Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT3PQ2Y)

• DTT Name: Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) DTT Info
• Gene Name: Malaria DHOdehase

Molecule-Related Drug & Molecule List

4 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Artemisinin	DMOY7W3	Malaria	1F40-1F45	Approved	[1]
Atovaquone	DMY4UMW	Fungal infection	1F29-1F2F	Approved	[2]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[3]
Teriflunomide	DMQ2FKJ	Hyperlipidaemia	5C80	Approved	[4]

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Avastin+/-Tarceva	DMA86FL	Non-small-cell lung cancer	2C25.Y	Phase 3	[5]

41 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
1,4-Naphthoquinone	DMTCMH7	Discovery agent	N.A.	Investigative	[5]
1-hydroxy-2-dodecyl-4(1H)quinolone	DMGBSWP	Discovery agent	N.A.	Investigative	[6]
2-(2-bromo-2-naphthamido)benzoic acid	DMFK0GM	Discovery agent	N.A.	Investigative	[7]
2-(2-naphthamido)benzoic acid	DMN176Y	Discovery agent	N.A.	Investigative	[7]
2-(3-(3,5-dichlorophenyl)ureido)benzoic acid	DMM9WB0	Discovery agent	N.A.	Investigative	[8]
2-[(biphenyl-4-carbonyl)-amino]-benzoic acid	DMDT7SK	Discovery agent	N.A.	Investigative	[7]
3,6,9,12,15-PENTAOXATRICOSAN-1-OL	DMMVL5P	Discovery agent	N.A.	Investigative	[9]
3-hydroxy-2-phenylquinoline-4-carboxylic acid	DMIVDFW	Discovery agent	N.A.	Investigative	[10]
5,8-hydroxy-naphthoquinone	DM1SO62	Discovery agent	N.A.	Investigative	[5]
5-Fluoro orotate	DMLSC10	Discovery agent	N.A.	Investigative	[11]
8-aminoquinolines	DMN8QAF	Discovery agent	N.A.	Investigative	[12]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[13]
Antimycin A	DM2EMCW	Discovery agent	N.A.	Investigative	[14]
Antiproliferative Agent A771726	DM9THZE	Discovery agent	N.A.	Investigative	[13]
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[13]
Cinchoninic acid	DMOJ917	Discovery agent	N.A.	Investigative	[5]
Cyanide	DMJE4HK	Discovery agent	N.A.	Investigative	[14]
Decylamine-N,N-Dimethyl-N-Oxide	DM2WEB9	Discovery agent	N.A.	Investigative	[13]
Dichloroally-lawsone	DMAU5VM	Discovery agent	N.A.	Investigative	[5]
Dichloroallyl lawsone	DMXGV63	Discovery agent	N.A.	Investigative	[15]
Diethyl 2-((biphenyl-3-ylamino)methylene)malonate	DM7YHBR	Discovery agent	N.A.	Investigative	[16]
Dihydroorotate	DM76BGZ	Discovery agent	N.A.	Investigative	[17]
DSM1	DM1LK0C	Malaria	1F40-1F45	Investigative	[18]
DSM2	DMZYQOB	Malaria	1F40-1F45	Investigative	[18]
Ethyl 3-(biphenyl-3-ylamino)-2-cyanoacrylate	DM5XYFN	Discovery agent	N.A.	Investigative	[16]
GNF-PF-85	DMB6FN7	Discovery agent	N.A.	Investigative	[19]
Isoxazol	DMXAD8E	Discovery agent	N.A.	Investigative	[5]
Lauryl Dimethylamine-N-Oxide	DM3W2OE	Discovery agent	N.A.	Investigative	[13]
LY214352	DMKZJVA	Discovery agent	N.A.	Investigative	[20]
N-(3,5-dichlorophenyl)-2-methyl-3-nitrobenzamide	DM9B1ID	Discovery agent	N.A.	Investigative	[16]
N-(4-bromo-2-methylphenyl)-2-naphthamide	DMSNZV1	Discovery agent	N.A.	Investigative	[16]
N-(Biphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide	DMSO7FW	Discovery agent	N.A.	Investigative	[21]
NSC 665564	DMX4DT7	Discovery agent	N.A.	Investigative	[22]
Orotate	DMMB29S	Discovery agent	N.A.	Investigative	[11]
Orotic acid	DMP6BSH	Discovery agent	N.A.	Investigative	[17]
Plumbagin	DM9BS50	Discovery agent	N.A.	Investigative	[5]
Polyporic acid	DMN6Q4E	Discovery agent	N.A.	Investigative	[5]
Redoxal	DM2S496	Discovery agent	N.A.	Investigative	[15]
Salicylhydroxamic acid	DMGLSPC	Discovery agent	N.A.	Investigative	[14]
Triazine	DM8LYSB	Discovery agent	N.A.	Investigative	[5]
Undecylamine-n,n-dimethyl-n-oxide	DM4AYC2	Discovery agent	N.A.	Investigative	[9]

References

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