Details of Disease

General Information of Disease (ID: DISCQV4J)

Disease Name Endophthalmitis
Definition An infectious process affecting the internal structures of the eye.
Disease Hierarchy
DIS184KT: Skin inflammation
DISTTJES: Ocular infection
DISEM33Q: Infectious disease
DISCQV4J: Endophthalmitis
Disease Identifiers
MONDO ID
MONDO_0016047
MESH ID
D009877
UMLS CUI
C0014236
MedGen ID
8633
Orphanet ID
199323
SNOMED CT ID
128295000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
TICAM1 TT2GQT6 Strong Biomarker [1]
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This Disease Is Related to 6 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CUL9 OTPUCLZT Strong Genetic Variation [2]
EFS OT06O7XL Strong Genetic Variation [3]
NTM OTHF0UQU Strong Biomarker [4]
PRF1 OTFVXD7H Strong Biomarker [5]
SLPI OTUNFUU8 Strong Biomarker [6]
TRIM69 OTTEGTRD Strong Biomarker [1]
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⏷ Show the Full List of 6 DOT(s)

References

1 Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria.Infect Immun. 2015 Oct;83(10):3926-36. doi: 10.1128/IAI.00502-15. Epub 2015 Jul 20.
2 Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis.Ophthalmic Res. 2009;42(1):43-8. doi: 10.1159/000219684. Epub 2009 May 28.
3 Corneal transplantation: study of the data of a regional eye bank for the year 2013 and analysis of the evolution of the adverse events reported in France since 2010.Cell Tissue Bank. 2017 Mar;18(1):83-89. doi: 10.1007/s10561-016-9593-2. Epub 2017 Jan 23.
4 Late-onset postoperative Mycobacterium haemophilum endophthalmitis masquerading as inflammatory uveitis: a case report.BMC Infect Dis. 2018 Feb 7;18(1):70. doi: 10.1186/s12879-018-2985-0.
5 A Novel Biomimetic Nanosponge Protects the Retina from the Enterococcus faecalis Cytolysin.mSphere. 2017 Nov 22;2(6):e00335-17. doi: 10.1128/mSphere.00335-17. eCollection 2017 Nov-Dec.
6 Secretory leukocyte protease inhibitor is an inducible antimicrobial peptide expressed in Staphylococcus aureus endophthalmitis.Mediators Inflamm. 2007;2007:93857. doi: 10.1155/2007/93857.