Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTA0OSE)

• DTT Name: Lactase-phlorizin hydrolase (LCT) DTT Info
• Gene Name: LCT

Molecule-Related Drug & Molecule List

10 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2,5-dideoxy-2,5-imino-D-altritol	DMI1O54	Discovery agent	N.A.	Investigative	[1]
2,5-dideoxy-2,5-imino-dl-glycero-D-manno-heptitol	DMKP7O0	Discovery agent	N.A.	Investigative	[2]
2-Deoxy-2fluoro-Glucose	DMMC8IG	Discovery agent	N.A.	Investigative	[3]
Alpha-D-Mannose	DMF5DLW	Discovery agent	N.A.	Investigative	[3]
D-Gluconhydroximo-1,5-Lactam	DM527XP	Discovery agent	N.A.	Investigative	[4]
ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE	DM0O4A2	Discovery agent	N.A.	Investigative	[4]
Fucose	DMAHMSV	N. A.	N. A.	Investigative	[3]
Gluconolactone	DMO071E	Discovery agent	N.A.	Investigative	[4]
Hyacinthacine B3	DMJ9KNU	Discovery agent	N.A.	Investigative	[5]
Nojirimycine Tetrazole	DMYZRTB	Discovery agent	N.A.	Investigative	[4]

References

• [1] 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem. 2010 Jun 1;18(11):3790-4.
• [2] Nitrogen-containing furanose and pyranose analogues from Hyacinthus orientalis. J Nat Prod. 1998 May;61(5):625-8.
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
• [4] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
• [5] New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica. J Nat Prod. 2002 Dec;65(12):1875-81.