Details of the Drug Combinations

General Information of This Drug (ID: DMZTXCH)

• Drug Name: Remifentanil (DMZTXCH)
• Synonyms: Remifentanyl; Ultiva; GI 87084B; GI 87084X; GI87084B; Remifentanil (INN); Remifentanil [INN:BAN]; Ultiva (TN); Methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate; 1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester; 3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester; 4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester

Indication

Anaesthesia; ICD 11: 9A78.6; Status: Approved [1]

• Therapeutic Class: Hypnotics and Sedatives
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

22 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Butorphanol + Remifentanil	DCO6TRQ	Butorphanol	Pain	[2]
Cannabidiol + Remifentanil	DCEFAFV	Cannabidiol	Acute Nociceptive Pain	[3]
Desflurane + Remifentanil	DCVDVMF	Desflurane	Cholecystitis	[4]
Fentanyl + Remifentanil	DCMME74	Fentanyl	Postoperative Pain	[5]
Ibuprofen + Remifentanil	DCP2ON0	Ibuprofen	Ibuprofen	[6]
Lidocaine + Remifentanil	DCBSUXF	Lidocaine	Cough	[7]
Midazolam + Remifentanil	DCPYZVG	Midazolam	Peripheral Arterial Occlusive Disease	[8]
Oxycodone + Remifentanil	DC5EYQY	Oxycodone	Opioid Use Disorder	[9]
Pregabalin + Remifentanil	DCRS086	Pregabalin	Pain	[10]
Propofol + Remifentanil	DC0JZTT	Propofol	Lung Function	[11]
Propofol + Remifentanil	DCKE1SL	Propofol	Parkinson's Disease	[12]
Remimazolam + Remifentanil	DC7FJ8J	Remimazolam	Anesthesia	[13]
Morphine + Remifentanil	DC73E55	Morphine	Progressive Infantile Idiopathic Scoliosis	[14]
Lidocaine + Remifentanil	DC77CLY	Lidocaine	Stroke	[15]
Desflurane + Remifentanil	DC84HKW	Desflurane	Anesthesia	[16]
Fentanyl + Remifentanil	DC7M5DK	Fentanyl	Chronic Pain	[17]
Ketamine + Remifentanil	DCNHCDZ	Ketamine	Delayed Emergence From Anesthesia	[18]
Ketamine + Remifentanil	DCZOOOT	Ketamine	Pediatric Rigid Bronchoscopy	[19]
Midazolam + Remifentanil	DCCJYP4	Midazolam	Critical Illness	[20]
Propofol + Remifentanil	DC2405N	Propofol	Target Controlled Infusion	[21]
Sevoflurane + Remifentanil	DC88V2F	Sevoflurane	Haemodynamic Rebound	[22]
Sevoflurane + Remifentanil	DCO1IZT	Sevoflurane	Intra-abdominal and Intrapelvic Surgery	[23]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7292).
• [2] ClinicalTrials.gov (NCT02043366) Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients
• [3] ClinicalTrials.gov (NCT04059978) Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults
• [4] ClinicalTrials.gov (NCT01937104) ONSD According to the Position During Laparoscopy
• [5] ClinicalTrials.gov (NCT02619032) Remifentanil and Fentanyl in Dental Surgery (REFEDS)
• [6] ClinicalTrials.gov (NCT02243254) Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen
• [7] ClinicalTrials.gov (NCT04455711) The Effect of Lidocaine on Smooth Emergence With Double Lumen Tube
• [8] ClinicalTrials.gov (NCT02929095) The Effect of Remifentanil-dexmedetomidine Compared With Remifentanil-midazolam on Patient's Satisfaction
• [9] ClinicalTrials.gov (NCT03958474) Neurobehavioral Mechanisms of Choice in Opioid Use Disorder
• [10] ClinicalTrials.gov (NCT01419405) Pregabalin and Remifentanil - Analgesia and Ventilation
• [11] ClinicalTrials.gov (NCT00706277) Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function
• [12] ClinicalTrials.gov (NCT00615472) Intravenous Versus Inhalational Anesthesia in Parkinson's Disease
• [13] ClinicalTrials.gov (NCT04670471) Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil
• [14] ClinicalTrials.gov (NCT02571491) Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery
• [15] ClinicalTrials.gov (NCT02822144) General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke
• [16] ClinicalTrials.gov (NCT02379715) Effect-site Concentration of Remifentanil for Smooth Induction With Desflurane
• [17] ClinicalTrials.gov (NCT02031016) Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
• [18] ClinicalTrials.gov (NCT02602743) Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy
• [19] ClinicalTrials.gov (NCT01947114) Remifentanil Use in Pediatric Rigid Bronchoscopy
• [20] ClinicalTrials.gov (NCT02635802) the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation
• [21] ClinicalTrials.gov (NCT02999126) Slow Stepwise Propofol TCI Induction for Titration Anesthesia Maintenance
• [22] ClinicalTrials.gov (NCT02271555) The Effects of Remifentanil on Attenuating the Hemodynamic Responses After Electroconvulsive Therapy
• [23] ClinicalTrials.gov (NCT01809041) Comparison of Intravenous Anesthetics to Volatile Anesthetics on Postoperative Cognitive Dysfunction