Details of the Drug

General Information of Drug (ID: DMN5T2A)

Drug Name
Ciclopirox
Synonyms
Ciclopiroxum; Cyclopirox; Cyclopyroxolamine; Loprox; Penlac; Stieprox; Terit; Ciclopirox Olamin; Ciclopirox gel; Loprox Gel; Loprox Shampoo; Loprox cream; Penlac nail lacquer; HOE 296b; Batrafen (TN); Ciclopirox-Olamin; Ciclopiroxum [INN-Latin]; Dafnegin-CSC; HOE-296; HOE-296b; Loprox (TN); Penlac (TN); Stieprox (TN); Ciclopirox (USP/INN); Ciclopirox [USAN:BAN:INN]; (6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone); 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone; 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone; 6-Cyclohexyl-1-hydroxy-4-methyl-2-(1H)-pyridone; 6-cyclohexyl-1-hydroxy-4-methyl-2(1 H)-pyridinone; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one; 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
Indication
Disease Entry ICD 11 Status REF
Cutaneous candidiasis 1F23.14 Approved [1]
Fungal infection 1F29-1F2F Approved [2]
Mycoses 1F2Z Approved [1]
Onychomycosis EE12.1 Approved [1]
Pityriasis simplex N.A. Approved [1]
Tinea corporis 1F28.Y Approved [1]
Tinea cruris 1F28.3 Approved [1]
Tinea versicolor 1F2D.0 Approved [1]
Tinea pedis 1F28.2 Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antifungal Agents
Affected Organisms
Humans and other mammalsYeast and other fungi
ATC Code
D01AE14: Ciclopirox
D01AE: Other antifungals for topical use
D01A: ANTIFUNGALS FOR TOPICAL USE
D01: ANTIFUNGALS FOR DERMATOLOGICAL USE
D: DERMATOLOGICALS
G01AX12: Ciclopirox
G01AX: Other antiinfectives and antiseptics
G01A: ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01: GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G: GENITO URINARY SYSTEM AND SEX HORMONES
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 207.27
Logarithm of the Partition Coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
ADMET Property
Half-life
The concentration or amount of drug in body reduced by one-half in 1.7 hours [3]
Metabolism
The drug is metabolized via the glucuronidation []
Chemical Identifiers
Formula
C12H17NO2
IUPAC Name
6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
Canonical SMILES
CC1=CC(=O)N(C(=C1)C2CCCCC2)O
InChI
InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
InChIKey
SCKYRAXSEDYPSA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
2749
ChEBI ID
CHEBI:453011
CAS Number
29342-05-0
UNII
19W019ZDRJ
DrugBank ID
DB01188
TTD ID
D07GRH
VARIDT ID
DR00986
ACDINA ID
D00945
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HIF-prolyl hydroxylase (HPH) TTJQFBG NOUNIPROTAC Modulator [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [6]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Gene/Protein Processing [7]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Protein Interaction/Cellular Processes [8]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Protein Interaction/Cellular Processes [9]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Cutaneous candidiasis
ICD Disease Classification 1F23.14
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
HIF-prolyl hydroxylase (HPH) DTT NO-GeName 7.70E-01 4.40E-03 0.02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 150 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 1.0272 4.3728 0.9183 33.7803
JK1 CTRP2 2.8156 5.8319 2.5764 22.3406
JM1 CTRP2 -0.0733 2.9134 -0.1032 40.8441
GA-10 CTRP2 -2.1171 1.5514 -2.1421 54.2741
EoL-1 CTRP2 -1.5356 0.8012 -1.5373 50.4984
KE-37 CTRP2 -1.2656 0.2142 -1.2657 48.7005
ST486 CTRP2 -1.0855 2.4282 -1.1222 47.5464
Hs 611.T CTRP2 -1.0668 2.5252 -1.1085 47.429
Daudi CTRP2 -0.9048 3.2022 -0.9934 46.4294
SU-DHL-8 CTRP2 -0.877 2.1875 -0.8964 46.1482
Granta-519 CTRP2 -0.7274 4.1083 -0.9215 45.4324
EB1 CTRP2 -0.6124 4.5896 -0.8812 44.8131
OCI-Ly19 CTRP2 -0.6021 6.2204 -1.258 45.2258
P12-Ichikawa CTRP2 -0.5134 1.2341 -0.5138 43.6902
NALM-6 CTRP2 -0.4446 1.2597 -0.445 43.232
697 CTRP2 -0.3329 2.1758 -0.3415 42.5112
SU-DHL-6 CTRP2 -0.2405 1.9901 -0.2447 41.8836
Peer CTRP2 -0.1258 1.3771 -0.1259 41.107
BL-70 CTRP2 -0.0698 3.5759 -0.151 40.9558
SUP-T11 CTRP2 -0.0336 1.3211 -0.0337 40.4929
SU-DHL-1 CTRP2 0.2157 1.2055 0.2157 38.8317
Reh CTRP2 0.2805 1.4966 0.2805 38.4001
SEM CTRP2 0.2821 1.8314 0.2817 38.3904
MJ CTRP2 0.3297 7.2522 -0.5594 40.1715
MOLT-16 CTRP2 0.3626 1.1273 0.3626 37.8529
NU-DHL-1 CTRP2 0.3926 3.4592 0.3448 37.8023
MOLT-13 CTRP2 0.4092 1.9215 0.4088 37.544
NU-DUL-1 CTRP2 0.4251 1.5853 0.425 37.4368
THP-1 CTRP2 0.4476 2.1068 0.4467 37.2898
Pfeiffer CTRP2 0.4673 3.5703 0.4139 37.3232
MHH-CALL-4 CTRP2 0.5036 2.0313 0.5031 36.915
ALL-SIL CTRP2 0.5543 2.8305 0.544 36.6097
KMS-18 CTRP2 0.5778 2.7554 0.5699 36.4452
CML-T1 CTRP2 0.5951 1.8813 0.595 36.3046
JVM-3 CTRP2 0.5982 2.4975 0.595 36.2937
DND-41 CTRP2 0.626 3.0402 0.6103 36.1494
MOLM-13 CTRP2 0.6287 3.4807 0.5893 36.2068
P31/FUJ CTRP2 0.6516 2.5238 0.6485 35.9378
HuT 78 CTRP2 0.6533 3.6707 0.6002 36.0867
OCI-AML-3 CTRP2 0.7042 3.1617 0.6855 35.6382
L-428 CTRP2 0.7354 5.453 0.4006 36.3726
EJM CTRP2 0.7892 5.5496 0.4364 36.0745
SUP-T1 CTRP2 0.8031 1.9398 0.803 34.9186
Kasumi-2 CTRP2 0.8031 3.148 0.7875 34.9696
EHEB CTRP2 0.8062 4.1177 0.7157 35.188
AML-193 CTRP2 0.825 3.767 0.7718 34.9452
TALL-1 [Human adult T-ALL] CTRP2 0.8855 3.3147 0.8649 34.437
RPMI-8402 CTRP2 0.9135 2.4977 0.9123 34.1868
KMS-34 CTRP2 0.9223 1.7908 0.9223 34.1243
SU-DHL-10 CTRP2 0.9567 3.5412 0.926 33.9964
JVM-2 CTRP2 0.9667 4.5413 0.8291 34.2723
RS4;11 CTRP2 0.9956 2.2274 0.9955 33.6361
SUP-HD1 CTRP2 0.9994 5.9517 0.5636 34.9528
PF-382 CTRP2 1.0099 3.0766 1.0011 33.5697
OCI-AML-2 CTRP2 1.0146 1.8491 1.0146 33.5094
Ri-1 CTRP2 1.0169 4.3759 0.9069 33.8523
Jurkat CTRP2 1.0322 2.5324 1.0313 33.3949
KE-97 CTRP2 1.0366 2.4381 1.0362 33.364
Raji CTRP2 1.0632 3.0938 1.0548 33.2134
BDCM CTRP2 1.0664 2.9096 1.0619 33.1792
RCH-ACV CTRP2 1.0673 2.5439 1.0664 33.1611
KMS-21-BM CTRP2 1.0745 2.3148 1.0743 33.1108
RPMI-8226 CTRP2 1.0911 3.7917 1.0481 33.1418
MOLT-3 CTRP2 1.0945 1.9048 1.0945 32.9771
Ci-1 CTRP2 1.1368 2.0368 1.1368 32.6952
MOTN-1 CTRP2 1.1814 4.2746 1.0952 32.6826
MHH-CALL-3 CTRP2 1.19 5.3107 0.9274 33.1906
A4/Fukuda CTRP2 1.1909 3.6933 1.1593 32.4397
KMS-28BM CTRP2 1.1977 4.7159 1.0496 32.7756
HT CTRP2 1.204 2.729 1.2027 32.2518
PL21 CTRP2 1.2067 2.7753 1.2051 32.2346
MOLM-6 CTRP2 1.2833 3.135 1.2774 31.7386
KHM-1B CTRP2 1.3255 2.8202 1.3242 31.4421
M-07e CTRP2 1.3285 3.2795 1.3198 31.4467
Namalwa CTRP2 1.3409 4.2966 1.2618 31.5985
NCO2 CTRP2 1.3435 3.1866 1.3374 31.3385
WSU-DLCL2 CTRP2 1.3653 3.6666 1.3415 31.252
HPB-ALL CTRP2 1.3872 4.4664 1.2896 31.3519
SUP-B15 CTRP2 1.3952 3.4163 1.3836 31.0123
MV4-11 CTRP2 1.3974 2.6288 1.3971 30.96
JeKo-1 CTRP2 1.4247 3.6481 1.4039 30.8465
P3HR-1 CTRP2 1.4393 5.8406 1.0729 31.8824
EM-2 CTRP2 1.4735 3.7007 1.4514 30.5255
KMS-27 CTRP2 1.6013 3.4989 1.5913 29.634
CA46 CTRP2 1.6313 6.2654 1.1661 30.9436
BV-173 CTRP2 1.6462 3.1248 1.6442 29.308
KO52 CTRP2 1.6694 3.8644 1.6447 29.2296
NCI-H929 CTRP2 1.6738 2.7512 1.6737 29.1178
RPMI-6666 CTRP2 1.7229 2.7552 1.7228 28.7906
DEL CTRP2 1.7262 3.024 1.7254 28.7713
KMS-12-BM CTRP2 1.7363 2.8609 1.7361 28.7021
L-540 CTRP2 1.7419 2.5507 1.7419 28.664
DB CTRP2 1.7534 3.9638 1.7255 28.6808
OCI-Ly10 CTRP2 1.7767 6.5458 1.241 30.2242
SUP-M2 CTRP2 1.7977 3.1743 1.7963 28.2967
SU-DHL-4 CTRP2 1.8056 4.2951 1.753 28.4161
Ki-JK CTRP2 1.8824 4.287 1.8346 27.8884
RL CTRP2 1.9323 5.4257 1.7092 28.1535
Mono-Mac-1 CTRP2 1.9618 4.643 1.8787 27.4796
MOLP-8 CTRP2 1.9632 3.5279 1.9586 27.2051
SKM-1 CTRP2 1.9647 2.802 1.9647 27.1793
OCI-Ly3 CTRP2 1.9767 4.6813 1.8895 27.394
NB4 CTRP2 2.0452 2.8091 2.0451 26.6435
KMS-20 CTRP2 2.091 4.7134 2.0071 26.6216
SK-MM-2 CTRP2 2.1222 5.8019 1.8276 27.1398
LP-1 CTRP2 2.1383 5.4711 1.9233 26.7576
L-363 CTRP2 2.1402 3.978 2.1246 26.0627
Mino CTRP2 2.2041 3.831 2.1959 25.612
SR CTRP2 2.2485 3.6307 2.2455 25.299
HD-MY-Z CTRP2 2.2497 4.2465 2.2222 25.3732
A3/Kawakami CTRP2 2.2774 3.0121 2.2774 25.0965
KMS-26 CTRP2 2.2921 3.4071 2.2914 25.0007
HEL CTRP2 2.319 3.0259 2.319 24.8189
OPM-2 CTRP2 2.3226 5.0376 2.2067 25.1893
AMO1 CTRP2 2.3259 4.0485 2.3123 24.8186
SET-2 CTRP2 2.3286 3.2904 2.3284 24.7559
Ku812 CTRP2 2.3632 3.7458 2.3596 24.5364
Karpas-422 CTRP2 2.3632 3.7533 2.3594 24.5372
MM1.S CTRP2 2.432 4.5292 2.3896 24.2093
KCL-22 CTRP2 2.4346 6.2723 2.0404 25.4193
JURL-MK1 CTRP2 2.4703 4.2049 2.4534 23.8677
JJN-3 CTRP2 2.4734 5.7672 2.2193 24.668
SIG-M5 CTRP2 2.474 2.9623 2.474 23.7867
HH [Human lymphoma] CTRP2 2.4997 5.9964 2.189 24.693
L-1236 CTRP2 2.521 6.6691 2.0121 25.2536
CMK CTRP2 2.5889 2.9705 2.5889 23.0212
HEL 92.1.7 CTRP2 2.5894 3.0278 2.5894 23.0178
Kasumi-1 CTRP2 2.5897 4.3663 2.5674 23.0905
LAMA-84 CTRP2 2.6034 4.1977 2.5908 22.9666
OCI-M1 CTRP2 2.6034 3.0991 2.6034 22.9243
Karpas-299 CTRP2 2.6057 4.9461 2.5245 23.1845
HL-60 CTRP2 2.6187 4.4091 2.5947 22.9028
ME1 CTRP2 2.6867 3.4383 2.6866 22.3699
TF-1 CTRP2 2.731 4.5859 2.6983 22.1846
GDM-1 CTRP2 2.7395 4.6546 2.701 22.1472
OCI-AML-5 CTRP2 2.7407 3.3123 2.7407 22.0094
KMM-1 CTRP2 2.8618 5.0269 2.7867 21.4578
U-937 CTRP2 3.0509 4.311 3.0447 19.9636
MOLP-2 CTRP2 3.059 6.2945 2.7148 21.0998
U266B1 CTRP2 3.121 6.2824 2.786 20.6548
HDLM-2 CTRP2 3.1232 8.1039 2.1278 23.0655
K-562 CTRP2 3.19 5.6207 3.0339 19.5546
MOLM-16 CTRP2 3.2156 4.39 3.2103 18.8635
KM-H2 CTRP2 3.443 7.3777 2.7557 19.8271
F-36P CTRP2 3.5023 7.3859 2.8157 19.4334
KYO-1 CTRP2 3.5846 5.0346 3.5536 16.4922
MC116 CTRP2 3.6378 4.0235 3.6378 16.0332
KMS-11 CTRP2 3.9913 6.9778 3.4941 15.484
REC-1 CTRP2 4.8332 6.898 4.4206 9.5932
Karpas-620 CTRP2 6.4108 8.2614 5.2245 2.8004
⏷ Show the Full List of 150 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.8103 5.0689 1.6487 28.7545
TE8 CTRP2 4.7718 8.0015 3.8743 11.9163
TE-5 CTRP2 2.3961 4.8249 2.3174 24.5719
OE21 CTRP2 3.1611 6.0795 2.8881 20.1643
KYSE-30 CTRP2 3.2305 4.4794 3.2225 18.7735
TE-14 CTRP2 3.2342 6.3647 2.8844 19.9567
KYSE-70 CTRP2 3.4678 9.2568 1.9901 22.6132
OE33 CTRP2 3.5126 6.6811 3.0845 18.397
TE-4 CTRP2 3.7946 6.828 3.3379 16.634
TE-9 CTRP2 3.8085 7.0863 3.2575 16.898
TE-1 CTRP2 3.813 9.6845 2.1436 21.1329
TE-11 CTRP2 3.9542 6.472 3.6336 15.0675
KYSE-510 CTRP2 4.4524 8.1672 3.4775 14.3114
COLO 680N CTRP2 4.6829 10.0657 2.8108 16.4083
KYSE-520 CTRP2 4.705 10.4754 2.6331 17.0566
KYSE-140 CTRP2 4.9132 10.3878 2.8705 15.6347
KYSE-450 CTRP2 4.9466 8.275 3.9204 11.2992
EC-GI-10 CTRP2 5.0688 6.9442 4.6477 8.0734
OE19 CTRP2 5.2767 7.7758 4.478 8.2329
TE-10 CTRP2 5.7141 10.3522 3.6094 10.8776
KYSE-150 CTRP2 6.2196 11.077 3.6725 9.6215
TE-6 CTRP2 6.3064 11.4448 3.5593 9.9281
KYSE-180 CTRP2 7.3858 13.3899 3.4207 8.6477
KYSE-410 CTRP2 7.6276 14.5655 3.0204 9.8522
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.9901 9.3156 3.4643 13.0566
Capan-2 CTRP2 1.9384 4.0765 1.9102 27.4493
L3.3 CTRP2 2.0842 8.7625 0.765 30.724
Panc 03.27 CTRP2 2.2082 3.0947 2.2082 25.5572
DAN-G CTRP2 2.4005 4.693 2.3388 24.4845
MIA PaCa-2 CTRP2 2.4077 6.7297 1.8693 26.1036
PSN1 CTRP2 2.6371 5.215 2.5151 23.1165
PaTu 8988s CTRP2 2.8915 6.9211 2.3297 23.0003
PK-59 CTRP2 3.112 7.3008 2.4308 21.9842
PaTu 8988t CTRP2 3.1767 6.532 2.7692 20.549
SW1990 CTRP2 3.2031 9.2229 1.7349 24.2533
YAPC CTRP2 3.3937 7.9864 2.4606 21.0737
Capan-1 CTRP2 3.3984 5.4022 3.3033 17.953
HuP-T4 CTRP2 3.4599 5.0303 3.4225 17.3444
KP-4 CTRP2 3.4929 5.3569 3.4129 17.2711
HPAF-II CTRP2 3.5039 6.713 3.0643 18.4974
SNU-213 CTRP2 3.6222 6.6193 3.2243 17.5579
Panc 10.05 CTRP2 3.7879 7.686 2.9983 17.9449
AsPC-1 CTRP2 3.8156 7.2808 3.1902 17.1336
QGP-1 CTRP2 4.0763 9.548 2.4682 19.2307
HuP-T3 CTRP2 4.1727 6.6911 3.7947 13.8317
BxPC-3 CTRP2 4.6512 8.1254 3.6968 12.9313
TCC-Pan2 CTRP2 4.679 10.1054 2.7878 16.5083
Panc 04.03 CTRP2 4.9676 8.357 3.9022 11.3226
CFPAC-1 CTRP2 5.0636 16.3504 0.0529 24.9839
KP-3 CTRP2 5.317 10.1933 3.3364 12.8456
Panc 08.13 CTRP2 5.4333 11.2788 2.902 14.3587
HPAC CTRP2 5.4828 11.1469 3.0112 13.8134
PK-45H CTRP2 5.9982 11.8151 3.1205 12.3179
SU.86.86 CTRP2 6.1198 9.6011 4.3285 7.0675
Panc 05.04 CTRP2 6.1365 11.1882 3.5488 10.2921
Panc 02.03 CTRP2 6.4579 11.1462 3.8294 17.4124
SNU-410 CTRP2 6.4834 12.1 3.3742 10.3641
SUIT-2 CTRP2 6.5899 10.3309 4.337 6.1891
Hs 766T CTRP2 7.0138 12.345 3.661 8.2735
KP-2 CTRP2 7.556 13.4632 3.5068 8.0401
PaTu 8902 CTRP2 10.6882 30.3905 -2.509 21.5933
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.2174 9.7653 3.4566 12.5719
WM266-4 CTRP2 2.269 4.8083 2.1841 25.4396
MeWo CTRP2 2.6018 5.3613 2.4494 23.4573
LOX-IMVI CTRP2 2.6978 4.1078 2.6909 22.3185
SK-MEL-28 CTRP2 2.7808 11.5338 0.2628 30.0784
IGR-1 CTRP2 2.8914 12.1154 0.1014 30.2037
SK-MEL-5 CTRP2 2.9309 6.4539 2.5265 22.1683
G-361 CTRP2 2.9639 7.4166 2.2287 23.1552
WT2-iPS CTRP2 3.0226 5.9243 2.7786 20.9811
IPC-298 CTRP2 3.0595 8.1561 2.0396 23.5674
A-375 CTRP2 3.2018 5.396 3.0922 19.3129
Hs 294T CTRP2 3.2184 5.9461 2.9865 19.6353
COLO 800 CTRP2 3.4251 7.8654 2.5431 20.677
SK-MEL-24 CTRP2 3.5198 8.2459 2.4842 20.6369
Mel Ho CTRP2 3.5755 7.6966 2.7702 19.4007
Hs 944.T CTRP2 3.6498 6.5406 3.2806 17.2684
WM88 CTRP2 3.7076 9.2589 2.2322 21.0788
CJM [Human melanoma] CTRP2 3.7777 5.5385 3.6882 15.4076
SK-MEL-3 CTRP2 3.9139 7.1265 3.3548 16.2317
RPMI-7951 CTRP2 3.9359 9.8068 2.209 20.5716
A101D CTRP2 4.0203 7.593 3.2807 16.2226
HMCB CTRP2 4.0417 7.3503 3.4023 15.6949
A2058 CTRP2 4.1053 7.781 3.2905 15.9558
SK-MEL-1 CTRP2 4.1462 6.2933 3.8999 13.5179
UACC-257 CTRP2 4.1998 9.2321 2.7372 17.8777
IGR-39 CTRP2 4.7802 7.3263 4.1847 10.6576
SK-MEL-30 CTRP2 4.7908 10.8739 2.5192 17.3015
COLO 829 CTRP2 4.8747 8.4376 3.7734 12.0703
WM793 CTRP2 4.9012 9.9689 3.0636 14.8882
UACC-62 CTRP2 5.1838 9.5749 3.5191 12.3905
WM1799 CTRP2 5.2286 10.8312 2.9412 14.644
Mel JuSo CTRP2 5.3057 11.3106 2.7729 15.1485
K029AX CTRP2 5.3443 7.693 4.5828 7.6432
COLO 792 CTRP2 5.356 8.7849 4.0653 9.7491
WM983B CTRP2 5.4451 9.8983 3.5978 11.4913
Hs 895.T CTRP2 5.8175 10.9721 3.389 11.5789
WM115 CTRP2 5.8773 11.8221 3.0152 12.9846
IGR-37 CTRP2 6.0665 12.2149 2.9776 12.762
SK-MEL-31 CTRP2 6.2641 22.4208 -1.9614 27.4146
MDA-MB-435S CTRP2 6.3293 10.6485 3.9752 8.1576
RVH-421 CTRP2 6.3899 11.2357 3.7308 9.0643
HT-144 CTRP2 6.873 12.5227 3.4672 9.2988
SK-MEL-2 CTRP2 7.5508 8.7025 5.6665 0.1918
Hs 934.T CTRP2 7.8019 16.6625 2.1194 12.9835
Hs 936.T CTRP2 7.9048 13.7992 3.5865 7.2113
Hs 839.T CTRP2 8.0282 16.4354 2.3951 11.6096
Hs 852.T CTRP2 8.0485 9.8926 5.425 0.4912
Hs 688(A).T CTRP2 8.099 20.2165 0.5893 17.6286
Hs 940.T CTRP2 8.3659 17.3817 2.1746 11.8973
Malme-3M CTRP2 8.8824 11.2412 5.2628 0.4912
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 2.4847 5.6083 2.2694 24.4564
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiMa CTRP2 0.7568 3.8068 0.6966 35.4207
CHP-126 CTRP2 0.8533 2.255 0.8529 34.5853
MHH-NB-11 CTRP2 0.9354 2.6721 0.9329 34.0452
CHP-212 CTRP2 1.8226 6.5148 1.3004 29.881
Kelly CTRP2 2.105 4.2622 2.0701 26.3621
SK-N-BE(2) CTRP2 2.1322 5.2803 1.9566 26.6624
SK-N-SH CTRP2 2.1843 3.7882 2.177 25.7411
NH-6 CTRP2 2.5517 4.4432 2.5225 23.3669
NB1 CTRP2 2.5774 4.5339 2.5418 23.2173
SK-N-DZ CTRP2 2.8262 5.1995 2.7216 21.7969
KP-N-SI9s CTRP2 2.9276 5.1365 2.8409 21.0597
SK-N-AS CTRP2 3.7918 10.3272 1.824 22.3569
SK-N-FI CTRP2 3.8875 7.9084 3.0099 17.6294
KP-N-YN CTRP2 4.3225 7.4276 3.6659 13.9098
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 1.3248 3.9046 1.2833 31.5808
SNU-478 CTRP2 2.0843 4.6104 2.0132 26.6227
SNU-1196 CTRP2 2.1471 8.2509 1.036 29.6974
SNU-245 CTRP2 3.516 5.7938 3.3493 17.4221
SNU-1079 CTRP2 3.9032 8.1172 2.9371 17.8683
SNU-869 CTRP2 4.1149 7.5744 3.3875 15.5527
HuH-28 CTRP2 4.3125 5.9819 4.171 12.0315
SNU-308 CTRP2 7.3573 11.3439 4.3928 4.7781
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 0.7235 2.9357 0.7133 35.4823
SK-ES-1 CTRP2 1.5273 3.0363 1.5254 30.1001
MHH-ES-1 CTRP2 2.0041 4.1858 1.9707 27.0289
HOS CTRP2 2.0205 2.8281 2.0205 26.8078
SK-N-MC CTRP2 2.0652 2.9019 2.0652 26.5102
TC71 CTRP2 2.957 4.4032 2.945 20.6089
SaOS-2 CTRP2 3.9202 9.0578 2.5377 19.365
SJSA-1 CTRP2 4.4851 8.62 3.3038 14.921
CAL-78 CTRP2 5.3432 8.2062 4.3351 8.6631
MG-63 CTRP2 5.464 9.3991 3.8618 10.3558
SW1353 CTRP2 5.589 10.6322 3.3608 12.1641
U2OS CTRP2 6.0366 12.4636 2.8283 13.4183
Hs 888.T CTRP2 7.7755 27.3175 -3.1861 27.1882
Hs 822.T CTRP2 7.8485 18.3912 1.3025 15.7621
G-292 clone A141B1 CTRP2 8.5467 10.4279 5.4282 0.2988
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2218 CTRP2 0.3955 2.1486 0.3942 37.638
SK-BR-3 CTRP2 0.5923 11.2901 -1.8537 41.2214
Hs 578Bst CTRP2 0.7171 2.4441 -2.5014 0.3728
MDA-MB-453 CTRP2 1.2238 5.2965 0.9673 32.9487
AU565 CTRP2 1.5107 13.4037 -6.9639 22.299
HCC1954 CTRP2 1.9543 4.8764 1.8369 27.646
HCC1419 CTRP2 1.9921 4.869 1.8786 27.3815
MCF-7 CTRP2 1.9972 7.3499 1.213 29.6053
MDA-MB-468 CTRP2 2.2228 4.6716 2.1528 25.6968
CAL-85-1 CTRP2 2.2245 7.3436 1.4604 28.075
CAMA-1 CTRP2 2.269 5.6936 2.0144 26.027
CAL-51 CTRP2 2.3627 5.3697 2.1885 25.1245
MDA-MB-361 CTRP2 2.4385 5.3129 2.282 24.5584
HCC1500 CTRP2 2.4915 3.4595 2.4912 23.6711
HCC38 CTRP2 2.5303 5.567 2.3284 24.1063
CAL-148 CTRP2 2.586 4.7639 2.5273 23.2388
DU4475 CTRP2 2.7358 7.5534 1.9329 24.8904
MDA-MB-231 CTRP2 3.5502 6.6011 3.1523 18.0355
BT-474 CTRP2 3.7898 7.7403 2.9779 18.0177
HCC1806 CTRP2 3.9781 7.9568 3.0835 17.1006
HCC1428 CTRP2 4.7703 9.3875 3.2205 14.5616
HMC-1-8 CTRP2 5.024 10.7369 2.8016 15.6574
BT-549 CTRP2 5.0733 10.3552 3.0344 14.6138
T-47D CTRP2 5.4194 11.5957 2.7321 15.0663
JIMT-1 CTRP2 5.8425 11.7852 3.004 13.0994
HCC1143 CTRP2 5.8821 11.3404 3.26 11.979
HCC202 CTRP2 6.0207 13.004 2.5448 14.5668
HCC1937 CTRP2 6.0703 11.38 3.3981 11.0415
Hs 578T CTRP2 6.2078 8.9979 4.7015 5.3369
HDQ-P1 CTRP2 6.6675 13.2063 2.9686 11.6718
BT-20 CTRP2 6.7663 13.6817 2.8095 12.1256
HCC1395 CTRP2 6.884 10.3095 4.5646 4.7744
KPL-1 CTRP2 7.2712 8.1933 5.7424 0.1464
ZR-75-1 CTRP2 7.6352 13.6249 3.4841 8.0105
BT 239 CTRP2 -2.2848 -1.8505 -2.2848 55.4902
BT 145 CTRP2 -0.3558 1.951 -0.3605 42.6529
BT 271 CTRP2 -0.2445 3.5101 -0.3286 42.112
BT164 CTRP2 -0.1893 3.0442 -0.2313 41.6457
BT 112 CTRP2 0.1406 4.5074 -0.0534 39.859
BT 330 CTRP2 0.1579 3.7131 0.075 39.458
BT 231 CTRP2 1.1185 4.4494 1.0052 33.1884
BT 131 CTRP2 1.1339 4.7555 0.9743 33.2352
BT 286 CTRP2 1.3293 8.1649 0.1962 34.7848
BT 172 CTRP2 1.3696 5.7818 1.0119 32.3109
BT 504 CTRP2 1.6362 6.0472 1.2328 30.7114
BT 428 CTRP2 1.6823 4.1042 1.6409 29.1995
BT 245 CTRP2 2.2997 5.1984 2.1537 25.4455
BT 228 CTRP2 2.371 7.8574 1.4272 27.7351
BT 224 CTRP2 2.9324 5.4109 2.7978 21.1939
BT147 CTRP2 3.1655 6.6571 2.7162 20.7768
BT 333 CTRP2 3.2582 8.741 2.0013 23.1469
BT 416 CTRP2 3.3005 4.9812 3.2593 18.4191
BT 179 CTRP2 3.4305 6.1597 3.1594 18.366
BT 248 CTRP2 3.4317 10.0336 1.6024 24.0924
BT 422 CTRP2 4.035 9.1641 2.6045 18.8118
BT 444 CTRP2 4.4664 9.3537 2.9427 16.406
BT 232 CTRP2 4.4866 11.0384 2.1544 19.4119
BT 482 CTRP2 4.8208 9.9685 2.9882 15.3776
BT 340 CTRP2 5.6502 16.4567 0.5062 22.4146
BT 359 CTRP2 5.6999 15.1088 1.222 20.0312
BT 216 CTRP2 6.0735 9.334 4.4238 6.7558
BT 328 CTRP2 6.1984 10.5497 3.9188 8.6356
BT 187 CTRP2 6.5889 13.1467 2.9361 11.9433
BT 440 CTRP2 6.6813 17.5342 0.8212 19.3992
BT 139 CTRP2 6.9977 13.5973 3.03 10.8473
BT 320 CTRP2 7.9705 8.9445 5.7343 0.038
BT 159 CTRP2 9.1023 18.1936 2.2904 10.4137
BT 498 CTRP2 10.9766 27.5736 -0.9386 17.6191
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.9616 6.4718 2.5543 21.9747
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF268 CTRP2 1.581 6.1974 1.1307 31.2237
D283 Med CTRP2 1.8347 4.4784 1.764 28.2836
SF539 CTRP2 2.0068 5.8546 1.6884 27.986
KNS-81 CTRP2 2.2246 6.8393 1.6344 27.4839
Daoy CTRP2 2.3035 4.9686 2.1973 25.2832
GMS-10 CTRP2 2.3545 7.1895 1.6555 27.0098
AM-38 CTRP2 2.7167 6.0868 2.4011 23.2699
GOS-3 CTRP2 2.8314 6.1743 2.5017 22.5586
SNU-738 CTRP2 2.9572 7.0582 2.3526 22.7226
GB-1 CTRP2 3.0749 6.92 2.5284 21.7331
A-172 CTRP2 3.1598 7.8636 2.2637 22.4632
SNU-466 CTRP2 3.1701 4.0389 3.1695 19.151
42-MG-BA CTRP2 3.4564 7.295 2.8016 19.6165
SNU-626 CTRP2 3.6406 5.7045 3.5055 16.4808
KNS-60 CTRP2 3.7934 7.9876 2.8783 18.3906
YH-13 CTRP2 3.7949 6.8917 3.3152 16.7185
LN-18 CTRP2 3.8521 7.8527 2.9964 17.7767
DK-MG CTRP2 4.0492 7.0006 3.5475 15.118
Hs 683 CTRP2 4.0803 8.1536 3.104 16.7497
SF295 CTRP2 4.137 7.0397 3.6261 14.5723
SF126 CTRP2 4.1451 7.1609 3.5874 14.698
8-MG-BA CTRP2 4.1871 6.7663 3.783 13.8349
M059K CTRP2 4.3476 8.1198 3.3923 14.9186
U-118MG CTRP2 4.5024 9.4511 2.9317 16.3617
SW1783 CTRP2 4.5396 7.1394 4.013 11.9728
SNU-201 CTRP2 4.636 6.8108 4.2467 10.8064
Becker CTRP2 4.7243 8.4476 3.621 13.0543
T98G CTRP2 4.766 11.8034 2.0406 19.1797
KNS-42 CTRP2 4.8891 8.1081 3.9418 11.3529
CAS-1 CTRP2 5.0803 11.9222 2.2679 17.6118
NMC-G1 CTRP2 5.0982 12.5005 1.9975 18.5868
TM-31 CTRP2 5.4013 10.0595 3.4785 12.0783
GaMG CTRP2 5.4439 13.5557 1.7773 18.6384
YKG-1 CTRP2 5.6977 9.1505 4.1937 8.4741
ONS-76 CTRP2 5.7416 9.9537 3.832 9.8951
KALS-1 CTRP2 5.8138 11.6715 3.0364 13.0265
U-251MG CTRP2 5.8138 11.3618 3.1911 12.3976
U-87MG ATCC CTRP2 6.2315 12.0622 3.19 11.5842
SNU-1105 CTRP2 6.4645 11.2828 3.7666 8.781
KG-1-C CTRP2 6.4786 8.048 5.3773 2.0685
SNB-75 CTRP2 6.9882 15.1172 2.2685 13.8124
CCF-STTG1 CTRP2 7.0304 13.6138 3.0467 10.7251
SNU-489 CTRP2 7.8625 15.5697 2.6988 10.726
SW1088 CTRP2 7.8885 13.7657 3.5915 7.2148
LN-229 CTRP2 8.0198 14.0738 3.5327 7.2599
DBTRG-05MG CTRP2 8.1148 13.049 4.0805 5.0022
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2 0.4729 4.7185 0.2679 37.722
JHUEM-2 CTRP2 1.3165 3.8586 1.2783 31.625
ESS-1 CTRP2 2.1642 3.3711 2.1632 25.8537
JHUEM-3 CTRP2 2.2851 5.8857 1.984 26.0823
HEC-1-B CTRP2 2.4092 5.241 2.2642 24.7135
HEC-265 CTRP2 2.5922 4.3732 2.5696 23.075
HEC-50B CTRP2 2.6097 5.779 2.365 23.7287
AN3-CA CTRP2 2.6324 5.0001 2.5451 23.0278
JHUEM-1 CTRP2 2.7496 5.2212 2.6354 22.3404
JHUEM-7 CTRP2 3.2545 7.95 2.3289 21.9546
HEC-59 CTRP2 3.8344 7.8395 2.9835 17.8748
MFE-296 CTRP2 4.2897 8.7508 3.0486 16.4264
EFE-184 CTRP2 4.2947 8.3721 3.2257 15.7138
HEC-251 CTRP2 4.3769 10.0994 2.5018 18.3528
RL95-2 CTRP2 4.8286 9.1733 3.3791 13.7815
HEC-1-A CTRP2 4.9222 9.5376 3.2927 13.9128
HEC-6 CTRP2 5.3729 8.7673 4.0895 9.6111
MFE-319 CTRP2 5.4264 9.6117 3.7227 11.0145
HEC-108 CTRP2 5.7834 12.4332 2.63 14.7104
EN CTRP2 7.13 12.9012 3.4733 8.8459
KLE CTRP2 7.222 10.9573 4.4865 4.5931
Ishikawa (Heraklio) 02 ER- CTRP2 2.3824 6.8238 1.8109 26.3854
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 CTRP2 2.7147 5.449 2.5542 22.7342
786-O CTRP2 2.822 5.4847 2.6632 22.0137
TUHR14TKB CTRP2 3.0066 12.6613 -0.0431 30.2664
SNU-1272 CTRP2 3.2399 5.1384 3.1751 18.9036
UO-31 CTRP2 3.4625 8.2876 2.4069 21.0848
BFTC-909 CTRP2 3.7287 7.7467 2.9111 18.4412
769-P CTRP2 3.7951 6.0673 3.5834 15.7263
KMRC-1 CTRP2 4.1116 6.7851 3.6948 14.383
ACHN CTRP2 4.3908 7.4988 3.7072 13.5653
KMRC-20 CTRP2 4.5674 9.6098 2.9191 16.2538
TUHR4TKB CTRP2 4.905 6.2573 4.7369 8.189
KMRC-3 CTRP2 5.2064 9.3633 3.6436 11.8273
VMRC-RCZ CTRP2 5.7066 7.9814 4.7817 5.9979
VMRC-RCW CTRP2 6.1776 8.1853 5.0828 3.7922
Caki-1 CTRP2 6.3659 9.1151 4.768 4.7758
RCC10RGB CTRP2 7.3512 10.0362 5.0039 2.402
OS-RC-2 CTRP2 7.834 9.5808 5.4526 0.5302
KMRC-2 CTRP2 7.9332 13.9764 3.5207 7.4295
Caki-2 CTRP2 8.3155 13.927 3.7969 5.8379
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320 CTRP2 0.759 5.7554 0.3526 36.4171
NCI-H747 CTRP2 1.1575 3.4612 1.1379 32.6222
SK-CO-1 CTRP2 1.3814 7.1808 0.6054 33.4943
SNU-81 CTRP2 1.5252 4.6623 1.4095 30.4949
LS123 CTRP2 1.6854 4.6889 1.5771 29.4042
LS513 CTRP2 1.6981 3.7606 1.68 29.0159
SW620 CTRP2 1.8496 5.2612 1.6541 28.6084
SW48 CTRP2 1.932 5.5335 1.6849 28.2373
HCT 15 CTRP2 2.0021 6.7612 1.4183 28.9149
LS1034 CTRP2 2.0031 4.0137 1.9812 26.9972
HT-55 CTRP2 2.0039 8.2533 0.8828 30.6224
SNU-1033 CTRP2 2.0113 6.2555 1.5836 28.3287
SNU-61 CTRP2 2.0528 5.1528 1.8953 27.1282
RKO CTRP2 2.0537 5.7933 1.7552 27.6069
T84 CTRP2 2.2004 5.3694 2.0125 26.2515
HT-29 CTRP2 2.2439 9.7549 0.5156 30.9546
CW-2 CTRP2 2.3782 4.1993 2.3586 24.4903
SNU-C1 CTRP2 2.3814 5.6497 2.1473 25.2089
SW1417 CTRP2 2.505 5.5058 2.3144 24.2348
SW1463 CTRP2 2.5347 4.0418 2.5266 23.4091
RCM-1 [Human ESC] CTRP2 2.5798 5.0953 2.4738 23.4429
SNU-407 CTRP2 2.8703 6.5128 2.442 22.6563
HCT 116 CTRP2 2.9866 9.7679 1.2726 26.4403
HCC-56 CTRP2 3.1757 5.334 3.0751 19.4556
LS180 CTRP2 3.3078 8.7417 2.0524 22.8238
COLO 678 CTRP2 3.3086 9.1841 1.86 23.5174
NCI-H716 CTRP2 3.4997 6.661 3.0774 18.4613
CL-11 CTRP2 3.5275 6.8036 3.0584 18.4505
HT115 CTRP2 3.8552 7.2613 3.24 16.8335
CCK-81 CTRP2 3.9315 7.7752 3.1118 17.1163
LoVo CTRP2 4.036 7.6497 3.2736 16.2076
NCI-H508 CTRP2 4.07 6.0301 3.8936 13.7702
GP2d CTRP2 4.1348 8.0117 3.2219 16.1449
MDST8 CTRP2 4.1629 6.849 3.7263 14.1183
SNU-C5 CTRP2 4.2805 7.9593 3.3946 15.0839
COLO201 CTRP2 4.3247 8.5488 3.176 15.834
C2BBe1 CTRP2 4.3672 11.042 2.0397 20.1272
KM12 CTRP2 4.4303 11.3727 1.9391 20.3453
DLD-1 CTRP2 4.7311 11.3294 2.241 18.5085
SNU-C2A CTRP2 4.846 9.6324 3.1747 14.5681
COLO205 CTRP2 4.8817 5.6119 4.8622 7.8118
SNU-C4 CTRP2 5.0133 7.4645 4.3615 9.3533
SNU-503 CTRP2 5.2172 10.8538 2.9198 14.7551
SW948 CTRP2 5.6979 9.7706 3.8852 9.7631
HCT 8 CTRP2 6.673 11.5045 3.8189 8.1975
OUMS-23 CTRP2 6.7532 10.1839 4.5316 5.1142
LS411N CTRP2 10.3638 21.5716 1.5179 11.3663
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-1 CTRP2 2.1636 7.2056 1.4436 28.3211
PLC/PRF/5 CTRP2 2.5152 5.0405 2.4132 23.8591
JHH-5 CTRP2 2.9806 5.6207 2.8062 21.0129
Li-7 CTRP2 3.1199 6.7769 2.6265 21.2404
HuH-6 CTRP2 3.6464 8.0282 2.708 19.4421
Hep 3B2.1-7 CTRP2 3.9887 10.0355 2.1542 20.6417
SNU-398 CTRP2 3.9899 7.1059 3.4438 15.6797
JHH-2 CTRP2 4.1994 9.3422 2.6857 18.0793
SNU-423 CTRP2 4.2553 8.0274 3.3389 15.369
JHH-4 CTRP2 4.402 6.5616 4.0882 12.0705
JHH-1 CTRP2 4.4727 7.7243 3.6948 28.2429
Hep-G2 CTRP2 4.5081 18.3392 -1.426 29.835
SNU-449 CTRP2 4.6919 8.4015 3.6103 13.1773
SNU-761 CTRP2 6.0461 10.9497 3.5931 10.2825
SNU-182 CTRP2 6.1139 10.6288 3.8098 9.2506
SNU-878 CTRP2 6.2293 8.7061 4.8643 4.6146
SNU-475 CTRP2 6.3185 8.7554 4.91 4.2649
SK-HEP-1 CTRP2 6.494 11.4836 3.6898 9.0464
JHH-6 CTRP2 7.0723 7.8577 5.7867 0.1306
HLF CTRP2 8.0608 9.8019 5.4646 0.461
SNU-387 CTRP2 8.3711 16.1064 2.7956 9.5946
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 140 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1915 CTRP2 -1.2119 0.754 -2.7421 4.6571
NCI-H1385 CTRP2 -0.9863 3.238 -1.0831 46.966
NCI-H2141 CTRP2 -0.3397 6.9538 -1.1908 43.9615
NCI-H2029 CTRP2 0.1406 6.0052 -0.3879 40.6023
DV-90 CTRP2 0.5797 5.2603 0.275 37.2981
NCI-H2405 CTRP2 0.7236 3.8536 0.6572 35.6611
NCI-H2081 CTRP2 0.7661 5.3018 0.4685 36.0692
NCI-H1694 CTRP2 0.8901 2.9814 0.8816 34.3669
NCI-H810 CTRP2 0.9148 5.9407 0.4743 35.5105
DMS 53 CTRP2 0.958 8.2198 -0.2222 37.0997
NCI-H146 CTRP2 1.1367 3.6829 1.1036 32.8054
COLO 668 CTRP2 1.1602 4.9537 0.9674 33.167
NCI-H524 CTRP2 1.1953 5.9594 0.7754 33.6392
COR-L95 CTRP2 1.2436 6.0595 0.801 33.3944
NCI-H1734 CTRP2 1.3549 3.5326 1.3375 31.3001
Sq-1 CTRP2 1.401 3.9868 1.3564 31.0838
NCI-H1105 CTRP2 1.468 4.4768 1.3744 30.8011
COR-L105 CTRP2 1.5557 8.0339 0.4881 33.2345
VMRC-LCD CTRP2 1.5712 4.5624 1.473 30.1301
DMS 79 CTRP2 1.7426 5.5286 1.4798 29.5451
HCC1588 CTRP2 1.7798 4.0705 1.7454 28.5267
Lu-65 CTRP2 1.7921 9.467 0.1679 33.3173
NCI-H1341 CTRP2 1.803 4.7891 1.6881 28.6444
SK-MES-1 CTRP2 1.8408 5.8882 1.4985 29.1633
NCI-H211 CTRP2 1.8531 5.4811 1.6109 28.7439
NCI-H69 CTRP2 1.8569 4.668 1.7634 28.213
NCI-H526 CTRP2 1.9699 3.6227 1.9633 27.1668
NCI-H1092 CTRP2 1.99 9.5103 0.3563 32.1863
Lu-99 CTRP2 2.0191 3.8981 2.0038 26.868
NCI-H1666 CTRP2 2.0242 5.0337 1.8859 27.2524
NCI-H1155 CTRP2 2.036 4.234 2.0002 26.8246
NCI-H661 CTRP2 2.0957 9.511 0.466 31.5519
NCI-H23 CTRP2 2.1973 4.5537 2.1395 25.8249
NCI-H292 CTRP2 2.216 5.493 2.003 26.2346
DMS 454 CTRP2 2.2171 5.3187 2.041 26.0993
SBC-5 CTRP2 2.222 4.9572 2.1116 25.8403
Calu-3 CTRP2 2.2437 4.5928 2.1843 25.521
SHP-77 CTRP2 2.247 4.6154 2.1852 25.5076
DMS 114 CTRP2 2.2679 4.8444 2.1778 25.4646
PC-14 CTRP2 2.325 5.1595 2.1881 25.2458
HARA [Human squamous cell lung carcinoma] CTRP2 2.3278 5.6783 2.0821 25.6057
NCI-H1581 CTRP2 2.4016 5.9538 2.0932 25.3355
NCI-H2171 CTRP2 2.4178 8.0918 1.3862 27.7302
NCI-H2228 CTRP2 2.4351 6.4397 1.9908 25.5922
HCC4006 CTRP2 2.464 3.4084 2.4638 23.854
NCI-H1184 CTRP2 2.5 6.4376 2.0622 25.1407
HCC78 CTRP2 2.5097 4.5016 2.4737 23.6696
NCI-H2087 CTRP2 2.5851 6.3062 2.1946 24.4097
NCI-H1568 CTRP2 2.5862 6.3607 2.1795 24.4602
NCI-H647 CTRP2 2.6279 6.4839 2.1871 24.3057
NCI-H209 CTRP2 2.6289 7.8226 1.7158 25.9718
DMS 273 CTRP2 2.7571 7.4775 1.9842 24.6446
NCI-H2122 CTRP2 2.7913 7.596 1.9761 24.5723
RERF-LC-A1 CTRP2 2.8579 6.3162 2.489 22.5241
HCC1438 CTRP2 2.8631 5.2158 2.7586 21.5508
NCI-H2286 CTRP2 2.9444 5.6267 2.7654 21.2702
SK-LU-1 CTRP2 3.1061 6.9438 2.5538 21.5482
NCI-H520 CTRP2 3.1882 5.9422 2.9547 19.8417
NCI-H1373 CTRP2 3.2204 6.4047 2.857 20.0978
EBC-1 CTRP2 3.2832 5.8171 3.0899 19.066
NCI-H2172 CTRP2 3.4114 5.53 3.2933 17.947
NCI-H1703 CTRP2 3.439 8.1115 2.4563 20.9644
NCI-H1563 CTRP2 3.4651 7.766 2.6257 20.2544
NCI-H2170 CTRP2 3.49 6.5304 3.1103 18.3677
NCI-H2106 CTRP2 3.5065 6.6145 3.1005 18.3555
NCI-H2110 CTRP2 3.5774 6.0991 3.337 17.2779
NCI-H460 CTRP2 3.7555 9.9542 1.9618 21.9525
LCLC-103H CTRP2 3.7633 7.0967 3.2052 17.2237
LK2 CTRP2 3.7717 6.9554 3.2669 16.9668
HCC2279 CTRP2 3.9369 10.4966 1.8865 21.7583
NCI-H889 CTRP2 3.9704 8.8529 2.681 18.6829
NCI-H841 CTRP2 3.9744 6.1554 3.7541 14.565
ChaGo-K-1 CTRP2 3.9886 9.3405 2.4771 19.4204
NCI-H2342 CTRP2 4.0006 9.6867 2.3288 19.9544
HCC15 CTRP2 4.0088 7.6815 3.2318 16.4432
RERF-LC-Ad2 CTRP2 4.0593 9.9521 2.2626 20.0557
NCI-H1944 CTRP2 4.0615 7.8558 3.2132 16.3735
LCLC-97TM1 CTRP2 4.0859 7.2548 3.4873 15.246
EPLC-272H CTRP2 4.1318 6.9633 3.65 14.4956
RERF-LC-MS CTRP2 4.1321 6.8796 3.6818 14.374
HOP-62 CTRP2 4.1527 12.0609 1.3438 23.1222
LXF 289 CTRP2 4.1677 6.7618 3.7637 13.963
NCI-H1339 CTRP2 4.1767 7.7243 3.3888 15.3813
LUDLU-1 CTRP2 4.1835 8.6056 3.008 16.8575
NCI-H1869 CTRP2 4.2075 10.0761 2.3489 19.3567
NCI-H650 CTRP2 4.25 10.6981 2.0935 20.2137
NCI-H446 CTRP2 4.365 8.2819 3.3375 15.0909
NCI-H1651 CTRP2 4.3761 9.8791 2.606 17.9509
NCI-H322 CTRP2 4.4144 9.2355 2.9474 16.5151
NCI-H1299 CTRP2 4.4464 8.4122 3.3604 14.7926
SW1271 CTRP2 4.4608 8.2033 3.4698 14.3207
KNS-62 CTRP2 4.517 10.4423 2.4715 18.1309
NCI-H2196 CTRP2 4.5281 9.6715 2.8518 16.6156
NCI-H1435 CTRP2 4.6035 9.4353 3.0372 15.6965
NCI-H2023 CTRP2 4.6049 8.4777 3.4887 13.882
A-549 CTRP2 4.6361 7.5565 3.9361 12.0173
NCI-H522 CTRP2 4.7613 22.9075 -3.4789 33.0185
NCI-H1395 CTRP2 4.7914 13.0777 1.4358 21.2878
NCI-H1623 CTRP2 4.9298 10.4529 2.854 15.6625
COLO 699 CTRP2 4.9491 10.0315 3.0778 14.7206
NCI-H1573 CTRP2 5.1023 7.3486 4.5038 8.5577
HCC95 CTRP2 5.1116 8.5147 3.9661 10.7193
NCI-H226 CTRP2 5.1909 8.6459 3.9783 10.4841
Calu-6 CTRP2 5.2152 13.1024 1.8026 19.0416
HOP-92 CTRP2 5.2537 10.057 3.3463 12.9437
HCC2108 CTRP2 5.2676 9.1617 3.799 11.0488
HCC1195 CTRP2 5.4311 8.8031 4.1257 9.3314
NCI-H1838 CTRP2 5.5142 11.4486 2.8886 14.2407
MOR/CPR CTRP2 5.517 13.2504 1.9929 17.696
NCI-H1650 CTRP2 5.628 10.1905 3.6149 11.0331
T3M-10 CTRP2 5.775 9.8494 3.9129 9.4889
CAL-12T CTRP2 5.8569 15.5781 1.1204 20.0459
LC-1/sq-SF CTRP2 5.8897 10.3103 3.7812 9.8075
NCI-H2030 CTRP2 6.0435 7.9157 5.108 3.9378
NCI-H1793 CTRP2 6.0681 10.7592 3.7067 9.7679
NCI-H838 CTRP2 6.0913 9.1295 4.5408 6.23
HCC366 CTRP2 6.248 11.2395 3.6145 9.8085
NCI-H727 CTRP2 6.2575 11.3114 3.5863 9.9077
NCI-H358 CTRP2 6.2831 13.4096 2.5587 14.0019
NCI-H2085 CTRP2 6.3288 13.1917 2.7049 13.3429
NCI-H2126 CTRP2 6.3331 9.4006 4.6004 5.5348
EKVX CTRP2 6.5054 12.3965 3.2439 10.8556
HCC1833 CTRP2 6.5269 11.7233 3.5963 9.3733
NCI-H196 CTRP2 6.595 12.6711 3.178 10.9607
NCI-H1792 CTRP2 6.6445 10.8987 4.0974 7.0923
NCI-H2444 CTRP2 6.6856 17.6058 0.789 19.4932
LOU-NH91 CTRP2 6.788 9.1829 5.0433 2.9707
RERF-LC-Ad1 CTRP2 6.8315 7.7474 5.725 0.3914
HCC44 CTRP2 7.1006 11.909 3.9389 6.9985
HCC827 CTRP2 7.1419 11.8254 4.0097 6.6452
NCI-H2291 CTRP2 7.3226 10.6585 4.6958 3.624
HCC2935 CTRP2 7.3268 12.334 3.8936 6.8331
NCI-H2009 CTRP2 7.4474 12.5524 3.8725 6.7375
NCI-H1355 CTRP2 7.5169 21.5043 -0.4952 21.7044
NCI-H441 CTRP2 8.0971 10.2725 5.2977 0.7814
HCC1171 CTRP2 8.4513 12.4762 4.5437 2.9039
NCI-H1755 CTRP2 8.4941 10.2896 5.4579 0.265
Calu-1 CTRP2 9.31 19.428 1.8396 11.7018
BEN CTRP2 12.1662 33.684 -3.0659 20.8317
Hs 888.Lu CTRP2 5.2894 10.7882 3.0173 14.2045
⏷ Show the Full List of 140 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 1.2302 4.1174 1.1644 32.291
H-STS CTRP2 1.4509 2.0885 1.4509 30.6025
SYO-1 CTRP2 3.081 6.0697 2.8034 20.713
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.9831 8.8548 1.6675 25.1088
COV434 CTRP2 -0.2568 6.1357 -0.8574 43.1352
OC 314 CTRP2 1.9032 4.4279 1.8423 27.7943
MCAS CTRP2 2.1741 5.5638 1.9415 26.5806
A2780 CTRP2 2.2024 4.9058 2.0986 25.948
Caov-3 CTRP2 2.3934 5.6057 2.1706 25.0897
OVK18 CTRP2 2.4521 5.3311 2.2932 24.4766
TOV-112D CTRP2 2.5212 4.5572 2.4807 23.6084
DOV13 CTRP2 2.5569 5.9208 2.2714 24.224
OV-90 CTRP2 2.628 3.8164 2.626 22.7671
OV7 CTRP2 2.7774 10.1079 0.9081 28.2045
IGROV-1 CTRP2 2.9729 7.4819 2.2136 23.1841
OAW42 CTRP2 3.2615 5.7926 3.0722 19.1965
OVCAR-8 CTRP2 3.275 6.2377 2.9671 19.5332
HEY A8 CTRP2 3.2804 6.4752 2.9002 19.7608
COV644 CTRP2 3.4459 10.8087 1.2582 25.2246
JHOC-5 CTRP2 3.5204 5.2552 3.4583 17.0263
SNU-8 CTRP2 3.7434 7.0963 3.1841 17.3599
TYK-nu CTRP2 3.8775 6.3281 3.5964 15.4312
JHOM-1 CTRP2 4.0094 8.6553 2.8094 18.084
OVCAR-5 CTRP2 4.0714 8.9701 2.7296 18.234
COV362 CTRP2 4.1596 10.1999 2.2438 19.8746
EFO-21 CTRP2 4.3016 6.7684 3.9052 13.047
OVTOKO CTRP2 4.3075 7.7485 3.514 14.5436
ES2 CTRP2 4.4795 9.6694 2.8058 16.9154
OAW28 CTRP2 4.5221 8.9163 3.2027 15.2332
OVCAR-4 CTRP2 4.7826 12.7172 1.6058 20.716
OV56 CTRP2 4.9122 6.4403 4.6819 8.3731
OVSAHO CTRP2 5.4132 11.7519 2.649 15.4079
SK-OV-3 CTRP2 5.4558 11.0866 3.0174 13.8457
JHOS-2 CTRP2 5.6691 10.2777 3.6074 10.9786
ONCO-DG-1 CTRP2 5.6721 11.8729 2.8144 14.2081
RMG-I CTRP2 6.8443 10.895 4.2492 6.1331
SNU-840 CTRP2 6.9236 12.2906 3.6204 8.5886
SNU-119 CTRP2 7.1373 11.6293 4.1021 6.2759
TOV-21G CTRP2 7.3623 9.8118 5.1126 2.2949
EFO-27 CTRP2 7.5426 13.3242 3.5649 7.8283
Kuramochi CTRP2 8.0167 15.0167 3.0766 9.0403
FU-OV-1 CTRP2 8.2276 9.939 5.4812 0.3055
OVISE CTRP2 13.5122 30.4442 -0.6358 13.8095
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 3.12 7.2801 2.447 21.9015
Aska-SS CTRP2 3.7035 6.8976 3.2147 17.3582
TE 617.T CTRP2 0.9681 4 0.9001 34.0417
TE 441.T CTRP2 1.1143 7.3289 0.2656 35.3571
A-204 CTRP2 1.6995 5.2456 1.4945 29.6364
Rh41 CTRP2 1.8037 4.913 1.669 28.7068
BT-16 CTRP2 1.9323 4.4673 1.8687 27.6097
G-401 CTRP2 2.0364 4.154 2.0067 26.8014
SK-LMS-1 CTRP2 2.3981 3.1923 2.3981 24.2924
BT-12 CTRP2 2.401 8.754 1.1018 28.7083
KYM-1 CTRP2 2.4091 3.9791 2.4003 24.2483
TTC-709 CTRP2 2.8113 5.7021 2.6032 22.2586
G-402 CTRP2 2.9675 6.5661 2.5308 22.0428
HT-1080 CTRP2 3.0511 7.1133 2.4341 22.1495
Tm87-16 CTRP2 3.3197 9.1042 1.9066 23.3196
SK-UT-1 CTRP2 3.9757 7.9717 3.0746 17.1417
SW982 CTRP2 3.997 6.594 3.639 14.9223
RD CTRP2 4.0082 10.9653 1.7333 22.1286
Hs 729.T CTRP2 4.4003 9.585 2.769 17.254
MES-SA CTRP2 5.0663 8.2773 4.0358 10.5413
RKN CTRP2 6.0688 10.6724 3.7507 9.5836
Rh18 CTRP2 6.1726 11.3375 3.504 10.4084
GCT CTRP2 6.2234 15.5195 1.4552 18.1802
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.9441 15.5216 1.2219 19.5307
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 1.8829 3.737 1.8708 27.7648
NCI-H2452 CTRP2 2.3449 6.7222 1.8035 26.5266
IST-Mes1 CTRP2 2.5082 4.2818 2.4882 23.6255
NCI-H28 CTRP2 2.7767 6.2498 2.4201 23.0181
ACC-MESO-1 CTRP2 2.7875 6.3829 2.3921 23.0862
MPP 89 CTRP2 3.5 11.0312 1.2074 25.2484
NCI-H2052 CTRP2 4.132 6.3971 3.8514 13.739
JL-1 CTRP2 5.2515 10.5927 3.0798 14.0342
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 1.7283 4.9903 1.5743 29.2735
VCaP CTRP2 2.0974 3.5439 2.0941 26.3066
22Rv1 CTRP2 2.5921 5.7311 2.3575 23.8102
PaCa-3 CTRP2 3.8661 5.7731 3.7354 14.9638
DU145 CTRP2 4.2392 8.0105 3.3298 15.447
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.9941 3.5039 1.9903 26.9961
A-253 CTRP2 2.3952 4.3599 2.3655 24.4113
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 0.9651 2.8418 0.9606 33.8541
GSS CTRP2 1.3859 2.8725 1.3845 31.0405
ECC10 CTRP2 1.4053 3.8908 1.3685 31.0293
SNU-601 CTRP2 1.6516 4.0164 1.6159 29.3849
SNU-5 CTRP2 1.8213 3.5124 1.8149 28.1563
SNU-1 CTRP2 2.2279 5.925 1.9114 26.5155
23132/87 CTRP2 2.3818 7.0121 1.7467 26.6107
HGC-27 CTRP2 2.4766 5.7336 2.231 24.6166
KATO III CTRP2 2.5129 5.2104 2.3819 23.9747
NUGC-3 CTRP2 2.631 5.754 2.3944 23.5586
SNU-216 CTRP2 2.6877 6.8623 2.1291 24.3324
NCI-N87 CTRP2 2.7716 5.5631 2.5917 22.4235
KE-39 CTRP2 2.8022 6.5385 2.3598 23.1583
IM95 CTRP2 2.8114 7.0345 2.2036 23.6947
MKN74 CTRP2 3.0027 6.1266 2.7021 21.3164
AGS CTRP2 3.0937 6.1701 2.789 20.7261
OCUM-1 CTRP2 3.2725 8.8665 1.9619 23.2502
ECC12 CTRP2 3.2931 4.4544 3.2874 18.3485
MKN1 CTRP2 3.3314 7.3806 2.6354 20.5947
HuG1-N CTRP2 3.5871 7.0169 3.0459 18.3258
Fu97 CTRP2 3.7295 8.4812 2.6002 19.6288
MKN7 CTRP2 3.8815 8.4238 2.7815 18.5278
SNU-620 CTRP2 4.1643 5.275 4.1404 12.606
SNU-668 CTRP2 4.6425 8.5462 3.4942 13.767
NUGC-4 CTRP2 4.7649 7.8759 3.9247 11.7317
GSU CTRP2 4.9601 6.131 4.8363 7.6599
SNU-719 CTRP2 5.5974 10.6389 3.3647 12.1304
LMSU CTRP2 5.6402 8.8697 4.2822 8.2255
SH-10-TC CTRP2 5.6869 9.8293 3.8464 9.9477
Hs 746.T CTRP2 5.8954 13.1201 2.3816 15.4488
MKN45 CTRP2 6.3027 15.8322 1.364 18.3381
SNG-M CTRP2 3.1711 7.9729 2.2316 22.5493
SNU-685 CTRP2 3.811 7.2178 3.2098 17.0722
SNU-1077 CTRP2 7.9498 9.5506 5.5132 0.3426
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C CTRP2 1.1422 3.1733 1.133 32.6896
SW579 CTRP2 2.6593 6.4271 2.239 24.0246
FTC-238 CTRP2 2.7635 4.6414 2.7275 21.9787
CAL-62 CTRP2 2.8351 5.6836 2.6336 22.0771
CGTH-W-1 CTRP2 3.3731 6.4493 3.0093 19.0857
BHT-101 CTRP2 4.0563 7.7279 3.262 16.1978
TT2609-C02 CTRP2 4.2794 7.8962 3.4211 14.9827
B-CPAP CTRP2 4.3558 8.6442 3.1636 15.8042
FTC-133 CTRP2 5.0363 8.5371 3.883 11.2365
8305C CTRP2 5.1012 14.1303 1.1908 21.4194
ML-1 [Human leukemia] CTRP2 6.5487 11.8662 3.5423 9.5567
TT CTRP2 7.578 15.6695 2.4424 12.1522
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 18 CTRP2 1.2745 5.4774 0.982 32.7289
YD-10B CTRP2 1.6199 3.5024 1.6101 29.5093
CAL-33 CTRP2 1.8315 5.8284 1.5039 29.1751
HSC-4 CTRP2 1.8537 5.8797 1.5148 29.0667
Detroit 562 CTRP2 1.9991 4.4882 1.9371 27.159
PE/CA-PJ41 (clone D2) CTRP2 2.0683 3.4697 2.0658 26.4976
PE/CA-PJ15 CTRP2 2.125 5.1214 1.979 26.6082
BICR 22 CTRP2 2.1946 3.6757 2.1902 25.6625
FaDu CTRP2 2.1951 3.0167 2.1951 25.6447
PE/CA-PJ34 (clone C12) CTRP2 2.3434 4.6301 2.2856 24.8517
CAL-27 CTRP2 2.5417 4.3298 2.52 23.408
HSC-2 CTRP2 2.5494 4.5619 2.5099 23.4171
HSC-3 CTRP2 2.555 4.7563 2.4953 23.4485
BICR 6 CTRP2 2.5831 5.7115 2.3524 23.8565
PE/CA-PJ49 CTRP2 2.653 4.4162 2.6299 22.6715
SNU-1076 CTRP2 2.9419 6.1055 2.6417 21.7188
BHY CTRP2 2.9952 7.4715 2.2415 23.0174
SCC-25 CTRP2 3.1701 6.6839 2.7122 20.7776
BICR 56 CTRP2 3.3895 5.3115 3.3092 17.9609
SCC-4 CTRP2 3.5267 6.4579 3.1737 18.0258
SNU-1214 CTRP2 4.1068 8.7178 2.8798 17.5575
BICR 31 CTRP2 4.5828 8.95 3.2466 14.9081
YD-8 CTRP2 4.6136 10.6359 2.4693 17.9096
SNU-899 CTRP2 5.0048 10.9485 2.68 16.1825
SCC-9 CTRP2 5.0648 10.9066 2.7554 15.7493
SNU-1041 CTRP2 5.1569 8.4944 4.0191 10.3954
SNU-46 CTRP2 5.6162 9.9198 3.7392 10.5416
SNU-1066 CTRP2 6.9816 11.0377 4.2792 5.7924
BICR 16 CTRP2 8.9495 15.7147 3.3626 6.6831
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1376 CTRP2 1.4837 6.5851 0.9097 32.2432
253J CTRP2 1.7915 3.4872 1.7853 28.3542
U-BLC1 CTRP2 1.8827 6.4996 1.3707 29.4551
647V CTRP2 2.0889 3.0945 2.0887 26.3529
KU-19-19 CTRP2 2.1568 9.8406 0.3886 31.5776
5637 CTRP2 2.2441 4.8771 2.1476 25.6452
J82 CTRP2 2.2583 6.721 1.7097 27.1202
JMSU-1 CTRP2 2.3036 7.8978 1.3398 28.2327
KMBC-2 CTRP2 2.8006 4.9558 2.7313 21.8454
CAL-29 CTRP2 2.9711 5.6369 2.7922 21.0921
639V CTRP2 3.0309 5.6007 2.8653 20.6472
SCaBER CTRP2 3.1827 6.1852 2.8818 20.1212
UM-UC-3 CTRP2 3.4593 8.2444 2.4219 21.0375
SW1710 CTRP2 3.7286 7.0604 3.1817 17.4112
TCCSUP CTRP2 3.8078 7.5646 3.0688 17.6194
RT-112 CTRP2 4.317 6.5717 3.9928 12.6728
BFTC-905 CTRP2 4.3258 8.0427 3.4043 14.9279
VM-CUB-1 CTRP2 4.3301 8.3628 3.2657 15.465
HT-1197 CTRP2 4.3632 8.1266 3.4052 14.8273
UM-UC-1 CTRP2 4.4314 9.5985 2.7928 17.0837
T24 CTRP2 4.5338 7.8447 3.7045 13.2005
RT-4 CTRP2 4.7822 5.8386 4.7171 8.6332
BC-3C CTRP2 4.9994 9.4554 3.4054 13.2755
253J-BV CTRP2 5.0538 8.9281 3.712 11.8955
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.2485 12.2981 3.8554 7.1078

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG
DIG Name DIG ID PubChem CID Functional Classification
Benzyl alcohol E00010 244 Antimicrobial preservative; Solvent
Cetyl alcohol E00061 2682 Coating agent; Emollient; Emulsifying agent; Stiffening agent
Docusate sodium E00563 23673837 Surfactant
Ethyl acetate E00192 8857 Flavoring agent; Solvent
Isopropyl alcohol E00070 3776 Antimicrobial preservative; Solvent
Lactic acid E00020 612 Acidulant
Sodium chloride E00077 5234 Diluent; Tonicity agent
Sodium hydroxide E00234 14798 Alkalizing agent
Sodium laureth-3 sulfate E00564 23674622 Surfactant
Stearyl alcohol E00172 8221 Emollient; Emulsifying agent; Stiffening agent; Viscosity-controlling agent
Water E00035 962 Solvent
Laureth-2 E00376 76457 Dispersing agent; Emulsifying agent; Gelling agent; Penetration agent; Solubilizing agent; Surfactant; Viscosity-controlling agent
Myristyl alcohol E00171 8209 Emollient; Emulsion stabilizing agent; Oleaginous vehicle; Surfactant; Viscosity-controlling agent
Octyldodecanol E00269 21414 Emollient; Emulsifying agent; Lubricant; Solvent; Viscosity-controlling agent
Sorbitan monostearate E00524 16218600 Dispersing agent; Emulsifying agent; Solubilizing agent; Surfactant; Suspending agent; Vaccine adjuvant
Disodium laureth sulfosuccinate E00713 10173122 Surfactant
⏷ Show the Full List of 16 Pharmaceutical Excipients of This Drug
Pharmaceutical Formulation
Formulation Name Drug Dosage Dosage Form Route
Ciclopirox 0.77% cream 0.77% Cream Topical
Ciclopirox 0.77% suspension 0.77% Suspension Topical
Ciclopirox 0.77% gel 0.77% Gel Topical
Ciclopirox 8% solution 8% Solution Topical
Ciclopirox 1% shampoo 1% Shampoo Topical
Jump to Detail Pharmaceutical Formulation Page of This Drug

References

1 Ciclopirox FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076435.
3 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
4 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
5 Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood. 2009 Oct 1;114(14):3064-73. doi: 10.1182/blood-2009-03-209965. Epub 2009 Jul 9.
6 Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation. Arch Toxicol. 2022 Jul;96(7):1975-1987. doi: 10.1007/s00204-022-03291-5. Epub 2022 Apr 18.
7 Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4929-34. doi: 10.1073/pnas.0812308106. Epub 2009 Mar 2.
8 Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells. Neurotox Res. 2009 May;15(4):367-80. doi: 10.1007/s12640-009-9043-z. Epub 2009 Mar 20.
9 Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood. 2005 Jun 15;105(12):4613-9. doi: 10.1182/blood-2004-10-3980. Epub 2005 Mar 1.
10 Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. Mol Neurodegener. 2006 Jul 26;1:6. doi: 10.1186/1750-1326-1-6.