Details of Disease

Disease Name

Lymphogranuloma venereum

LGV; lymph granuloma inguinale; climatic or tropical bubo; lymphogranuloma inguinale; strumous bubo; Poradenitis inguinale; Durand-Nicolas-Favre disease

Definition

Infection with the organism Mycobacterium.

Disease Hierarchy

DISJFHYP: Chlamydia trachomatis infectious disease

DISRKXBH: Granuloma inguinale

DIS57XO9: Lymphatic disease

DIS0MMFT: Lymphogranuloma venereum

Disease Identifiers

MONDO ID

MONDO_0005834

MESH ID

D008219

UMLS CUI

C0024286

MedGen ID

44221

SNOMED CT ID

186946009

General Information of Disease (ID: DIS0MMFT)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 7 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Amphotericin B	DMTAJQE	Approved	Small molecular drug	[1]
Demeclocycline	DMZEPFJ	Approved	Small molecular drug	[2]
Doxycycline	DM7ICNU	Approved	Small molecular drug	[3]
Fusidic Acid	DMWVCF3	Approved	Small molecular drug	[4]
Minocycline	DMVN5OH	Approved	Small molecular drug	[5]
Oxytetracycline	DMOVH1M	Approved	Small molecular drug	[6]
Tetracycline	DMZA017	Approved	Small molecular drug	[7]
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⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CWC15	OTFFEP9A	Definitive	Altered Expression	[8]
DHX9	OT5AAOQI	Definitive	Biomarker	[9]
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References

1	Amphotericin B FDA Label
2	Demeclocycline FDA Label
3	Doxycycline FDA Label
4	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
5	Minocycline FDA Label
6	Oxytetracycline FDA Label
7	Tetracycline FDA Label
8	Assessment of the load and transcriptional dynamics of Chlamydia trachomatis plasmid according to strains' tissue tropism.Microbiol Res. 2013 Jul 19;168(6):333-339. doi: 10.1016/j.micres.2013.02.001. Epub 2013 Apr 13.
9	Anal infections with concomitant Chlamydia trachomatis genotypes among men who have sex with men in Amsterdam, the Netherlands.BMC Infect Dis. 2011 Mar 14;11:63. doi: 10.1186/1471-2334-11-63.