Details of the Drug Combinations

General Information of This Drug (ID: DMOL54H)

Drug Name
Clopidogrel   DMOL54H
Synonyms
clopidogrel; 113665-84-2; (S)-Clopidogrel; Plavix; Clopidogrel [INN:BAN]; (+)-(S)-Clopidogrel; (+)-Clopidogrel; UNII-A74586SNO7; HSDB 7430; CLOPIDOGREL SULFATE; CHEBI:37941; GKTWGGQPFAXNFI-HNNXBMFYSA-N; A74586SNO7; CPD000550475; Zyllt; Clopidogrel (TN); SR-25990C; Plavix (TN); methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate; Clopidogrelum; Thrombo; Clopidogrel BMS; Clopidogrel Hexal; Clopidogrel Acino; methyl (2S)-2-(2-chlorophenyl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}acetate; PM-103; Clopidogrel (captisol-enabled); Clopidogrel (captisol-enabled), The Medicines Co; Clopidogrel (captisol-enabled, cardiovascular disease), Cydex; Clopidogrel (captisol-enabled, cardiovascular disease), Prism Pharmaceuticals
Indication
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [1]
Atherosclerosis BD40 Approved [1]
Myocardial infarction BA41-BA43 Approved [1]
Thrombosis DB61-GB90 Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [3]
Intracranial embolism 8B22.1 Investigative [1]
⏷ Show the Full List of Indication(s)
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

93 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Clopidogrel DCC54HH 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Acamprosate + Clopidogrel DCOA82L Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Arfolitixorin + Clopidogrel DCMX0MB Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Armodafinil + Clopidogrel DC9T8PF Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Bepridil + Clopidogrel DCHBHQO Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
BHV-0223 + Clopidogrel DCFEYM2 BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Brincidofovir + Clopidogrel DCI9MUH Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Cerivastatin + Clopidogrel DC94F3S Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Chlorzoxazone + Clopidogrel DCJX12X Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Mebutamate DC7BGTI Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Gefitinib DCHXIAX Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Imipramine DCUKINA Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Tindamax DCSPQSD Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + PMID28460551-Compound-2 DCVS9N0 PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Vinblastine DCHR70S Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Anamorelin DCP0FCA Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Fomepizole DC5O5NY Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Triapine DC9DQ0P Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Acitretin DC3HPPH Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Metyrosine DC7ATU1 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Guanfacine DC1C7RV Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Itraconazole DCCVCJ9 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Doxapram DCBF2RN Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Docetaxel DC9BXF4 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Tolvaptan DCD9JGA Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Arfolitixorin DCQR5V1 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + BIO-300 DCDTXZR BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + PF-02545920 DCJKFPC PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Trifluoperazine DCV5YDW Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Diazoxide DC1Z1RO Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Tamoxifen DCN174U Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Allopurinol DCWNHL6 Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Idarubicin DCETDSR Idarubicin Glioblastoma? (Cell Line: T98G) [4]
Clopidogrel + BRL-15572 DC6492O BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Imatinib DC1EVEN Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Darunavir DC7SS7A Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Pramipexole DCINF0Z Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Bortezomib DCGW3CE Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Methylene blue DCGEG0F Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Mesalazine DC3T6AO Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Maprotiline DCD4MHS Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Teriflunomide DCE0095 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Leflunomide DCR6NYD Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Brincidofovir DCT1LKK Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Hyodeoxycholic acid DCCQBLA Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Quinine DCN290Z Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Mycophenolic acid DCYWKWH Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Mefloquine DCFZHZR Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Doxorubicin DC844NY Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Olmesartan medoxomil DCSG06E Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Auranofin DCQQCD5 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Cerivastatin DCUKWBF Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Acetohydroxamic Acid DCE7SWH Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Albendazole DC6QART Albendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + AS-1949490 DCDXZP0 AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + GSK2194069 DCGIT1B GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Nitrosoglutathione DCZI4R8 Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Clopidogrel + Cytarabine DC3H5T1 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Crotamiton + Clopidogrel DCMTWMR Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Dantrolene + Clopidogrel DCA251E Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Darunavir + Clopidogrel DCKG8GR Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Diazoxide + Clopidogrel DCO09NO Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Diphenidol + Clopidogrel DCBB8AB Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Dopamine + Clopidogrel DCPCBUW Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Doxorubicin + Clopidogrel DCO8EKP Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Dronedarone + Clopidogrel DC84O6C Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Endoxifen + Clopidogrel DCA4M35 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Epinephrine + Clopidogrel DC6WYAE Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Etomidate + Clopidogrel DCOU6GU Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Everolimus + Clopidogrel DCL6PVW Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Fluspirilene + Clopidogrel DCDD45C Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Gefitinib + Clopidogrel DCOMDF3 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Idarubicin + Clopidogrel DCLRKVU Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Kanamycin + Clopidogrel DCJ33P5 Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
L-165041 + Clopidogrel DCPVU5Q L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Levamisole + Clopidogrel DCZDIK7 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Maprotiline + Clopidogrel DCWVRAF Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Metformin + Clopidogrel DC65ENX Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Methotrexate + Clopidogrel DCAEP3X Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Methylene blue + Clopidogrel DCEOM7U Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Methylergonovine + Clopidogrel DCGZVX6 Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Metyrosine + Clopidogrel DCUFWFT Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Mycophenolic acid + Clopidogrel DCXTWOQ Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Pargyline + Clopidogrel DC3QTLV Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Pazopanib + Clopidogrel DCPLC58 Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Pramipexole + Clopidogrel DC9LG8E Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Pyrazinamide + Clopidogrel DC01WJP Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
SCH 727965 + Clopidogrel DC86TDM SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Sumatriptan + Clopidogrel DC30EH3 Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Tacrine + Clopidogrel DCBV4FS Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Tiagabine + Clopidogrel DCU47WI Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Vorinostat + Clopidogrel DCJ95TB Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Zileuton + Clopidogrel DCYJGS4 Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
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⏷ Show the Full List of 93 DrugCom(s)
16 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Aspirin + Clopidogrel DCQH23M Aspirin Atrial Fibrillation [5]
Aspirin + Clopidogrel DCC6XJC Aspirin Cerebrovascular Accident [6]
Aspirin + Clopidogrel DCVBZBK Aspirin Acute Coronary Disease [7]
Brilinta + Clopidogrel DCKADAS Brilinta Coronary Artery Disease [8]
Clopidogrel + Ramipril DCFN2J8 Ramipril Diabetes Type 2 [9]
Edivoxetine + Clopidogrel DCBBQ0A Edivoxetine Major Depressive Disorder [10]
Prasugrel + Clopidogrel DCJ48H7 Prasugrel Acute Coronary Syndrome [11]
Cangrelor + Clopidogrel DC7GMFR Cangrelor Coronary Artery Disease (CAD) [12]
Clopidogrel + Rivaroxaban DC3DY4X Rivaroxaban Acute Coronary Syndrome [13]
Clopidogrel + Eptifibatide DC5PNLP Eptifibatide Acute Coronary Syndrome [14]
DU-176B + Clopidogrel DCMNVOC DU-176B SCAD [15]
Brilinta + Clopidogrel DC6WLZ2 Brilinta Coronary Artery Disease [16]
Prasugrel + Clopidogrel DCB552G Prasugrel Coronary Artery Disease [17]
Aspirin + Clopidogrel DC9DJGY Aspirin Acute Coronary Syndrome [18]
Aspirin + Clopidogrel DCZZ2VC Aspirin Hypertension [19]
Clopidogrel + Rivaroxaban DC2I0J8 Rivaroxaban Atrial Fibrillation [20]
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⏷ Show the Full List of 16 DrugCom(s)

References

1 Clopidogrel FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7150).
3 Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial. (C-19-ACS)
4 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5 ClinicalTrials.gov (NCT05960721) Low-dose NOAC Versus GDMT After LAAO
6 ClinicalTrials.gov (NCT00059306) Secondary Prevention of Small Subcortical Strokes Trial
7 ClinicalTrials.gov (NCT00335452) Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
8 ClinicalTrials.gov (NCT01742117) Tailored Antiplatelet Therapy Following PCI
9 ClinicalTrials.gov (NCT01743014) Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy
10 ClinicalTrials.gov (NCT01263093) A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel
11 ClinicalTrials.gov (NCT01115738) Clopidogrel to Prasugrel in Acute Coronary Syndrome (ACS) Patients
12 ClinicalTrials.gov (NCT01979445) Cangrelor to Clopidogrel or Prasugrel Transition Study
13 ClinicalTrials.gov (NCT02293395) A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome
14 ClinicalTrials.gov (NCT02925923) Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel
15 ClinicalTrials.gov (NCT05122455) Effects of Edoxaban on Platelet Aggregation
16 ClinicalTrials.gov (NCT01805596) Effect of Ticagrelor on Endothelial Function
17 ClinicalTrials.gov (NCT01598337) The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency
18 ClinicalTrials.gov (NCT05573958) To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome
19 ClinicalTrials.gov (NCT02594410) Zainidip in Renal Artery Stenosis
20 ClinicalTrials.gov (NCT04023630) DUAL Antithrombotic Therapy in Patients With AF and ACS