Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3ZHBO)

Drug Name

N'-Pyridoxyl-Lysine-5'-Monophosphate Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Cystathionine gamma-synthase (Bact metB)	TTDU0HP	METB_ECOLI	Inhibitor	[1]
Glycogen phosphorylase muscle form (GP)	TTZHY6R	PYGM_HUMAN	Inhibitor	[1]
Ornithine decarboxylase (ODC1)	TTUMGNO	DCOR_HUMAN	Inhibitor	[1]
Pseudomonas Methionine gamma-lyase (Pseudo mdeA)	TT1UY5C	MEGL_PSEPU	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Glycogen phosphorylase muscle form (GP)	DTT	PYGM	4.036	5.34	6.256	6.062
Ornithine decarboxylase (ODC1)	DTT	ODC1	9.956	8.598	9.482	8.752

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glycogen phosphorylase muscle form (GP)	DTT	PYGM	2.69E-01	-0.23	-0.14

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.