Details of the Drug

General Information of Drug (ID: DM672AH)

Drug Name
Aspirin
Synonyms
ACETYLSALICYLIC ACID; 50-78-2; 2-Acetoxybenzoic acid; o-Acetoxybenzoic acid; O-Acetylsalicylic acid; Polopiryna; Acylpyrin; Ecotrin; Easprin; Acetylsalicylate; Acetophen; Acenterine; Acetosal; Colfarit; Salicylic acid acetate; o-Carboxyphenyl acetate; Enterosarein; Aspergum; Salcetogen; Pharmacin; Acetosalin; Premaspin; Micristin; Benaspir; Aspirdrops; Acetonyl; Aceticyl; Temperal; Acetylin; Empirin; Ecolen; Rhodine; Endydol; Saletin; Rheumintabletten; Solprin acid; Acidum acetylsalicylicum; Globentyl; Pravigard
Indication
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [1]
Adenomatous colon polyp N.A. Approved [1]
Back pain ME84.Z Approved [1]
Common cold CA00 Approved [1]
Headache 8A80-8A84 Approved [1]
Migraine disorder N.A. Approved [1]
Myocardial infarction BA41-BA43 Approved [2]
Osteoarthritis FA00-FA05 Approved [1]
Pain MG30-MG3Z Approved [3]
Cardiovascular disease BA00-BE2Z Phase 3 [3]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2/3 [4]
Colon cancer 2B90.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Analgesics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 180.16
Logarithm of the Partition Coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 1: high solubility and high permeability [5]
Clearance
The drug present in the plasma can be removed from the body at the rate of 12 mL/min/kg [6]
Elimination
1.4% of drug is excreted from urine in the unchanged form [5]
Half-life
The concentration or amount of drug in body reduced by one-half in 0.26 hours [6]
MRTD
The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 370.22296 micromolar/kg/day [7]
Unbound Fraction
The unbound fraction of drug in plasma is 0.68% [6]
Vd
Fluid volume that would be required to contain the amount of drug present in the body at the same concentration as in the plasma 0.22 L/kg [6]
Water Solubility
The ability of drug to dissolve in water is measured as 10 mg/mL [5]
Adverse Drug Reaction (ADR)
ADR Term Variation Related DOT DOT ID REF
Acute lymphocytic leukaemia rs10841753 SLCO1B1 OTNEN8QK [8]
Acute lymphocytic leukaemia rs10740455 C10orf11 OTIPNKTU [8]
Adverse drug reaction rs3892097 CYP2D6 OTZJC802 [9]
Adverse reaction rs7715172 EGFLAM OTACZZJ0 [10]
Adverse reaction rs4502542 FHIT OTGWBSLA [10]
Adverse reaction rs3810046 LAMA1 OTQZMP86 [10]
Anaemia rs1127354 ITPA OTQ47WVR [11]
Capillary leak syndrome Not Available ANGPTL4 OTQL5SPX [12]
Completed suicide rs7569963 CREB1 OT1MDLA1 [13]
Diarrhoea rs2231142 ABCG2 OTW8V2V1 [14]
Gastrointestinal tract mucosal discolouration Not Available VIM OTGZLW4J [12]
Haemorrhagic disorder Not Available MPO OTOOXLIN [12]
Inflammations Not Available PTGES3 OTPPQWI0 [12]
Liver injury rs3129900 C6orf10 OT5GE8IO [15]
Liver injury HLA-DRB5*01:01 HLA-DRB5 OTUX5TWM [15]
Liver injury HLA-DQA1*01:02 HLA-DQA1 OTC6GISG [15]
Liver injury HLA-B*18:01 HLA-B OTNXFWY2 [16]
Suicidal ideation rs4825476 GRIA3 OT34CNBR [17]
Suicidal ideation rs2518224 GRIK2 OTQ41U3D [17]
Urticaria HLA-DQB1*06:09 HLA-DQB OTVVI3UI [18]
Urticaria HLA-DPB1*17:01 HLA-DPB OTW8JHU2 [18]
⏷ Show the Full List of 21 ADR Information of This Drug
Chemical Identifiers
Formula
C9H8O4
IUPAC Name
2-acetyloxybenzoic acid
Canonical SMILES
CC(=O)OC1=CC=CC=C1C(=O)O
InChI
InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
InChIKey
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
2244
ChEBI ID
CHEBI:15365
CAS Number
50-78-2
DrugBank ID
DB00945
TTD ID
D0GY5Z
VARIDT ID
DR00203
INTEDE ID
DR1749
ACDINA ID
D00046
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HMG-CoA reductase (HMGCR) TTPADOQ HMDH_HUMAN Inhibitor [2]
Prostaglandin G/H synthase (COX) TTK0943 PGH1_HUMAN ; PGH2_HUMAN Inhibitor [19]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Probable small intestine urate exporter (SLC17A4) DTHE530 S17A4_HUMAN Substrate [20]
Sodium-dependent phosphate transport protein 1 (SLC17A1) DT8ARWJ NPT1_HUMAN Substrate [21]
Organic anion transporter 2 (SLC22A7) DT0OC1Q S22A7_HUMAN Substrate [22]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [23]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [24]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [25]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [26]
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Substrate [27]
UDP-glucuronosyltransferase 1A6 (UGT1A6) DESD26P UD16_HUMAN Substrate [24]
N-acetyltransferase 2 (NAT2) DER7TA0 ARY2_HUMAN Substrate [24]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein epsilon OT3WQXNA 1433E_HUMAN Gene/Protein Processing [28]
14-3-3 protein theta OTWG7F3H 1433T_HUMAN Gene/Protein Processing [29]
2'-5'-oligoadenylate synthase 1 (OAS1) OT8ZLOCY OAS1_HUMAN Gene/Protein Processing [30]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) OTWICA51 PSD12_HUMAN Gene/Protein Processing [29]
26S proteasome regulatory subunit 10B (PSMC6) OTG8997V PRS10_HUMAN Gene/Protein Processing [31]
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) OT7TNF0L AAPK1_HUMAN Gene/Protein Processing [32]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Gene/Protein Processing [31]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Protein Interaction/Cellular Processes [33]
85/88 kDa calcium-independent phospholipase A2 (PLA2G6) OT5FL0WU PLPL9_HUMAN Gene/Protein Processing [31]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Gene/Protein Processing [34]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute coronary syndrome
ICD Disease Classification BA41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
HMG-CoA reductase (HMGCR) DTT HMGCR 1.01E-05 0.65 1.53
P-glycoprotein 1 (ABCB1) DTP P-GP 3.29E-14 -7.08E-01 -1.99E+00
Probable small intestine urate exporter (SLC17A4) DTP SLC17A4 1.00E-02 -1.74E-01 -8.13E-01
Sodium-dependent phosphate transport protein 1 (SLC17A1) DTP NPT1 3.04E-01 -5.95E-02 -5.29E-01
Organic anion transporter 2 (SLC22A7) DTP OAT2 8.78E-06 -2.19E-01 -6.62E-01
Sulfotransferase 1A1 (SULT1A1) DME SULT1A1 1.61E-12 1.01E+00 1.51E+00
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME UGT1A1 2.00E-01 5.79E-02 3.00E-01
N-acetyltransferase 2 (NAT2) DME NAT2 3.49E-01 -8.28E-02 -3.71E-01
Mephenytoin 4-hydroxylase (CYP2C19) DME CYP2C19 4.03E-02 -1.19E-01 -5.11E-01
Cytochrome P450 2C9 (CYP2C9) DME CYP2C9 2.63E-03 -1.18E-01 -3.80E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Same Disease as Aspirin
DDI Drug Name DDI Drug ID Severity Mechanism Disease REF
Ibuprofen DM8VCBE Major Increased risk of bleeding by the combination of Aspirin and Ibuprofen. Pain [MG30-MG3Z] [35]
Coadministration of a Drug Treating the Disease Different from Aspirin (Comorbidity)
DDI Drug Name DDI Drug ID Severity Mechanism Comorbidity REF
Sodium bicarbonate DMMU6BJ Moderate as urine pH determines the ionization state of weakly acidic or weakly alkaline drugs. Aspirin caused by Sodium bicarbonate mediated altered urine pH. Acidosis [5C73] [36]
Tromethamine DMOBLGK Moderate as urine pH determines the ionization state of weakly acidic or weakly alkaline drugs. Aspirin caused by Tromethamine mediated altered urine pH. Acidosis [5C73] [36]
Glibenclamide DM8JXPZ Moderate Increased risk of hypoglycemia by the combination of Aspirin and Glibenclamide. Acute diabete complication [5A2Y] [37]
Insulin-glulisine DMQI0FU Moderate Increased risk of hypoglycemia by the combination of Aspirin and Insulin-glulisine. Acute diabete complication [5A2Y] [38]
Insulin-aspart DMX7V28 Moderate Increased risk of hypoglycemia by the combination of Aspirin and Insulin-aspart. Acute diabete complication [5A2Y] [38]
Glipizide DMZA5PQ Moderate Increased risk of hypoglycemia by the combination of Aspirin and Glipizide. Acute diabete complication [5A2Y] [37]
Budesonide DMJIBAW Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Budesonide. Asthma [CA23] [39]
Ofloxacin DM0VQN3 Moderate Additive CNS stimulant effects by the combination of Aspirin and Ofloxacin. Bacterial infection [1A00-1C4Z] [40]
Kanamycin DM2DMPO Moderate Increased risk of nephrotoxicity by the combination of Aspirin and Kanamycin. Bacterial infection [1A00-1C4Z] [41]
Sparfloxacin DMB4HCT Moderate Additive CNS stimulant effects by the combination of Aspirin and Sparfloxacin. Bacterial infection [1A00-1C4Z] [40]
Streptomycin DME1LQN Moderate Increased risk of nephrotoxicity by the combination of Aspirin and Streptomycin. Bacterial infection [1A00-1C4Z] [41]
Gemifloxacin DMHT34O Moderate Additive CNS stimulant effects by the combination of Aspirin and Gemifloxacin. Bacterial infection [1A00-1C4Z] [40]
Norfloxacin DMIZ6W2 Moderate Additive CNS stimulant effects by the combination of Aspirin and Norfloxacin. Bacterial infection [1A00-1C4Z] [40]
ABT-492 DMJFD2I Moderate Additive CNS stimulant effects by the combination of Aspirin and ABT-492. Bacterial infection [1A00-1C4Z] [40]
Rabeprazole DMMZXIW Minor Decreased absorption of Aspirin due to altered gastric pH caused by Rabeprazole. Bacterial infection [1A00-1C4Z] [42]
Netilmicin DMRD1QK Moderate Increased risk of nephrotoxicity by the combination of Aspirin and Netilmicin. Bacterial infection [1A00-1C4Z] [41]
Levofloxacin DMS60RB Moderate Additive CNS stimulant effects by the combination of Aspirin and Levofloxacin. Bacterial infection [1A00-1C4Z] [43]
Lomefloxacin DMVRH9C Moderate Additive CNS stimulant effects by the combination of Aspirin and Lomefloxacin. Bacterial infection [1A00-1C4Z] [40]
Etidronic acid DM1XHYJ Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Etidronic acid. Bone paget disease [FB85] [44]
Ketoprofen DMRKXPT Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Ketoprofen. Chronic pain [MG30] [45]
Levomilnacipran DMV26S8 Moderate Increased risk of bleeding by the combination of Aspirin and Levomilnacipran. Chronic pain [MG30] [46]
Anisindione DM2C48U Major Increased risk of bleeding by the combination of Aspirin and Anisindione. Coagulation defect [3B10] [47]
Regorafenib DMHSY1I Major Increased risk of bleeding by the combination of Aspirin and Regorafenib. Colorectal cancer [2B91] [48]
Drospirenone DM1A9W3 Moderate Increased risk of hyperkalemia by the combination of Aspirin and Drospirenone. Contraceptive management [QA21] [49]
Ardeparin DMYRX8B Major Increased risk of bleeding by the combination of Aspirin and Ardeparin. Coronary thrombosis [BA43] [50]
Danaparoid DM6CLBN Major Increased risk of bleeding by the combination of Aspirin and Danaparoid. Deep vein thrombosis [BD71] [50]
Rivaroxaban DMQMBZ1 Major Increased risk of bleeding by the combination of Aspirin and Rivaroxaban. Deep vein thrombosis [BD71] [51]
Sertraline DM0FB1J Moderate Increased risk of bleeding by the combination of Aspirin and Sertraline. Depression [6A70-6A7Z] [46]
Vilazodone DM4LECQ Moderate Increased risk of bleeding by the combination of Aspirin and Vilazodone. Depression [6A70-6A7Z] [46]
Vortioxetine DM6F1PU Moderate Increased risk of bleeding by the combination of Aspirin and Vortioxetine. Depression [6A70-6A7Z] [46]
Milnacipran DMBFE74 Moderate Increased risk of bleeding by the combination of Aspirin and Milnacipran. Depression [6A70-6A7Z] [46]
Escitalopram DMFK9HG Moderate Increased risk of bleeding by the combination of Aspirin and Escitalopram. Depression [6A70-6A7Z] [46]
Desvenlafaxine DMHD4PE Moderate Increased risk of bleeding by the combination of Aspirin and Desvenlafaxine. Depression [6A70-6A7Z] [46]
Clomipramine DMINRKW Moderate Increased risk of bleeding by the combination of Aspirin and Clomipramine. Depression [6A70-6A7Z] [46]
Heme DMGC287 Moderate Increased risk of bleeding by the combination of Aspirin and Heme. Discovery agent [N.A.] [52]
SODIUM CITRATE DMHPD2Y Moderate as urine pH determines the ionization state of weakly acidic or weakly alkaline drugs. Aspirin caused by SODIUM CITRATE mediated altered urine pH. Discovery agent [N.A.] [36]
Apigenin DMI3491 Minor Increased risk of bleeding by the combination of Aspirin and Apigenin. Discovery agent [N.A.] [53]
Fosphenytoin DMOX3LB Minor Increased plasma concentration of Aspirin and Fosphenytoin due to competitive binding of plasma proteins. Epilepsy/seizure [8A61-8A6Z] [54]
Dexlansoprazole DM1DBV5 Minor Decreased absorption of Aspirin due to altered gastric pH caused by Dexlansoprazole. Gastro-oesophageal reflux disease [DA22] [42]
Avapritinib DMK2GZX Major Increased risk of bleeding by the combination of Aspirin and Avapritinib. Gastrointestinal stromal tumour [2B5B] [48]
Brinzolamide DMBAPFG Major Increased risk of metabolic acidosis by the combination of Aspirin and Brinzolamide. Glaucoma [9C61] [55]
Dichlorphenamide DMH7IDQ Major Increased risk of metabolic acidosis by the combination of Aspirin and Dichlorphenamide. Glaucoma [9C61] [55]
Teriflunomide DMQ2FKJ Major Increased risk of hepatotoxicity by the combination of Aspirin and Teriflunomide. Hyper-lipoproteinaemia [5C80] [56]
Sodium acetate anhydrous DMH21E0 Moderate as urine pH determines the ionization state of weakly acidic or weakly alkaline drugs. Aspirin caused by Sodium acetate anhydrous mediated altered urine pH. Hypo-osmolality/hyponatraemia [5C72] [36]
Probenecid DMMFWOJ Moderate Antagonize the effect of Aspirin when combined with Probenecid. Inborn purine/pyrimidine/nucleotide metabolism error [5C55] [48]
Calaspargase pegol DMQZBXI Moderate Increased risk of bleeding by the combination of Aspirin and Calaspargase pegol. Malignant haematopoietic neoplasm [2B33] [57]
Acalabrutinib DM7GCVW Major Increased risk of bleeding by the combination of Aspirin and Acalabrutinib. Mature B-cell lymphoma [2A85] [58]
Ibrutinib DMHZCPO Major Increased risk of bleeding by the combination of Aspirin and Ibrutinib. Mature B-cell lymphoma [2A85] [59]
Ponatinib DMYGJQO Major Increased risk of bleeding by the combination of Aspirin and Ponatinib. Mature B-cell lymphoma [2A85] [58]
Exjade DMHPRWG Major Increased risk of nephrotoxicity by the combination of Aspirin and Exjade. Mineral absorption/transport disorder [5C64] [60]
Deflazacort DMV0RNS Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Deflazacort. Muscular dystrophy [8C70] [39]
Prasugrel DM7MT6E Moderate Increased risk of bleeding by the combination of Aspirin and Prasugrel. Myocardial infarction [BA41-BA43] [61]
Metoclopramide DMFA5MY Minor Altered absorption of Aspirin due to GI dynamics variation caused by Metoclopramide. Nausea/vomiting [MD90] [62]
Nepafenac DMYK490 Moderate Increased risk of bleeding by the combination of Aspirin and Nepafenac. Osteoarthritis [FA00-FA05] [63]
MK-4827 DMLYGH4 Moderate Increased risk of bleeding by the combination of Aspirin and MK-4827. Ovarian cancer [2C73] [48]
Bromfenac DMKB79O Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Bromfenac. Postoperative inflammation [1A00-CA43] [45]
Epoprostenol DMUTYR2 Moderate Increased risk of bleeding by the combination of Aspirin and Epoprostenol. Pulmonary hypertension [BB01] [64]
Iloprost DMVPZBE Moderate Increased risk of bleeding by the combination of Aspirin and Iloprost. Pulmonary hypertension [BB01] [64]
Gatifloxacin DMSL679 Moderate Additive CNS stimulant effects by the combination of Aspirin and Gatifloxacin. Respiratory infection [CA07-CA4Z] [40]
Oxaprozin DM9UB0P Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Oxaprozin. Rheumatoid arthritis [FA20] [45]
Dexamethasone DMMWZET Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Dexamethasone. Rheumatoid arthritis [FA20] [39]
Leflunomide DMR8ONJ Major Increased risk of hepatotoxicity by the combination of Aspirin and Leflunomide. Rheumatoid arthritis [FA20] [56]
Methylprednisolone DM4BDON Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Methylprednisolone. Solid tumour/cancer [2A00-2F9Z] [39]
Curcumin DMQPH29 Minor Increased risk of bleeding by the combination of Aspirin and Curcumin. Solid tumour/cancer [2A00-2F9Z] [65]
Pitolisant DM8RFNJ Moderate Increased risk of GI mucosal injury/bleeding risk by the combination of Aspirin and Pitolisant. Somnolence [MG42] [48]
Caplacizumab DMPUKA7 Major Increased risk of bleeding by the combination of Aspirin and Caplacizumab. Thrombocytopenia [3B64] [62]
Apixaban DM89JLN Major Increased risk of bleeding by the combination of Aspirin and Apixaban. Thrombosis [DB61-GB90] [48]
Cabozantinib DMIYDT4 Major Increased risk of bleeding by the combination of Aspirin and Cabozantinib. Thyroid cancer [2D10] [66]
Tolbutamide DM02AWV Moderate Increased risk of hypoglycemia by the combination of Aspirin and Tolbutamide. Type 2 diabetes mellitus [5A11] [37]
Insulin-detemir DMOA4VW Moderate Increased risk of hypoglycemia by the combination of Aspirin and Insulin-detemir. Type-1/2 diabete [5A10-5A11] [38]
Insulin degludec DMPL395 Moderate Increased risk of hypoglycemia by the combination of Aspirin and Insulin degludec. Type-1/2 diabete [5A10-5A11] [38]
Plazomicin DMKMBES Moderate Increased risk of nephrotoxicity by the combination of Aspirin and Plazomicin. Urinary tract infection [GC08] [41]
Betrixaban DM2C4RF Major Increased risk of bleeding by the combination of Aspirin and Betrixaban. Venous thromboembolism [BD72] [66]
⏷ Show the Full List of 73 DDI Information of This Drug

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG
DIG Name DIG ID PubChem CID Functional Classification
Acrylic acid E00132 6581 Other agent
Allura red AC dye E00338 33258 Colorant
Benzoic acid E00009 243 Antimicrobial preservative
Benzosulfimide E00076 5143 Flavoring agent
Butylated hydroxytoluene E00336 31404 Antioxidant
Calcium carbonate E00198 10112 Binding agent; Buffering agent; Diluent; Opacifying agent
Cholesteryl stearate E00398 118246 Emollient; Emulsifying agent
D&C red no. 27 E00381 83511 Colorant
D&C red no. 30 E00456 3000709 Colorant
Edetic acid E00094 6049 Antimicrobial preservative; Complexing agent
Ethyl acetate E00192 8857 Flavoring agent; Solvent
FD&C blue no. 1 E00263 19700 Colorant
FD&C blue no. 2 E00446 2723854 Colorant
Glyceryl monooleate E00473 5283468 Bioadhesive material; Emollient; Emulsifying agent; Emulsion stabilizing agent; Gelling agent; Modified-release agent; Surfactant
Glyceryl monostearate E00310 24699 Emollient; Emulsifying agent; Emulsion stabilizing agent; Solubilizing agent; Surfactant; Viscosity-controlling agent
Hydrazine yellow E00409 164825 Colorant
Mannitol E00103 6251 Diluent; Flavoring agent; Lyophilization aid; Plasticizing agent; Tonicity agent
methylparaben E00149 7456 Antimicrobial preservative
Propyl 4-hydroxybenzoate E00141 7175 Antimicrobial preservative
Quinoline yellow WS E00309 24671 Colorant
Saccharin sodium anhydrous E00443 656582 Flavoring agent
Saccharin sodium dihydrate E00577 46942257 Flavoring agent
Silotermo carmine G E00611 135487652 Colorant
Sodium lauryl sulfate E00464 3423265 Emulsifying agent; Modified-release agent; Penetration agent; Solubilizing agent; Surfactant; lubricant
Sodium stearyl fumarate E00545 23665634 lubricant
Stearic acid E00079 5281 Emulsifying agent; Solubilizing agent; Viscosity-controlling agent; lubricant
Sucralose E00370 71485 Flavoring agent
Sunset yellow FCF E00255 17730 Colorant
Aluminum trihydroxide E00505 10176082 Alkalizing agent; Vaccine adjuvant
Beta-D-lactose E00099 6134 Diluent; Dry powder inhaler carrier; Lyophilization aid
Brushite E00392 104805 Diluent
Calcium hydrogenphosphate E00294 24441 Diluent
Calcium phosphate E00298 24456 Anticaking agent; Buffering agent; Desiccant; Diluent
Carboxymethylcellulose sodium E00621 Not Available Adsorbent; Binding agent; Disintegrant; Emulsifying agent; Suspending agent; Viscosity-controlling agent
Carmellose sodium E00625 Not Available Disintegrant
Citric acid monohydrate E00271 22230 Acidulant; Antioxidant; Buffering agent; Complexing agent; Flavoring agent
Crospovidone E00626 Not Available Disintegrant
Dextrin E00359 62698 Binding agent; Diluent; Microencapsulating agent; Stiffening agent; Suspending agent; Viscosity-controlling agent
Dextrose anhydrous E00394 107526 Binding agent; Diluent; Flavoring agent; Tonicity agent
Dextrose monohydrate E00538 22814120 Binding agent; Diluent; Flavoring agent; Tonicity agent
Eisenoxyd E00585 56841934 Colorant
Elemental iron E00280 23925 Other agent
FD&C red no. 3 E00629 Not Available Colorant
Ferric hydroxide oxide yellow E00539 23320441 Colorant
Ferrosoferric oxide E00231 14789 Colorant
Hexahydric alcohol E00083 5780 Diluent; Flavoring agent; Humectant; Plasticizing agent
Hypromellose E00634 Not Available Coating agent
Lithol rubin BCA E00607 135423095 Colorant
Magnesium carbonate E00205 11029 Adsorbent; Diluent
Magnesium hydroxide E00374 73981 Adsorbent; Buffering agent
Magnesium oxide E00232 14792 Anticaking agent; Diluent; Emulsifying agent; Glidant; Tonicity agent
Magnesium stearate E00208 11177 lubricant
Polyethylene glycol 1000 E00647 Not Available Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Polyethylene glycol 300 E00651 Not Available Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Polyethylene glycol 400 E00653 Not Available Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Polyethylene glycol 6000 E00655 Not Available Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Polysorbate 20 E00664 Not Available Dispersing agent; Emollient; Emulsifying agent; Plasticizing agent; Solubilizing agent; Surfactant; Suspending agent
Polysorbate 80 E00665 Not Available Dispersing agent; Emollient; Emulsifying agent; Plasticizing agent; Solubilizing agent; Surfactant; Suspending agent
Polyvinyl alcohol E00666 Not Available Coating agent; Emulsion stabilizing agent; Film/Membrane-forming agent
Potassium hydroxide E00233 14797 Alkalizing agent
Povidone E00667 Not Available Binding agent; Coating agent; Disintegrant; Film/membrane-forming agent; Solubilizing agent; Suspending agent
Propylene glycol E00040 1030 Antimicrobial preservative; Humectant; Plasticizing agent; Solvent
Saccharose E00091 5988 Binding agent; Coating agent; Cryoprotectant; Diluent; Flavoring agent; Suspending agent; Viscosity-controlling agent
Silicon dioxide E00670 Not Available Anticaking agent; Opacifying agent; Viscosity-controlling agent
Sodium alginate E00671 Not Available Binding agent; Disintegrant; Suspending agent; Viscosity-controlling agent
Sodium bicarbonate E00424 516892 Alkalizing agent; Diluent
Sodium hydroxide E00234 14798 Alkalizing agent
Sorbitan monolaurate E00508 11046239 Dispersing agent; Emulsifying agent; Solubilizing agent; Surfactant; Suspending agent; Vaccine adjuvant
Talc E00520 16211421 Anticaking agent; Diluent; Glidant; lubricant
Tartaric acid E00029 875 Acidulant; Complexing agent; Flavoring agent
Titanium dioxide E00322 26042 Coating agent; Colorant; Opacifying agent
Triacetin E00080 5541 Humectant; Plasticizing agent; Solvent
Triethyl citrate E00128 6506 Plasticizing agent; Solvent
Vinylpyrrolidone E00668 Not Available Binding agent; Coating agent; Disintegrant; Film/membrane-forming agent; Solubilizing agent; Suspending agent
Water E00035 962 Solvent
Zinc stearate E00209 11178 lubricant
⏷ Show the Full List of 76 Pharmaceutical Excipients of This Drug
Pharmaceutical Formulation
Formulation Name Drug Dosage Dosage Form Route
Aspirin 81 mg tablet 81 mg Oral Tablet Oral
Aspirin 81 mg tablet 81 mg Delayed Release Oral Tablet Oral
Aspirin 325 mg tablet 325 mg Delayed Release Oral Tablet Oral
Aspirin 325 mg tablet 325 mg Enteric Coated Tablet Oral
Aspirin 81 mg tablet 81 mg Enteric Coated Tablet Oral
Aspirin 81 mg tablet 81 mg Delayed Release Tablet Oral
Aspirin 500 mg tablet 500 mg Oral Tablet Oral
Aspirin 300 mg tablet 300 mg Chewable Tablet Oral
Aspirin 60 mg tablet 60 mg Chewable Tablet Oral
Aspirin 81 mg tablet 81 mg Disintegrating Oral Tablet Oral
Aspirin 81 mg tablet 81 mg Chewable Tablet Oral
Aspirin 325 mg tablet 325 mg Oral Tablet Oral
Aspirin 162.5 mg capsule 162.5 mg 24 HR Extended Release Oral Capsule Oral
Aspirin 120 mg tablet 120 mg Chewable Tablet Oral
Jump to Detail Pharmaceutical Formulation Page of This Drug

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