Details of Drug Off-Target (DOT)
General Information of Drug Off-Target (DOT) (ID: OTCNC95Z)
DOT Name | Golgi-associated RAB2 interactor protein 5A (GARIN5A) | ||||
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Gene Name | GARIN5A | ||||
UniProt ID | |||||
3D Structure | |||||
Pfam ID | |||||
Sequence |
MGPPLWPDLQEPPPPGTSSQIRSPLLCDVIKPAPHHDVTVRVVPPPRFLPLLLRPLPSDG
DIAMRRDRGPKPALGGAGEVEPGGMAASPTGRPRRLQRYLQSGEFDQFRDFPIFESNFVQ FCPDIYPAPTSDLWPQVTRLGEVANEVTMGVAASSPALELPDLLLLAGPAKENGHLQLFG LFPLKFVQLFVHDKSRCQLEVKLNTSRTFYLQLRAPLKTRDREFGQWVRLLYRLRFLSAS AVPFTQE |
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Function | RAB2B effector protein which promotes cytosolic DNA-induced innate immune responses. Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis. | ||||
Molecular Interaction Atlas (MIA) of This DOT
Molecular Interaction Atlas (MIA) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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6 Drug(s) Affected the Gene/Protein Processing of This DOT
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References