Details of Disease

Disease Name

Inhalational anthrax

inhalation anthrax; pulmonary anthrax; respiratory anthrax; inhalation anthrax disease; woolsorters' disease; wool-sorters' disease; respiratory anthrax disease

Definition

A rare acute systemic infection caused by the inhalation of Bacillus anthracis spores (e.g. through infected animal products, bioterrorism) and characterized by an initial stage where patients present with non specific symptoms (fever, cough, chills, fatigue) that is followed by an acute phase during which hemorrhagic mediastinitis occurs that can progress into meningitis, gastrointestinal involvement, and refractory shock, that can be fatal, if left untreated.

Disease Hierarchy

DISFPT78: Anthrax

DISII8HD: Inhalational anthrax

Disease Identifiers

MONDO ID

MONDO_0016595

MESH ID

C571912

UMLS CUI

C0155866

MedGen ID

57841

Orphanet ID

247257

SNOMED CT ID

11389007

General Information of Disease (ID: DISII8HD)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Doxycycline	DM7ICNU	Approved	Small molecular drug	[1]
Fusidic Acid	DMWVCF3	Approved	Small molecular drug	[2]
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This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Benzylpenicillin	DMS9503	Phase 3	Small molecular drug	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Doxycycline FDA Label
2	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
3	Human Anthrax: Update of the Diagnosis and Treatment. Diagnostics (Basel). 2023 Mar 10;13(6):1056.