Details of Disease | DrugMAP

General Information of Disease (ID: DISOYCQC)

Disease Name	Keratoconjunctivitis
Definition	Inflammation of both the cornea and the conjunctiva.
Disease Hierarchy	DISH7H5I: Human disease DISMFOEI: Keratitis DISGOZ4P: Conjunctivitis DISOYCQC: Keratoconjunctivitis
Disease Identifiers	MONDO ID MONDO_0004768 MESH ID D007637 UMLS CUI C0022573 MedGen ID 44014 HPO ID HP:0001096 SNOMED CT ID 88151007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 4 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MS4A2	OTMCAS2D	Strong	Genetic Variation	[1]
PAK3	OT80M3BV	Strong	Biomarker	[2]
PHF11	OT5F6LUP	Strong	Genetic Variation	[1]
PLD3	OTL07SP2	Strong	Biomarker	[3]
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References

1	Alteration in apyrase enzyme attenuated virulence of Shigella flexneri.Microb Pathog. 2016 Feb;91:123-8. doi: 10.1016/j.micpath.2015.12.004. Epub 2015 Dec 17.
2	N-acetylcysteine supplementation reduces oxidative stress for cytosine arabinoside in rat model.Int Ophthalmol. 2017 Feb;37(1):209-214. doi: 10.1007/s10792-016-0259-7. Epub 2016 May 23.
3	Hemorrhagic viral keratoconjunctivitis in Taiwan caused by adenovirus types 19 and 37: applicability of polymerase chain reaction-restriction fragment length polymorphism in detecting adenovirus genotypes.Cornea. 2001 Apr;20(3):295-300. doi: 10.1097/00003226-200104000-00011.