Details of the Drug

General Information of Drug (ID: DMDZBIQ)

Drug Name
PMI-001
Indication
Disease Entry ICD 11 Status REF
Lupus 4A40 Discontinued in Phase 3 [1]
Affected Organisms
Humans and other mammals
Cross-matching ID
PubChem CID
135497218
UNII
DNY3HZ943X
DrugBank ID
DB05730
TTD ID
D0I9LH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-2 (IL2) TTF89GD IL2_HUMAN Inhibitor [2]
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Lupus
ICD Disease Classification 4A40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostaglandin G/H synthase 2 (COX-2) DTT PTGS2 7.93E-04 -0.29 -0.34
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019789)
2 Development of a botanical anti-arthritis drug, PMI-001. SBIR.STTR America's Seed Fund.