Details of the Drug Combinations

General Information of This Drug (ID: DMPLY7B)

Drug Name
Cefmenoxime   DMPLY7B
Synonyms
Cefmax; Cefmenoxima; Cefmenoximum; Tacef; Cefmenoxime [INN]; A 50912; AB 50912; SCE 1365; Abbott-50192; Cefmenoxima [INN-Spanish]; Cefmenoxime (INN); Cefmenoximum [INN-Latin]; Cefmenoxime Hydrochloride (2:1); (6R,7R)-(2-(2-Amino-4-thiazolyl)glyoxylamido)-3-(1-methyl-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure-7-(Z)-(O-methyloxim); (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure; (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (IUPAC); (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Approved [1]
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

56 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Cefmenoxime DCSUFZH Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aciclovir + Cefmenoxime DCFBEBE Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acitretin + Cefmenoxime DCRI67B Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Amiloride + Cefmenoxime DCAFP34 Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
AS-1949490 + Cefmenoxime DCUF9RP AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Auranofin + Cefmenoxime DCT9Y8D Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Cefmenoxime DCHN9TH Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bosentan + Cefmenoxime DC9QK69 Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Cefmenoxime DCJ7N41 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Aprepitant DC07ZLP Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Ribavirin-TP DC2D8UL Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Pentostatin DC5KP6O Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Triiodothyronine DCK9IRR Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Gefitinib DC015H2 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Acetazolamide DCP0IQ9 Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Epinephrine DCDQ8KQ Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Terameprocol DCGA0FA Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Metformin DCBAYR2 Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Fibrates DCSVC56 Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Sulfapyridine DC6K9OX Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Arfolitixorin DCPNR5P Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Tiagabine DCGS02C Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Diazoxide DCBS375 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Fenoprofen DCV5RTL Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Idarubicin DCYE7CH Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Idarubicin DCF7EZG Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Cefmenoxime + Imatinib DCGBVZV Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Pramipexole DC8TGWL Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Artemisinin DCDURQI Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Topotecan DCC80WZ Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Theophylline DC981WL Theophylline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Sorafenib DCCD1AL Sorafenib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Naltrexone DCERW5C Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Quinine DCTI27H Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Hydralazine DCWXH0N Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Cisatracurium DC6GXE8 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Silver sulfadiazine DCPAOR6 Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + Cerivastatin DCS6PIF Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cefmenoxime + ML323 DCGSZ8O ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorzoxazone + Cefmenoxime DCE17JD Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Cefmenoxime DC4QYFV Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Cefmenoxime DC2L6VX Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + Cefmenoxime DCZOOL9 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Cefmenoxime DCT0B7G Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Endoxifen + Cefmenoxime DCYXER7 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
ETHISTERONE + Cefmenoxime DCA0JQX ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Cefmenoxime DCWR8QU L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Cefmenoxime DCHN8O6 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
LY03004 + Cefmenoxime DC3WEM1 LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Cefmenoxime DC0B7CK Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metaxalone + Cefmenoxime DC8JG66 Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylene blue + Cefmenoxime DCZ2TLH Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Cefmenoxime DCITIF0 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Spironolactone + Cefmenoxime DCTTHWH Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + Cefmenoxime DCO0CE6 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Valproic Acid + Cefmenoxime DCLUHB4 Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 56 DrugCom(s)

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.