Details of Disease

General Information of Disease (ID: DIS3P3TG)

Disease Name Chronic otitis media
Synonyms chronic otitis media (disease); otitis media (disease), chronic
Definition Chronic form of otitis media (disease).
Disease Hierarchy
DISGZDUO: Otitis media
DIS3P3TG: Chronic otitis media
Disease Identifiers
MONDO ID
MONDO_0021204
UMLS CUI
C0271441
MedGen ID
75751
HPO ID
HP:0000389
SNOMED CT ID
21186006

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
FBXO11 TT6G10V moderate Genetic Variation [1]
NR1D1 TTAD1O8 moderate Genetic Variation [2]
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This Disease Is Related to 6 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AQP10 OT8Q5UWS moderate Altered Expression [3]
AQP2 OTQLBKK6 moderate Altered Expression [3]
CLEC4D OTT7X1UC moderate Altered Expression [4]
MUC5B OTPW6K5C moderate Biomarker [5]
SPRR2A OT62ZU6B moderate Altered Expression [6]
TGIF1 OTN9VHAG moderate Genetic Variation [1]
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⏷ Show the Full List of 6 DOT(s)

References

1 A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11.Sci Rep. 2017 Oct 2;7(1):12496. doi: 10.1038/s41598-017-12784-8.
2 Readout-Segmented Echo-Planar DWI for the Detection of Cholesteatomas: Correlation with Surgical Validation.AJNR Am J Neuroradiol. 2019 Jun;40(6):1055-1059. doi: 10.3174/ajnr.A6079. Epub 2019 May 23.
3 Expression of aquaporins mRNAs in patients with otitis media.Acta Otolaryngol. 2018 Aug;138(8):701-707. doi: 10.1080/00016489.2018.1447685. Epub 2018 Apr 1.
4 Expression of C-type lectin receptor mRNA in otitis media with effusion and chronic otitis media with and without cholesteatoma.Auris Nasus Larynx. 2019 Oct;46(5):672-680. doi: 10.1016/j.anl.2018.12.011. Epub 2019 Jan 1.
5 Characterization of mucins in human middle ear and Eustachian tube.Am J Physiol Lung Cell Mol Physiol. 2001 Jun;280(6):L1157-67. doi: 10.1152/ajplung.2001.280.6.L1157.
6 Role of Autophagy in Acquired Cholesteatoma.Otol Neurotol. 2019 Dec;40(10):e993-e998. doi: 10.1097/MAO.0000000000002404.