Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZCRP3)

DTT Name ERK activator kinase (MEK) DTT Info
Gene Name MEK

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
1 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
ARRY-162 DM1P6FR Melanoma 2C30 Approved [1]
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5 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
NFX-179 DM77XQT Neurofibromatosis 1 LD2D.10 Phase 2 [2]
HL-085 DMJDVCW Melanoma 2C30 Phase 1/2 [3]
BI 3011441 DMFJGUL Solid tumour/cancer 2A00-2F9Z Phase 1 [4]
GDC-0623 DMDY08K Solid tumour/cancer 2A00-2F9Z Phase 1 [5]
RG7304 DMGFAVQ Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
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13 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Azetidine derivative 2 DMTB3KS N. A. N. A. Patented [7]
Benzoheterocyclic compound 1 DM3K25J N. A. N. A. Patented [7]
Benzoimidazole derivative 1 DMUJFCK N. A. N. A. Patented [7]
Benzoimidazole derivative 2 DMHX5VO N. A. N. A. Patented [7]
N-(arylamino)sulfonamide derivative 1 DM8GJA7 N. A. N. A. Patented [7]
P-toluenesulfonate derivative 1 DME57SJ N. A. N. A. Patented [7]
PMID28594589-Compound-TABLE3C1 DMLZV70 N. A. N. A. Patented [7]
PMID28594589-Compound-TABLE3C12 DMPK7IU N. A. N. A. Patented [7]
PMID28594589-Compound-TABLE3C14 DM4KWVF N. A. N. A. Patented [7]
PMID28594589-Compound-TABLE3C2 DMVYG0U N. A. N. A. Patented [7]
Pyridinone compound 1 DM2GR5Q N. A. N. A. Patented [7]
Pyridopyrimidine derivative 1 DMTZK6V N. A. N. A. Patented [7]
Quinazolines and azaquinazoline derivative 1 DME24BI N. A. N. A. Patented [7]
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⏷ Show the Full List of 13 Patented Agent(s)
Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
2 Clinical pipeline report, company report or official report of NFlection Therapeutics
3 Current Development Status of MEK Inhibitors. Molecules. 2017 Sep 26;22(10):1551.
4 Clinical pipeline report, company report or official report of Boehringer Ingelheim.
5 Clinical pipeline report, company report or official report of Genentech (2011).
6 Clinical pipeline report, company report or official report of Roche.
7 MEK inhibitors in oncology: a patent review (2015-Present).Expert Opin Ther Pat. 2017 Aug;27(8):887-906.