Details of Disease

General Information of Disease (ID: DISL7AGZ)

Disease Name Adenomatous colon polyp
Synonyms adenomatous polyp of colon; colonic adenomatous polyp; colon adenomatous polyp; adenomatous polyp of the colon
Definition
A polypoid adenoma that arises from and protrudes into the lumen of the colon. Epithelial dysplasia is always present. According to the architectural pattern it is classified as tubular, tubulovillous, or villous.
Disease Hierarchy
DISPMZ3U: Colon adenoma
DIS7V594: Colon polyp
DISL7AGZ: Adenomatous colon polyp
Disease Identifiers
MONDO ID
MONDO_0006498
UMLS CUI
C0850572
MedGen ID
163407
SNOMED CT ID
428054006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 2 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aspirin DM672AH Approved Small molecular drug [1]
Salicyclic acid DM2F8XZ Approved Small molecular drug [2]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
PLA2G5 OTQRSKCZ Strong Biomarker [3]
------------------------------------------------------------------------------------

References

1 Aspirin FDA Label
2 A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
3 Three secretory phospholipase A(2) genes that map to human chromosome 1P35-36 are not mutated in individuals with attenuated adenomatous polyposis coli.Cancer Res. 1996 Mar 1;56(5):955-8.