Details of Disease

General Information of Disease (ID: DISOTCOX)

Disease Name Enuresis
Synonyms enuresis
Disease Class 6C00: Enuresis
Definition
An elimination disorder characterized by urinary incontinence, whether involuntary or intentional, which is not due to a medical condition and which occurs at or beyond an age at which continence is expected (usually 5 years).
Disease Hierarchy
DISKFW6V: Psychiatric disorder
DISOTCOX: Enuresis
ICD Code
ICD-11
ICD-11: 6C00
ICD-10
ICD-10: F98.0
Disease Identifiers
MONDO ID
MONDO_0024290
MESH ID
D004775
UMLS CUI
C0014394
MedGen ID
8649
HPO ID
HP:0000805

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Vasopressin DMQ2FPC Approved Small molecular drug [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
AVPR2 TTK8R02 Strong Genetic Variation [2]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AMY1A OT6G4B8O Strong Altered Expression [3]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2168).
2 Relief of nocturnal enuresis by desmopressin is kidney and vasopressin type 2 receptor independent.J Am Soc Nephrol. 2007 May;18(5):1534-9. doi: 10.1681/ASN.2006080907. Epub 2007 Mar 27.
3 Adenotonsillectomy can decrease enuresis and sympathetic nervous activity in children with obstructive sleep apnea syndrome.J Pediatr Urol. 2017 Feb;13(1):41.e1-41.e8. doi: 10.1016/j.jpurol.2016.10.009. Epub 2016 Nov 9.