Details of the Drug

General Information of Drug (ID: DMVUW8A)

Drug Name
AVI-6002
Synonyms
NeuGene Plus (Ebola virus), AVI; Neugene (Ebola virus), AVI BioPharma; Polymerase cofactor VP35 modulator (Ebola virus infection,TSO), AVI BioPharma; Viral membrane associated protein VP24 modulator (Ebola virus infection, TSO), AVI BioPharma; AVI-4537 + AVI-4538 + AVI-4539 (Ebola virus infection), AVI BioPharma
Indication
Disease Entry ICD 11 Status REF
Ebola virus infection 1D60.0 Phase 1 [1]
Cross-matching ID
TTD ID
D04LIH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ebola virus VP24 messenger RNA (EV VP24 mRNA) TTDJLWQ VP24_EBOSU Modulator [2]
Ebola virus VP35 messenger RNA (EV VP35 mRNA) TT3Z102 VP35_EBOSU Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01353027) Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus. U.S. National Institutes of Health.
2 Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections. Viruses. 2012 November; 4(11): 2806-2830.