Details of the Drug

General Information of Drug (ID: DMC6U93)

Drug Name
Torin2
Synonyms
Torin 2; 1223001-51-1; Torin-2; 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one; 9-(6-AMINO-3-PYRIDINYL)-1-[3-(TRIFLUOROMETHYL)PHENYL]-BENZO[H]-1,6-NAPHTHYRIDIN-2(1H)-ONE; CHEMBL1765602; C24H15F3N4O; CHEBI:90682; 9-(6-Aminopyridin-3-Yl)-1-[3-(Trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1h)-One; 9-(6-AMINOPYRIDIN-3-YL)-1-(3-(TRIFLUOROMETHYL)PHENYL)BENZO[H][1,6]NAPHTHYRIDIN-2(1H)-ONE; 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)-phenyl)benzo[h][1,6]naphthyridin-2(1H)-one; BENZO[H]-1,6-NAPHTHYRIDIN-2(1H)-ONE, 9-(6-AMINO-3-PYRIDINYL)-1-[3-(TRIFLUOROMETHYL)PHENYL]-; 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one; cc-275; MLS006011167; GTPL8839; SCHEMBL6876328; AOB3537; DTXSID00679917; EX-A431; HMS3265O05; HMS3265O06; HMS3265P05; HMS3265P06; HMS3651N13; BCP02612; ABP000908; BDBM50341209; MFCD18782652; NSC775727; s2817; ZINC71318831; AKOS024458055; CCG-265003; CS-0236; NSC-775727; PB34957; NCGC00263216-01; NCGC00263216-02; NCGC00263216-09; NCGC00263216-13; 9-(6-AMINO-PYRIDIN-3-YL)-1-(3-TRIFLUOROMETHYL-PHENYL)-1H-BENZO[H][1,6]NAPHTHYRIDIN-2-ONE; AC-31520; AK171126; AS-74405; HY-13002; SMR004702936; AB0035864; DB-084736; FT-0700124; SW218309-2; Y0293; Q-4148; J-519481; BRD-K68174511-001-01-7; Q27089008; 9-(6-amino-3-pyridyl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one; 17G; 9-(6-Amino-3-pyridinyl)-1-[3-(trifl uoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H) -one; 9-(6-AMINOPYRIDIN-3-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H,2H-BENZO[H]1,6-NAPHTHYRIDIN-2-ONE
Indication
Disease Entry ICD 11 Status REF
T-cell leukaemia 2A90 Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 432.4
Logarithm of the Partition Coefficient (xlogp) 4.4
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C24H15F3N4O
IUPAC Name
9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one
Canonical SMILES
C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F
InChI
InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)
InChIKey
GUXXEUUYCAYESJ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
51358113
ChEBI ID
CHEBI:90682
CAS Number
1223001-51-1
TTD ID
D2B7WM
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serine/threonine-protein kinase mTOR (mTOR) TTCJG29 MTOR_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ALK tyrosine kinase receptor (ALK) OTV3P4V8 ALK_HUMAN Drug Response [2]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Post-Translational Modifications [2]
N-myc proto-oncogene protein (MYCN) OTWD33K1 MYCN_HUMAN Gene/Protein Processing [2]
Tissue factor (F3) OT3MSU3B TF_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease T-cell leukaemia
ICD Disease Classification 2A90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serine/threonine-protein kinase mTOR (mTOR) DTT MTOR 2.16E-05 -0.44 -2.3
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 0.2233 10.5867 -2.6495 50.4934
A-673 GDSC1 -8.3325 2.1874 -8.9695 84.9123
MHH-ES-1 GDSC1 -6.5836 1.243 -6.9999 82.1505
ES8 GDSC1 -5.9979 -1.4817 -6.0416 89.4125
ES4 GDSC1 -5.8687 -0.7171 -5.9287 90.6663
EW-24 GDSC1 -5.7672 3.161 -6.5538 76.2994
ES7 GDSC1 -5.7646 -1.0013 -5.8056 91.4911
ES1 GDSC1 -5.6606 -0.786 -5.7367 86.724
U2OS GDSC1 -5.6151 3.4708 -6.4724 75.332
ES8 GDSC1 -5.5299 0.3248 -5.6588 87.331
EW-3 GDSC1 -5.4829 0.4416 -5.6213 86.9413
ES5 GDSC1 -5.4447 -0.3513 -5.5123 89.3277
ES1 GDSC1 -5.4051 0.6367 -5.5606 86.2872
NOS-1 [Human HNSCC] GDSC1 -5.378 -0.1962 -5.4539 88.7949
U2OS GDSC1 -5.3685 1.6689 -5.6652 83.3337
ES6 GDSC1 -5.2842 8.7718 -7.9666 66.7813
MHH-ES-1 GDSC1 -5.2446 -1.3114 -5.2616 92.3108
EW-16 GDSC1 -5.1799 1.4922 -5.4347 83.553
EW-18 GDSC1 -5.1557 -0.9796 -5.1815 91.1778
SK-ES-1 GDSC1 -5.0286 -0.0992 -5.097 88.1818
H-EMC-SS GDSC1 -5.0105 1.6556 -5.2783 82.8447
EW-7 GDSC1 -4.9183 -2.5673 -4.9187 96.3525
HOS GDSC1 -4.8937 1.1912 -5.0856 83.9961
HuO9 GDSC1 -4.8622 -0.4644 -4.9025 89.2331
EW-1 GDSC1 -4.8053 -1.5918 -4.811 93.0838
EW-22 GDSC1 -4.6724 0.3452 -4.7596 86.3079
CADO-ES1 GDSC1 -4.6677 -0.4717 -4.7019 89.061
EW-13 GDSC1 -4.5973 -1.2071 -4.6068 91.5927
SK-PN-DW GDSC1 -4.5622 -1.3937 -4.5683 92.2354
CAL-72 GDSC1 -4.5602 13.7372 -8.9217 64.0039
SJSA-1 GDSC1 -4.3472 9.0091 -7.0752 64.1825
G-292 clone A141B1 GDSC1 -4.1615 2.7125 -4.5517 78.3133
CHSA8926 GDSC1 -3.7369 9.0708 -6.1077 66.1759
ES6 GDSC1 -3.4802 6.4352 -4.851 68.8658
TC-71 GDSC1 -3.396 1.3973 -3.5193 80.0601
CAL-78 GDSC1 -3.0978 1.4729 -3.2121 78.8218
SaOS-2 GDSC1 -2.4349 2.1583 -2.5938 73.991
HuO-3N1 GDSC1 -2.1954 7.1931 -3.739 63.4255
NY GDSC1 -2.1637 3.4929 -2.5482 69.3494
SJSA-1 GDSC1 -1.2689 8.2657 -3.1747 58.4896
EW-24 GDSC1 0.8597 3.6809 0.6972 43.864
MG-63 GDSC1 1.8991 26.0037 -8.5988 46.4511
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 158 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 -3.0761 1.0435 -3.1472 80.1409
CTB-1 GDSC1 -7.4557 10.9017 -10.7787 71.395
SIG-M5 GDSC1 -7.4496 1.612 -7.8993 85.5149
CA46 GDSC1 -7.0978 7.9748 -9.2997 74.1623
PL-21 GDSC1 -6.8674 6.8678 -8.6685 75.3211
JURL-MK1 GDSC1 -6.6703 3.3629 -7.4265 81.0492
MY-M12 GDSC1 -6.3106 2.7458 -6.8924 81.9219
RS4;11 GDSC1 -6.1956 3.3465 -6.9053 80.4743
KCL-22 GDSC1 -6.0543 0.9314 -6.2886 86.0836
GR-ST GDSC1 -6.0353 7.107 -7.8481 73.651
EoL-1 GDSC1 -5.8124 -1.3332 -5.8581 88.7397
BC-3 GDSC1 -5.7512 5.26 -6.941 76.0824
QIMR-WIL GDSC1 -5.735 2.9495 -6.3115 80.6903
BE-13 GDSC1 -5.7235 -0.9022 -5.7935 87.1919
TUR GDSC1 -5.7099 1.8685 -6.0671 83.2614
L-363 GDSC1 -5.6527 -0.1891 -5.7412 88.9664
HAL-01 GDSC1 -5.5156 -1.2882 -5.5386 92.315
Daudi GDSC1 -5.5034 17.9603 -11.7623 63.1663
SUP-B15 GDSC1 -5.4789 -0.0829 -5.568 88.5206
Reh GDSC1 -5.4427 -0.308 -5.5132 89.1909
SU-DHL-16 GDSC1 -5.4424 -4.0303 -5.4424 99.4998
MN-60 GDSC1 -5.3961 15.8055 -10.688 64.2096
SU-DHL-5 GDSC1 -5.3478 -4.1571 -5.3478 99.6959
Ramos.2G6.4C10 GDSC1 -5.3385 -3.3274 -5.3386 98.2727
DoHH2 GDSC1 -5.3012 -3.7269 -5.3012 99.1156
LAMA-84 GDSC1 -5.2189 0.7632 -5.3779 85.7042
THP-1 GDSC1 -5.1753 -2.2048 -5.1777 95.1907
SU-DHL-10 GDSC1 -5.1737 -4.2342 -5.1737 99.8407
SU-DHL-6 GDSC1 -5.1582 -2.8784 -5.1584 97.2099
OPM-2 GDSC1 -5.1433 -3.5327 -5.1433 98.8359
RPMI-8226 GDSC1 -5.1411 -0.0932 -5.2146 88.27
A4/Fukuda GDSC1 -5.1064 -3.1137 -5.1064 97.8672
WIL2 NS GDSC1 -5.0837 1.1192 -5.3575 79.7369
MOLP-8 GDSC1 -5.0325 -0.511 -5.0757 89.5385
CESS GDSC1 -5.0198 -2.0318 -5.0226 94.6312
Jurkat GDSC1 -4.984 -0.4851 -5.027 89.4118
CCRF-CEM GDSC1 -4.9744 -2.0249 -4.977 94.6032
RCH-ACV GDSC1 -4.9641 -1.5949 -4.9713 93.1588
GDM-1 GDSC1 -4.9382 -0.1061 -5.0025 88.1131
NK-92MI GDSC1 -4.9296 -1.6565 -4.9356 93.3559
MOLM-13 GDSC1 -4.8596 -0.2374 -4.9125 88.4668
697 GDSC1 -4.8244 -2.5297 -4.8247 96.2433
L-428 GDSC1 -4.8058 5.6286 -6.0247 73.5901
OCI-M1 GDSC1 -4.7921 -0.773 -4.817 90.2261
BV-173 GDSC1 -4.7752 -0.8737 -4.7962 90.5614
JSC-1 GDSC1 -4.771 3.5261 -5.396 77.688
HEL GDSC1 -4.7707 -0.3633 -4.8134 88.7986
OCI-AML-2 GDSC1 -4.7469 -0.9138 -4.7661 90.6775
ML-2 GDSC1 -4.7466 0.046 -4.8138 87.393
DEL GDSC1 -4.7435 5.6107 -5.9512 73.484
Karpas-620 GDSC1 -4.7267 -2.6811 -4.7268 96.7327
WIL2 NS GDSC1 -4.7016 1.7656 -4.964 82.018
NALM-6 GDSC1 -4.6953 -1.8483 -4.6978 93.9295
KMOE-2 GDSC1 -4.6586 0.1978 -4.7333 86.7748
OCI-Ly19 GDSC1 -4.6321 -0.9088 -4.6492 90.5594
SK-MM-2 GDSC1 -4.6313 5.1683 -5.9239 69.7261
KE-37 GDSC1 -4.6189 -1.8753 -4.6209 93.991
Karpas-299 GDSC1 -4.583 6.3366 -6.0126 71.9148
BC-1 GDSC1 -4.5818 1.419 -4.7838 82.806
Karpas-231 GDSC1 -4.4833 -1.6759 -4.4859 93.1983
Ku812 GDSC1 -4.4653 -1.9068 -4.4665 94.0225
Loucy GDSC1 -4.458 -0.3268 -4.493 88.3015
MOLT-16 GDSC1 -4.4519 -1.5972 -4.4549 92.8887
PF-382 GDSC1 -4.4487 -0.4209 -4.4791 88.6219
LP-1 GDSC1 -4.4331 0.4269 -4.516 85.6768
H9 GDSC1 -4.4165 -0.7027 -4.4356 89.5903
MC116 GDSC1 -4.3285 -2.4428 -4.3286 95.8774
SR GDSC1 -4.314 -1.776 -4.3153 93.4344
MV4-11 GDSC1 -4.3124 -1.2944 -4.3175 91.6418
A3/Kawakami GDSC1 -4.3065 -1.8028 -4.3077 93.5275
SUP-HD1 GDSC1 -4.2655 3.1761 -4.7636 77.3952
EJM GDSC1 -4.2552 0.8226 -4.3656 84.0567
NU-DUL-1 GDSC1 -4.2463 -1.8738 -4.2471 93.739
VAL GDSC1 -4.2449 5.4169 -5.59 68.174
K-562 GDSC1 -4.2096 2.1975 -4.5066 79.8095
Farage GDSC1 -4.156 2.4363 -4.4921 79.0322
EM-2 GDSC1 -4.1357 3.0319 -4.5905 77.438
SUP-M2 GDSC1 -4.1299 0.4236 -4.199 85.1496
NOMO-1 GDSC1 -4.0713 3.5224 -4.6325 76.0935
RPMI-8402 GDSC1 -4.0421 -1.2757 -4.0453 91.223
HH [Human lymphoma] GDSC1 -3.985 3.8988 -4.6317 75.0129
ST486 GDSC1 -3.9814 -1.2042 -3.9849 90.8532
ALL-SIL GDSC1 -3.9787 0.7314 -4.0661 83.7917
SKM-1 GDSC1 -3.9683 0.9691 -4.0779 82.9793
GA-10 GDSC1 -3.9653 -1.7766 -3.9657 93.0386
OCI-AML-5 GDSC1 -3.962 -0.0036 -3.9979 86.3209
SU-DHL-8 GDSC1 -3.9477 -0.9067 -3.9547 89.6555
RPMI-8866 GDSC1 -3.9409 4.4973 -4.744 73.6216
P30/OHK GDSC1 -3.9318 -0.5337 -3.9466 88.2136
L-540 GDSC1 -3.9089 2.022 -4.1534 79.5868
VAL GDSC1 -3.9067 2.4981 -4.2341 78.2485
KMS-12-BM GDSC1 -3.8794 -0.91 -3.8856 89.5413
JJN-3 GDSC1 -3.8784 -0.9095 -3.8847 89.5373
KOPN-8 GDSC1 -3.7918 0.7137 -3.8688 83.42
Karpas-45 GDSC1 -3.7601 0.437 -3.8149 84.3013
MOLT-4 GDSC1 -3.734 -0.7513 -3.7411 88.629
P32/ISH GDSC1 -3.6408 -0.8965 -3.645 88.9704
MEG-01 GDSC1 -3.6119 0.1761 -3.6461 84.8602
BALL-1 GDSC1 -3.611 7.843 -5.4997 67.2806
U266B1 GDSC1 -3.5406 2.6494 -3.8667 76.8183
P12-Ichikawa GDSC1 -3.3871 0.2413 -3.4178 83.9866
SUP-T1 GDSC1 -3.3617 0.4243 -3.4011 83.2503
ALL-PO GDSC1 -3.3464 1.1075 -3.4366 80.8491
MOLT-13 GDSC1 -3.231 1.383 -3.343 79.5728
KG-1 GDSC1 -3.1908 4.6126 -3.9582 71.1332
KY821 GDSC1 -3.1443 3.3948 -3.5931 73.639
HL-60 GDSC1 -3.1303 -0.0057 -3.1452 84.0213
DND-41 GDSC1 -3.1147 2.2664 -3.3392 76.4929
SU-DHL-4 GDSC1 -3.0466 -0.3384 -3.0529 84.9129
HT GDSC1 -3.0131 1.4399 -3.1189 78.6149
NB4 GDSC1 -2.9984 -1.5095 -2.9984 88.8578
SK-MM-2 GDSC1 -2.9749 5.3964 -3.9588 68.9367
MHH-PREB-1 GDSC1 -2.9506 1.1241 -3.0226 79.397
Granta-519 GDSC1 -2.9306 18.7496 -10.0677 55.6068
EoL-1 GDSC1 -2.9164 0.7228 -2.9577 80.6066
TK [Human B-cell lymphoma] GDSC1 -2.872 3.6548 -3.3574 72.0418
BL-41 GDSC1 -2.8356 -1.7397 -2.8356 88.4124
RPMI-6666 GDSC1 -2.8318 3.5319 -3.2844 72.1712
U-698-M GDSC1 -2.8058 5.2585 -3.7314 68.5735
AMO1 GDSC1 -2.7259 0.3305 -2.7433 81.1067
LC4-1 GDSC1 -2.6955 5.6626 -3.7404 67.4826
DB GDSC1 -2.6232 5.1252 -3.4912 68.1195
Sc-1 GDSC1 -2.595 3.4768 -3.0139 71.3457
Jiyoye GDSC1 -2.5794 1.5282 -2.6704 76.5165
ATN-1 GDSC1 -2.5382 4.4773 -3.2077 68.9825
IM-9 GDSC1 -2.5 -0.0766 -2.5045 81.2301
NKM-1 GDSC1 -2.4634 2.5073 -2.6783 73.1752
Hs 445 GDSC1 -2.4332 2.8387 -2.7046 72.1771
OCI-AML-3 GDSC1 -2.325 2.4553 -2.5209 72.6508
BE-13 GDSC1 -2.3119 7.101 -3.8296 63.9867
Mono-Mac-6 GDSC1 -2.2665 2.6444 -2.4894 71.8701
CTV-1 GDSC1 -2.2194 4.112 -2.7606 68.3158
HC-1 GDSC1 -2.0268 11.3519 -5.2758 59.2086
L-1236 GDSC1 -1.9485 11.156 -5.1095 59.0777
YT GDSC1 -1.8022 5.9292 -2.8605 63.3539
HDLM-2 GDSC1 -1.5834 5.7114 -2.5494 62.5863
DG-75 GDSC1 -1.5248 12.9571 -5.4852 56.7571
EHEB GDSC1 -1.508 3.6023 -1.8593 65.5091
KMS-11 GDSC1 -1.3009 9.0347 -3.5271 58.0732
RC-K8 GDSC1 -1.2164 3.5367 -1.5273 63.7253
VL51 GDSC1 -0.9067 9.2224 -3.1967 56.2435
SU-DHL-1 GDSC1 -0.8086 1.6245 -0.8299 63.2653
EB2 GDSC1 -0.6988 4.9476 -1.3401 58.2527
ME1 GDSC1 -0.5723 40.3893 -17.9369 51.1943
Karpas-422 GDSC1 -0.5556 12.6932 -4.3962 53.5049
Raji GDSC1 -0.449 30.6965 -13.0256 51.3504
SCC-3 GDSC1 -0.3707 3.0907 -0.5233 57.3583
P31/FUJ GDSC1 0.0507 6.6571 -1.1344 51.9714
ROS-50 GDSC1 0.5315 44.124 -18.8199 49.7368
WSU-NHL GDSC1 0.74 5.9921 -0.1431 46.4301
JVM-3 GDSC1 1.6972 5.5302 1.056 36.2047
ARH-77 GDSC1 1.999 8.1019 0.2655 37.3063
WSU-DLCL2 GDSC1 2.1464 6.6683 1.0605 33.3916
MLMA GDSC1 2.5268 13.4986 -1.8366 39.6594
Granta-519 GDSC1 3.5722 21.1927 -4.7461 40.1982
RL GDSC1 5.6001 17.9736 -1.4701 28.8625
KM-H2 GDSC1 6.5317 8.3117 3.7343 0.6412
JVM-2 GDSC1 6.8052 9.3859 3.439 1.6713
⏷ Show the Full List of 158 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1 -4.626 9.3084 -7.4912 64.6398
KYAE-1 GDSC1 -4.4096 3.423 -4.9774 77.1417
ESO-26 GDSC1 -4.1503 3.9838 -4.834 75.252
OACP4 C GDSC1 -4.0876 0.5454 -4.1643 84.6499
OACM5.1 C GDSC1 -3.0817 10.9682 -6.1993 62.6196
KYSE-220 GDSC1 -1.4485 3.3429 -1.7378 65.6221
KYSE-220 GDSC1 -1.3945 2.355 -1.5972 57.353
FLO-1 GDSC1 -1.3675 4.7221 -2.0009 62.8036
TE-12 GDSC1 -1.1883 19.8366 -8.3986 53.8816
HCE-4 GDSC1 -1.1593 4.3395 -1.6647 62.088
KYSE-50 GDSC1 -0.7266 4.6684 -1.2861 58.7358
SK-GT-4 GDSC1 -0.55 8.0775 -2.3419 55.1
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -5.7717 5.9685 -7.1835 74.9214
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-YS GDSC1 -5.9581 -2.5039 -5.9627 95.8887
SK-N-AS GDSC1 -5.506 6.5679 -7.3595 69.9254
NB1 GDSC1 -5.2498 -2.2947 -5.252 95.464
GOTO GDSC1 -5.1756 7.8806 -7.1939 70.9672
GI-ME-N GDSC1 -5.1275 11.3508 -8.4975 67.0522
CHP-212 GDSC1 -5.0706 -0.2911 -5.1605 84.0634
KP-N-YN GDSC1 -5.0404 5.6792 -6.296 74.0021
SiMa GDSC1 -4.9336 0.8595 -5.0866 85.0479
SJNB-14 GDSC1 -4.813 -0.5382 -4.8482 89.4376
Kelly GDSC1 -4.6649 0.4556 -4.7614 85.9373
SK-N-BE(2)-M17 GDSC1 -4.5053 -0.0523 -4.5567 87.4098
CHP-212 GDSC1 -4.4647 -0.6769 -4.4857 89.5553
SK-N-MC-IXC GDSC1 -4.4272 -1.848 -4.4286 93.7852
SJNB-7 GDSC1 -4.4138 0.7429 -4.5247 84.6058
NB69 GDSC1 -4.2918 -1.4132 -4.2955 92.0623
SJNB-14 GDSC1 -4.2374 4.3207 -5.2207 69.9531
SJNB-13 GDSC1 -3.9897 0.9889 -4.1025 82.9624
LA-N-6 GDSC1 -3.9871 2.8442 -4.3894 77.5415
NB(TU)1 GDSC1 -3.9318 2.655 -4.2914 77.8932
SJNB-17 GDSC1 -3.8271 5.8776 -5.0401 70.7552
CHP-134 GDSC1 -3.7561 -0.9249 -3.761 89.3465
SK-N-FI GDSC1 -3.6981 1.0584 -3.8021 82.0264
SJNB-12 GDSC1 -3.6683 1.8415 -3.8674 79.4812
SJNB-5 GDSC1 -3.474 2.2281 -3.7194 77.7843
IMR-5 GDSC1 -3.3318 0.7931 -3.3945 81.865
NH-12 GDSC1 -3.2723 8.9418 -5.5638 65.0412
SK-N-SH GDSC1 -3.1239 1.1275 -3.2046 80.0347
MHH-NB-11 GDSC1 -2.8647 1.5112 -2.9698 77.8107
SK-N-DZ GDSC1 -2.6749 11.5855 -6.0439 61.0138
SJNB-10 GDSC1 -2.2647 1.5903 -2.345 74.7399
SK-N-AS GDSC1 2.1925 11.9936 -1.4066 40.2838
SJNB-6 GDSC1 2.3551 7.8565 0.2059 26.4845
KP-N-YN GDSC1 2.5616 8.0371 0.3042 25.0442
TGW GDSC1 3.9434 4.6536 3.7875 5.8224
SJNB-6 GDSC1 5.5674 24.4662 -4.732 35.4481
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -4.8603 3.0697 -5.3869 78.9269
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFM-223 GDSC1 -6.5966 4.6083 -7.8792 75.2046
UACC-893 GDSC1 -6.1903 3.0706 -6.8345 81.0569
HCC1500 GDSC1 -5.9807 14.3381 -10.6476 66.1838
MDA-MB-468 GDSC1 -5.9221 2.1321 -6.3449 82.8703
Hs 578T GDSC1 -5.6856 1.9973 -6.0641 82.9036
MRK-nu-1 GDSC1 -5.5603 -3.766 -5.5603 99.0294
EFM-19 GDSC1 -5.4976 3.5293 -6.1888 79.0288
OCUB-M GDSC1 -5.4815 -3.2106 -5.4817 97.9212
HCC1599 GDSC1 -5.388 -3.3209 -5.388 98.2306
BT-474 GDSC1 -5.295 0.8926 -5.4743 85.4136
HCC1954 GDSC1 -5.1286 5.4778 -6.3291 74.5312
MDA-MB-453 GDSC1 -5.1271 -0.6088 -5.1682 89.9344
HCC1187 GDSC1 -5.0028 0.8218 -5.1556 85.2564
CAMA-1 GDSC1 -4.965 3.7087 -5.6525 77.6714
DU4475 GDSC1 -4.9636 -2.2657 -4.9649 95.3905
MDA-MB-415 GDSC1 -4.8005 6.5972 -6.6115 68.1178
MDA-MB-361 GDSC1 -4.7028 0.2661 -4.7849 86.609
ZR-75-30 GDSC1 -4.6802 12.0834 -8.3355 65.5092
UACC-893 GDSC1 -4.5226 5.6965 -5.9877 68.5979
AU565 GDSC1 -4.4205 3.2182 -4.9418 77.6513
HCC1569 GDSC1 -4.2846 4.3496 -5.0782 74.8074
MFM-223 GDSC1 -4.1423 2.3665 -4.4643 79.1889
COLO 824 GDSC1 -3.871 0.5194 -3.9362 84.2746
HCC1419 GDSC1 -3.8249 3.3312 -4.3193 75.8959
HCC1806 GDSC1 -3.6344 2.5974 -3.9583 77.2343
BT-483 GDSC1 -3.5576 37.2427 -19.0916 55.1844
HCC38 GDSC1 -3.1945 2.4115 -3.4495 76.362
Evsa-T GDSC1 -3.1927 4.0455 -3.8052 72.3182
HCC202 GDSC1 -3.165 8.4232 -5.2456 65.2972
BT-549 GDSC1 -3.106 4.7879 -3.9163 70.5034
HCC2157 GDSC1 -3.0679 2.109 -3.2642 76.7783
MDA-MB-330 GDSC1 -2.9536 2.4836 -3.2023 75.2948
MDA-MB-175-VII GDSC1 -2.7678 4.6702 -3.5131 69.5135
HCC70 GDSC1 -2.6371 0.5332 -2.6602 79.9881
MCF-7 GDSC1 -2.28 8.4113 -4.3012 62.4126
YMB-1-E GDSC1 -1.7851 12.7417 -5.6495 57.6737
EFM-192A GDSC1 -1.6538 12.0495 -5.2049 57.6018
CAL-120 GDSC1 -1.5946 43.0441 -20.1667 52.3491
HCC1428 GDSC1 -1.3523 17.0924 -7.2435 54.8786
MDA-MB-415 GDSC1 -1.0084 3.8576 -1.3753 61.7639
BT-474 GDSC1 -0.9857 8.5959 -3.413 51.649
CAL-148 GDSC1 -0.9535 17.8805 -7.2345 53.6476
BT-20 GDSC1 -0.9118 4.4811 -1.4341 60.249
HCC2218 GDSC1 -0.8818 8.4497 -2.8442 56.5691
HDQ-P1 GDSC1 -0.5294 6.3663 -1.6437 55.9667
MDA-MB-436 GDSC1 -0.1947 11.2463 -3.37 52.3635
MDA-MB-231 GDSC1 0.1079 8.1659 -1.6926 51.3296
HCC1937 GDSC1 0.5074 7.2134 -0.8753 48.6665
CAL-51 GDSC1 0.7291 64.7614 -28.9416 49.6512
HCC1395 GDSC1 0.7753 9.1307 -1.4324 47.2696
CAL-85-1 GDSC1 1.3239 15.0844 -3.7244 46.1382
MDA-MB-157 GDSC1 1.4676 9.4758 -0.8984 42.8896
ZR-75-30 GDSC1 2.638 5.5812 1.5817 16.3494
T-47D GDSC1 3.9673 4.7599 3.7657 5.8668
UACC-812 GDSC1 7.5742 32.2277 -7.0219 34.5289
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 64 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF126 GDSC1 -7.0561 2.0741 -7.6891 80.8688
DBTRG-05MG GDSC1 -6.8284 8.6903 -9.5745 70.0462
D-423MG GDSC1 -6.0863 3.1652 -6.9032 76.9401
SF295 GDSC1 -6.0426 3.0289 -6.8194 77.1377
YKG-1 GDSC1 -5.9137 7.4136 -7.823 73.007
D-566MG GDSC1 -5.454 0.8337 -5.7088 81.3556
SW1783 GDSC1 -5.0309 19.5357 -12.4834 59.5142
M059J GDSC1 -4.9594 6.5836 -6.7773 68.557
AM-38 GDSC1 -4.8857 3.3847 -5.4871 78.2408
SF268 GDSC1 -4.844 2.8723 -5.4711 74.6913
D283 Med GDSC1 -4.8082 -0.2925 -4.856 88.598
ONS-76 GDSC1 -4.5811 13.5979 -8.8826 64.1444
GI-1 GDSC1 -4.2558 1.8499 -4.4986 80.8972
D-247MG GDSC1 -4.1526 10.0553 -7.31 62.7424
PFSK-1 GDSC1 -4.1186 1.2442 -4.2676 82.4277
D-336MG GDSC1 -4.0131 4.7479 -5.1134 68.473
YH-13 GDSC1 -3.9211 0.9103 -4.0223 83.0649
MOG-G-CCM GDSC1 -2.9087 6.997 -4.4328 66.2523
Daoy GDSC1 -2.8453 4.2834 -3.4894 70.5763
GaMG GDSC1 -2.6783 4.716 -3.4288 69.0826
GB-1 GDSC1 -2.4961 4.6495 -3.2108 68.4796
D-263MG GDSC1 -2.4832 2.6411 -2.7226 72.9135
CAS-1 GDSC1 -2.1903 4.8998 -2.9509 66.7139
D-542MG GDSC1 -2.1044 4.6948 -2.7966 66.6836
LN-229 GDSC1 -2.0905 6.3706 -3.326 64.0363
D-336MG GDSC1 -2.0811 2.5484 -2.2738 71.1478
KS-1 [Human Krukenberg tumour] GDSC1 -2.0271 4.1692 -2.5659 67.2862
KINGS-1 GDSC1 -1.9673 3.8084 -2.4086 67.6961
U-251MG GDSC1 -1.9508 4.6152 -2.606 66.093
8-MG-BA GDSC1 -1.9106 3.3581 -2.2429 68.335
DK-MG GDSC1 -1.8441 5.1631 -2.6544 64.6658
SF539 GDSC1 -1.746 3.2218 -2.0355 67.6973
SNB-75 GDSC1 -1.7009 8.3586 -3.6678 60.2544
Hs 683 GDSC1 -1.4674 4.1797 -1.9579 64.2426
SW1783 GDSC1 -1.15 6.5806 -2.3893 59.3607
LN-18 GDSC1 -1.0576 4.1423 -1.5008 61.6973
D-423MG GDSC1 -1.0166 12.5284 -4.7798 55.2271
KALS-1 GDSC1 -1.0008 10.4736 -3.8382 56.0118
SF126 GDSC1 -0.8945 5.3402 -1.6783 59.1475
D-566MG GDSC1 -0.8442 2.7998 -0.9852 62.026
NMC-G1 GDSC1 -0.8186 11.4557 -4.0925 54.8819
LNZTA3WT4 GDSC1 -0.6791 5.4009 -1.4645 57.6891
D-247MG GDSC1 -0.6379 3.445 -0.8791 59.4213
M059J GDSC1 -0.3311 7.734 -1.9703 54.0459
LN-405 GDSC1 -0.327 7.3648 -1.8157 54.1793
D-502MG GDSC1 -0.3228 5.6561 -1.1652 55.0315
H4 GDSC1 -0.1623 3.4512 -0.3646 55.0648
SW1088 GDSC1 -0.0662 11.3428 -3.2858 51.7806
U-118MG GDSC1 0.0306 14.8595 -4.8436 51.0487
42-MG-BA GDSC1 0.084 6.7489 -1.135 51.7182
MOG-G-UVW GDSC1 0.2355 6.7698 -0.9824 50.6335
SF268 GDSC1 0.3339 7.336 -1.108 49.9165
D-392MG GDSC1 0.4476 13.6036 -3.8422 49.4939
SF295 GDSC1 0.4819 9.5921 -1.9371 49.104
Onda 11 GDSC1 1.1399 15.8536 -4.2712 47.0373
SK-MG-1 GDSC1 1.2069 11.0528 -1.8947 45.379
T98G GDSC1 1.4079 4.8771 0.9745 38.547
U-87MG ATCC GDSC1 1.8843 14.0146 -2.6805 43.2585
KNS-81-FD GDSC1 2.3043 20.8852 -5.6959 44.2713
DBTRG-05MG GDSC1 2.4509 13.1328 -1.7257 39.7689
Becker GDSC1 3.8171 4.2791 3.782 6.5391
A-172 GDSC1 4.2621 13.7737 -0.4539 29.8636
Onda 10 GDSC1 4.7668 12.6621 0.5165 24.3483
KNS-42 GDSC1 5.512 12.5455 1.155 18.7796
⏷ Show the Full List of 64 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 -6.2967 4.3538 -7.4741 75.082
ETK-1 GDSC1 -4.6964 2.8451 -5.1597 79.1489
TGBC24TKB GDSC1 -1.9393 2.0745 -2.0543 71.541
TGBC1TKB GDSC1 0.456 8.0187 -1.2687 49.1231
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 -6.1492 0.6862 -6.4322 82.9727
AN3-CA GDSC1 -5.7145 -2.2695 -5.7197 95.3043
MFE-319 GDSC1 -4.9941 1.4819 -5.2339 83.3073
EN GDSC1 -4.0555 5.7672 -5.2526 71.556
RL95-2 GDSC1 -3.9108 2.9463 -4.3279 77.0817
MFE-280 GDSC1 -3.8012 2.894 -4.198 76.9214
MFE-296 GDSC1 -2.6134 6.4606 -3.9225 65.9641
RL95-2 GDSC1 -2.4514 6.4663 -4.0487 59.9915
KLE GDSC1 1.8187 17.6885 -4.5471 44.9643
ESS-1 GDSC1 3.8274 4.5979 3.6879 7.1394
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCZ GDSC1 -8.667 9.2158 -11.7384 72.3852
KTCTL-140 GDSC1 -6.8575 3.3467 -7.7939 77.9469
769-P GDSC1 -6.6477 4.2337 -7.6256 79.3226
LB1047-RCC GDSC1 -6.2233 -0.3653 -6.3679 86.0937
KTCTL-1M GDSC1 -6.015 1.3012 -6.3957 81.1197
VMRC-RCZ GDSC1 -5.8365 7.1195 -7.6371 73.2829
KTCTL-21 GDSC1 -5.546 9.3725 -8.1506 69.876
KTCTL-26A GDSC1 -5.5059 4.7348 -6.732 72.7278
LB996-RCC GDSC1 -5.3304 4.0812 -6.3384 73.4786
TK-10 GDSC1 -5.1534 1.7289 -5.5463 78.2517
KTCTL-140 GDSC1 -5.1503 4.7349 -6.131 75.9347
KTCTL-13 GDSC1 -5.0852 1.1868 -5.3707 79.5502
LB2241-RCC GDSC1 -3.6932 9.8763 -6.3848 65.2267
KTCTL-195 GDSC1 -3.3734 8.4983 -5.4967 65.8209
HA7-RCC GDSC1 -3.2561 11.2906 -6.5178 62.8301
786-O GDSC1 -3.094 4.5113 -3.8238 71.0069
KTCTL-13 GDSC1 -3.0342 3.4664 -3.4896 73.079
KTCTL-26A GDSC1 -3.0086 3.8901 -3.5644 72.0168
NCC021 GDSC1 -2.8653 5.6566 -3.9229 68.1096
CAL-54 GDSC1 -2.7385 10.9489 -5.8348 61.6654
SW13 GDSC1 -2.5996 8.0599 -4.5021 63.9013
TK-10 GDSC1 -2.2632 3.8238 -2.735 69.1112
LB1047-RCC GDSC1 -1.9985 4.4107 -2.6002 66.6926
KTCTL-1M GDSC1 -1.9551 3.71 -2.3715 67.8333
ACHN GDSC1 -1.4037 15.3813 -6.4866 55.5
SN12C GDSC1 -1.0989 6.234 -2.2078 59.4276
SW156 GDSC1 -0.9527 7.9001 -2.6927 57.2698
UO-31 GDSC1 -0.9016 11.9473 -4.3991 55.0197
BB65-RCC GDSC1 -0.7858 9.1707 -3.0492 55.7196
LB996-RCC GDSC1 -0.7414 3.9399 -1.1044 59.6718
OS-RC-2 GDSC1 -0.6876 8.9054 -2.8339 55.388
VMRC-RCW GDSC1 0.6273 6.5191 -0.4675 47.5867
BFTC-909 GDSC1 0.801 16.0362 -4.6775 48.3196
Caki-1 GDSC1 1.1695 10.9064 -1.862 45.53
A-704 GDSC1 2.0171 7.4827 0.5663 36.1812
KMRC-1 GDSC1 2.6461 13.1204 -1.5416 38.6685
RXF 393L GDSC1 2.8035 10.761 -0.2366 34.8647
KMRC-20 GDSC1 2.9804 11.2307 -0.3056 34.3031
A-498 GDSC1 5.307 8.2056 3.127 6.3786
RCC10RGB GDSC1 6.8756 25.9068 -4.4232 32.2118
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 65 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDST8 GDSC1 -6.922 1.9316 -7.5109 80.9994
HCT 116 GDSC1 -6.0222 1.4176 -6.4259 80.8334
SW626 GDSC1 -4.7483 7.9712 -7.0805 66.3152
RKO GDSC1 -4.5369 1.9584 -4.8184 81.1672
LoVo GDSC1 -4.2014 7.7782 -6.4238 65.0118
CL-11 GDSC1 -4.1905 6.9724 -6.0987 65.9006
SW48 GDSC1 -4.1441 5.4061 -5.4772 67.8692
SNU-81 GDSC1 -3.9503 4.0317 -4.6282 74.6285
HT115 GDSC1 -3.9224 9.1112 -6.6721 62.8911
HCT 15 GDSC1 -3.661 8.3694 -6.091 62.7684
GP5d GDSC1 -3.5238 1.4956 -3.7414 73.483
LoVo GDSC1 -3.2086 2.4816 -3.477 76.2156
CaR-1 GDSC1 -3.1636 4.4482 -4.0927 65.6875
LS513 GDSC1 -2.9736 7.2046 -4.5785 66.1891
LS411N GDSC1 -2.9205 6.5754 -4.2946 66.8808
SNU-C2B GDSC1 -2.881 7.1928 -4.7915 61.1265
C2BBe1 GDSC1 -2.8605 14.7683 -8.1172 56.6246
COLO 320HSR GDSC1 -2.4837 10.8199 -5.5156 61.0043
SW620 GDSC1 -2.4471 5.5473 -3.6964 60.902
SNU-175 GDSC1 -2.2236 3.777 -2.6803 69.0246
CaR-1 GDSC1 -1.9556 6.5949 -3.2608 63.1743
SW837 GDSC1 -1.9451 6.1036 -3.0753 63.7675
CCK-81 GDSC1 -1.8499 2.408 -2.004 70.1655
HCT 116 GDSC1 -1.44 2.4644 -1.5737 67.3262
HCT 15 GDSC1 -1.3723 11.1202 -4.504 57.1105
RCM-1 [Human ESC] GDSC1 -1.3151 2.855 -1.6192 56.2147
SNU-C2B GDSC1 -1.2848 5.0327 -2.0048 61.8842
SNU-407 GDSC1 -1.1576 10.1425 -3.8536 56.8096
LS180 GDSC1 -1.0707 5.5963 -1.9547 59.9417
T84 GDSC1 -1.0281 5.5327 -2.1702 52.5571
GP5d GDSC1 -0.7856 2.8117 -0.9242 61.4999
COLO205 GDSC1 -0.6825 5.2739 -1.4263 57.8281
NCI-H747 GDSC1 -0.6091 13.4872 -4.8185 53.5094
SNU-1040 GDSC1 -0.5927 4.2999 -1.0355 58.1234
CW-2 GDSC1 -0.5757 7.5867 -2.5479 49.3707
RCM-1 [Human ESC] GDSC1 -0.3225 11.4651 -3.5981 52.8681
HT115 GDSC1 -0.2901 4.0652 -0.6435 55.8355
SNU-C1 GDSC1 0.1771 7.472 -1.3287 50.975
SW948 GDSC1 0.2673 3.6565 0.0593 50.5881
C2BBe1 GDSC1 0.4815 15.981 -4.952 49.449
HT-55 GDSC1 0.8284 11.5323 -2.4902 47.5395
HT-55 GDSC1 0.8918 7.3306 -0.9467 38.5384
KM12 GDSC1 0.9083 14.8148 -3.9841 47.7596
KM12 GDSC1 1.1452 6.5113 -0.3176 35.0101
NCI-H716 GDSC1 1.156 4.7705 0.7347 41.3147
SW1417 GDSC1 1.312 7.4122 -0.1223 42.412
HCC2998 GDSC1 1.6395 7.3977 0.2204 39.5402
HT-29 GDSC1 1.7851 4.4492 1.5177 33.307
HT-29 GDSC1 1.9697 5.0725 1.1653 22.4784
SNU-61 GDSC1 2.0756 18.6798 -4.8054 44.3538
SW948 GDSC1 2.6087 4.6702 1.9892 13.4099
SW1463 GDSC1 2.6249 8.6285 0.6307 32.6597
SW48 GDSC1 2.6982 8.2512 0.8816 31.2104
SW626 GDSC1 2.9003 13.9195 -1.7077 38.0134
LS180 GDSC1 2.9862 7.4493 0.9722 19.2073
SNU-C5 GDSC1 3.0443 16.4297 -2.8271 39.3715
SW620 GDSC1 3.1456 13.1937 -1.1287 35.8506
T84 GDSC1 3.1601 10.5957 0.171 31.9368
LS123 GDSC1 3.252 7.7818 1.6357 24.5291
SW1116 GDSC1 3.2565 23.9364 -6.3868 42.3794
CW-2 GDSC1 3.6588 9.7083 1.0579 25.9326
LS1034 GDSC1 5.7927 22.9911 -3.817 33.5221
COLO 678 GDSC1 5.8654 11.4606 1.9427 13.1156
CL-11 GDSC1 7.4137 29.3618 -5.7239 33.1594
MDST8 GDSC1 7.9751 24.8288 -3.0693 27.3424
⏷ Show the Full List of 65 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 0.5803 14.8212 -4.2985 49.034
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-2 GDSC1 -7.2043 2.1433 -7.7361 84.1645
SNU-423 GDSC1 -6.7652 1.4001 -7.1236 85.4931
JHH-4 GDSC1 -6.4662 -0.3559 -6.5788 89.8458
SNU-387 GDSC1 -6.4081 2.592 -6.9652 82.3802
JHH-1 GDSC1 -5.9955 2.5557 -6.5094 81.9566
SNU-387 GDSC1 -5.6002 2.4976 -6.2029 77.3927
SNU-398 GDSC1 -5.3187 1.7669 -5.6279 83.0015
SNU-449 GDSC1 -4.848 4.2092 -5.655 76.3692
Hep 3B2.1-7 GDSC1 -4.796 -1.4919 -4.803 92.732
SNU-475 GDSC1 -4.6483 1.6467 -4.8883 82.2606
Huh-7 GDSC1 -2.5134 5.839 -3.601 66.5109
HLE GDSC1 -0.9198 6.09 -1.9631 58.5542
JHH-7 GDSC1 0.5365 4.996 -0.0112 47.9749
Hep-G2/C3A GDSC1 1.3757 18.8544 -5.5252 46.7609
HuH-1 GDSC1 2.9164 6.2691 2.0228 23.7091
SK-HEP-1 GDSC1 7.686 23.786 -2.7687 27.239
JHH-6 GDSC1 10.7755 34.3697 -5.7227 27.6242
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 192 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-549 GDSC1 -9.2328 2.322 -10.1199 82.7002
NCI-H292 GDSC1 -7.7711 2.1785 -8.4922 81.5446
SW1573 GDSC1 -7.1847 11.0927 -10.9134 68.3119
NCI-H2803 GDSC1 -6.4852 8.3903 -9.0926 69.7398
LXF 289 GDSC1 -6.4654 0.8918 -6.8075 82.878
UMC-11 GDSC1 -6.2654 2.1089 -6.712 83.3284
IST-SL2 GDSC1 -6.1861 4.9041 -7.3099 77.4297
NCI-H2122 GDSC1 -5.7448 -0.9376 -5.8131 87.3363
NCI-H1581 GDSC1 -5.7346 0.5181 -5.8961 86.9471
NCI-H1437 GDSC1 -5.7291 8.1281 -8.1852 68.4882
NCI-H1648 GDSC1 -5.6859 -0.2977 -5.8074 85.1777
HCC15 GDSC1 -5.677 6.4545 -7.5028 70.4733
Calu-3 GDSC1 -5.4348 6.1746 -6.8839 73.9674
NCI-H1648 GDSC1 -5.1175 2.2048 -5.4885 81.541
SBC-1 GDSC1 -5.0193 4.7307 -5.9869 75.681
NCI-H69 GDSC1 -4.9942 2.6613 -5.4446 80.171
NCI-H1048 GDSC1 -4.9846 -0.2996 -5.0382 88.7964
NCI-H1876 GDSC1 -4.8784 0.0634 -4.9524 87.4919
NCI-H1793 GDSC1 -4.6059 45.631 -24.1748 55.354
DMS 114 GDSC1 -4.5517 6.3876 -5.9958 71.7616
HCC78 GDSC1 -4.4775 3.3162 -5.0263 77.5457
NCI-H1304 GDSC1 -4.4221 1.8494 -4.6771 81.247
SBC-3 GDSC1 -4.4171 2.448 -4.7767 79.5874
NCI-H2818 GDSC1 -4.2838 10.1681 -7.126 66.3781
NCI-H2795 GDSC1 -4.2375 2.7362 -4.7756 73.1572
NCI-H1623 GDSC1 -4.2281 -0.051 -4.2699 86.9813
Calu-6 GDSC1 -4.1815 4.7527 -5.0793 73.7388
NCI-H650 GDSC1 -4.1691 11.2212 -7.4396 65.1314
PC-14 GDSC1 -4.0908 3.9116 -4.9362 70.2157
HOP-62 GDSC1 -4.0818 1.9523 -4.3279 80.2091
COR-L303 GDSC1 -3.9815 0.5212 -4.0516 84.5122
COR-L105 GDSC1 -3.9803 12.0018 -7.573 64.0466
NCI-H1341 GDSC1 -3.952 8.5506 -6.1335 67.3231
Lu-139 GDSC1 -3.8469 2.8287 -4.2341 77.2139
LCLC-97TM1 GDSC1 -3.8364 4.8815 -4.7404 72.5733
SBC-5 GDSC1 -3.7961 1.329 -3.9355 81.4028
NCI-H2803 GDSC1 -3.7293 8.273 -5.7892 67.0717
BEN GDSC1 -3.7165 5.1966 -4.7042 71.6405
NCI-H64 GDSC1 -3.6971 -1.1096 -3.6997 89.9315
CAL-12T GDSC1 -3.6524 8.4872 -5.7895 66.61
NCI-H2444 GDSC1 -3.6324 6.3415 -4.9837 69.4556
LB647-SCLC GDSC1 -3.6182 -0.1315 -3.6394 86.006
LB647-SCLC GDSC1 -3.5319 1.0566 -3.6831 74.7339
NCI-H847 GDSC1 -3.4481 0.9089 -3.5254 81.828
NCI-H2347 GDSC1 -3.4314 8.0715 -5.394 66.4897
NCI-H520 GDSC1 -3.3884 10.2431 -6.215 64.0766
Lu-135 GDSC1 -3.3869 -0.3039 -3.3983 86.0006
NCI-H2196 GDSC1 -3.3835 6.8465 -4.8905 67.9672
EPLC-272H GDSC1 -3.3548 1.9091 -3.5418 78.3455
NCI-H2795 GDSC1 -3.3369 0.8371 -3.4032 81.7303
NCI-H2804 GDSC1 -3.2506 7.0658 -5.1332 62.6601
NCI-H524 GDSC1 -3.2098 0.8608 -3.2723 81.231
NCI-H446 GDSC1 -3.2025 -0.6263 -3.2064 86.5935
NCI-H1155 GDSC1 -3.1793 5.8463 -4.3261 68.864
NCI-H322M GDSC1 -3.1786 2.457 -3.4403 76.1807
NCI-H727 GDSC1 -3.0715 4.7864 -3.8782 70.388
NCI-H2810 GDSC1 -3.0145 6.8827 -4.8104 61.9564
NCI-H1944 GDSC1 -2.9301 3.4668 -3.3764 72.6968
NCI-H2171 GDSC1 -2.9287 -0.5945 -2.931 85.317
NCI-H187 GDSC1 -2.8929 3.0602 -3.2467 73.5468
LC-2/ad GDSC1 -2.8897 2.122 -3.0752 76.0693
NCI-H1734 GDSC1 -2.8797 9.882 -5.5321 62.9693
NCI-H596 GDSC1 -2.8371 7.3802 -4.497 65.5115
NCI-H1781 GDSC1 -2.8211 5.0001 -3.6687 69.0931
NCI-H1105 GDSC1 -2.821 2.776 -3.1122 73.9963
NCI-H1792 GDSC1 -2.7908 1.1659 -2.8589 78.6053
Ms-1 GDSC1 -2.784 0.1963 -2.7983 81.8449
NCI-H146 GDSC1 -2.7701 2.4876 -3.0052 74.5627
NCI-H2135 GDSC1 -2.7116 5.6926 -3.7677 67.4934
IST-SL1 GDSC1 -2.6767 2.7029 -2.9426 73.5993
COLO 668 GDSC1 -2.5847 3.0232 -2.9048 72.3895
NCI-H2087 GDSC1 -2.5793 7.5079 -4.6003 59.6299
COR-L311 GDSC1 -2.5722 0.4686 -2.5911 79.8703
CPC-N GDSC1 -2.5557 1.1326 -2.6106 77.6358
NCI-H226 GDSC1 -2.5299 2.9376 -2.8283 72.3643
NCI-H1563 GDSC1 -2.5044 4.6007 -3.4266 62.3289
DMS 273 GDSC1 -2.4298 3.872 -3.1135 62.9396
NCI-H2291 GDSC1 -2.4191 13.2617 -6.5249 59.2532
NCI-H1770 GDSC1 -2.3665 3.2077 -2.7061 70.9675
NCI-H835 GDSC1 -2.3207 3.1086 -2.6358 70.9881
NCI-H1694 GDSC1 -2.2992 3.1832 -2.6279 70.7093
NCI-H2066 GDSC1 -2.2914 4.3435 -2.9012 68.1873
NCI-H211 GDSC1 -2.2812 5.7156 -3.3079 65.7711
DMS 273 GDSC1 -2.2323 8.554 -4.3079 62.101
NCI-H2087 GDSC1 -2.2314 12.9133 -6.1782 58.9159
EMC-BAC-2 GDSC1 -2.1858 3.1571 -2.4994 70.2185
EKVX GDSC1 -2.172 5.7358 -3.1961 65.2806
NCI-H2141 GDSC1 -2.1197 5.0156 -2.9091 66.1984
NCI-H1666 GDSC1 -2.0595 7.7575 -3.8094 62.2622
ABC-1 GDSC1 -2.0442 6.3599 -3.2722 63.8546
NCI-H290 GDSC1 -2.0224 6.5001 -3.2987 63.5793
NCI-H2081 GDSC1 -1.9987 3.2946 -2.3251 68.9463
NCI-H1573 GDSC1 -1.9269 4.3218 -2.4976 66.5013
NCI-H1435 GDSC1 -1.9057 4.4541 -2.5111 66.155
NCI-H1688 GDSC1 -1.8661 5.2344 -2.7008 64.6615
ABC-1 GDSC1 -1.865 5.9875 -3.2382 57.4812
NCI-H661 GDSC1 -1.7731 4.6493 -2.422 65.142
LK-2 GDSC1 -1.7695 3.2411 -2.065 67.7936
NCI-H82 GDSC1 -1.7664 1.5519 -1.8191 71.7464
PC-14 GDSC1 -1.71 2.8036 -1.9172 68.3889
COR-L88 GDSC1 -1.607 3.0496 -1.8508 67.2165
COR-L321 GDSC1 -1.5184 3.8898 -1.9392 65.0475
NCI-H358 GDSC1 -1.5092 5.1324 -2.2803 62.9991
NCI-H647 GDSC1 -1.503 1.9657 -1.5799 68.8613
NCI-H1568 GDSC1 -1.477 4.9354 -2.1842 63.1098
Lu-65 GDSC1 -1.4716 10.0557 -4.1396 58.087
NCI-H292 GDSC1 -1.3097 7.089 -2.7519 59.6807
NCI-H510A GDSC1 -1.2961 3.1087 -1.5257 65.0352
PaCa-3 GDSC1 -1.2523 4.6615 -1.8575 62.207
A-427 GDSC1 -1.2286 2.6398 -1.373 65.4138
NCI-H1869 GDSC1 -1.197 10.2174 -3.9268 56.9262
NCI-H2810 GDSC1 -1.1668 4.1103 -1.6117 62.4757
NCI-H1975 GDSC1 -1.0646 6.2934 -2.1923 59.1804
HCC33 GDSC1 -0.9836 2.3511 -1.073 63.9166
NCI-H2591 GDSC1 -0.7595 13.4588 -4.9537 54.0413
NCI-H23 GDSC1 -0.7588 3.455 -1.0124 60.4145
NCI-H226 GDSC1 -0.6154 35.1048 -15.9592 49.9041
NCI-H1755 GDSC1 -0.4336 2.8465 -0.5522 58.1891
NCI-H1915 GDSC1 -0.4023 3.1226 -0.5628 57.6342
NCI-H2029 GDSC1 -0.3115 7.6297 -1.907 53.9756
HARA [Human squamous cell lung carcinoma] GDSC1 -0.2894 4.9908 -0.9079 55.194
Lu-165 GDSC1 -0.2652 11.7873 -3.6888 52.561
LC-1/sq GDSC1 -0.2328 3.7318 -0.6767 45.5363
NCI-H2731 GDSC1 -0.1991 7.5122 -1.7406 53.3512
NCI-H1355 GDSC1 -0.0167 5.1411 -0.6596 52.9272
NCI-H2804 GDSC1 0.165 7.9481 -1.5407 51.0032
SW1271 GDSC1 0.2418 7.0828 -1.1013 50.5675
NCI-H460 GDSC1 0.2476 3.148 0.1323 50.8433
SHP-77 GDSC1 0.5093 4.6705 0.0609 48.1638
NCI-H3255 GDSC1 0.5541 4.3683 0.1972 47.6263
NCI-H1650 GDSC1 0.8014 3.0057 0.7431 44.2331
Lu-134-A GDSC1 0.8082 27.9647 -10.5418 49.0251
HCC827 GDSC1 0.8339 10.5633 -2.0309 47.2935
IA-LM GDSC1 0.8455 10.8621 -2.1588 47.302
NCI-H2405 GDSC1 0.9015 15.0977 -4.1275 47.8275
HCC44 GDSC1 0.9055 2.4591 0.8944 42.7616
NCI-H841 GDSC1 0.9213 12.1452 -2.69 47.2107
NCI-H2030 GDSC1 0.968 7.8831 -0.6815 45.4736
NCI-H1836 GDSC1 1.0764 9.3066 -1.2094 45.4057
DMS 53 GDSC1 1.1443 11.6963 -2.2607 45.959
NCI-H522 GDSC1 1.2785 8.5722 -0.6719 43.5887
NCI-H1651 GDSC1 1.3076 6.8542 0.1117 41.9301
NCI-H2869 GDSC1 1.5666 38.9712 -15.3493 48.1813
NCI-H2342 GDSC1 1.6372 10.9226 -1.416 42.799
NCI-H2228 GDSC1 1.6976 18.6748 -5.1438 45.6564
NCI-H2595 GDSC1 1.7203 7.0536 0.4542 38.3375
LCLC-103H GDSC1 1.995 8.6261 0.0183 38.0702
NCI-H441 GDSC1 2.195 10.3485 -0.6065 38.6586
EMC-BAC-1 GDSC1 2.2253 22.5486 -6.5926 44.9511
NCI-H2369 GDSC1 2.2972 9.6889 -0.1917 37.1021
A-549 GDSC1 2.4449 4.9106 2.0872 25.8162
NCI-H1436 GDSC1 2.6057 17.5068 -3.7502 41.8872
NCI-H196 GDSC1 2.7736 6.9522 1.567 27.2858
ChaGo-K-1 GDSC1 2.968 8.943 0.8047 30.236
NCI-H2170 GDSC1 2.9805 6.2181 2.1105 22.7965
NCI-H2009 GDSC1 3.0352 15.9834 -2.613 39.0838
NCI-H1838 GDSC1 3.065 16.03 -2.61 38.9806
NCI-H3122 GDSC1 3.1451 18.6727 -3.8563 40.389
NCI-H513 GDSC1 3.1894 15.6728 -2.3229 38.1019
NCI-H2122 GDSC1 3.2832 12.3757 -0.6002 33.9303
NCI-H2461 GDSC1 3.306 14.6569 -1.7148 36.5619
NCI-H345 GDSC1 3.3444 21.2453 -4.9675 41.0041
RERF-LC-KJ GDSC1 3.4811 8.6568 1.4193 24.7544
NCI-H1563 GDSC1 3.747 4.3237 3.694 7.5348
RERF-LC-MS GDSC1 3.748 4.3194 3.6962 7.5141
LXF 289 GDSC1 3.7652 4.3722 3.7 7.3907
NCI-H810 GDSC1 3.792 4.5238 3.6781 7.3964
Lu-99A GDSC1 3.7986 11.1478 0.4636 28.1306
COR-L23 GDSC1 3.8006 20.9787 -4.4448 39.278
NCI-H209 GDSC1 3.8069 12.0531 0.0192 29.8604
NCI-H526 GDSC1 3.8072 4.3532 3.7514 6.8025
NCI-H1993 GDSC1 3.8415 4.5849 3.7081 6.9208
NCI-H720 GDSC1 3.8471 4.2629 3.8186 6.12
HCC15 GDSC1 3.8593 10.8768 0.6514 27.0661
RERF-LC-Sq1 GDSC1 3.9235 8.4374 1.9234 19.7832
NCI-H1092 GDSC1 3.9303 13.2504 -0.4728 31.0976
NCI-H1703 GDSC1 3.9592 4.7168 3.7766 5.8247
COR-L95 GDSC1 3.9928 15.9649 -1.776 34.3904
NCI-H2023 GDSC1 4.0231 4.676 3.8599 4.8933
SK-LU-1 GDSC1 4.4327 18.9178 -2.8839 35.3052
EBC-1 GDSC1 4.4745 20.7872 -3.7839 36.6677
NCI-H2373 GDSC1 4.589 38.48 -12.5351 43.1653
SK-MES-1 GDSC1 4.6055 6.4879 3.4652 5.7961
LOU-NH91 GDSC1 4.7132 15.2979 -0.8435 29.6225
NCI-H1437 GDSC1 4.9272 7.7433 3.0857 7.745
KNS-62 GDSC1 4.9451 18.2986 -2.1541 32.3989
NCI-H2722 GDSC1 5.4872 22.0601 -3.5958 33.8554
SW1573 GDSC1 5.5383 20.377 -2.7158 32.0483
NCI-H1299 GDSC1 5.9782 11.4534 2.0243 12.2882
NCI-H838 GDSC1 6.3492 7.5989 3.9197 0.1985
NCI-H2172 GDSC1 6.3903 9.742 3.0797 4.3464
NCI-H2110 GDSC1 6.4346 9.0592 3.3962 2.3483
⏷ Show the Full List of 192 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -5.9428 5.9249 -7.3558 75.2905
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-5 GDSC1 -6.4248 2.1814 -6.8989 83.3328
KYSE-150 GDSC1 -6.4044 2.4291 -6.9269 82.7426
KYSE-140 GDSC1 -5.8307 4.665 -6.8535 77.297
KYSE-450 GDSC1 -5.7157 0.2797 -5.8501 87.6199
TE-4 GDSC1 -4.9688 0.0095 -5.0826 82.8479
TE-6 GDSC1 -4.2392 4.285 -5.0111 74.8302
TE-8 GDSC1 -3.8397 7.9932 -5.8011 67.711
TE-15 GDSC1 -3.6495 9.1633 -6.0517 65.8452
KYSE-270 GDSC1 -3.6188 0.9181 -3.7052 82.2822
KYSE-520 GDSC1 -2.5918 7.745 -4.3722 64.233
KYSE-70 GDSC1 -2.3417 3.6262 -2.7728 69.8982
TE-4 GDSC1 -2.3279 1.7023 -2.4231 74.7526
OE19 GDSC1 -1.4516 3.8886 -1.866 64.6456
EC-GI-10 GDSC1 -1.408 4.5059 -1.9825 63.3665
COLO 680N GDSC1 -1.3231 7.0834 -2.764 59.7506
OE33 GDSC1 -1.2789 24.5359 -10.7627 53.3688
OE21 GDSC1 -1.2673 3.4386 -1.5612 64.2425
TE-10 GDSC1 -0.9779 4.1371 -1.4125 61.1552
TE-9 GDSC1 -0.7448 4.0803 -1.1434 59.5299
KYSE-410 GDSC1 -0.5156 6.8425 -1.8097 55.5811
KYSE-180 GDSC1 0.0198 6.7306 -1.1961 52.1702
TE-11 GDSC1 0.8175 4.3942 0.4775 44.7943
T.T GDSC1 2.1189 7.426 0.6946 35.1118
TE-1 GDSC1 4.2787 10.2283 1.3326 21.9864
KYSE-510 GDSC1 8.1843 36.5716 -8.708 35.3455
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TYK-nu GDSC1 -8.3633 3.8415 -9.5761 79.1461
TOV-112D GDSC1 -6.7774 2.3403 -7.448 79.8856
DOV13 GDSC1 -6.3147 2.9597 -7.0981 77.7951
OV-90 GDSC1 -6.2254 3.8748 -7.2534 75.8162
JHOS-2 GDSC1 -6.1068 2.5156 -6.7595 78.3691
TOV-112D GDSC1 -5.3394 3.2074 -5.9397 79.4767
Kuramochi GDSC1 -4.8952 6.0146 -6.5024 69.1756
TYK-nu GDSC1 -4.6145 7.3172 -6.3863 70.5228
A2780 GDSC1 -4.6077 4.1572 -5.3787 75.9611
JHOS-4 GDSC1 -4.2984 3.8363 -4.9576 75.9406
ES-2 GDSC1 -4.2395 6.5668 -5.7183 70.7306
Caov-3 GDSC1 -3.1776 2.7561 -3.4944 75.3668
OV-90 GDSC1 -2.9786 6.3952 -4.2944 67.3409
IGROV-1 GDSC1 -2.7689 20.4987 -10.2343 57.1622
OAW42 GDSC1 -2.5387 6.5213 -3.8633 65.6028
DOV13 GDSC1 -2.2968 6.8071 -3.7052 64.2982
OVK18 GDSC1 -2.1857 9.5173 -4.6536 61.0685
SK-OV-3 GDSC1 -2.0006 7.4176 -3.6156 62.3962
RMG-I GDSC1 -1.9642 9.4023 -4.374 60.3829
OVCAR-4 GDSC1 -1.0851 11.8258 -4.5288 55.741
OVISE GDSC1 -1.0756 6.5879 -2.3122 58.959
OAW28 GDSC1 -0.8359 4.9094 -1.4777 59.2314
JHOS-2 GDSC1 -0.8251 5.7503 -1.7413 58.3047
Kuramochi GDSC1 -0.7488 7.9027 -2.4789 56.2385
EFO-27 GDSC1 -0.5838 11.8812 -4.0502 53.8265
OVCAR-8 GDSC1 -0.315 6.0738 -1.3056 54.7378
Caov-4 GDSC1 -0.1833 6.0511 -1.1557 53.8299
FU-OV-1 GDSC1 0.1737 7.0673 -1.1669 51.0432
OVCAR-3 GDSC1 0.2435 10.5622 -2.6181 50.394
OVKATE GDSC1 0.5567 14.3494 -4.6373 45.2562
OC 314 GDSC1 0.5803 11.8059 -2.8618 48.7967
OVTOKO GDSC1 0.6889 6.108 -0.2418 46.9289
EFO-21 GDSC1 1.1889 29.224 -10.8277 48.3158
OVCAR-5 GDSC1 1.489 27.4607 -9.6856 47.5569
OV56 GDSC1 2.7135 8.4412 0.8055 31.4729
TOV-21G GDSC1 3.8338 4.3422 3.7835 6.433
OVKATE GDSC1 6.6516 8.463 3.7264 0.5932
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PL4 GDSC1 -6.0378 2.4464 -6.6676 78.3944
KP-4 GDSC1 -4.2224 18.4546 -10.7044 60.7059
MZ-PC-1 GDSC1 -3.5677 4.0888 -4.2257 73.4193
Panc 03.27 GDSC1 -3.3906 3.6275 -3.916 73.9071
Panc 04.03 GDSC1 -2.7379 6.9433 -4.2294 65.7424
PaTu 8902 GDSC1 -2.2581 12.1543 -5.8664 59.4288
HuP-T3 GDSC1 -2.0766 11.6912 -5.9144 55.3775
SUIT-2 GDSC1 -1.505 2.5076 -1.6494 67.6936
HuP-T4 GDSC1 -1.1732 2.1204 -1.248 65.9338
HPAF-II GDSC1 -1.0405 7.7593 -2.7286 57.8023
QGP-1 GDSC1 -0.1715 17.843 -6.4708 51.475
Panc 08.13 GDSC1 -0.0924 17.4095 -6.1863 51.2734
BxPC-3 GDSC1 -0.0442 5.4321 -0.7865 53.042
MIA PaCa-2 GDSC1 0.1357 6.7441 -1.0782 51.3539
SU.86.86 GDSC1 0.325 12.6723 -3.5195 49.987
Capan-1 GDSC1 0.3456 6.5784 -0.79 49.8201
CFPAC-1 GDSC1 0.4883 10.7375 -2.4545 49.1596
Panc 02.03 GDSC1 0.7069 11.8764 -2.7711 48.1994
PL4 GDSC1 0.8765 8.4332 -1.0174 46.375
PSN1 GDSC1 2.2639 7.7857 0.6751 34.3771
HPAC GDSC1 2.4359 11.0779 -0.7328 37.8406
Hs 766T GDSC1 2.9677 13.2495 -1.3152 36.9573
PaTu 8988t GDSC1 3.2588 29.3916 -9.1095 43.9143
AsPC-1 GDSC1 3.8464 16.018 -1.9269 35.1889
KP-1N GDSC1 3.87 5.2003 3.4662 8.586
KP-3 GDSC1 3.9091 14.8516 -1.2907 33.5089
DAN-G GDSC1 4.1279 11.4408 0.5995 26.2611
SW1990 GDSC1 4.7664 14.6066 -0.4549 28.1852
HuP-T3 GDSC1 4.9869 16.6262 -1.2852 30.0861
Panc 10.05 GDSC1 5.3479 10.973 1.8079 15.4788
Capan-2 GDSC1 7.0307 29.6115 -6.1424 34.4128
YAPC GDSC1 7.461 19.666 -0.9176 22.4757
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1 -4.4315 6.0076 -5.9998 67.8812
MSTO-211H GDSC1 -2.6105 3.7268 -3.0898 70.8438
MPP 89 GDSC1 -1.1519 5.8934 -2.1444 60.0783
NCI-H2452 GDSC1 -1.037 10.0321 -3.6815 56.3774
NCI-H2052 GDSC1 -0.4352 28.5895 -11.9733 51.4216
IST-Mes1 GDSC1 0.0858 17.2847 -6.5109 47.6138
NCI-H28 GDSC1 0.3951 7.7217 -1.2053 49.5088
IST-Mes1 GDSC1 1.375 16.2458 -4.2444 46.2264
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC1 -5.6231 6.1986 -7.0963 74.283
LNCaP clone FGC GDSC1 -4.6993 6.355 -6.4139 68.1669
PC-3 GDSC1 -3.9106 11.2747 -7.1921 64.4819
VCaP GDSC1 -2.4924 4.5512 -3.1786 68.651
LNCaP clone FGC GDSC1 -2.1983 3.5403 -2.5966 69.4138
DU145 GDSC1 0.9737 10.0388 -1.6489 46.3392
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 -0.4137 10.9143 -3.439 53.3934
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-30 GDSC1 -7.9167 5.2194 -9.2899 79.1659
WM793 GDSC1 -7.7814 6.6623 -9.5927 76.8493
CHL-1 GDSC1 -7.7198 2.9592 -8.4741 82.9403
IPC-298 GDSC1 -7.6327 3.9371 -8.6214 81.0268
WM115 GDSC1 -6.9541 7.2316 -8.8857 74.9384
SK-MEL-5 GDSC1 -6.8712 0.0473 -7.0463 88.9279
SK-MEL-28 GDSC1 -6.5467 9.8843 -9.4152 71.0646
MZ-MEL-2 GDSC1 -6.54 1.2489 -6.9538 82.0741
CP50-MEL-B GDSC1 -6.5176 0.6783 -6.7485 87.1079
G-361 GDSC1 -6.506 -0.1063 -6.6442 89.1809
Mel Ho GDSC1 -6.4972 -1.0658 -6.5586 91.8149
LOX-IMVI GDSC1 -6.4886 -0.1757 -6.6717 85.8303
A101D GDSC1 -6.4621 2.4516 -7.1312 79.1388
WM35 GDSC1 -6.3811 1.9136 -6.8002 83.9158
COLO 679 GDSC1 -6.1705 1.806 -6.553 83.9548
SK-MEL-28 GDSC1 -6.1264 11.9864 -10.1828 65.6713
SK-MEL-2 GDSC1 -6.0944 0.8619 -6.3219 86.3044
HT-144 GDSC1 -6.0272 1.2761 -6.3103 85.1476
A-375 GDSC1 -5.915 0.7324 -6.188 82.4779
VMRC-MELG GDSC1 -5.8796 6.765 -7.5628 73.8763
SK-MEL-3 GDSC1 -5.7457 3.1446 -6.3675 80.2677
MZ-MEL-2 GDSC1 -5.7365 3.2684 -6.3864 79.9802
COLO 800 GDSC1 -5.6881 -3.3195 -5.6883 98.06
CP50-MEL-B GDSC1 -5.6328 4.3494 -6.7494 73.6978
LOX-IMVI GDSC1 -5.4292 1.6927 -5.7344 83.3525
IGR-37 GDSC1 -5.3237 -0.6914 -5.3667 90.3306
451Lu GDSC1 -5.2598 7.1125 -7.0109 72.1979
RPMI-7951 GDSC1 -5.2192 6.5236 -6.7654 72.9947
A-431 GDSC1 -5.0983 -1.5607 -5.1075 93.0871
A-375 GDSC1 -5.0062 13.5967 -9.3205 64.9813
MZ-MEL-7 GDSC1 -5.0031 0.5021 -5.1215 86.239
IGR-1 GDSC1 -4.9341 -2.1094 -4.936 94.8778
Mel JuSo GDSC1 -4.8945 -0.6957 -4.925 90.0468
SH-4 GDSC1 -4.8024 2.2204 -5.1507 80.9555
A-388 GDSC1 -4.8004 2.4133 -5.3117 75.6311
DJM-1 GDSC1 -4.6264 9.5309 -7.2336 67.8146
G-mel GDSC1 -4.5891 -1.6997 -4.5921 93.3519
IST-MEL1 GDSC1 -4.3413 10.9569 -7.5098 65.7579
Hs 938.T GDSC1 -4.2614 15.7529 -9.5109 62.1376
SK-MEL-2 GDSC1 -4.1959 1.6308 -4.4903 75.7644
WM1552C GDSC1 -4.0658 6.3825 -5.4672 70.5751
COLO 792 GDSC1 -3.9565 -0.2426 -3.9816 87.1808
LB2518-MEL GDSC1 -3.5045 2.81 -3.859 76.283
SK-MEL-24 GDSC1 -2.841 5.7142 -3.9153 67.9282
A-388 GDSC1 -2.703 2.8914 -3.0068 73.2204
MMAc-SF GDSC1 -2.5034 18.4579 -9.0102 57.2468
M14 GDSC1 -2.3035 15.2026 -7.2937 58.0014
UACC-62 GDSC1 -2.0498 4.1199 -2.5776 67.4927
RVH-421 GDSC1 -2.0182 50.0352 -24.0118 52.4616
Hs 940.T GDSC1 -1.7951 36.586 -17.154 53.0131
CP66-MEL GDSC1 -1.5241 4.7694 -2.1856 63.6197
COLO 783 GDSC1 -1.4604 13.9493 -5.8762 56.1561
LB373-MEL-D GDSC1 -1.379 17.8975 -7.6522 54.7506
COLO 829 GDSC1 -1.3258 9.0623 -3.5646 58.1584
HMV-II GDSC1 -1.2326 5.5305 -2.1082 60.9485
MeWo GDSC1 -1.0921 5.5754 -1.9708 60.0899
GAK GDSC1 -0.9863 7.8828 -2.7211 57.4471
COLO 829 GDSC1 -0.8698 11.0987 -4.4413 50.8422
A2058 GDSC1 -0.5772 7.6316 -2.1877 55.4807
WM278 GDSC1 -0.4272 8.3672 -2.3347 54.3149
WT2-iPS GDSC1 -0.17 14.5448 -5.4117 48.1585
VMRC-MELG GDSC1 -0.0434 10.6465 -3.4192 46.9144
A101D GDSC1 0.737 30.2499 -11.7387 49.2332
SK-MEL-1 GDSC1 1.2507 23.3243 -7.8461 47.7203
UACC-257 GDSC1 3.2102 15.3561 -2.147 37.7243
WT2-iPS GDSC1 3.992 11.801 0.304 28.0456
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -1.0526 4.6579 -1.6385 60.9615
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GCT GDSC1 -6.6576 7.1361 -8.5319 74.6255
SK-UT-1 GDSC1 -6.5251 8.124 -8.7352 73.0955
Rh41 GDSC1 -5.6544 -4.0739 -5.6544 99.4415
SW872 GDSC1 -5.6352 7.4468 -7.5338 72.4534
G-402 GDSC1 -5.4833 3.4626 -6.157 79.1501
SK-LMS-1 GDSC1 -5.3836 4.9751 -6.4554 75.9315
Hs 633.T GDSC1 -5.3484 -2.4341 -5.3502 95.8688
EW-8 GDSC1 -5.3397 -3.5921 -5.3397 98.8397
SW982 GDSC1 -4.6943 9.4196 -7.2619 68.0856
Rh30 GDSC1 -4.4708 -0.2108 -4.5119 87.9116
RD GDSC1 -4.3404 8.1554 -6.3985 68.7649
G-401 GDSC1 -3.9865 5.9765 -5.2456 71.022
KYM-1 GDSC1 -3.5086 6.2976 -4.8347 69.1629
A-204 GDSC1 -2.8024 12.8581 -6.7341 60.5244
Rh18 GDSC1 -2.6613 2.5174 -2.8931 74.0281
VA-ES-BJ GDSC1 -1.507 34.1303 -15.6808 52.8019
HT-1080 GDSC1 -0.4607 4.2828 -0.8869 57.0944
SW684 GDSC1 0.0986 17.031 -5.8224 50.7087
MES-SA GDSC1 1.9414 10.3623 -0.8555 40.4106
RKN GDSC1 3.2798 21.6752 -5.2378 41.4161
MFH-ino GDSC1 4.8698 20.6198 -3.3751 35.0016
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RERF-GC-1B GDSC1 -6.3878 5.7944 -7.7988 76.2272
AGS GDSC1 -6.1272 -0.4833 -6.2136 90.0779
MKN1 GDSC1 -5.4968 3.6058 -6.2068 78.8625
HSC-39 GDSC1 -5.3456 -3.2458 -5.3457 98.0775
23132/87 GDSC1 -5.2784 6.4893 -6.8181 73.1662
TMK-1 GDSC1 -5.242 0.4988 -5.432 81.9061
GCIY GDSC1 -5.098 -1.9946 -5.1016 94.5168
SNU-1 GDSC1 -4.9631 -0.3941 -5.0104 89.0902
SCH GDSC1 -4.6596 10.4164 -7.6231 66.972
IM95 GDSC1 -4.565 4.4611 -5.415 75.2389
HGC-27 GDSC1 -3.5377 -0.5857 -3.5454 87.5072
TGBC11TKB GDSC1 -3.4115 6.3245 -4.7386 68.83
NCI-N87 GDSC1 -3.4108 12.5917 -7.6654 59.0531
Fu97 GDSC1 -3.3498 15.8096 -8.6181 60.2035
KATO III GDSC1 -3.2063 5.1667 -4.1391 70.1291
ECC10 GDSC1 -2.9667 6.2114 -4.2182 67.5784
OCUM-1 GDSC1 -2.4458 14.5109 -7.1183 58.6834
MKN7 GDSC1 -2.331 6.9109 -3.7799 64.2975
KATO III GDSC1 -1.9273 4.2935 -2.6987 59.4047
NUGC-3 GDSC1 -0.0802 18.1378 -6.5271 51.1893
RF-48 GDSC1 0.1938 9.8049 -2.3244 50.6854
Hs 746.T GDSC1 0.633 17.5615 -5.5772 49.0129
MKN28 GDSC1 2.2497 10.448 -0.6025 38.3896
NUGC-4 GDSC1 2.9332 19.2804 -4.344 41.512
MKN45 GDSC1 3.3284 17.8575 -3.2907 39.1385
SNU-5 GDSC1 3.949 5.7307 3.2869 9.6215
SNU-16 GDSC1 5.7324 11.2367 1.9579 13.3911
NCI-N87 GDSC1 6.3928 20.6529 -2.1885 28.7271
SNG-M GDSC1 -6.6304 1.2587 -6.9552 85.728
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT2609-C02 GDSC1 -8.4293 5.4182 -9.908 79.404
8505C GDSC1 -8.065 1.1906 -8.4882 86.7941
CAL-62 GDSC1 -6.8027 7.0729 -8.6676 74.9346
CGTH-W-1 GDSC1 -6.3266 0.1797 -6.546 84.6275
K5 GDSC1 -6.246 18.1338 -12.5915 64.2396
K5 GDSC1 -5.7717 -1.6892 -5.7993 89.9183
CAL-62 GDSC1 -5.7009 0.5582 -5.9313 82.6091
KMH-2 GDSC1 -5.1554 -1.1066 -5.1768 91.5985
HTC-C3 GDSC1 -5.0796 7.8001 -7.0613 70.8759
IHH-4 GDSC1 -4.9754 -1.6357 -4.9821 93.3006
8505C GDSC1 -4.9595 4.8148 -6.1635 71.2208
B-CPAP GDSC1 -4.9297 0.2517 -5.0212 86.942
8305C GDSC1 -3.854 6.1248 -5.1509 70.4218
BHT-101 GDSC1 -2.3184 5.469 -3.2677 66.313
CGTH-W-1 GDSC1 -1.8514 5.0121 -2.6156 64.9401
ASH-3 GDSC1 -1.4802 3.527 -1.8121 65.4767
ML-1 [Human leukemia] GDSC1 -0.7186 7.5586 -2.3076 56.2915
FTC-133 GDSC1 3.0543 6.176 2.2039 21.789
WRO GDSC1 3.9257 11.9322 0.1818 28.7874
TT GDSC1 3.9823 4.7691 3.7769 5.7108
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-15 GDSC1 -7.0064 3.6479 -7.8636 80.8816
HSC-4 GDSC1 -6.8468 2.28 -7.5093 80.1209
DOK GDSC1 -5.8099 2.6617 -6.4716 77.4638
BB30-HNC GDSC1 -5.7122 1.1146 -5.9489 85.2558
CAL-33 GDSC1 -5.5796 0.2284 -5.7558 83.3735
CAL-27 GDSC1 -5.0204 1.6349 -5.3834 78.172
SCC-9 GDSC1 -4.9856 1.0779 -5.1687 84.4659
LB771-HNC GDSC1 -4.9703 6.2262 -6.6591 69.0742
Ca9-22 GDSC1 -4.6389 1.5782 -4.8679 82.4418
NCI-H3118 GDSC1 -4.5875 1.9932 -4.8787 81.1688
PCI-06A GDSC1 -4.5496 0.7358 -4.6671 84.8576
BHY GDSC1 -4.5412 3.9148 -5.2426 76.3314
PE/CA-PJ15 GDSC1 -4.4495 2.4324 -4.8088 79.698
PCI-15A GDSC1 -4.3416 0.5055 -4.4268 85.2606
SCC-25 GDSC1 -4.2166 8.5797 -6.427 67.9467
PCI-04B GDSC1 -4.0685 2.5417 -4.4174 78.5389
CAL-33 GDSC1 -3.7204 -0.148 -3.7433 86.3195
OSC-20 GDSC1 -3.6238 10.1077 -6.4063 64.8231
BICR 10 GDSC1 -3.2384 6.8055 -4.7193 67.5819
JHU-011 GDSC1 -3.1791 2.3467 -3.4218 76.4903
DOK GDSC1 -2.8431 2.4488 -3.0772 74.9628
HO-1-N-1 GDSC1 -2.4634 4.9312 -3.2581 67.8268
CAL-27 GDSC1 -2.1671 1.1983 -2.2107 75.3198
LB771-HNC GDSC1 -1.6961 5.5427 -2.6155 63.378
OSC-19 GDSC1 -1.2817 4.6022 -1.8723 62.47
BICR 31 GDSC1 -1.2732 21.2366 -9.1549 53.8365
BICR 78 GDSC1 -0.9934 1.4082 -1.0102 65.423
SCC-4 GDSC1 -0.9683 9.3598 -3.3194 56.442
SAT [Human HNSCC] GDSC1 -0.5929 8.194 -2.4353 55.2673
KOSC-2 GDSC1 -0.4241 6.8504 -1.7152 55.02
HSC-2 GDSC1 -0.0035 4.6434 -0.4901 52.9987
SKN-3 GDSC1 0.1066 4.3516 -0.2866 52.0882
Detroit 562 GDSC1 0.361 5.544 -0.3869 49.6631
JHU-022 GDSC1 1.1841 15.4115 -4.0145 46.7775
HO-1-u-1 GDSC1 1.324 5.8868 0.521 40.7396
HSC-3 GDSC1 1.9128 8.6232 -0.0614 38.7372
KON GDSC1 4.6789 6.227 3.648 4.1535
FaDu GDSC1 5.2522 7.0871 3.6162 2.9629
PCI-30 GDSC1 5.587 15.8981 -0.4486 25.6574
HSC-4 GDSC1 6.3467 7.6023 3.9176 0.2037
BICR 22 GDSC1 6.3747 7.8782 3.8308 0.4156
SAS GDSC1 6.7616 8.7887 3.6503 0.7914
PCI-38 GDSC1 6.9863 8.6821 3.7748 0.3009
BB49-HNC GDSC1 7.4036 9.3111 3.7078 0.3074
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1 -7.0028 5.5066 -8.3798 77.585
KU-19-19 GDSC1 -5.1651 0.9339 -5.4144 80.4539
RT-112 GDSC1 -4.6766 0.652 -4.7924 85.3234
SW1710 GDSC1 -3.0854 1.8542 -3.2462 77.5971
5637 GDSC1 -3.0087 1.0284 -3.0755 79.9391
639V GDSC1 -1.7132 8.0554 -3.559 60.578
CAL-29 GDSC1 -1.5684 3.6766 -1.9423 65.7372
T24 GDSC1 -1.5399 11.7962 -4.9758 57.3511
HT-1376 GDSC1 -1.4881 3.8683 -1.9008 64.9036
BFTC-905 GDSC1 -1.4381 4.0982 -1.9045 64.2046
SW780 GDSC1 -0.6522 7.637 -2.269 55.8866
647V GDSC1 -0.3977 4.2141 -0.7997 56.6369
TCCSUP GDSC1 -0.0769 11.2308 -3.245 51.8444
HT-1197 GDSC1 0.8536 159.232 -76.042 49.8157
KU-19-19 GDSC1 1.5296 11.5716 -1.83 43.8156
J82 GDSC1 1.9272 13.3404 -2.3111 42.6849
RT-4 GDSC1 2.1279 5.6236 1.479 31.3808
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 -6.9676 4.6689 -8.0951 78.9522
ME-180 GDSC1 -6.802 3.9869 -7.7281 79.9868
UWB1.289 GDSC1 -6.7442 5.1724 -7.9974 77.7834
SKN GDSC1 -6.4418 2.581 -7.1407 78.8227
SKN GDSC1 -6.1598 7.6639 -8.177 73.0937
Ca Ski GDSC1 -5.9952 0.4113 -6.1599 87.4587
HEY GDSC1 -5.9824 -1.6718 -6.0163 90.0362
C-4-I GDSC1 -5.7061 0.7478 -5.8933 86.2686
C-33 A GDSC1 -5.5624 1.0045 -5.7737 85.3991
ACC-OV7 GDSC1 -5.3341 3.9573 -6.3055 73.7218
BPH-1 GDSC1 -4.3195 -0.0967 -4.3619 87.2904
TC-YIK GDSC1 -4.3135 -0.2066 -4.35 87.6699
SW962 GDSC1 -4.0602 17.2371 -9.9826 60.9663
NEC8 GDSC1 -4.0063 -0.5361 -4.0224 88.3619
LB831-BLC GDSC1 -3.9066 8.5144 -6.4088 63.3894
HEY GDSC1 -3.8642 0.4909 -3.927 84.358
MS751 GDSC1 -3.8609 7.4378 -5.6179 68.4934
HEC-1 GDSC1 -3.8444 7.563 -5.6462 68.2812
NCC-IT GDSC1 -3.84 2.4415 -4.1515 78.2277
DSH1 GDSC1 -3.7089 3.4809 -4.2279 75.2124
PA-1 GDSC1 -3.6033 0.0604 -3.6318 85.2593
OVCA433 GDSC1 -3.4197 7.8726 -5.306 66.7009
SiSo GDSC1 -3.1638 11.1288 -6.353 62.7137
HT-3 GDSC1 -3.1348 8.7925 -5.3587 64.8
NT2-D1 GDSC1 -3.0387 1.3467 -3.1362 79.0091
C-4-I GDSC1 -2.992 1.4853 -3.168 70.8101
DoTc2 4510 GDSC1 -2.3114 2.5781 -2.6399 64.2958
SW954 GDSC1 -2.102 2.5015 -2.2887 71.379
PEO1 GDSC1 -1.9476 4.9358 -2.6972 65.5308
HeLa GDSC1 -1.8613 6.1636 -3.0056 63.3125
JAR GDSC1 -1.3112 1.1633 -1.3263 68.8853
OVMIU GDSC1 -1.0577 8.1582 -2.9084 57.5968
OV17R GDSC1 -0.9805 6.1336 -2.044 58.8629
DoTc2 4510 GDSC1 -0.6339 29.2311 -12.4706 51.7447
ACC-OV7 GDSC1 -0.5879 5.6068 -1.435 56.9029
OMC-1 [Human cervical carcinoma] GDSC1 -0.0656 1.6531 -0.0713 54.7836
LB831-BLC GDSC1 -0.0103 7.2037 -1.4163 52.2561
JEG-3 GDSC1 0.0528 3.4248 -0.1264 52.8997
CAL-39 GDSC1 0.0779 4.3711 -0.3232 52.3513
SiHa GDSC1 0.1641 52.3861 -23.2574 50.1656
JHOS-3 GDSC1 0.2353 8.336 -1.6335 50.5355
OVCA420 GDSC1 1.1762 4.7241 0.7712 41.0362
SW756 GDSC1 1.6475 22.147 -6.907 46.507
PWR-1E GDSC1 3.8537 4.4901 3.7568 6.5086
SKG-IIIa GDSC1 5.1737 9.7892 2.2616 13.0272
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug

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