Details of the Drug Combinations

General Information of This Drug (ID: DM1AF5U)

Drug Name
Acetazolamide   DM1AF5U
Synonyms
Acetadiazol; Acetamidothiadiazolesulfonamide; Acetamox; Acetazolam; Acetazolamid; Acetazolamida; Acetazolamidum; Acetazolamine; Acetazoleamide; Acetozalamide; AkZol; ApoAcetazolamide; Atenezol; Cidamex; Dazamide; Defiltran; Dehydratin; Diacarb; Diakarb; Diamox; Didoc; Diluran; Diuramid; Diuramide; Diuriwas; Diutazol; Donmox; Duiramid; Edemox; Eumicton; Fonurit; Glauconox; Glaumox; Glaupax; Glupax; HumaZolamide; Natrionex; Nephramid; Nephramide; Phonurit; Storzolamide; Vetamox; Acetazolamide Apotex Brand; Acetazolamide Chiesi Brand; Acetazolamide Dioptic Brand; Acetazolamide Grin Brand; Acetazolamide ICN Brand; Acetazolamide Jumer Brand; Acetazolamide Llorens Brand; Acetazolamide Medphano Brand; Acetazolamide Novopharm Brand; Acetazolamide Orion Brand; Acetazolamide Wassermann Brand; Ak Zol; Apo Acetazolamide; Apotex Brand of Acetazolamide; Chiesi Brand of Acetazolamide; Ciba Vision Brand of Acetazolamide; DiamoxSequels; Dioptic Brand of Acetazolamide; Grin Brand of Acetazolamide; Huma Zolamide; ICN Brand of Acetazolamide; Jumer Brand of Acetazolamide; Llorens Brand of Acetazolamide; Medphano Brand of Acetazolamide; Monosodium Salt Acetazolamide; Novopharm Brand of Acetazolamide; Orion Brand of Acetazolamide; Storz Brand of Acetazolamide Preparation; Wassermann Brand of Acetazolamide; Wyeth Brand of Acetazolamide Preparation; A 6011; Carbonic anhydrase inhibitor 6063; Acetazolamida [INN-Spanish]; Acetazolamide (AAZ); Acetazolamide, Monosodium Salt; Acetazolamidum [INN-Latin]; Ak-Zol; Apo-Acetazolamide; Carbonic Anhydrase Inhibitor No. 6063; Diamox (TN); Diureticum-holzinger; Huma-Zolamide; SK-acetazolamide; Acetazolamide Sodium, (Sterile); Acetazolamide [INN:BAN:JAN]; Acetazolamide (JP15/USP/INN); 4-Diamox
Indication
Disease Entry ICD 11 Status REF
Absence epilepsy N.A. Approved [1]
Altitude sickness N.A. Approved [1]
Edema MG29 Approved [1]
Glaucoma/ocular hypertension 9C61 Approved [2]
Therapeutic Class
Anticonvulsants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

59 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Acetazolamide DC28POI Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Sertraline DCFOOX7 Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Gefitinib DCLTPAM Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Dantrolene DCON6T7 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Epinephrine DCGG3NA Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Vinblastine DCGQGF0 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Ramelteon DCJR6B9 Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Triapine DCZR1SC Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Everolimus DC168S3 Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Metyrosine DCGRA78 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Guanfacine DC0XVER Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Chlorzoxazone DC8RIG3 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Pazopanib DCBQKY0 Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Tolazoline DC0KF63 Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Bosentan DC3MY34 Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Arfolitixorin DCT004B Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + BIO-300 DCVZNNM BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Norcisapride DC9P6XB Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Diazoxide DCQH4TP Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Idarubicin DC2MWY7 Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Imatinib DCI5QJP Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Darunavir DCF0NV3 Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Moricizine DC8CIG8 Moricizine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Leflunomide DCNXV2S Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Brincidofovir DCKXUXF Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Mycophenolic acid DCOWE9H Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Mefloquine DC01VCC Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Doxorubicin DCS5ATN Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Rufinamide DCJH91J Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Vorinostat DCMRWPF Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Enoxacin DCKR3UJ Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Raltegravir DCCU0B9 Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetazolamide + Cytarabine DC8AV5H Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amodiaquine + Acetazolamide DC6T25W Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Anamorelin + Acetazolamide DCYPL6E Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Acetazolamide DCZCD9Z Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Carglumic acid + Acetazolamide DCVUTS0 Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cefmenoxime + Acetazolamide DCP0IQ9 Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Acetazolamide DCMSRYJ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ciprofibrate + Acetazolamide DCUCBEQ Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diphenidol + Acetazolamide DC4IA5I Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Emetine + Acetazolamide DCZNBGZ Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enalaprilat + Acetazolamide DCHHPGS Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Eptifibatide + Acetazolamide DC4UXDA Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Estramustine + Acetazolamide DC3UA11 Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
ETHISTERONE + Acetazolamide DCVYTVH ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Acetazolamide DCNJXVO Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Furazolidone + Acetazolamide DCXWAYS Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hyodeoxycholic acid + Acetazolamide DCDG8FQ Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lefaxin + Acetazolamide DCRHVLE Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Acetazolamide DCPRE37 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Acetazolamide DCLUUSQ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methoxsalen + Acetazolamide DCM7G4L Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Nabilone + Acetazolamide DCRP127 Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28460551-Compound-2 + Acetazolamide DCHFIOE PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terameprocol + Acetazolamide DCPJKNR Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Testosterone cypionate + Acetazolamide DCQI0MQ Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tranexamic acid + Acetazolamide DCPU4EQ Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tropisetron + Acetazolamide DCWAMTM Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 59 DrugCom(s)
6 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Acetazolamide + Hydroxyurea DC1ENCQ Hydroxyurea Thalassemia [4]
Acetazolamide + Buspirone DC4VF9L Buspirone Central Apnea [5]
Acetazolamide + Acetylcysteine DCPK6P9 Acetylcysteine Erythrocytosis [6]
Acetazolamide + Temozolomide DCVU3SE Temozolomide Malignant Glioma of Brain [7]
Acetazolamide + Nimodipine DC5K4SC Nimodipine Acute Cerebrovascular Accident [8]
Acetazolamide + Famotidine DCO6YIA Famotidine Acute Cerebrovascular Accident [9]
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⏷ Show the Full List of 6 DrugCom(s)

References

1 Acetazolamide FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6792).
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT03715972) Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia
5 ClinicalTrials.gov (NCT00746954) Buspirone as a Potential Treatment for Recurrent Central Apnea
6 ClinicalTrials.gov (NCT01187108) Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru
7 ClinicalTrials.gov (NCT03011671) Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma
8 ClinicalTrials.gov (NCT02165644) Carbonic Anhydrase Antagonism in Subarachnoid Hemorrhage
9 ClinicalTrials.gov (NCT02142712) Histamine Glutamate Antagonism in Stroke