-126 CTRP2 8.2603 9.7262 5.57 0.1577
KP-N-SI9s CTRP2 8.3243 9.522 5.6624 0.055
SK-N-BE(2) CTRP2 8.7492 10.4874 5.4832 0.1698
SK-N-SH CTRP2 8.8724 10.6991 5.4544 0.1815
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 7.7878 9.3591 5.5182 0.3989
HuH-28 CTRP2 7.8651 9.3423 5.5563 0.2891
SNU-308 CTRP2 8.0866 9.4405 5.6062 0.1466
SNU-478 CTRP2 8.1412 10.0482 5.4049 0.4945
SNU-1196 CTRP2 8.2146 9.5141 5.627 0.0992
SNU-1079 CTRP2 8.2352 9.9862 5.4669 0.3293
SNU-869 CTRP2 8.67 10.3587 5.4992 0.1654
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 5.3767 6.3584 5.2111 5.0506
Hs 822.T CTRP2 7.5825 16.5785 1.9978 13.7867
SJSA-1 CTRP2 7.6677 9.5769 5.3775 0.8311
TC71 CTRP2 7.8215 9.568 5.4521 0.5379
SK-N-MC CTRP2 7.8527 8.6883 5.7792 0.0217
SW1353 CTRP2 8.0901 10.8261 5.0663 1.4669
HOS CTRP2 8.1012 9.4426 5.6108 0.1377
Hs 888.T CTRP2 8.2081 10.989 5.0575 1.4024
SaOS-2 CTRP2 8.258 10.1401 5.419 0.4151
SK-ES-1 CTRP2 8.4247 10.0122 5.5303 0.1753
MG-63 CTRP2 8.5186 9.8691 5.6129 0.0725
CAL-78 CTRP2 8.6054 10.2477 5.5143 0.1593
MHH-ES-1 CTRP2 8.852 10.5555 5.4967 0.1363
G-292 clone A141B1 CTRP2 8.9465 10.6941 5.4828 0.1361
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 2.6044 3.0749 2.6044 22.9178
CAL-85-1 CTRP2 4.9226 5.8257 4.8722 7.6467
KPL-1 CTRP2 5.0407 5.8881 4.9874 6.8702
HDQ-P1 CTRP2 6.6498 9.3245 4.8775 3.8527
HCC1937 CTRP2 7.283 9.9788 4.9886 2.5396
HMC-1-8 CTRP2 7.4437 8.5899 5.6653 0.2299
HCC1500 CTRP2 7.6073 10.5587 4.9183 2.4328
ZR-75-1 CTRP2 7.6644 8.8596 5.6537 0.1799
MDA-MB-361 CTRP2 7.7168 9.5298 5.4198 0.6804
CAMA-1 CTRP2 7.7702 9.4057 5.4927 0.4655
HCC1428 CTRP2 7.8515 9.0493 5.6567 0.1296
BT-20 CTRP2 8.0228 11.1092 4.9087 2.0471
CAL-148 CTRP2 8.0628 9.7666 5.4787 0.3691
JIMT-1 CTRP2 8.1246 9.2653 5.6799 0.0623
SK-BR-3 CTRP2 8.1781 9.8922 5.4788 0.3267
HCC38 CTRP2 8.2019 10.0662 5.4236 0.4279
Hs 578T CTRP2 8.2042 9.9451 5.4697 0.3348
MDA-MB-415 CTRP2 8.2099 10.2792 5.3455 0.5998
MDA-MB-453 CTRP2 8.2496 9.8846 5.5096 0.2496
MDA-MB-468 CTRP2 8.2605 9.7199 5.5723 0.1546
BT-474 CTRP2 8.272 9.4102 5.6818 0.0465
HCC1395 CTRP2 8.3614 10.0842 5.4808 0.2652
HCC1419 CTRP2 8.3659 9.7715 5.5925 0.1117
BT-549 CTRP2 8.4358 9.9776 5.5465 0.1523
HCC202 CTRP2 8.5555 10.6887 5.3356 0.4695
MDA-MB-231 CTRP2 8.5782 10.6737 5.3505 0.4308
CAL-51 CTRP2 8.6412 9.904 5.6429 0.0415
HCC2218 CTRP2 8.6499 10.3003 5.5121 0.1535
T-47D CTRP2 8.6667 10.7747 5.3487 0.4025
MDA-MB-157 CTRP2 8.7492 10.5867 5.4484 0.2153
ZR-75-30 CTRP2 8.8573 10.5247 5.5091 0.1227
AU565 CTRP2 8.9039 10.7077 5.4629 0.1654
HCC1143 CTRP2 8.9106 11.3153 5.2466 0.5129
BT 320 CTRP2 5.9202 6.4868 5.7127 1.654
BT 498 CTRP2 6.8915 10.2135 4.6167 4.5498
BT 482 CTRP2 7.0103 8.5109 5.4927 0.9901
BT 248 CTRP2 7.1051 11.8887 3.9522 6.9373
BT 239 CTRP2 7.3209 8.6814 5.577 0.4942
BT 328 CTRP2 7.3427 8.754 5.558 0.5324
BT 444 CTRP2 7.5258 8.7394 5.643 0.2436
BT 112 CTRP2 7.5307 8.7122 5.655 0.219
BT 330 CTRP2 7.5326 8.7617 5.6374 0.2519
BT 286 CTRP2 7.5452 9.4949 5.3511 0.9998
BT164 CTRP2 7.5496 8.4945 5.7399 0.0852
BT 179 CTRP2 7.6016 8.5812 5.7286 0.089
BT 422 CTRP2 7.6034 8.7023 5.6868 0.1444
BT 228 CTRP2 7.6098 8.7968 5.6552 0.1933
BT 131 CTRP2 7.6213 8.9487 5.6038 0.2856
BT 340 CTRP2 7.6508 8.6624 5.7183 0.0922
BT 139 CTRP2 7.6759 8.7028 5.7134 0.0935
BT 271 CTRP2 7.7688 9.1628 5.584 0.2701
BT147 CTRP2 7.7948 9.399 5.5058 0.4234
BT 416 CTRP2 7.8704 9.1945 5.6123 0.1894
BT 224 CTRP2 7.8972 9.1036 5.6545 0.1231
BT 504 CTRP2 7.9226 9.058 5.6794 0.0897
BT 187 CTRP2 7.9615 10.0388 5.3288 0.7789
BT 216 CTRP2 7.9795 9.5016 5.5434 0.2742
BT 359 CTRP2 8.0767 9.3677 5.628 0.1213
BT 440 CTRP2 8.1008 9.4956 5.592 0.1626
BT 333 CTRP2 8.1384 9.3603 5.6525 0.0848
BT 245 CTRP2 8.1849 9.785 5.5206 0.2501
BT 428 CTRP2 8.2571 9.8309 5.5318 0.2125
BT 159 CTRP2 8.3275 9.4752 5.6791 0.0437
BT 232 CTRP2 8.3603 9.9697 5.5214 0.2024
BT 145 CTRP2 8.369 9.5946 5.6535 0.0571
BT 231 CTRP2 8.9097 10.9575 5.3771 0.2805
BT 172 CTRP2 11.0702 25.2487 0.2385 14.3528
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.9595 8.8613 5.758 0.0256
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF268 CTRP2 2.8297 4.3519 2.8164 21.4614
SF539 CTRP2 2.8424 8.3664 1.725 25.3123
KNS-60 CTRP2 3.5038 4.7093 3.4932 16.9615
U-251MG CTRP2 3.7637 4.4823 3.7631 15.1964
CAS-1 CTRP2 4.4804 5.0087 4.4797 10.4218
Hs 683 CTRP2 5.3895 5.9687 5.3488 4.5036
SNU-466 CTRP2 7.3861 8.5134 5.6704 0.2413
LN-18 CTRP2 7.4474 8.3835 5.7412 0.1035
KNS-81 CTRP2 7.5142 8.3539 5.7755 0.0538
TM-31 CTRP2 7.573 8.6987 5.6765 0.1685
CCF-STTG1 CTRP2 7.5896 8.6961 5.6837 0.1525
GMS-10 CTRP2 7.6509 8.795 5.6717 0.1551
SF295 CTRP2 7.7145 8.8809 5.6651 0.149
YKG-1 CTRP2 7.7264 9.2026 5.5518 0.3519
NMC-G1 CTRP2 7.7507 9.1894 5.5668 0.3108
KG-1-C CTRP2 7.7638 9.05 5.6233 0.2015
U-118MG CTRP2 7.7668 13.0059 3.8733 6.2735
DK-MG CTRP2 7.7796 9.0278 5.6374 0.1743
KALS-1 CTRP2 7.85 13.0582 3.9041 6.037
U-87MG ATCC CTRP2 8.0212 9.4898 5.5639 0.2256
Becker CTRP2 8.0344 9.4565 5.581 0.1947
SNU-626 CTRP2 8.0447 9.3656 5.617 0.1412
T98G CTRP2 8.0707 10.4808 5.2008 1.0699
D283 Med CTRP2 8.122 9.5173 5.5923 0.1575
GB-1 CTRP2 8.1533 9.5125 5.6054 0.1341
SNU-201 CTRP2 8.1747 9.2981 5.6861 0.0524
KNS-42 CTRP2 8.2049 9.7725 5.5328 0.2246
Daoy CTRP2 8.2441 9.897 5.503 0.2622
YH-13 CTRP2 8.2651 9.867 5.5219 0.2256
DBTRG-05MG CTRP2 8.2752 9.8302 5.5389 0.1975
M059K CTRP2 8.285 9.6466 5.6066 0.1096
SNU-489 CTRP2 8.31 9.6173 5.6254 0.087
8-MG-BA CTRP2 8.3213 9.7188 5.5947 0.1165
42-MG-BA CTRP2 8.3898 9.7164 5.6197 0.0818
GaMG CTRP2 8.4246 9.6955 5.6388 0.0624
A-172 CTRP2 8.4254 10.2373 5.4501 0.298
SW1783 CTRP2 8.4553 11.9562 4.7735 2.1125
LN-229 CTRP2 8.5673 10.0281 5.5761 0.0985
SW1088 CTRP2 8.5862 10.3189 5.4823 0.2051
SF126 CTRP2 8.6864 10.1679 5.5704 0.0884
GOS-3 CTRP2 8.6913 10.144 5.5801 0.0797
ONS-76 CTRP2 8.8101 10.2996 5.5688 0.0757
SNB-75 CTRP2 8.9819 10.879 5.4317 0.1884
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFE-184 CTRP2 2.5574 3.1065 2.5574 23.2308
HEC-151 CTRP2 4.6678 6.8641 4.2594 10.6696
JHUEM-1 CTRP2 4.7538 5.3229 4.7502 8.6101
HEC-265 CTRP2 6.7858 9.3425 4.9649 3.2907
RL95-2 CTRP2 7.5748 9.1888 5.4909 0.5741
KLE CTRP2 7.6768 10.3571 5.0485 1.8932
EN CTRP2 7.715 9.281 5.517 0.435
HEC-108 CTRP2 7.764 8.7635 5.7239 0.0684
HEC-6 CTRP2 8.0354 9.2197 5.6641 0.0882
HEC-1-B CTRP2 8.0538 9.7146 5.4944 0.341
JHUEM-2 CTRP2 8.2725 9.9638 5.4898 0.2762
ESS-1 CTRP2 8.3271 9.5808 5.6437 0.0689
HEC-59 CTRP2 8.3296 9.5537 5.6536 0.0609
MFE-319 CTRP2 8.3423 9.6308 5.6321 0.0769
JHUEM-3 CTRP2 8.367 10.1689 5.4522 0.3126
AN3-CA CTRP2 8.4741 10.1063 5.5155 0.1844
HEC-50B CTRP2 8.5111 10.261 5.4746 0.2344
HEC-251 CTRP2 8.6141 10.1691 5.5445 0.1233
HEC-1-A CTRP2 8.7862 10.6344 5.4453 0.2112
MFE-296 CTRP2 9.1408 10.9721 5.4566 0.1336
Ishikawa (Heraklio) 02 ER- CTRP2 7.8336 8.5197 5.8274 0.0067
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCZ CTRP2 4.1263 5.1458 4.1116 12.828
TUHR10TKB CTRP2 4.5084 30.088 -7.2802 37.8476
TUHR4TKB CTRP2 7.4585 8.6851 5.6357 0.2843
UO-31 CTRP2 7.5564 11.2072 4.588 3.7439
A-498 CTRP2 7.614 8.9128 5.6143 0.2674
BFTC-909 CTRP2 7.7765 9.214 5.5681 0.2982
Caki-2 CTRP2 7.9175 9.2104 5.6245 0.1592
RCC10RGB CTRP2 8.0391 9.461 5.5811 0.1933
KMRC-2 CTRP2 8.139 9.5373 5.5915 0.1549
TUHR14TKB CTRP2 8.1901 26.1882 -2.2999 33.6571
CAL-54 CTRP2 8.2103 9.9593 5.4669 0.338
OS-RC-2 CTRP2 8.3376 9.7607 5.5861 0.1233
KMRC-1 CTRP2 8.3452 9.6157 5.6382 0.0714
VMRC-RCW CTRP2 8.4283 10.1032 5.4995 0.2179
SNU-1272 CTRP2 8.4346 12.3547 4.5882 2.7643
ACHN CTRP2 8.586 9.93 5.6156 0.0634
KMRC-20 CTRP2 8.6018 10.1232 5.5559 0.1134
786-O CTRP2 8.7963 10.5596 5.4752 0.1706
Caki-1 CTRP2 9.2713 11.1732 5.4341 0.137
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-CO-1 CTRP2 7.0761 16.5571 1.6211 16.0044
HCC-56 CTRP2 7.2255 8.1855 5.7271 0.1887
C2BBe1 CTRP2 7.2482 9.8537 5.025 2.4428
SNU-C5 CTRP2 7.2597 9.5064 5.1907 1.8117
SNU-61 CTRP2 7.2883 10.2908 4.8467 3.0786
SNU-C1 CTRP2 7.3795 12.0357 4.0752 6.0212
COLO205 CTRP2 7.4458 8.5437 5.6831 0.1957
DLD-1 CTRP2 7.4923 8.4663 5.7288 0.1105
OUMS-23 CTRP2 7.5385 8.6681 5.6741 0.1824
SNU-C4 CTRP2 7.6572 8.7811 5.679 0.1426
SNU-175 CTRP2 7.6835 9.4157 5.4501 0.6189
LS411N CTRP2 7.7522 9.0136 5.632 0.1905
NCI-H508 CTRP2 7.7592 13.0323 3.8556 6.3545
HT-29 CTRP2 7.7979 9.1446 5.6022 0.2272
CW-2 CTRP2 7.9826 10.2622 5.2481 0.9925
SW948 CTRP2 7.9979 9.426 5.578 0.2092
HCT 15 CTRP2 8.0046 9.9038 5.4016 0.5674
LS123 CTRP2 8.0123 9.4255 5.5837 0.1964
SW48 CTRP2 8.0675 9.7678 5.4802 0.3642
SW1417 CTRP2 8.0772 9.637 5.5324 0.2624
LS180 CTRP2 8.1185 9.5552 5.5776 0.1789
HCT 8 CTRP2 8.1407 9.2491 5.6908 0.0523
CCK-81 CTRP2 8.1423 10.3801 5.2755 0.814
SNU-503 CTRP2 8.1464 9.8135 5.4951 0.3071
LS513 CTRP2 8.1496 9.665 5.5502 0.2122
HT-55 CTRP2 8.1623 9.3886 5.6513 0.0827
HCT 116 CTRP2 8.1789 9.4312 5.6426 0.0887
SW620 CTRP2 8.2531 9.971 5.4796 0.3001
LS1034 CTRP2 8.2729 9.8829 5.5192 0.2278
COLO201 CTRP2 8.2892 9.5381 5.645 0.0723
NCI-H747 CTRP2 8.2943 10.7408 5.2011 0.9236
KM12 CTRP2 8.3004 9.5562 5.6427 0.0728
MDST8 CTRP2 8.312 9.3934 5.7008 0.0325
LoVo CTRP2 8.3292 10.1867 5.4305 0.3654
T84 CTRP2 8.3516 10.3725 5.3702 0.4795
NCI-H716 CTRP2 8.3521 9.9933 5.5098 0.2215
HT115 CTRP2 8.3671 9.5745 5.6595 0.0531
COLO 320 CTRP2 8.381 11.1184 5.0888 1.1837
RCM-1 [Human ESC] CTRP2 8.422 9.7026 5.6355 0.0651
COLO 678 CTRP2 8.5587 10.2839 5.4844 0.2085
CL-11 CTRP2 8.6911 10.4607 5.4712 0.197
GP2d CTRP2 8.6929 10.4218 5.4855 0.178
RKO CTRP2 8.8042 10.3382 5.5538 0.0884
SNU-407 CTRP2 9.1527 10.598 5.5856 0.0387
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-5 CTRP2 2.6331 5.093 2.5315 23.0726
SNU-761 CTRP2 4.4091 6.4361 3.7675 7.2145
Hep 3B2.1-7 CTRP2 5.2834 6.5855 2.6355 0.1131
SNU-886 CTRP2 6.5552 22.5779 -1.8007 26.5395
JHH-6 CTRP2 7.3312 8.2739 5.7365 0.1389
SNU-475 CTRP2 7.6937 9.0084 5.6109 0.2455
SK-HEP-1 CTRP2 7.8181 8.8782 5.7039 0.0804
JHH-1 CTRP2 7.9332 9.157 5.649 0.1229
HLF CTRP2 8.0227 9.3611 5.6104 0.1547
JHH-2 CTRP2 8.177 9.7356 5.5354 0.2282
HuH-1 CTRP2 8.1955 9.486 5.6298 0.0992
SNU-398 CTRP2 8.3144 10.1893 5.4236 0.3843
PLC/PRF/5 CTRP2 8.3286 9.8333 5.5576 0.1596
HuH-6 CTRP2 8.3973 11.5308 4.9251 1.6693
SNU-423 CTRP2 8.3992 9.9549 5.541 0.1666
SNU-182 CTRP2 8.402 10.8616 5.2023 0.8566
JHH-4 CTRP2 8.5115 9.976 5.5742 0.1083
Hep-G2 CTRP2 8.5459 10.087 5.5484 0.1302
SNU-387 CTRP2 8.5952 10.2226 5.5193 0.1551
SNU-449 CTRP2 8.6513 10.4627 5.4557 0.2277
Li-7 CTRP2 8.82 10.8091 5.396 0.2747
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 136 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H810 CTRP2 2.608 3.1713 2.608 22.8938
NCI-H1666 CTRP2 2.6611 4.5364 2.6293 22.6469
HCC4006 CTRP2 2.69 3.4182 2.6899 22.3479
DV-90 CTRP2 2.8092 4.1293 2.8037 21.5719
NCI-H1573 CTRP2 3.274 8.8596 1.9664 23.2296
NCI-H1944 CTRP2 3.4533 5.1501 3.4012 17.4384
DMS 454 CTRP2 3.5978 6.0385 3.376 17.0753
NCI-H2444 CTRP2 3.7074 5.0009 3.5969 9.9558
HCC2935 CTRP2 3.9104 5.4191 3.8516 14.4168
NCI-H2087 CTRP2 3.9371 7.0756 3.399 15.9983
NCI-H522 CTRP2 4.3795 6.6104 4.0466 12.2913
NCI-H520 CTRP2 6.4408 9.5622 4.604 5.3312
NCI-H2141 CTRP2 6.5376 9.1483 4.8818 4.0132
RERF-LC-Ad1 CTRP2 6.6637 9.5298 4.787 4.2033
ChaGo-K-1 CTRP2 6.8389 9.9627 4.7014 4.2836
EPLC-272H CTRP2 6.9256 8.708 5.3556 1.5715
NCI-H1581 CTRP2 6.9271 8.6083 5.4019 1.398
NCI-H1092 CTRP2 7.0351 8.5341 5.496 0.9559
A-549 CTRP2 7.1196 11.1788 4.3087 5.4614
NCI-H526 CTRP2 7.1912 9.8925 4.9714 2.7174
LCLC-103H CTRP2 7.2333 8.1396 4.7575 0.0146
SBC-5 CTRP2 7.2683 8.1386 5.7609 0.1175
NCI-H1694 CTRP2 7.3105 8.9786 5.4497 0.8743
LCLC-97TM1 CTRP2 7.3195 13.7315 3.2048 9.6157
LK2 CTRP2 7.3321 8.1809 5.7698 0.0902
MOR/CPR CTRP2 7.4165 8.2237 5.7854 0.0577
NCI-H524 CTRP2 7.4506 10.1084 5.0303 2.1925
HCC95 CTRP2 7.4712 9.6969 5.2254 1.4762
HCC44 CTRP2 7.4777 9.7332 5.2131 1.5125
LOU-NH91 CTRP2 7.5111 9.129 5.4854 0.6274
BEN CTRP2 7.5786 8.497 5.7494 0.0701
HCC15 CTRP2 7.5945 11.0388 4.6904 3.3026
LC-1/sq-SF CTRP2 7.667 8.7607 5.6899 0.1249
DMS 79 CTRP2 7.6776 9.4297 5.4419 0.6444
Lu-99 CTRP2 7.7048 9.0776 5.5898 0.2821
NCI-H2106 CTRP2 7.7169 9.955 5.2442 1.2009
NCI-H1341 CTRP2 7.7235 9.8772 5.2803 1.0827
NCI-H727 CTRP2 7.7268 9.5951 5.3982 0.7337
NCI-H650 CTRP2 7.7668 9.7184 4.4083 0.2891
Lu-65 CTRP2 7.7885 9.4728 5.4747 0.4995
NCI-H23 CTRP2 7.848 9.8477 5.3529 0.7828
COLO 668 CTRP2 7.8486 9.8378 5.3572 0.7707
NCI-H196 CTRP2 7.8551 10.533 5.0689 1.6569
NCI-H2171 CTRP2 7.8694 9.5801 5.4682 0.4752
NCI-H1793 CTRP2 7.8699 9.5746 5.4706 0.4695
NCI-H460 CTRP2 7.8981 9.003 5.6896 0.0829
NCI-H841 CTRP2 7.8993 14.6894 3.1532 8.9176
NCI-H2291 CTRP2 7.9174 9.8083 5.4004 0.6161
NCI-H2030 CTRP2 7.9351 9.6959 5.4519 0.482
NCI-H1563 CTRP2 7.9352 9.5912 5.4919 0.3928
NCI-H2122 CTRP2 7.9396 9.1307 5.6605 0.1078
Calu-1 CTRP2 7.943 10.071 5.3072 0.85
NCI-H1155 CTRP2 7.9522 9.323 5.5975 0.1909
NCI-H1568 CTRP2 7.9656 10.0106 5.342 0.7409
NCI-H1755 CTRP2 7.9683 10.2466 5.2476 1.0037
DMS 273 CTRP2 7.9761 9.5534 5.5229 0.3138
SHP-77 CTRP2 7.9899 9.2697 5.6304 0.1351
NCI-H441 CTRP2 8.0153 10.5059 5.1632 1.2226
HCC2108 CTRP2 8.0274 12.9401 4.0759 5.131
VMRC-LCD CTRP2 8.0278 9.6157 5.5206 0.3
NCI-H2126 CTRP2 8.0312 9.2171 5.6635 0.0895
NCI-H1355 CTRP2 8.0331 10.2536 5.2757 0.8807
HCC1833 CTRP2 8.0466 11.9013 4.5684 3.239
NCI-H211 CTRP2 8.0545 9.9601 5.4015 0.5429
RERF-LC-MS CTRP2 8.0732 9.654 5.5246 0.2775
LUDLU-1 CTRP2 8.0822 9.7701 5.4853 0.3485
NCI-H2081 CTRP2 8.0991 10.2241 5.3179 0.7272
IA-LM CTRP2 8.1056 9.6743 5.5299 0.258
NCI-H226 CTRP2 8.121 9.1513 5.7166 0.0371
Sq-1 CTRP2 8.1429 9.4837 5.6117 0.1285
HCC78 CTRP2 8.1626 10.0493 5.4135 0.4659
NCI-H2172 CTRP2 8.1734 9.4373 5.6386 0.0935
NCI-H2196 CTRP2 8.1762 9.7373 5.5345 0.2299
HCC1588 CTRP2 8.1854 9.5248 5.6128 0.1194
NCI-H2009 CTRP2 8.1901 9.7751 5.5262 0.2393
COR-L95 CTRP2 8.1973 9.5729 5.6005 0.1318
NCI-H2029 CTRP2 8.2 9.7093 5.5535 0.1943
RERF-LC-Ad2 CTRP2 8.2061 9.5925 5.5969 0.1345
HCC827 CTRP2 8.225 9.7161 5.5605 0.1783
NCI-H2023 CTRP2 8.2343 9.6775 5.5775 0.1533
NCI-H292 CTRP2 8.252 9.8631 5.5183 0.2349
NCI-H1703 CTRP2 8.254 9.8511 5.5234 0.2263
HCC2279 CTRP2 8.2543 10.5313 5.2664 0.7735
NCI-H2228 CTRP2 8.26 11.1515 5.0154 1.4933
KNS-62 CTRP2 8.2675 9.5852 5.6214 0.0969
NCI-H1105 CTRP2 8.2883 9.8619 5.5325 0.2036
NCI-H2405 CTRP2 8.2937 10.2173 5.4047 0.4304
NCI-H358 CTRP2 8.2958 10.3184 5.3673 0.5096
NCI-H889 CTRP2 8.3412 9.985 5.5087 0.2262
NCI-H1975 CTRP2 8.3428 9.8427 5.5596 0.1542
SK-MES-1 CTRP2 8.3437 10.3669 5.369 0.4853
NCI-H1339 CTRP2 8.3546 9.7655 5.5906 0.1156
NCI-H1435 CTRP2 8.3617 9.8442 5.5659 0.1426
NCI-H1915 CTRP2 8.3697 11.321 4.9994 1.4589
NCI-H1734 CTRP2 8.3716 10.177 5.451 0.3132
NCI-H2286 CTRP2 8.3928 16.7718 2.4893 10.7064
HCC1438 CTRP2 8.3948 9.7529 5.6091 0.0909
DMS 114 CTRP2 8.4066 9.92 5.5559 0.1464
NCI-H838 CTRP2 8.4153 9.6955 5.6356 0.0658
NCI-H1651 CTRP2 8.4266 10.0805 5.5069 0.2074
NCI-H2085 CTRP2 8.4278 10.5931 5.3184 0.5601
CAL-12T CTRP2 8.4311 10.0017 5.5364 0.166
NCI-H69 CTRP2 8.4312 10.3636 5.4061 0.376
HCC1171 CTRP2 8.4409 11.0683 5.1375 1.0074
HCC366 CTRP2 8.442 10.1537 5.4867 0.2338
NCI-H647 CTRP2 8.4505 10.3747 5.4098 0.3624
T3M-10 CTRP2 8.4788 10.1006 5.5192 0.1785
NCI-H1184 CTRP2 8.5188 10.2237 5.4907 0.2088
SK-LU-1 CTRP2 8.521 10.209 5.4968 0.1998
NCI-H1650 CTRP2 8.5477 10.1351 5.5324 0.1482
NCI-H1792 CTRP2 8.5661 10.9547 5.2387 0.6791
HOP-62 CTRP2 8.5942 19.8071 1.155 15.0503
NCI-H2342 CTRP2 8.6187 10.3808 5.4725 0.2114
DMS 53 CTRP2 8.6286 10.2003 5.539 0.1268
Calu-6 CTRP2 8.6351 10.1311 5.5649 0.0998
HCC1195 CTRP2 8.6355 13.8258 4.0424 4.5248
HARA [Human squamous cell lung carcinoma] CTRP2 8.6432 10.3255 5.501 0.1684
NCI-H1838 CTRP2 8.6443 10.4329 5.4636 0.218
NCI-H1299 CTRP2 8.6564 10.4003 5.4796 0.1932
NCI-H2170 CTRP2 8.6631 10.5041 5.4454 0.24
NCI-H661 CTRP2 8.707 10.4926 5.4659 0.2007
NCI-H1869 CTRP2 8.7187 10.4568 5.4827 0.1763
RERF-LC-A1 CTRP2 8.7487 10.1104 5.6109 0.0523
EBC-1 CTRP2 8.7505 10.5517 5.4612 0.1976
NCI-H322 CTRP2 8.7669 10.0542 5.6355 0.0373
NCI-H446 CTRP2 8.7843 10.6263 5.4475 0.2087
SW1271 CTRP2 8.9107 10.6461 5.4865 0.1379
LXF 289 CTRP2 8.9382 10.4856 5.5505 0.0765
NCI-H2110 CTRP2 9.0466 11.1018 5.3774 0.2466
EKVX CTRP2 9.1061 10.9432 5.4542 0.1412
NCI-H1373 CTRP2 9.1204 10.7027 5.5402 0.0665
HOP-92 CTRP2 9.1423 22.5512 0.2088 17.118
NCI-H1395 CTRP2 9.1543 11.3506 5.3295 0.2902
COR-L105 CTRP2 9.1797 11.0004 5.4606 0.1241
Calu-3 CTRP2 10.0531 25.1957 -0.431 17.5679
Hs 888.Lu CTRP2 8.6703 10.2907 5.5228 0.1377
⏷ Show the Full List of 136 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.1425 7.928 5.7884 0.1079
P-STS CTRP2 7.8136 9.6784 5.4049 0.6628
SYO-1 CTRP2 7.8676 9.2578 5.5883 0.2299
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 7.3049 9.0332 5.4237 0.9616
Aska-SS CTRP2 7.924 9.2272 5.6209 0.1627
HT-1080 CTRP2 1.8363 2.8585 1.8361 28.0356
A-204 CTRP2 3.7565 5.9762 3.5659 15.9071
TE 441.T CTRP2 4.7895 5.4321 4.7816 8.3869
Hs 729.T CTRP2 5.1764 5.994 5.1104 6.0121
BT-12 CTRP2 6.994 8.11 5.6546 0.4852
SW982 CTRP2 7.6566 8.8473 5.6551 0.1797
KYM-1 CTRP2 7.8039 9.2999 5.5473 0.3299
GCT CTRP2 7.8767 9.5355 5.4885 0.4255
BT-16 CTRP2 7.8948 9.2454 5.6034 0.197
SK-UT-1 CTRP2 8.0563 9.5344 5.5614 0.2198
RKN CTRP2 8.1396 9.2833 5.679 0.0614
TTC-709 CTRP2 8.1994 9.545 5.6109 0.1191
MES-SA CTRP2 8.2415 9.4305 5.6647 0.0617
Rh41 CTRP2 8.2882 9.7326 5.578 0.1419
TE 617.T CTRP2 8.2941 9.6356 5.6136 0.1009
Rh18 CTRP2 8.5136 9.9598 5.5805 0.1018
SK-LMS-1 CTRP2 8.6318 10.1092 5.5712 0.0945
RD CTRP2 8.7157 10.4722 5.4763 0.1851
G-402 CTRP2 8.7273 10.6326 5.4239 0.2561
G-401 CTRP2 9.0527 10.926 5.441 0.1643
Tm87-16 CTRP2 13.9875 35.4237 -2.67 17.9307
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.4007 8.9516 5.5053 0.6423
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.2188 9.8037 5.5269 0.2302
A2780 CTRP2 2.4622 4.5944 2.415 24.0243
TYK-nu CTRP2 2.596 3.2874 2.596 22.9737
TOV-112D CTRP2 4.3099 5.5946 4.2525 11.7513
OAW42 CTRP2 4.8279 5.5315 4.8139 8.1515
EFO-27 CTRP2 5.8642 7.6078 5.1079 4.2986
COV362 CTRP2 6.0618 7.8742 5.1439 3.7517
OV56 CTRP2 7.2682 8.1972 5.7398 0.1517
OVSAHO CTRP2 7.4611 9.7262 5.207 1.5491
OVCAR-4 CTRP2 7.8565 9.757 5.3932 0.6689
JHOM-1 CTRP2 7.9559 9.1686 5.6532 0.1134
SNU-119 CTRP2 8.0342 10.0401 5.3614 0.6517
COV434 CTRP2 8.0489 9.9843 5.3897 0.5739
JHOS-2 CTRP2 8.0765 9.4792 5.5888 0.1727
Kuramochi CTRP2 8.115 10.1012 5.3732 0.5807
SNU-8 CTRP2 8.1378 9.0176 5.7658 0.0143
OVCAR-5 CTRP2 8.155 9.5855 5.5805 0.1664
FU-OV-1 CTRP2 8.2121 10.1422 5.3991 0.4762
ONCO-DG-1 CTRP2 8.246 9.6305 5.5981 0.1256
OV7 CTRP2 8.2905 10.0742 5.4566 0.3297
SK-OV-3 CTRP2 8.294 9.8457 5.5404 0.1907
Caov-3 CTRP2 8.3057 9.7324 5.5844 0.1309
OV-90 CTRP2 8.327 9.8063 5.5665 0.1486
HEY A8 CTRP2 8.3654 9.551 5.6667 0.0484
RMG-I CTRP2 8.4609 10.4608 5.3821 0.412
OAW28 CTRP2 8.476 10.083 5.5244 0.1723
OVK18 CTRP2 8.5126 9.9054 5.5986 0.0851
OC 314 CTRP2 8.5547 9.7762 5.656 0.0403
EFO-21 CTRP2 8.6675 10.3139 5.5138 0.1484
MCAS CTRP2 8.7063 10.3133 5.5279 0.1263
SNU-840 CTRP2 8.7171 10.0829 5.6093 0.0558
OVTOKO CTRP2 8.767 10.7108 5.4111 0.2654
JHOC-5 CTRP2 8.7788 10.0784 5.6315 0.0385
IGROV-1 CTRP2 8.791 10.7942 5.3903 0.2915
OVCAR-8 CTRP2 8.7994 10.3656 5.5429 0.0985
COV644 CTRP2 8.8941 10.2543 5.6122 0.0411
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 7.3384 9.8423 5.0847 2.115
ACC-MESO-1 CTRP2 7.9171 9.2541 5.6088 0.1826
MPP 89 CTRP2 8.1915 10.3292 5.3179 0.6767
NCI-H2452 CTRP2 8.4125 10.4672 5.3598 0.4763
NCI-H2052 CTRP2 8.6106 10.2714 5.5079 0.1661
JL-1 CTRP2 8.6516 17.4811 2.3261 10.9244
IST-Mes1 CTRP2 8.7177 10.4383 5.4888 0.169
NCI-H28 CTRP2 8.8814 10.7408 5.4432 0.1939
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 CTRP2 5.5865 8.684 4.326 8.1582
NCI-H660 CTRP2 7.1056 9.0788 5.2938 1.6005
VCaP CTRP2 8.0645 9.4843 5.5825 0.1849
PaCa-3 CTRP2 8.2005 9.2335 5.7161 0.0318
LNCaP clone FGC CTRP2 8.2545 10.4028 5.317 0.6462
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 4.5594 5.838 4.4751 10.1845
YD-15 CTRP2 7.6307 8.7615 5.676 0.1537
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 2.4833 5.2229 2.3476 24.1881
HGC-27 CTRP2 3.4352 4.7922 3.4174 17.4428
MKN1 CTRP2 3.6531 4.4584 3.6521 15.9345
Hs 746.T CTRP2 4.6065 5.7045 4.5532 9.762
KE-39 CTRP2 4.9556 9.5649 3.311 13.761
OCUM-1 CTRP2 6.1038 13.7461 2.243 15.562
GSU CTRP2 6.7977 7.4068 5.8432 0.1182
NCI-N87 CTRP2 7.3481 10.471 4.8004 3.1831
MKN45 CTRP2 7.544 8.4368 5.7577 0.0667
SNU-668 CTRP2 7.671 9.1105 5.5635 0.35
ECC12 CTRP2 7.7117 8.7779 5.7003 0.1024
SNU-5 CTRP2 7.7177 9.0676 5.5987 0.2602
SNU-620 CTRP2 7.7487 8.949 5.6538 0.1573
ECC10 CTRP2 7.9186 9.4907 5.5229 0.3351
KATO III CTRP2 8.1195 9.9303 5.4406 0.4258
MKN7 CTRP2 8.1251 9.8992 5.4546 0.3941
23132/87 CTRP2 8.1285 9.3814 5.6418 0.097
NUGC-4 CTRP2 8.1433 9.8619 5.476 0.3444
LMSU CTRP2 8.195 9.709 5.5518 0.1981
SNU-1 CTRP2 8.2828 9.7818 5.5588 0.1677
AGS CTRP2 8.345 9.6526 5.6257 0.0822
GSS CTRP2 8.3511 9.7252 5.6031 0.1029
IM95 CTRP2 8.3992 10.6069 5.3009 0.6134
HuG1-N CTRP2 8.4166 10.1235 5.4878 0.2386
Fu97 CTRP2 8.4246 10.1175 5.493 0.2286
SH-10-TC CTRP2 8.4791 10.4312 5.4003 0.3702
SNU-601 CTRP2 8.5127 9.9977 5.5672 0.1153
SNU-216 CTRP2 8.5185 10.4234 5.4188 0.3236
SNU-719 CTRP2 8.5453 15.3569 3.2711 7.549
NUGC-3 CTRP2 8.6402 10.1695 5.5537 0.11
MKN74 CTRP2 8.9144 10.6276 5.4942 0.1293
SNU-685 CTRP2 8.211 9.4685 5.6412 0.0856
SNG-M CTRP2 8.323 10.04 5.4819 0.2746
SNU-1077 CTRP2 8.3785 10.1083 5.4787 0.2637
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP CTRP2 7.6205 8.9391 5.6071 0.2792
SW579 CTRP2 7.6638 8.9238 5.6301 0.2203
TT CTRP2 7.6916 9.0059 5.611 0.246
CGTH-W-1 CTRP2 7.8458 9.3709 5.5379 0.3328
8305C CTRP2 7.9241 9.2025 5.6297 0.1502
CAL-62 CTRP2 7.9245 9.4775 5.5302 0.3184
FTC-133 CTRP2 8.0134 9.21 5.6596 0.0963
FTC-238 CTRP2 8.0276 9.5621 5.5402 0.2642
BHT-101 CTRP2 8.0454 9.1568 5.689 0.0639
8505C CTRP2 8.5572 10.163 5.5262 0.1539
ML-1 [Human leukemia] CTRP2 8.6237 10.6429 5.3801 0.3591
TT2609-C02 CTRP2 8.6456 10.2785 5.5181 0.1473
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP2 2.5298 3.0963 2.5298 23.4149
HSC-4 CTRP2 2.5426 3.1681 2.5426 23.3294
FaDu CTRP2 2.6782 4.3068 2.6626 22.4783
HSC-3 CTRP2 5.319 6.7047 2.6074 0.1425
YD-8 CTRP2 7.4832 10.1591 5.0264 2.1712
SCC-4 CTRP2 7.6042 16.6382 1.9846 13.7981
PE/CA-PJ49 CTRP2 7.7077 8.9435 5.6401 0.1899
YD-10B CTRP2 7.8079 8.9627 5.671 0.1201
SNU-1076 CTRP2 7.8533 9.3015 5.5667 0.2736
SCC-25 CTRP2 7.8686 9.5985 5.4608 0.4931
PE/CA-PJ34 (clone C12) CTRP2 7.9366 9.3811 5.5705 0.2396
BICR 22 CTRP2 7.966 9.2003 5.6459 0.1203
BICR 6 CTRP2 7.9831 9.0329 5.7091 0.0546
SCC-9 CTRP2 8.0891 13.8652 3.6787 6.594
PE/CA-PJ41 (clone D2) CTRP2 8.1162 9.5725 5.5706 0.1897
CAL-27 CTRP2 8.1271 9.2657 5.6806 0.0615
BICR 31 CTRP2 8.1284 9.6961 5.5309 0.2495
SNU-1066 CTRP2 8.1345 9.5213 5.5955 0.1506
BICR 56 CTRP2 8.1523 9.6593 5.5533 0.2067
BICR 16 CTRP2 8.2023 9.7014 5.5572 0.1884
SNU-46 CTRP2 8.3372 9.9318 5.5261 0.201
PE/CA-PJ15 CTRP2 8.4247 9.9817 5.541 0.1613
Detroit 562 CTRP2 8.5355 10.1494 5.523 0.162
BHY CTRP2 8.6267 10.0942 5.5745 0.0922
SNU-1214 CTRP2 8.6619 10.4577 5.4614 0.217
SNU-899 CTRP2 8.6706 10.1256 5.5791 0.0828
SNU-1041 CTRP2 8.7086 10.2979 5.534 0.1196
BICR 18 CTRP2 8.715 10.527 5.4568 0.2114
CAL-33 CTRP2 8.8706 10.5329 5.511 0.1189
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BC-3C CTRP2 2.9009 4.1496 2.8965 20.9572
HT-1197 CTRP2 4.4006 5.5607 4.3557 11.1039
RT-112 CTRP2 7.096 9.219 5.2243 1.8683
639V CTRP2 7.2364 8.3687 5.6623 0.3239
KU-19-19 CTRP2 7.5849 8.5684 5.727 0.094
CAL-29 CTRP2 7.8624 9.3739 5.5435 0.315
TCCSUP CTRP2 7.9141 9.3409 5.5763 0.2365
647V CTRP2 7.9579 9.3423 5.5927 0.1967
J82 CTRP2 8.0295 10.0508 5.3551 0.6703
SW1710 CTRP2 8.0384 9.8189 5.4489 0.4422
253J-BV CTRP2 8.0521 9.7143 5.4939 0.3427
UM-UC-3 CTRP2 8.0586 9.6474 5.5212 0.2884
JMSU-1 CTRP2 8.0996 9.2909 5.6625 0.0807
253J CTRP2 8.1103 9.3342 5.6515 0.0898
SCaBER CTRP2 8.1988 10.1694 5.383 0.5178
T24 CTRP2 8.2105 16.6829 2.4045 11.2939
5637 CTRP2 8.3952 10.097 5.4891 0.2423
RT-4 CTRP2 8.4437 15.0212 3.3635 7.3326
HT-1376 CTRP2 8.4456 10.2868 5.44 0.3092
UM-UC-1 CTRP2 8.4942 10.1545 5.506 0.193
VM-CUB-1 CTRP2 8.58 10.14 5.5423 0.1312
KMBC-2 CTRP2 8.6395 10.4021 5.4727 0.2064
U-BLC1 CTRP2 8.7844 10.2349 5.5816 0.0688
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.2174 8.7299 5.5074 0.7665

References

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