Details of Disease

General Information of Disease (ID: DISFN72S)

Disease Name Rocky mountain spotted fever
Synonyms RMSF; sao Paulo typhus; So Paulo fever; exanthematic typhus of sao Paulo; Fiebre maculosa; Fiebre manchada; Tick typhus; Tobia fever; Brazillian spotted; Choix
Definition
Rocky Mountain spotted fever refers to an infection caused by the bacterium Rickettsia rickettsia. This particular bacterium is carried by certain species of ticks and spread to humans through the bites of infected ticks. Signs and symptoms of the condition generally develop approximately 2 to 14 days following the tick bite and may include fever, rash, headache, muscle pain, chills, and/or confusion. Some affected people may also experience diarrhea, nausea, vomiting, light sensitivity, hallucinations, and/or excessive thirst. Most cases occur in the spring and summer and are found in children. Risk factors for developing the conditioninclude recent hiking or exposure to ticks in an area where the disease is known to occur. Rocky Mountain spotted fever is typically treated with antibiotics (such as doxycycline or tetracycline).
Disease Hierarchy
DIS0S5E8: Spotted fever
DISFN72S: Rocky mountain spotted fever
Disease Identifiers
MONDO ID
MONDO_0019359
MESH ID
D012373
UMLS CUI
C0035793
MedGen ID
48500
Orphanet ID
83311
SNOMED CT ID
186772009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 7 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Amphotericin B DMTAJQE Approved Small molecular drug [1]
Demeclocycline DMZEPFJ Approved Small molecular drug [2]
Doxycycline DM7ICNU Approved Small molecular drug [3]
Fusidic Acid DMWVCF3 Approved Small molecular drug [4]
Minocycline DMVN5OH Approved Small molecular drug [5]
Oxytetracycline DMOVH1M Approved Small molecular drug [6]
Tetracycline DMZA017 Approved Small molecular drug [7]
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⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Amphotericin B FDA Label
2 Demeclocycline FDA Label
3 Doxycycline FDA Label
4 A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
5 Minocycline FDA Label
6 Oxytetracycline FDA Label
7 Tetracycline FDA Label