Details of the Drug

General Information of Drug (ID: DMVUW8A)

Drug Name

AVI-6002

Synonyms

NeuGene Plus (Ebola virus), AVI; Neugene (Ebola virus), AVI BioPharma; Polymerase cofactor VP35 modulator (Ebola virus infection,TSO), AVI BioPharma; Viral membrane associated protein VP24 modulator (Ebola virus infection, TSO), AVI BioPharma; AVI-4537 + AVI-4538 + AVI-4539 (Ebola virus infection), AVI BioPharma

Indication

Disease Entry	ICD 11	Status	REF
Ebola virus infection	1D60.0	Phase 1	[1]
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Cross-matching ID

TTD ID: D04LIH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ebola virus VP24 messenger RNA (EV VP24 mRNA)	TTDJLWQ	VP24_EBOSU	Modulator	[2]
Ebola virus VP35 messenger RNA (EV VP35 mRNA)	TT3Z102	VP35_EBOSU	Modulator	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01353027) Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus. U.S. National Institutes of Health.
2	Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections. Viruses. 2012 November; 4(11): 2806-2830.