General Information of Disease (ID: DISS46MZ)

Disease Name Obsolete diabetes mellitus, noninsulin-dependent
Definition Duplicate terms.
Disease Hierarchy
DIS01GPL: Grass pollen hypersensitivity
DISS46MZ: Obsolete diabetes mellitus, noninsulin-dependent

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 5 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
MAPK8IP1 TTXKZ8Q Limited Autosomal dominant [1]
AKT2 TTH24WI Strong Autosomal dominant [2]
GCK TTDLNGZ Strong Autosomal dominant [2]
HNF1A TT01M3K Strong Autosomal dominant [2]
HNF4A TT2F3CD Strong Autosomal dominant [2]
------------------------------------------------------------------------------------
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCC8 DTI58LU Strong Autosomal dominant [2]
KCNJ11 DTGZICY Strong Autosomal dominant [2]
------------------------------------------------------------------------------------
This Disease Is Related to 12 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
GPD2 OTV232Y7 No Known Autosomal dominant [3]
IGF2BP2 OT4ZSEEE No Known Unknown [2]
MAPK8IP1 OTDAWAUZ Limited Autosomal dominant [1]
PPP1R3A OTJL9VYP Limited Unknown [1]
RETN OTW5Z1NH Limited Autosomal dominant [1]
ABCC8 OTCWQ54I Strong Autosomal dominant [2]
AKT2 OTBB632K Strong Autosomal dominant [2]
GCK OTR3Q0NN Strong Autosomal dominant [2]
HNF1A OT9DOUKL Strong Autosomal dominant [2]
HNF1B OTSYIC3T Strong Autosomal dominant [2]
HNF4A OTY1TOAB Strong Autosomal dominant [2]
KCNJ11 OTPUUELV Strong Autosomal dominant [2]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 DOT(s)

References

1 Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
2 The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. Genet Med. 2022 Aug;24(8):1732-1742. doi: 10.1016/j.gim.2022.04.017. Epub 2022 May 4.
3 Mutation in the calcium-binding domain of the mitochondrial glycerophosphate dehydrogenase gene in a family of diabetic subjects. Biochem Biophys Res Commun. 1997 Feb 24;231(3):570-2. doi: 10.1006/bbrc.1997.6147.