Details of the Drug Combinations

General Information of This Drug (ID: DM0KYI4)

Drug Name

Mebutamate DM0KYI4

Synonyms

Dormate

Indication

Disease Entry	ICD 11	Status	REF
Anxiety disorder	6B00-6B0Z	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

117 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acarbose + Mebutamate	DCP9YPI	Acarbose	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Acetohexamide + Mebutamate	DCYD054	Acetohexamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Amodiaquine + Mebutamate	DC89NTG	Amodiaquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Anamorelin + Mebutamate	DC4YTBR	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Arfolitixorin + Mebutamate	DCM0WFE	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Asenapine + Mebutamate	DCLPA9O	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Bortezomib + Mebutamate	DCD5LYX	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Brincidofovir + Mebutamate	DC91OCO	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Buspirone + Mebutamate	DC140CO	Buspirone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cerivastatin + Mebutamate	DCYSUU4	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Chlorzoxazone + Mebutamate	DC02QFN	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cilostazol + Mebutamate	DCBDB3T	Cilostazol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Citalopram + Mebutamate	DC2G9WF	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clopidogrel + Mebutamate	DC7BGTI	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cycloguanil + Mebutamate	DCSO2UD	Cycloguanil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dantrolene + Mebutamate	DCWOH46	Dantrolene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Docetaxel + Mebutamate	DCHWXR8	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Doxorubicin + Mebutamate	DCMYVDO	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dronedarone + Mebutamate	DCHC1UV	Dronedarone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Emetine + Mebutamate	DCZ4CG2	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Epinephrine + Mebutamate	DCWVI24	Epinephrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Estramustine + Mebutamate	DCFEVOG	Estramustine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Everolimus + Mebutamate	DC3W6KF	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Fosfomycin + Mebutamate	DCPMC1I	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Furazolidone + Mebutamate	DCUL3WR	Furazolidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Gefitinib + Mebutamate	DCMK15N	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ginsenoside Rb1 + Mebutamate	DC2CTB2	Ginsenoside Rb1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Guanfacine + Mebutamate	DCFBT02	Guanfacine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Hydralazine + Mebutamate	DCPJ9SN	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Hyodeoxycholic acid + Mebutamate	DCVK1YP	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ibutilide + Mebutamate	DC8BKK2	Ibutilide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Idarubicin + Mebutamate	DCG92RD	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Itraconazole + Mebutamate	DC16WOF	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
L-165041 + Mebutamate	DCNRHAC	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Levamisole + Mebutamate	DC98M6B	Levamisole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Linagliptin + Mebutamate	DCK276G	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Lumefantrine + Mebutamate	DCTZPJO	Lumefantrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Maprotiline + Mebutamate	DC259TZ	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Aprepitant	DC1L73R	Aprepitant	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Ribavirin-TP	DCQMDVB	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Gefitinib	DCWNQI7	Gefitinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Kanamycin	DCHPD64	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Imipramine	DCXECK5	Imipramine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Epinephrine	DCCXDAG	Epinephrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Tindamax	DCM7ULO	Tindamax	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Furazolidone	DC71YBI	Furazolidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Tacrine	DCEZPCN	Tacrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Miglustat	DCWC0YK	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Anamorelin	DCTZ0TP	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Fomepizole	DCI8TF0	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Acitretin	DC67THK	Acitretin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Tranexamic acid	DCNCOWU	Tranexamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + IT-141	DC6193T	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Methylergonovine	DC3P62W	Methylergonovine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Buspirone	DC2WNKD	Buspirone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Terameprocol	DCIPYYH	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Cinacalcet	DCMM4ER	Cinacalcet	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Docetaxel	DCV9TQ6	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Galantamine	DCJ0DTM	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Fluspirilene	DCTCI5W	Fluspirilene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + WAY-100635	DCNMSNF	WAY-100635	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Dichlorphenamide	DCU94R3	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Diphenidol	DCTSTV6	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Pentamidine	DCMZX09	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Bosentan	DC8X5HA	Bosentan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Tolvaptan	DCITR33	Tolvaptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Arfolitixorin	DC6SHSO	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + BIO-300	DCVFAGO	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + PF-02545920	DC8X5E5	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Trazodone	DCWWI44	Trazodone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Oseltamivir	DCN7XYV	Oseltamivir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + GINKGOLIDE A	DC9Q88H	GINKGOLIDE A	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Diazoxide	DC6WLJR	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Imatinib	DC3PL11	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Moricizine	DC1X30U	Moricizine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Artemisinin	DCJAMDX	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Trimethobenzamide	DCX9X3O	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Leflunomide	DC42LEN	Leflunomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Acarbose	DCP3EY9	Acarbose	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Brincidofovir	DCPCUFG	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Sorafenib	DCTIDE0	Sorafenib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Loperamide	DC1RMA6	Loperamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Endoxifen	DCW526A	Endoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Mycophenolic acid	DCJ9JGC	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Pizotyline	DCAB56T	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Doxorubicin	DCCMG5N	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Auranofin	DCF9UOP	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Vorinostat	DCK4DB1	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Albendazole	DC5KFBL	Albendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Tetracycline	DCK289W	Tetracycline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mebutamate + Cytarabine	DC10E79	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mecamylamine + Mebutamate	DCXXN9A	Mecamylamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mefloquine + Mebutamate	DCTPBE6	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mephenytoin + Mebutamate	DCWBU9R	Mephenytoin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Methylene blue + Mebutamate	DC57H37	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mycophenolic acid + Mebutamate	DCV9B3N	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Olanzapine + Mebutamate	DC3S845	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Oxyphenbutazone + Mebutamate	DC96BH4	Oxyphenbutazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Palonosetron + Mebutamate	DCDLFIX	Palonosetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PHA-739358 + Mebutamate	DCPWX6O	PHA-739358	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Phenprocoumon + Mebutamate	DC6AUP2	Phenprocoumon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PMID28460551-Compound-2 + Mebutamate	DCEXCRJ	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PMID28870136-Compound-43 + Mebutamate	DC95HWJ	PMID28870136-Compound-43	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Probenecid + Mebutamate	DCAYY61	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pyrazinamide + Mebutamate	DCOTSCS	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Mebutamate	DC46F86	Quinine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ribavirin-TP + Mebutamate	DC0ACNT	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Rufinamide + Mebutamate	DCWENQE	Rufinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
SCH 727965 + Mebutamate	DCG9CYR	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sertraline + Mebutamate	DCRTXZR	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sitagliptin + Mebutamate	DCVW1N1	Sitagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Terazosin + Mebutamate	DC39ITG	Terazosin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Testosterone cypionate + Mebutamate	DCE8C2F	Testosterone cypionate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Tiagabine + Mebutamate	DCN1TVE	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Triapine + Mebutamate	DCHKZWG	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trihexyphenidyl + Mebutamate	DCD6AJO	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Vinblastine + Mebutamate	DCGG3V1	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
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⏷ Show the Full List of 117 DrugCom(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3	Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.