Details of Disease

General Information of Disease (ID: DISS7ANY)

Disease Name Tendinitis
Synonyms tendon inflammation; tendonitis; inflammation of tendon
Definition
Inflammation of a tendon, usually resulting from an overuse injury. It is characterized by swelling of the tendon, tenderness around the inflamed tendon, and pain while moving the affected area of the body.
Disease Hierarchy
DISCIXF0: Myositis disease
DISJH7UX: Tendinopathy
DISWD40R: Disease
DISS7ANY: Tendinitis
Disease Identifiers
MONDO ID
MONDO_0004857
MESH ID
D052256
UMLS CUI
C0039503
MedGen ID
21094
HPO ID
HP:0025230
SNOMED CT ID
34840004

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 4 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CCN2 TTIL516 Strong Biomarker [1]
LRP5 TT7VMG4 Strong Biomarker [2]
MMP1 TTMX39J Strong Biomarker [3]
POSTN TT8ALTZ Strong Biomarker [1]
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This Disease Is Related to 2 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
FMOD OT9EJ5H8 Strong Biomarker [4]
PRB1 OTV0SYMD Strong Biomarker [5]
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References

1 Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury.J Orthop Res. 2010 Mar;28(3):298-307. doi: 10.1002/jor.20984.
2 Expression of Wnt pathway mediators in metaplasic tissue in animal model and clinical samples of tendinopathy.Rheumatology (Oxford). 2013 Sep;52(9):1609-18. doi: 10.1093/rheumatology/ket214. Epub 2013 Jun 17.
3 Low-level laser therapy in experimental model of collagenase-induced tendinitis in rats: effects in acute and chronic inflammatory phases.Lasers Med Sci. 2013 May;28(3):989-95. doi: 10.1007/s10103-012-1189-x. Epub 2012 Aug 28.
4 Sustained expression of proteoglycans and collagen type III/type I ratio in a calcified tendinopathy model.Rheumatology (Oxford). 2010 Feb;49(2):231-9. doi: 10.1093/rheumatology/kep384. Epub 2009 Dec 2.
5 Long-term local PDGF delivery using porous microspheres modified with heparin for tendon healing of rotator cuff tendinitis in a rabbit model.Carbohydr Polym. 2019 Apr 1;209:372-381. doi: 10.1016/j.carbpol.2019.01.017. Epub 2019 Jan 7.