Details of the Drug

General Information of Drug (ID: DMV7IM6)

Drug Name
Histamine Phosphate
Synonyms
Histamine acid phosphate; Histamine biphosphate; Histamine dihydrogen phosphate; Histamine diphosphate; Histamine phosphate [USP]; Histamine positive; H0147; Histamine phosphate (TN); Histamine phosphate (USP); Histamine phosphate (1:2); 1H-Imidazole-4-ethanamine, phosphate (1:2); 2-Imidazol-4-ylethylamine orthophosphoric acid (1:2); 4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate); 4-(2-Aminoethyl)imidazole di-acid phosphate; 4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
Indication
Disease Entry ICD 11 Status REF
Diagnostic imaging N.A. Approved [1]
Osteoarthritis FA00-FA05 Approved [2]
Therapeutic Class
Diagnostic Agents
ATC Code
V04CG03: Histamine Phosphate
V04CG: Tests for gastric secretion
V04C: OTHER DIAGNOSTIC AGENTS
V04: DIAGNOSTIC AGENTS
V: VARIOUS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
1		 Molecular Weight 307.14
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 2
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 10
Chemical Identifiers
Formula
C5H15N3O8P2
IUPAC Name
2-(1H-imidazol-5-yl)ethanamine;phosphoric acid
Canonical SMILES
C1=C(NC=N1)CCN.OP(=O)(O)O.OP(=O)(O)O
InChI
InChI=1S/C5H9N3.2H3O4P/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4)
InChIKey
ZHIBQGJKHVBLJJ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
65513
ChEBI ID
CHEMBL51193
CAS Number
51-74-1
TTD ID
D0EN0G
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histamine receptor (HR) TT7CXIM NOUNIPROTAC Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 000734.
2 Histamine Phosphate FDA Label
3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.