Details of Disease | DrugMAP

General Information of Disease (ID: DISXXS3L)

Disease Name	Colonic disorder
Synonyms	disorder of colon; disease or disorder of colon; disease of colon; colon disorder; colon disease or disorder; colon disease
Definition	Pathological processes in the colon region of the large intestine (intestine, large).
Disease Hierarchy	DISWD40R: Disease DISKU8JE: Large intestine disorder DISXXS3L: Colonic disorder
Disease Identifiers	MONDO ID MONDO_0003409 MESH ID D003108 UMLS CUI C0009373 MedGen ID 1049 SNOMED CT ID 128524007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 5 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CRTC3	OTVIGVUW	Strong	Genetic Variation	[1]
KIF3B	OT0HJREB	Strong	Genetic Variation	[1]
NRIP1	OTIZOJQV	Strong	Genetic Variation	[1]
PHGR1	OTY3GTEP	Strong	Altered Expression	[2]
TRAF3IP2	OTLLZERL	Strong	Genetic Variation	[1]
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References

1	Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway.Inflamm Bowel Dis. 2016 Apr;22(4):862-9. doi: 10.1097/MIB.0000000000000705.
2	The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer.Transl Oncol. 2018 Apr;11(2):436-443. doi: 10.1016/j.tranon.2018.01.015. Epub 2018 Feb 21.