Details of the Drug

General Information of Drug (ID: DMF5DLW)

Drug Name
Alpha-D-Mannose
Synonyms
alpha-D-Mannose; alpha-D-Mannopyranose; alpha-Mannose; alpha-D-Man; UNII-W3F28J9G0W; CHEBI:28729; 7296-15-3; W3F28J9G0W; 3h-mannose; Manalpha1,; 1rdl; 1rin; 29696-75-1; Epitope ID:130701; AC1Q59RC; AC1L4HD7; SCHEMBL76882; CHEMBL365590; WQZGKKKJIJFFOK-PQMKYFCFSA-N; ZINC3860903; FT-0773891; C00936; WURCS=2.0/1,1,0/[a1122h-1a_1-5]/1/
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 180.16
Logarithm of the Partition Coefficient (xlogp) -2.6
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 5
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C6H12O6
IUPAC Name
(2S,3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Canonical SMILES
C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
InChI
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKey
WQZGKKKJIJFFOK-PQMKYFCFSA-N
Cross-matching ID
PubChem CID
185698
ChEBI ID
CHEMBL365590
CAS Number
7296-15-3
TTD ID
D07LUR
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ADAM metallopeptidase 33 (ADAM33) TTQICM2 ADA33_HUMAN Inhibitor [1]
Alpha-galactosidase A (GLA) TTIS03D AGAL_HUMAN Inhibitor [1]
Antithrombin-III (ATIII) TT4QPUL ANT3_HUMAN Inhibitor [1]
Beta-2-glycoprotein 1 (APOH) TT2OUI9 APOH_HUMAN Inhibitor [1]
Cathepsin D (CTSD) TTPT2QI CATD_HUMAN Inhibitor [1]
Cholinesterase (BCHE) TTEB0GD CHLE_HUMAN Inhibitor [1]
Cytotoxic T-lymphocyte protein 4 (CTLA-4) TTI2S1D CTLA4_HUMAN Inhibitor [1]
Deoxyribonuclease I (DNASE1) TTYWGOJ DNAS1_HUMAN Inhibitor [1]
Dipeptidyl peptidase 4 (DPP-4) TTDIGC1 DPP4_HUMAN Inhibitor [1]
Glycoprotein hormones alpha (CGA) TTFC29G GLHA_HUMAN Inhibitor [1]
Heparin cofactor II (SERPIND1) TT8XSKJ HEP2_HUMAN Inhibitor [1]
Immunoglobulin epsilon Fc receptor gamma (FCERG) TTDGEC0 FCERG_HUMAN Inhibitor [1]
Influenza Hemagglutinin (Influ HA) TTF4CAM HEMA_I34A1 Inhibitor [1]
Influenza Neuraminidase (Influ NA) TT50QJ3 NRAM_I33A0 Inhibitor [1]
Insulin-like growth factor I receptor (IGF1R) TTHRID2 IGF1R_HUMAN Inhibitor [1]
Interleukin 6 receptor (IL6R) TT0E5SK IL6RA_HUMAN ; IL6RB_HUMAN Inhibitor [1]
Lactase-phlorizin hydrolase (LCT) TTA0OSE LPH_HUMAN Inhibitor [1]
Lactotransferrin (LTF) TTSZDQU TRFL_HUMAN Inhibitor [1]
Liver carboxylesterase (CES1) TTMF541 EST1_HUMAN Inhibitor [1]
Low-density lipoprotein receptor (LDL-R) TTH0DUS LDLR_HUMAN Inhibitor [1]
Membrane-associated lectin type-C (CD209) TTBXIM9 CD209_HUMAN Inhibitor [1]
Nitric-oxide synthase brain (NOS1) TTZUFI5 NOS1_HUMAN Inhibitor [1]
Phospholipase A2 (PLA2G1B) TT9V5JH PA21B_HUMAN Inhibitor [1]
Prostaglandin G/H synthase 1 (COX-1) TT8NGED PGH1_HUMAN Inhibitor [1]
Reticulon-4 receptor (RTN4R) TTVRZUO RTN4R_HUMAN Inhibitor [1]
Rhodopsin (RHO) TTH0KSX OPSD_HUMAN Inhibitor [1]
T-cell surface antigen CD2 (CD2) TTJDUNO CD2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.